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• 2019

  Treatment combining CD200 immune checkpoint inhibitor and tumor-lysate vaccination after surgery for pet dogs with high-grade glioma

  Olin, M. R., Ampudia-Mesias, E., Pennell, C. A., Sarver, A., Chen, C. C., Moertel, C. L., Hunt, M. A. & Pluhar, G. E., Jan 1 2019, In: Cancers. 11, 2, 137.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pets
  • Glioma
  • Vaccination
  • Dogs
  • Antigen-Presenting Cells
  10 Scopus citations

• Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

  Rosato, P. C., Wijeyesinghe, S., Stolley, J. M., Nelson, C. E., Davis, R. L., Manlove, L. S., Pennell, C. A., Blazar, B. R., Chen, C. C., Geller, M. A., Vezys, V. & Masopust, D., Dec 1 2019, In: Nature communications. 10, 1, 567.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • T-cells
  • Viruses
  • Tumors
  • tumors
  • Immunotherapy
  51 Scopus citations

• When less is more: Gaining power through gene rearrangement of amplified EGFR

  Koga, T., Chen, C. C. & Furnari, F. B., Mar 1 2019, In: Oncotarget. 10, 22, p. 2116-2117 2 p.

  Research output: Contribution to journal › Editorial › peer-review
• 2020

  Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells (Nature Communications, (2020), 11, 1, (550), 10.1038/s41467-020-14312-1)

  Koga, T., Chaim, I. A., Benitez, J. A., Markmiller, S., Parisian, A. D., Hevner, R. F., Turner, K. M., Hessenauer, F. M., D’Antonio, M., Nguyen, N. P. D., Saberi, S., Ma, J., Miki, S., Boyer, A. D., Ravits, J., Frazer, K. A., Bafna, V., Chen, C. C., Mischel, P. S., Yeo, G. W. & 1 others, Furnari, F. B., Dec 1 2020, In: Nature communications. 11, 1, 1958.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • stem cells
  • Pluripotent Stem Cells
  • Tumors
  • tumors
  • cancer

• Cost-effectiveness of stereotactic laser ablation (SLA) for brain tumors

  Dhawan, S., Bartek, J. & Chen, C. C., Jul 15 2020, In: International Journal of Hyperthermia. 37, 2, p. 61-67 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Laser Therapy
  • Cost-Benefit Analysis
  • Craniotomy
  • Lasers
  • Hot Temperature
  1 Scopus citations

• Devascularization of a Hemorrhagic Pineocytoma by Laser Thermal Ablation Followed by Endoscopic Resection: A Proof-of-Principle Case Report

  Freeman, D., Guillaume, D., Bell, W. R. & Chen, C. C., Jul 2020, In: World neurosurgery. 139, p. 583-587 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Pinealoma
  • Laser Therapy
  • Hot Temperature
  • Surgical Hemostasis
  • Stereotaxic Techniques
  1 Scopus citations

• Early versus delayed postoperative radiotherapy for treatment of low-grade gliomas

  Dhawan, S., Patil, C. G., Chen, C. & Venteicher, A. S., Jan 20 2020, In: Cochrane Database of Systematic Reviews. 2020, 1, CD009229.

  Research output: Contribution to journal › Article › peer-review

  • Glioma
  • Radiotherapy
  • Therapeutics
  • Headache
  • Radiation
  10 Scopus citations

• Effect of Vocimagene Amiretrorepvec in Combination with Flucytosine vs Standard of Care on Survival following Tumor Resection in Patients with Recurrent High-Grade Glioma: A Randomized Clinical Trial

  Cloughesy, T. F., Petrecca, K., Walbert, T., Butowski, N., Salacz, M., Perry, J., Damek, D., Bota, D., Bettegowda, C., Zhu, J. J., Iwamoto, F., Placantonakis, D., Kim, L., Elder, B., Kaptain, G., Cachia, D., Moshel, Y., Brem, S., Piccioni, D., Landolfi, J. & 10 others, Chen, C. C., Gruber, H., Rao, A. R., Hogan, D., Accomando, W., Ostertag, D., Montellano, T. T., Kheoh, T., Kabbinavar, F. & Vogelbaum, M. A., Dec 2020, In: JAMA Oncology. 6, 12, p. 1939-1946 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Flucytosine
  • Standard of Care
  • Glioma
  • Randomized Controlled Trials
  • Survival
  6 Scopus citations

• Epidermal Growth Factor Receptor (EGFR) as a molecular determinant of glioblastoma response to dopamine receptor 2 (DRD2) inhibitors.

  He, Y., Li, J., Koga, T., Ma, J., Dhawan, S., Suzuki, Y., Furnari, F., Prabhu, V. V., Allen, J. & Chen, C. C., Aug 2020, In: Neuro-Oncology.

  Research output: Contribution to journal › Article › peer-review

• Epidermal growth factor receptor expression as a molecular determinant of glioblastoma response to the dopamine receptor D2 antagonist.

  He, Y., Ma, J., Dhawan, S., Koga, T., Furnari, F., Prabhu, V. V., Allen, J. & Chen, C. C., 2020.

