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  • Jim Pankow
2018

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article

ExomeBP Consortium, MAGIC Consortium & GIANT Consortium, Apr 1 2018, In : Nature Genetics. 50, 4, p. 559-571 13 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations
Open Access
6 Scopus citations

Short-Term Repeatability of Insulin Resistance Indexes in Older Adults: The Atherosclerosis Risk in Communities Study

Poon, A. K., Meyer, M. L., Reaven, G., Knowles, J. W., Selvin, E., Pankow, J. S., Couper, D., Loehr, L. & Heiss, G., Jun 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 6, p. 2175-2181 7 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2017

ABO blood group is associated with peripheral arterial disease in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA)

Pike, M. M., Larson, N. B., Wassel, C. L., Cohoon, K. P., Tsai, M. Y., Pankow, J. S., Hanson, N. Q., Decker, P. A., Berardi, C., Alexander, K. S., Cushman, M., Zakai, N. A. & Bielinski, S. J., May 1 2017, In : Thrombosis Research. 153, p. 1-6 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 31 others, Almgren, P., Voight, B. F., Grallert, H., Müller-Nurasyid, M., Ried, J. S., Rayner, N. W., Robertson, N., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Sparso, T., Kestler, H. A., Chheda, H., Eisele, L., Gustafsson, S., Frånberg, M., Strawbridge, R. J., Benediktsson, R., Hreidarsson, A. B., Pankow, J. S. & DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Nov 1 2017, In : Diabetes. 66, 11, p. 2888-2902 15 p.

Research output: Contribution to journalArticle

Open Access
195 Scopus citations

A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women

Haddad, S. A., Palmer, J. R., Lunetta, K. L., Ng, M. C. Y., Ruiz-Narváez, E. A., Shriner, D., Chen, B. H., Li, J., Chen, W. M., Guo, X., Liu, J., Bielinski, S. J., Yanek, L. R., Nalls, M. A., Comeau, M. E., Rasmussen-Torvik, L. J., Jensen, R. A., Evans, D. S., Sun, Y. V., An, P. & 31 others, Patel, S. R., Lu, Y., Long, J., Armstrong, L. L., Wagenknecht, L., Yang, L., Snively, B. M., Palmer, N. D., Mudgal, P., Langefeld, C. D., Keene, K. L., Freedman, B. I., Mychaleckyj, J. C., Nayak, U., Raffel, L. J., Goodarzi, M. O., Chen, Y. D. I., Taylor, H. A., Correa, A., Sims, M., Couper, D., Pankow, J. S., Boerwinkle, E., Adeyemo, A., Doumatey, A., Chen, G., Mathias, R. A., Vaidya, D., Singleton, A. B., Zonderman, A. B. & MEDIA Consortium, Mar 1 2017, In : PloS one. 12, 3, e0172577.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Association between high-sensitivity troponin T and cardiovascular risk in individuals with and without metabolic syndrome: The ARIC study

Pokharel, Y., Sun, W., Villareal, D. T., Selvin, E., Virani, S. S., Ndumele, C. E., Hoogeveen, R. C., Coresh, J., Boerwinkle, E., Butler, K. R., Solomon, S. D., Pankow, J. S., Bozkurt, B., Ballantyne, C. M. & Nambi, V., Jan 1 2017, In : European Journal of Preventive Cardiology. 24, 6, p. 628-638 11 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

Mendelson, M. M., Marioni, R. E., Joehanes, R., Liu, C., Hedman, Å. K., Aslibekyan, S., Demerath, E. W., Guan, W., Zhi, D., Yao, C., Huan, T., Willinger, C., Chen, B., Courchesne, P., Multhaup, M., Irvin, M. R., Cohain, A., Schadt, E. E., Grove, M. L., Bressler, J. & 29 others, North, K., Sundström, J., Gustafsson, S., Shah, S., McRae, A. F., Harris, S. E., Gibson, J., Redmond, P., Corley, J., Murphy, L., Starr, J. M., Kleinbrink, E., Lipovich, L., Visscher, P. M., Wray, N. R., Krauss, R. M., Fallin, D., Feinberg, A., Absher, D. M., Fornage, M., Pankow, J. S., Lind, L., Fox, C., Ingelsson, E., Arnett, D. K., Boerwinkle, E., Liang, L., Levy, D. & Deary, I. J., Jan 2017, In : PLoS Medicine. 14, 1, e1002215.

