A 1-year follow-up of a multi-center treatment trial of adults with anorexia nervosa

Jessica Yu, W. Stewart Agras, K. A. Halmi, S. Crow, J. Mitchell, S. W. Bryson

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


OBJECTIVE: To examine maintenance of recovery following treatment in an adult anorexia nervosa (AN) population. METHOD: One year follow-up of a randomized clinical trial with 122 participants treated with: cognitive behavioral therapy (CBT), drug therapy (fluoxetine), or a combination (CBT+fluoxetine) for 12 months. Participants were assessed at baseline, end of treatment, and follow-up. The primary outcomes were weight and the global scores from the Eating Disorder Examination (EDE) separately and combined. RESULTS: Fifty-two participants completed the follow-up. Mean weight increased from end of treatment to follow-up. Seventy-five percent (75%) of those weight recovered at end of treatment maintained this recovery at follow-up. Recovery of eating disorder psychopathology was stable from end of treatment to follow-up, with 40% of participants with a global EDE score within normal range. Using the most stringent criteria for recovery, only 21% of the completer sample was recovered. DISCUSSION: The findings suggest that while adults with AN improve with treatment and maintain these improvements during follow-up, the majority is not recovered. Additionally, further research is needed to understand barriers to treatment and assessment completion.

Original languageEnglish (US)
Pages (from-to)e177-e181
JournalEating and Weight Disorders
Issue number3
StatePublished - Sep 2011


  • Adult anorexia
  • Eating disorders examination
  • Follow-up
  • Maintenance
  • Percent ideal body weight
  • Recovery


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