  Research output: Contribution to conference › Poster

  • Dopamine D2 Receptor Antagonists
  • Glioblastoma
  • ErbB Receptors

• Frame-Based Stereotactic Endoscopic Third Ventriculostomy—Toward Improved Precision and Minimizing Morbidities

  Chen, C. C., Freeman, D. & Warnke, P. C., Aug 2020, In: World neurosurgery. 140, p. e240-e246

  Research output: Contribution to journal › Article › peer-review

  • Ventriculostomy
  • Anatomy
  • Morbidity
  • Stereotaxic Techniques
  • Third Ventricle

• GammaTile^®: Surgically targeted radiation therapy for glioblastomas

  Gessler, D. J., Ferreira, C., Dusenbery, K. & Chen, C. C., Oct 2020, In: Future Oncology. 16, 30, p. 2445-2455 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Glioblastoma
  • Radiation
  • Brachytherapy
  • Radiotherapy
  • Seeds
  4 Scopus citations

• GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway

  Yu, S., Yu, X., Sun, L., Zheng, Y., Chen, L., Xu, H., Jin, J., Lan, Q., Chen, C. C. & Li, M., Jul 2 2020, In: Oncogene. 39, 27, p. 5042-5055 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Glioblastoma
  • Fibronectins
  • Carrier Proteins
  • GTP Phosphohydrolases
  • Tumor Cell Line
  2 Scopus citations

• Genome engineering evolves brain tumor modeling

  Koga, T., Chen, C. C. & Furnari, F. B., 2020, In: Neurologia Medico-Chirurgica. 60, 7, p. 329-336 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome
  • Mutation
  • Glioblastoma
  • Neoplasms
  • Typical Teratoid Rhabdoid Tumor
  1 Scopus citations

• Glioblastomas located in proximity to the subventricular zone (SVZ) exhibited enrichment of gene expression profiles associated with the cancer stem cell state

  Steed, T. C., Treiber, J. M., Taha, B., Engin, H. B., Carter, H., Patel, K. S., Dale, A. M., Carter, B. S. & Chen, C. C., Jul 1 2020, In: Journal of neuro-oncology. 148, 3, p. 455-462 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lateral Ventricles
  • Neoplastic Stem Cells
  • Glioblastoma
  • Transcriptome
  • Stem Cells
  3 Scopus citations

• Hemorrhagic Complications of Invasive Intracranial Pressure Monitor Placement in Acute Liver Failure: Outcomes of a Single-Center Protocol and Comprehensive Literature Review

  Jinadasa, S. P., Ruan, Q. Z., Bayoumi, A. B., Sharma, S. V., Boone, M. D., Malik, R., Chen, C. C. & Kasper, E. M., 2020, (Accepted/In press) In: Neurocritical Care.

  Research output: Contribution to journal › Article › peer-review

  • Acute Liver Failure
  • Hemorrhage
  • Intracranial Hypertension
  • Brain Edema
  • Chronology

• Laser ablation of abnormal neurological tissue using robotic neuroblate system (laantern): Procedural safety and hospitalization

  Rennert, R. C., Khan, U., Bartek, J., Tatter, S. B., Field, M., Toyota, B., Fecci, P. E., Judy, K., Mohammadi, A. M., Landazuri, P., Sloan, A. E., Kim, A. H., Leuthardt, E. C. & Chen, C. C., Apr 1 2020, In: Neurosurgery. 86, 4, p. 538-547 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Laser Therapy
  • Robotics
  • Hospitalization
  • Safety
  • Intensive Care Units
  8 Scopus citations

• Laser ablation of abnormal neurological tissue using robotic neuroblate system (laantern): 12-month outcomes and quality of life after brain tumor ablation

  Kim, A. H., Tatter, S., Rao, G., Prabhu, S., Chen, C., Fecci, P., Chiang, V., Smith, K., Williams, B. J., Mohammadi, A. M., Judy, K., Sloan, A., Tovar-Spinoza, Z., Baumgartner, J., Hadjipanayis, C. & Leuthardt, E. C., Sep 1 2020, In: Neurosurgery. 87, 3, p. E338-E346

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Laser Therapy
  • Robotics
  • Quality of Life
  • Lasers
  • Registries
  5 Scopus citations

• Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

  Koga, T., Chaim, I. A., Benitez, J. A., Markmiller, S., Parisian, A. D., Hevner, R. F., Turner, K. M., Hessenauer, F. M., D’Antonio, M., Nguyen, N. P. D., Saberi, S., Ma, J., Miki, S., Boyer, A. D., Ravits, J., Frazer, K. A., Bafna, V., Chen, C. C., Mischel, P. S., Yeo, G. W. & 1 others, Furnari, F. B., Dec 1 2020, In: Nature communications. 11, 1, 550.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • stem cells
  • Pluripotent Stem Cells
  • Tumors
  • tumors
  • cancer
  7 Scopus citations