Research output: Contribution to journalArticle

Open Access
85 Scopus citations

Brain function and structure and risk for incident diabetes: The Atherosclerosis Risk in Communities Study

Bancks, M. P., Alonso, A., Gottesman, R. F., Mosley, T. H., Selvin, E. & Pankow, J. S., Dec 2017, In : Alzheimer's and Dementia. 13, 12, p. 1345-1354 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study

Raina, A., Zhao, X., Grove, M. L., Bressler, J., Gottesman, R. F., Guan, W., Pankow, J. S., Boerwinkle, E., Mosley, T. H. & Fornage, M., Feb 14 2017, In : Clinical epigenetics. 9, 1, 21.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Coffee consumption and calcified atherosclerotic plaques in the coronary arteries: The NHLBI Family Heart Study

Patel, Y. R., Gadiraju, T. V., Ellison, R. C., Hunt, S. C., Carr, J. J., Heiss, G., Arnett, D. K., Pankow, J. S., Gaziano, J. M. & Djoussé, L., Feb 1 2017, In : Clinical Nutrition ESPEN. 17, p. 18-21 4 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Comparative prognostic performance of definitions of prediabetes: a prospective cohort analysis of the Atherosclerosis Risk in Communities (ARIC) study

Warren, B., Pankow, J. S., Matsushita, K., Punjabi, N. M., Daya, N. R., Grams, M., Woodward, M. & Selvin, E., Jan 1 2017, In : The Lancet Diabetes and Endocrinology. 5, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations

Correction to: Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium (Diabetologia, 10.1007/s00125-017-4405-1)

Bien, S. A., Pankow, J. S., Haessler, J., Lu, Y., Pankratz, N., Rohde, R. R., Tamuno, A., Carlson, C. S., Schumacher, F. R., Bůžková, P., Daviglus, M. L., Lim, U., Fornage, M., Fernandez-Rhodes, L., Avilés-Santa, L., Buyske, S., Gross, M. D., Graff, M., Isasi, C. R., Kuller, L. H. & 12 others, Manson, J. A. E., Matise, T. C., Prentice, R. L., Wilkens, L. R., Yoneyama, S., Loos, R. J. F., Hindorff, L. A., Le Marchand, L., North, K. E., Haiman, C. A., Peters, U. & Kooperberg, C., Dec 1 2017, In : Diabetologia. 60, 12, p. 2542-2543 2 p.

Research output: Contribution to journalComment/debate

Open Access

Detection of genetic loci associated with plasma fetuin-A: A meta-analysis of genome-wide association studies from the CHARGE Consortium

Jensen, M. K., Jensen, R. A., Mukamal, K. J., Guo, X., Yao, J., Sun, Q., Cornelis, M., Liu, Y., Chen, M. H., Kizer, J. R., Djoussé, L., Siscovick, D. S., Psaty, B. M., Zmuda, J. M., Rotter, J. I., Garcia, M., Harris, T., Chen, I., Goodarzi, M. O., Nalls, M. A. & 11 others, Keller, M., Arnold, A. M., Newman, A. B., Hoogeveen, R. C., Rexrode, K. M., Rimm, E. B., Hu, F. B., Ramachandran, V. S., Katz, R., Pankow, J. S. & Ix, J. H., Jan 1 2017, In : Human molecular genetics. 26, 11, p. 2156-2163 8 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Diabetes, hyperglycemia, and the burden of functional disability among older adults in a community-based study:

Godino, J. G., Appel, L. J., Gross, A. L., Schrack, J. A., Parrinello, C. M., Kalyani, R. R., Windham, B. G., Pankow, J. S., Kritchevsky, S. B., Bandeen-Roche, K. & Selvin, E., Jan 1 2017, In : Journal of Diabetes. 9, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Dichotic digits test performance across the ages: Results from two large epidemiologic cohort studies

Fischer, M. E., Cruickshanks, K. J., Nondahl, D. M., Klein, B. E. K., Klein, R., Pankow, J. S., Tweed, T. S., Dalton, D. S. & Paulsen, A. J., Jan 1 2017, In : Ear and hearing. 38, 3, p. 314-320 7 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Elevated Levels of Adhesion Proteins Are Associated with Low Ankle-Brachial Index: Multi-Ethnic Study of Atherosclerosis

Berardi, C., Wassel, C. L., Decker, P. A., Larson, N. B., Kirsch, P. S., Andrade, M. D., Tsai, M. Y., Pankow, J. S., Sale, M. M., Sicotte, H., Tang, W., Hanson, N. Q., McDermott, M. M., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2017, In : Angiology. 68, 4, p. 322-329 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Epigenome-wide association studies identify DNA methylation associated with kidney function

