A 45-Amino-Acid Scaffold Mined from the PDB for High-Affinity Ligand Engineering

Keyphrases

• Amino Acids 100%
• Ligand Engineering 100%
• High-affinity Ligands 100%
• Cancer Targeting 50%
• Directed Evolution 50%
• Epidermal Growth Factor Receptor 50%
• Ligand Discovery 50%
• Specific Binding 50%
• Helix 50%
• Enhanced Stability 50%
• Binder 50%
• Systematic Evaluation 50%
• Conjugation 50%
• Binding Function 50%
• High Thermal Stability 50%
• Thermal Denaturation 50%
• Antibody Stability 50%
• Physiological Distribution 50%
• T7 Phage 50%
• Small Protein 50%
• Protein-ligand 50%
• Ligand Scaffold 50%

Biochemistry, Genetics and Molecular Biology

• Amino Acids 100%
• Thermostability 100%
• Protein Ligand 100%
• Receptor Affinity 100%
• Enterobacteria Phage T7 100%
• Denaturation 100%
• Epidermal Growth Factor Receptor 100%