• Photodynamic Therapy for the Treatment of Glioblastoma

  Cramer, S. W. & Chen, C. C., Jan 21 2020, In: Frontiers in Surgery. 6

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Scopus citations

• PI3K-GAMMA INHIBITION SUPPRESSES ACCUMULATION OF GLIOBLASTOMA-ASSOCIATED MICROGLIA TO RECAPITULATE THE MICROENVIRONMENT OF EXCEPTIONAL RESPONDERS

  Li, J., Kaneda, M., Ma, J., Li, M., Patel, K., Koga, T., Sarver, A. L., Furnari, F., Xu, B., Dhawan, S., Ning, J., Zhu, H., Wu, A., You, G., Jiang, T., Venteicher, A. S., Glass, C. K., Varner, J. & Chen, C. C., Nov 2020, In: Neuro-Oncology. 22, Supplement_2

  Research output: Contribution to journal › Article › peer-review

• Plasma Biomarker for Post-concussive Syndrome: A Pilot Study Using an Alternating Current Electro-Kinetic Platform

  Lewis, J. M., Dhawan, S., Obirieze, A. C., Sarno, B., Akers, J., Heller, M. J. & Chen, C. C., Jul 14 2020, In: Frontiers in Neurology. 11, 685.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Post-Concussion Syndrome
  • Ubiquitin Thiolesterase
  • Traumatic Brain Injury
  • Glial Fibrillary Acidic Protein
  • Cell-Free Nucleic Acids
  2 Scopus citations

• Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas

  Ramakrishnan, V., Xu, B., Akers, J., Nguyen, T., Ma, J., Dhawan, S., Ning, J., Mao, Y., Hua, W., Kokkoli, E., Furnari, F., Carter, B. S. & Chen, C. C., May 2020, In: EBioMedicine. 55, 102736.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles
  • Somatomedins
  • Glioblastoma
  • MicroRNAs
  • Radiation
  6 Scopus citations

• Resective epilepsy surgery: assessment of randomized controlled trials

  Cramer, S. W., McGovern, R. A., Wang, S., Chen, C. C. & Park, M. C., 2020, (Accepted/In press) In: Neurosurgical Review.

  Research output: Contribution to journal › Review article › peer-review

  • Epilepsy
  • Randomized Controlled Trials
  • Seizures
  • Temporal Lobe Epilepsy
  • Drug Resistant Epilepsy
  1 Scopus citations

• Short-term outcome following surgery for rare brain tumor entities in adults: a Swedish nation-wide registry-based study and comparison with SEER database

  Bartek, J., Dhawan, S., Thurin, E., Alattar, A., Gulati, S., Rydenhag, B., Henriksson, R., Chen, C. C. & Jakola, A. S., Jun 1 2020, In: Journal of neuro-oncology. 148, 2, p. 281-290 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Primitive Neuroectodermal Tumors
  • Registries
  • Epidemiology
  • Databases
  • Subependymal Glioma

• Supplementing decompression with instrumented fusion for symptomatic lumbar spinal stenosis—a critical appraisal of available randomized controlled trials

  Leschke, J. M. & Chen, C. C., Jan 1 2020, (Accepted/In press) In: Neurosurgical Review.

  Research output: Contribution to journal › Review article › peer-review

  • Spinal Stenosis
  • Decompression
  • Randomized Controlled Trials
  • Patient Selection
  • Spondylolisthesis
  3 Scopus citations

• Surgical management of spontaneous intracerebral hemorrhage: insights from randomized controlled trials

  Rennert, R. C., Tringale, K., Steinberg, J. A., Warnke, P., Konety, I., Sand, L. A., Karanjia, N., Tummala, R. & Chen, C. C., Jun 1 2020, In: Neurosurgical Review. 43, 3, p. 999-1006 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cerebral Hemorrhage
  • Randomized Controlled Trials
  • Mortality
  • Morbidity
  • Nervous System
  1 Scopus citations

• Survival association and cell cycle effects of B7H3 in neuroblastoma

  Zhang, H., Zhang, J., Li, C., Xu, H., Dong, R., Chen, C. C. & Hua, W., Nov 2020, In: Journal of Korean Neurosurgical Society. 63, 6, p. 707-716 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuroblastoma
  • Cell Cycle
  • Survival
  • Datasets
  • Staining and Labeling

• Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin α_vβ₅ Axis

  Zhu, Z., Mesci, P., Bernatchez, J. A., Gimple, R. C., Wang, X., Schafer, S. T., Wettersten, H. I., Beck, S., Clark, A. E., Wu, Q., Prager, B. C., Kim, L. J. Y., Dhanwani, R., Sharma, S., Garancher, A., Weis, S. M., Mack, S. C., Negraes, P. D., Trujillo, C. A., Penalva, L. O. & 14 others, Feng, J., Lan, Z., Zhang, R., Wessel, A. W., Dhawan, S., Diamond, M. S., Chen, C. C., Wechsler-Reya, R. J., Gage, F. H., Hu, H., Siqueira-Neto, J. L., Muotri, A. R., Cheresh, D. A. & Rich, J. N., Feb 6 2020, In: Cell Stem Cell. 26, 2, p. 187-204.e10

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Glioblastoma
  • Integrins
  • Stem Cells
  20 Scopus citations