Chu, A. Y., Tin, A., Schlosser, P., Ko, Y. A., Qiu, C., Yao, C., Joehanes, R., Grams, M. E., Liang, L., Gluck, C. A., Liu, C., Coresh, J., Hwang, S. J., Levy, D., Boerwinkle, E., Pankow, J. S., Yang, Q., Fornage, M., Fox, C. S., Susztak, K. & 1 others, Köttgen, A., Dec 1 2017, In : Nature communications. 8, 1, 1286.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Experiences of discrimination and incident type 2 diabetes mellitus: The Multi-Ethnic Study of Atherosclerosis (MESA)

Whitaker, K. M., Everson-Rose, S. A., Pankow, J. S., Rodriguez, C. J., Lewis, T. T., Kershaw, K. N., Diez Roux, A. V. & Lutsey, P. L., Jan 1 2017, In : American journal of epidemiology. 186, 4, p. 445-455 11 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Ferritin levels and risk of heart failure—the Atherosclerosis Risk in Communities Study

Silvestre, O. M., Gonçalves, A., Nadruz, W., Claggett, B., Couper, D., Eckfeldt, J. H., Pankow, J. S., Anker, S. D. & Solomon, S. D., Mar 1 2017, In : European Journal of Heart Failure. 19, 3, p. 340-347 8 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations

Yoneyama, S., Yao, J., Guo, X., Fernandez-Rhodes, L., Lim, U., Boston, J., Buzková, P., Carlson, C. S., Cheng, I., Cochran, B., Cooper, R., Ehret, G., Fornage, M., Gong, J., Gross, M., Gu, C. C., Haessler, J., Haiman, C. A., Henderson, B., Hindorff, L. A. & 30 others, Houston, D., Irvin, M. R., Jackson, R., Kuller, L., Leppert, M., Lewis, C. E., Li, R., Le Marchand, L., Matise, T. C., Nguyen, K. D., Chakravarti, A., Pankow, J. S., Pankratz, N., Pooler, L., Ritchie, M. D., Bien, S. A., Wassel, C. L., Chen, Y. D., Taylor, K. D., Allison, M., Rotter, J. I., Schreiner, P. J., Schumacher, F., Wilkens, L., Boerwinkle, E., Kooperberg, C., Peters, U., Buyske, S., Graff, M. & North, K. E., Feb 1 2017, In : International Journal of Obesity. 41, 2, p. 324-331 8 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Genetics of type 2 diabetes in U.S. Hispanic/Latino individuals: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Qi, Q., Stilp, A. M., Sofer, T., Moon, J. Y., Hidalgo, B., Szpiro, A. A., Wang, T., Ng, M. C. Y., Guo, X., Chen, Y. D. I., Taylor, K. D., Aviles-Santa, M. L., Papanicolaou, G., Pankow, J. S., Schneiderman, N., Laurie, C. C., Rotter, J. I. & Kaplan, R. C., May 1 2017, In : Diabetes. 66, 5, p. 1419-1425 7 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Genetic variants associated with circulating parathyroid hormone

Robinson-Cohen, C., Lutsey, P. L., Kleber, M. E., Nielson, C. M., Mitchell, B. D., Bis, J. C., Eny, K. M., Portas, L., Eriksson, J., Lorentzon, M., Koller, D. L., Milaneschi, Y., Teumer, A., Pilz, S., Nethander, M., Selvin, E., Tang, W., Weng, L. C., Wong, H. S., Lai, D. & 29 others, Peacock, M., Hannemann, A., Völker, U., Homuth, G., Nauk, M., Murgia, F., Pattee, J. W., Orwoll, E., Zmuda, J. M., Riancho, J. A., Wolf, M., Williams, F., Penninx, B., Econs, M. J., Ryan, K. A., Ohlsson, C., Paterson, A. D., Psaty, B. M., Siscovick, D. S., Rotter, J. I., Pirastu, M., Streeten, E., März, W., Fox, C., Coresh, J., Wallaschofski, H., Pankow, J. S., De Boer, I. H. & Kestenbaum, B., May 2017, In : Journal of the American Society of Nephrology. 28, 5, p. 1553-1565 13 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism

Li, M., Maruthur, N. M., Loomis, S. J., Pietzner, M., North, K. E., Mei, H., Morrison, A. C., Friedrich, N., Pankow, J. S., Nauck, M., Boerwinkle, E., Teumer, A., Selvin, E. & Köttgen, A., Dec 1 2017, In : Scientific reports. 7, 1, 2812.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Genome-wide association test of multiple continuous traits using imputed SNPs

Wu, B. & Pankow, J. S., Jan 1 2017, In : Statistics and its Interface. 10, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genome-wide interaction with selected type 2 diabetes loci reveals novel loci for type 2 diabetes in african americans

Keaton, J. M., Hellwege, J. N., Ng, M. C. Y., Palmer, N. D., Pankow, J. S., Fornage, M., Wilson, J. G., Correa, A., Rasmussen-Torvik, L. J., Rotter, J. I., Chen, Y. D. E. R. I., Taylor, K. D., Rich, S. S., Wagenknecht, L. E., Freedman, B. I. & Bowden, D. W., Jan 1 2017, In : Pacific Symposium on Biocomputing. 0, 212679, p. 242-253 12 p.

Research output: Contribution to journalConference article

5 Scopus citations

Hepatocyte growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease

Bielinski, S. J., Berardi, C., Decker, P. A., Larson, N. B., Bell, E. J., Pankow, J. S., Sale, M. M., Tang, W., Hanson, N. Q., Wassel, C. L., De Andrade, M., Budoff, M. J., Polak, J. F., Sicotte, H. & Tsai, M. Y., Aug 1 2017, In : Heart. 103, 15, p. 1185-1193 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
Open Access
8 Scopus citations

Hospitalization with infection and incident venous thromboembolism: The ARIC study

Cowan, L. T., Lutsey, P. L., Pankow, J. S., Cushman, M. & Folsom, A. R., Mar 1 2017, In : Thrombosis Research. 151, p. 74-78 5 p.

Research output: Contribution to journalArticle

Open Access
Open Access
6 Scopus citations

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

Wheeler, E., Leong, A., Liu, C. T., Hivert, M. F., Strawbridge, R. J., Podmore, C., Li, M., Yao, J., Sim, X., Hong, J., Chu, A. Y., Zhang, W., Wang, X., Chen, P., Maruthur, N. M., Porneala, B. C., Sharp, S. J., Jia, Y., Kabagambe, E. K., Chang, L. C. & 33 others, Chen, W. M., Elks, C. E., Evans, D. S., Fan, Q., Giulianini, F., Go, M. J., Hottenga, J. J., Hu, Y., Jackson, A. U., Kanoni, S., Kim, Y. J., Kleber, M. E., Ladenvall, C., Lecoeur, C., Lim, S. H., Lu, Y., Mahajan, A., Marzi, C., Nalls, M. A., Navarro, P., Nolte, I. M., Rose, L. M., Rybin, D. V., Sanna, S., Shi, Y., Stram, D. O., Takeuchi, F., Pankow, J. S., Heng, C. K., Sabanayagam, C., EPIC-CVD Consortium, EPIC-InterAct Consortium & Lifelines Cohort Study, Sep 2017, In : PLoS Medicine. 14, 9, e1002383.

Research output: Contribution to journalArticle

Open Access
88 Scopus citations

Low high-density lipoprotein cholesterol and particle concentrations are associated with greater levels of endothelial activation markers in Multi-Ethnic Study of Atherosclerosis participants

Steffen, B. T., Bielinski, S. J., Decker, P. A., Berardi, C., Larson, N. B., Pankow, J. S., Michos, E. D., Hanson, N. Q., Herrington, D. M. & Tsai, M. Y., Jul 2017, In : Journal of Clinical Lipidology. 11, 4, p. 955-963.e3

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Quantifying the extent to which index event biases influence large genetic association studies

Yaghootkar, H., Bancks, M. P., Jones, S. E., McDaid, A., Beaumont, R., Donnelly, L., Wood, A. R., Campbell, A., Tyrrell, J., Hocking, L. J., Tuke, M. A., Ruth, K. S., Pearson, E. R., Murray, A., Freathy, R. M., Munroe, P. B., Hayward, C., Palmer, C., Weedon, M. N., Pankow, J. S. & 2 others, Frayling, T. M. & Kutalik, Z., Mar 1 2017, In : Human molecular genetics. 26, 5, p. 1003-1017 15 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis

Roetker, N. S., Armasu, S. M., Pankow, J. S., Lutsey, P. L., Tang, W., Rosenberg, M. A., Palmer, T. M., Maclehose, R. F., Heckbert, S. R., Cushman, M., de Andrade, M. & Folsom, A. R., Jul 2017, In : Journal of Thrombosis and Haemostasis. 15, 7, p. 1334-1343 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium

Bien, S. A., Pankow, J. S., Haessler, J., Lu, Y. N., Pankratz, N., