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• 2020

  Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells (Nature Communications, (2020), 11, 1, (550), 10.1038/s41467-020-14312-1)

  Koga, T., Chaim, I. A., Benitez, J. A., Markmiller, S., Parisian, A. D., Hevner, R. F., Turner, K. M., Hessenauer, F. M., D’Antonio, M., Nguyen, N. P. D., Saberi, S., Ma, J., Miki, S., Boyer, A. D., Ravits, J., Frazer, K. A., Bafna, V., Chen, C. C., Mischel, P. S., Yeo, G. W. & 1 others, Furnari, F. B., Dec 1 2020, In: Nature communications. 11, 1, 1958.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • stem cells
  • Pluripotent Stem Cells
  • Tumors
  • tumors
  • cancer

• Cost-effectiveness of stereotactic laser ablation (SLA) for brain tumors

  Dhawan, S., Bartek, J. & Chen, C. C., Jul 15 2020, In: International Journal of Hyperthermia. 37, 2, p. 61-67 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Laser Therapy
  • Cost-Benefit Analysis
  • Craniotomy
  • Lasers
  • Hot Temperature
  1 Scopus citations

• Devascularization of a Hemorrhagic Pineocytoma by Laser Thermal Ablation Followed by Endoscopic Resection: A Proof-of-Principle Case Report

  Freeman, D., Guillaume, D., Bell, W. R. & Chen, C. C., Jul 2020, In: World neurosurgery. 139, p. 583-587 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Pinealoma
  • Laser Therapy
  • Hot Temperature
  • Surgical Hemostasis
  • Stereotaxic Techniques

• Early versus delayed postoperative radiotherapy for treatment of low-grade gliomas

  Dhawan, S., Patil, C. G., Chen, C. & Venteicher, A. S., Jan 20 2020, In: Cochrane Database of Systematic Reviews. 2020, 1, CD009229.

  Research output: Contribution to journal › Article › peer-review

  • Glioma
  • Radiotherapy
  • Therapeutics
  • Headache
  • Radiation
  10 Scopus citations

• Effect of Vocimagene Amiretrorepvec in Combination with Flucytosine vs Standard of Care on Survival following Tumor Resection in Patients with Recurrent High-Grade Glioma: A Randomized Clinical Trial

  Cloughesy, T. F., Petrecca, K., Walbert, T., Butowski, N., Salacz, M., Perry, J., Damek, D., Bota, D., Bettegowda, C., Zhu, J. J., Iwamoto, F., Placantonakis, D., Kim, L., Elder, B., Kaptain, G., Cachia, D., Moshel, Y., Brem, S., Piccioni, D., Landolfi, J. & 10 others, Chen, C. C., Gruber, H., Rao, A. R., Hogan, D., Accomando, W., Ostertag, D., Montellano, T. T., Kheoh, T., Kabbinavar, F. & Vogelbaum, M. A., Dec 2020, In: JAMA Oncology. 6, 12, p. 1939-1946 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Flucytosine
  • Standard of Care
  • Glioma
  • Randomized Controlled Trials
  • Survival
  3 Scopus citations

• Epidermal Growth Factor Receptor (EGFR) as a molecular determinant of glioblastoma response to dopamine receptor 2 (DRD2) inhibitors.

  He, Y., Li, J., Koga, T., Ma, J., Dhawan, S., Suzuki, Y., Furnari, F., Prabhu, V. V., Allen, J. & Chen, C. C., Aug 2020, In: Neuro-Oncology.

  Research output: Contribution to journal › Article › peer-review

• Epidermal growth factor receptor expression as a molecular determinant of glioblastoma response to the dopamine receptor D2 antagonist.

  He, Y., Ma, J., Dhawan, S., Koga, T., Furnari, F., Prabhu, V. V., Allen, J. & Chen, C. C., 2020.

  Research output: Contribution to conference › Poster

  • Dopamine D2 Receptor Antagonists
  • Glioblastoma
  • ErbB Receptors

• Frame-Based Stereotactic Endoscopic Third Ventriculostomy—Toward Improved Precision and Minimizing Morbidities

  Chen, C. C., Freeman, D. & Warnke, P. C., Aug 2020, In: World neurosurgery. 140, p. e240-e246

  Research output: Contribution to journal › Article › peer-review

  • Ventriculostomy
  • Anatomy
  • Morbidity
  • Stereotaxic Techniques
  • Third Ventricle

• GammaTile^®: Surgically targeted radiation therapy for glioblastomas

  Gessler, D. J., Ferreira, C., Dusenbery, K. & Chen, C. C., Oct 2020, In: Future Oncology. 16, 30, p. 2445-2455 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Glioblastoma
  • Radiation
  • Brachytherapy
  • Radiotherapy
  • Seeds
  3 Scopus citations

• GBP2 enhances glioblastoma invasion through Stat3/fibronectin pathway

  Yu, S., Yu, X., Sun, L., Zheng, Y., Chen, L., Xu, H., Jin, J., Lan, Q., Chen, C. C. & Li, M., Jul 2 2020, In: Oncogene. 39, 27, p. 5042-5055 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Glioblastoma
  • Fibronectins
  • Carrier Proteins
  • GTP Phosphohydrolases
  • Tumor Cell Line
  1 Scopus citations

• Genome engineering evolves brain tumor modeling

  Koga, T., Chen, C. C. & Furnari, F. B., 2020, In: Neurologia Medico-Chirurgica. 60, 7, p. 329-336 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome
  • Mutation
  • Glioblastoma
  • Neoplasms
  • Typical Teratoid Rhabdoid Tumor
  1 Scopus citations

• Glioblastomas located in proximity to the subventricular zone (SVZ) exhibited enrichment of gene expression profiles associated with the cancer stem cell state

  Steed, T. C., Treiber, J. M., Taha, B., Engin, H. B., Carter, H., Patel, K. S., Dale, A. M., Carter, B. S. & Chen, C. C., Jul 1 2020, In: Journal of neuro-oncology. 148, 3, p. 455-462 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lateral Ventricles
  • Neoplastic Stem Cells
  • Glioblastoma
  • Transcriptome
  • Stem Cells
  2 Scopus citations

• Hemorrhagic Complications of Invasive Intracranial Pressure Monitor Placement in Acute Liver Failure: Outcomes of a Single-Center Protocol and Comprehensive Literature Review

  Jinadasa, S. P., Ruan, Q. Z., Bayoumi, A. B., Sharma, S. V., Boone, M. D., Malik, R., Chen, C. C. & Kasper, E. M., 2020, (Accepted/In press) In: Neurocritical Care.

  Research output: Contribution to journal › Article › peer-review

  • Acute Liver Failure
  • Hemorrhage
  • Intracranial Hypertension
  • Brain Edema
  • Chronology

• Laser ablation of abnormal neurological tissue using robotic neuroblate system (laantern): 12-month outcomes and quality of life after brain tumor ablation

  Kim, A. H., Tatter, S., Rao, G., Prabhu, S., Chen, C., Fecci, P., Chiang, V., Smith, K., Williams, B. J., Mohammadi, A. M., Judy, K., Sloan, A., Tovar-Spinoza, Z., Baumgartner, J., Hadjipanayis, C. & Leuthardt, E. C., Sep 1 2020, In: Neurosurgery. 87, 3, p. E338-E346

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Laser Therapy
  • Robotics
  • Quality of Life
  • Lasers
  • Registries
  4 Scopus citations

• Laser ablation of abnormal neurological tissue using robotic neuroblate system (laantern): Procedural safety and hospitalization

  Rennert, R. C., Khan, U., Bartek, J., Tatter, S. B., Field, M., Toyota, B., Fecci, P. E., Judy, K., Mohammadi, A. M., Landazuri, P., Sloan, A. E., Kim, A. H., Leuthardt, E. C. & Chen, C. C., Apr 1 2020, In: Neurosurgery. 86, 4, p. 538-547 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Laser Therapy
  • Robotics
  • Hospitalization
  • Safety
  • Intensive Care Units
  8 Scopus citations

• Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

  Koga, T., Chaim, I. A., Benitez, J. A., Markmiller, S., Parisian, A. D., Hevner, R. F., Turner, K. M., Hessenauer, F. M., D’Antonio, M., Nguyen, N. P. D., Saberi, S., Ma, J., Miki, S., Boyer, A. D., Ravits, J., Frazer, K. A., Bafna, V., Chen, C. C., Mischel, P. S., Yeo, G. W. & 1 others, Furnari, F. B., Dec 1 2020, In: Nature communications. 11, 1, 550.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • stem cells
  • Pluripotent Stem Cells
  • Tumors
  • tumors
  • cancer
  5 Scopus citations

• Photodynamic Therapy for the Treatment of Glioblastoma

  Cramer, S. W. & Chen, C. C., Jan 21 2020, In: Frontiers in Surgery. 6

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• PI3K-GAMMA INHIBITION SUPPRESSES ACCUMULATION OF GLIOBLASTOMA-ASSOCIATED MICROGLIA TO RECAPITULATE THE MICROENVIRONMENT OF EXCEPTIONAL RESPONDERS

  Li, J., Kaneda, M., Ma, J., Li, M., Patel, K., Koga, T., Sarver, A. L., Furnari, F., Xu, B., Dhawan, S., Ning, J., Zhu, H., Wu, A., You, G., Jiang, T., Venteicher, A. S., Glass, C. K., Varner, J. & Chen, C. C., Nov 2020, In: Neuro-Oncology. 22, Supplement_2

  Research output: Contribution to journal › Article › peer-review

• Plasma Biomarker for Post-concussive Syndrome: A Pilot Study Using an Alternating Current Electro-Kinetic Platform

  Lewis, J. M., Dhawan, S., Obirieze, A. C., Sarno, B., Akers, J., Heller, M. J. & Chen, C. C., Jul 14 2020, In: Frontiers in Neurology. 11, 685.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Post-Concussion Syndrome
  • Ubiquitin Thiolesterase
  • Traumatic Brain Injury
  • Glial Fibrillary Acidic Protein
  • Cell-Free Nucleic Acids
  2 Scopus citations

• Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas

  Ramakrishnan, V., Xu, B., Akers, J., Nguyen, T., Ma, J., Dhawan, S., Ning, J., Mao, Y., Hua, W., Kokkoli, E., Furnari, F., Carter, B. S. & Chen, C. C., May 2020, In: EBioMedicine. 55, 102736.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles
  • Somatomedins
  • Glioblastoma
  • MicroRNAs
  • Radiation
  4 Scopus citations

• Resective epilepsy surgery: assessment of randomized controlled trials

  Cramer, S. W., McGovern, R. A., Wang, S., Chen, C. C. & Park, M. C., 2020, (Accepted/In press) In: Neurosurgical Review.

  Research output: Contribution to journal › Review article › peer-review

  • Epilepsy
  • Randomized Controlled Trials
  • Seizures
  • Temporal Lobe Epilepsy
  • Drug Resistant Epilepsy

• Short-term outcome following surgery for rare brain tumor entities in adults: a Swedish nation-wide registry-based study and comparison with SEER database

  Bartek, J., Dhawan, S., Thurin, E., Alattar, A., Gulati, S., Rydenhag, B., Henriksson, R., Chen, C. C. & Jakola, A. S., Jun 1 2020, In: Journal of neuro-oncology. 148, 2, p. 281-290 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Primitive Neuroectodermal Tumors
  • Registries
  • Epidemiology
  • Databases
  • Subependymal Glioma

• Supplementing decompression with instrumented fusion for symptomatic lumbar spinal stenosis—a critical appraisal of available randomized controlled trials

  Leschke, J. M. & Chen, C. C., Jan 1 2020, (Accepted/In press) In: Neurosurgical Review.

  Research output: Contribution to journal › Review article › peer-review

  • Spinal Stenosis
  • Decompression
  • Randomized Controlled Trials
  • Patient Selection
  • Spondylolisthesis
  3 Scopus citations

• Surgical management of spontaneous intracerebral hemorrhage: insights from randomized controlled trials

  Rennert, R. C., Tringale, K., Steinberg, J. A., Warnke, P., Konety, I., Sand, L. A., Karanjia, N., Tummala, R. & Chen, C. C., Jun 1 2020, In: Neurosurgical Review. 43, 3, p. 999-1006 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cerebral Hemorrhage
  • Randomized Controlled Trials
  • Mortality
  • Morbidity
  • Nervous System
  1 Scopus citations

• Survival association and cell cycle effects of B7H3 in neuroblastoma

  Zhang, H., Zhang, J., Li, C., Xu, H., Dong, R., Chen, C. C. & Hua, W., Nov 2020, In: Journal of Korean Neurosurgical Society. 63, 6, p. 707-716 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuroblastoma
  • Cell Cycle
  • Survival
  • Datasets
  • Staining and Labeling

• Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin α_vβ₅ Axis

  Zhu, Z., Mesci, P., Bernatchez, J. A., Gimple, R. C., Wang, X., Schafer, S. T., Wettersten, H. I., Beck, S., Clark, A. E., Wu, Q., Prager, B. C., Kim, L. J. Y., Dhanwani, R., Sharma, S., Garancher, A., Weis, S. M., Mack, S. C., Negraes, P. D., Trujillo, C. A., Penalva, L. O. & 14 others, Feng, J., Lan, Z., Zhang, R., Wessel, A. W., Dhawan, S., Diamond, M. S., Chen, C. C., Wechsler-Reya, R. J., Gage, F. H., Hu, H., Siqueira-Neto, J. L., Muotri, A. R., Cheresh, D. A. & Rich, J. N., Feb 6 2020, In: Cell Stem Cell. 26, 2, p. 187-204.e10

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Glioblastoma
  • Integrins
  • Stem Cells
  14 Scopus citations
• 2019

  A Pilot Proof-Of-Principle Analysis Demonstrating Dielectrophoresis (DEP) as a Glioblastoma Biomarker Platform

  Lewis, J., Alattar, A. A., Akers, J., Carter, B. S., Heller, M. & Chen, C. C., Dec 1 2019, In: Scientific reports. 9, 1, 10279.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles
  • Glioblastoma
  • Biomarkers
  • Glial Fibrillary Acidic Protein
  • Fluorescent Antibody Technique
  7 Scopus citations

• Association between medical academic genealogy and publication outcome: impact of unconscious bias on scientific objectivity

  Hirshman, B. R., Alattar, A. A., Dhawan, S., Carley, K. M. & Chen, C. C., Feb 13 2019, In: Acta Neurochirurgica. 161, 2, p. 205-211 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Publications
  • Meta-Analysis
  • Odds Ratio
  • Glioblastoma
  • Astrocytoma
  1 Scopus citations

• B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma

  Zhang, J., Wang, J., Marzese, D. M., Wang, X., Yang, Z., Li, C., Zhang, H., Zhang, J., Chen, C. C., Kelly, D. F., Hua, W., Hoon, D. S. B. & Mao, Y., Jul 1 2019, In: Laboratory Investigation. 99, 8, p. 1117-1129 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Theranostic Nanomedicine
  • Glioblastoma
  • Biomarkers
  • RNA Sequence Analysis
  • Down-Regulation
  6 Scopus citations

• Biopsy and Ablation of H3K27 Glioma Using Skull-Mounted Smartframe Device: Technical Case Report

  Bartek, J., Alattar, A., Jensdottir, M. & Chen, C. C., Jul 2019, In: World neurosurgery. 127, p. 436-441 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Skull
  • Glioma
  • Biopsy
  • Equipment and Supplies
  • Ventriculoperitoneal Shunt
  2 Scopus citations

• Clinical course in chronic subdural hematoma patients aged 18–49 compared to patients 50 years and above: A multicenter study and meta-analysis

  Bartek, J., Sjåvik, K., Dhawan, S., Sagberg, L. M., Kristiansson, H., Ståhl, F., Förander, P., Chen, C. C. & Jakola, A. S., 2019, In: Frontiers in Neurology. 10, APR, 311.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hematoma, Subdural, Chronic
  • Multicenter Studies
  • Meta-Analysis
  • Recurrence
  • Headache
  3 Scopus citations

• Comparison of Frame-Based Versus Frameless Intracranial Stereotactic Biopsy: Systematic Review and Meta-Analysis

  Dhawan, S., He, Y., Bartek, J., Alattar, A. A. & Chen, C. C., Jul 2019, In: World neurosurgery. 127, p. 607-616.e4

  Research output: Contribution to journal › Review article › peer-review

  • Meta-Analysis
  • Systematic Reviews
  • Biopsy
  • Confidence Intervals
  • Odds Ratio
  13 Scopus citations

• Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Prophylactic Anticonvulsants in the Treatment of Adults with Metastatic Brain Tumors

  Chen, C. C., Rennert, R. C. & Olson, J. J., Mar 1 2019, In: Clinical Neurosurgery. 84, 3, p. E195-E197

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Neurosurgeons
  • Anticonvulsants
  • Seizures
  • Systematic Reviews
  • Guidelines
  26 Scopus citations

• Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on Treatment Options for Adults with Multiple Metastatic Brain Tumors

  Ammirati, M., Nahed, B. V., Andrews, D., Chen, C. C. & Olson, J. J., Mar 1 2019, In: Clinical Neurosurgery. 84, 3, p. E180-E182

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Neurosurgeons
  • Systematic Reviews
  • Guidelines
  • Radiosurgery
  • Brain
  26 Scopus citations

• Development of a Novel Canine Model of Ischemic Stroke: Skull Base Approach with Transient Middle Cerebral Artery Occlusion

  Vasquez, C. A., Moen, S. L., Juliano, M. J., Jagadeesan, B. D., Pluhar, G. E., Chen, C. C. & Grande, A. W., Jul 2019, In: World neurosurgery. 127, p. e251-e260

  Research output: Contribution to journal › Article › peer-review

  • Ophthalmic Artery
  • Middle Cerebral Artery Infarction
  • Anterior Cerebral Artery
  • Skull Base
  • Middle Cerebral Artery

• Erratum: Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair (Cancer Cell (2019) 35(3) (504–518.e7), (S1535610819300546), (10.1016/j.ccell.2019.01.020))

  Ma, J., Benitez, J. A., Li, J., Miki, S., Ponte de Albuquerque, C., Galatro, T., Orellana, L., Zanca, C., Reed, R., Boyer, A., Koga, T., Varki, N. M., Fenton, T. R., Nagahashi Marie, S. K., Lindahl, E., Gahman, T. C., Shiau, A. K., Zhou, H., DeGroot, J., Sulman, E. P. & 4 others, Cavenee, W. K., Kolodner, R. D., Chen, C. C. & Furnari, F. B., Dec 9 2019, In: Cancer Cell. 36, 6, p. 690-691 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Radiation Tolerance
  • Glioma
  • Tyrosine
  • Phosphorylation
  • Control Groups
  3 Scopus citations

• Erratum: Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair (Cancer Cell (2019)35(3)(504–518.e7), (S1535610819300546), (10.1016/j.ccell.2019.01.020))

  Ma, J., Benitez, J. A., Li, J., Miki, S., Ponte de Albuquerque, C., Galatro, T., Orellana, L., Zanca, C., Reed, R., Boyer, A., Koga, T., Varki, N. M., Fenton, T. R., Nagahashi Marie, S. K., Lindahl, E., Gahman, T. C., Shiau, A. K., Zhou, H., DeGroot, J., Sulman, E. P. & 4 others, Cavenee, W. K., Kolodner, R. D., Chen, C. C. & Furnari, F. B., May 13 2019, In: Cancer Cell. 35, 5, p. 816 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Radiation Tolerance
  • Glioma
  • Tyrosine
  • Radiation
  • Phosphorylation
  10 Scopus citations

• Extracellular vesicles as carriers of suicide mRNA and/or protein in cancer therapy

  Erkan, E. P., Saydam, N., Chen, C. C. & Saydam, O., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 87-96 10 p. (Methods in Molecular Biology; vol. 1895).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Extracellular Vesicles
  • Suicide
  • Genetic Therapy
  • Messenger RNA
  • Prodrugs
  1 Scopus citations

• Infratentorial Glioblastoma Metastasis to Bone

  Ricard, J. A., Cramer, S. W., Charles, R., Gil Tommee, C., Le, A., Bell, W. R., Chen, C. C. & Flanagan, M. E., Nov 2019, In: World neurosurgery. 131, p. 90-94 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Glioblastoma
  • Neoplasm Metastasis
  • Spine
  • Primitive Neuroectodermal Tumors
  • Neuroglia
  2 Scopus citations

• Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair

  Ma, J., Benitez, J. A., Li, J., Miki, S., Ponte de Albuquerque, C., Galatro, T., Orellana, L., Zanca, C., Reed, R., Boyer, A., Koga, T., Varki, N. M., Fenton, T. R., Nagahashi Marie, S. K., Lindahl, E., Gahman, T. C., Shiau, A. K., Zhou, H., DeGroot, J., Sulman, E. P. & 4 others, Cavenee, W. K., Kolodner, R. D., Chen, C. C. & Furnari, F. B., Mar 18 2019, In: Cancer Cell. 35, 3, p. 504-518.e7

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Radiation Tolerance
  • Ionizing Radiation
  • Glioblastoma
  • Glioma
  • Tyrosine
  23 Scopus citations

• Machine Learning Based Real-Time Image-Guided Cell Sorting and Classification

  Gu, Y., Zhang, A. C., Han, Y., Li, J., Chen, C. C. & Lo, Y. H., May 2019, In: Cytometry Part A. 95, 5, p. 499-509 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Machine Learning
  • Technology
  • Microscopy
  • Optics and Photonics
  • Microfluidics
  15 Scopus citations

• Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma

  Chahal, K. K., Li, J., Kufareva, I., Parle, M., Durden, D. L., Wechsler-Reya, R. J., Chen, C. C. & Abagyan, R., Sep 1 2019, In: PloS one. 14, 9, e0214901.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide
  • Hedgehogs
  • Erinaceidae
  • Medulloblastoma
  • leukemia
  1 Scopus citations

• Prognostic Importance of Age, Tumor Location, and Tumor Grade in Grade II Astrocytomas: An Integrated Analysis of the Cancer Genome Atlas and the Surveillance, Epidemiology, and End Results Database

  Alattar, A. A., Carroll, K. T., Bryant, A. K., Hirshman, B., Joshi, R., Carter, B. S., Harismendy, O. & Chen, C. C., Jan 2019, In: World neurosurgery. 121, p. e411-e418

  Research output: Contribution to journal › Article › peer-review

  • Astrocytoma
  • Atlases
  • Epidemiology
  • Genome
  • Databases
  4 Scopus citations

• Prognostic Importance of Cumulative Intracranial Tumor Volume in Patients with Gastrointestinal Brain Metastasis Treated with Stereotactic Radiosurgery

  Joshi, R. S., Hirshman, B. R., Ali, M. A., Alattar, A., Carroll, K., Nagano, O., Aiyama, H., Serizawa, T., Yamamoto, M. & Chen, C. C., Jan 2019, In: World neurosurgery. 121, p. e747-e754

  Research output: Contribution to journal › Article › peer-review

  • Radiosurgery
  • Tumor Burden
  • Neoplasm Metastasis
  • Brain
  • Logistic Models
  4 Scopus citations

• Receipt of brachytherapy is an independent predictor of survival in glioblastoma in the Surveillance, Epidemiology, and End Results database

  Bartek, J., Alattar, A. A., Dhawan, S., Ma, J., Koga, T., Nakaji, P., Dusenbery, K. E. & Chen, C. C., Oct 2019, In: Journal of neuro-oncology. 145, 1, p. 75-83 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Brachytherapy
  • Glioblastoma
  • Epidemiology
  • Databases
  • Survival
  3 Scopus citations

• Smoking As a Risk Factor for Postcraniotomy 30-Day Mortality

  Lochte, B. C., Carroll, K. T., Hirshman, B., Lanman, T., Carter, B. & Chen, C. C., Jul 2019, In: World neurosurgery. 127, p. e400-e406

  Research output: Contribution to journal › Article › peer-review

  • Smoking
  • Craniotomy
  • Mortality
  • Quality Improvement
  • Surgeons
  1 Scopus citations

• Stereotactic Laser Ablation as Treatment of Brain Metastases Recurring after Stereotactic Radiosurgery: A Systematic Literature Review

  Alattar, A. A., Bartek, J., Chiang, V. L., Mohammadi, A. M., Barnett, G. H., Sloan, A. & Chen, C. C., Aug 2019, In: World neurosurgery. 128, p. 134-142 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Radiosurgery
  • Laser Therapy
  • Systematic Reviews
  • Neoplasm Metastasis
  • Brain
  10 Scopus citations

• The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research

  The Extracellular RNA Communication Consortium, Apr 4 2019, In: Cell. 177, 2, p. 231-242 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • RNA
  • Technology
  • Communication
  • Extracellular Vesicles
  • Biomarkers
  45 Scopus citations

• Treatment combining CD200 immune checkpoint inhibitor and tumor-lysate vaccination after surgery for pet dogs with high-grade glioma

  Olin, M. R., Ampudia-Mesias, E., Pennell, C. A., Sarver, A., Chen, C. C., Moertel, C. L., Hunt, M. A. & Pluhar, G. E., Jan 1 2019, In: Cancers. 11, 2, 137.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pets
  • Glioma
  • Vaccination
  • Dogs
  • Antigen-Presenting Cells
  8 Scopus citations

• Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

  Rosato, P. C., Wijeyesinghe, S., Stolley, J. M., Nelson, C. E., Davis, R. L., Manlove, L. S., Pennell, C. A., Blazar, B. R., Chen, C. C., Geller, M. A., Vezys, V. & Masopust, D., Dec 1 2019, In: Nature communications. 10, 1, 567.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • T-cells
  • Viruses
  • Tumors
  • tumors
  • Immunotherapy
  43 Scopus citations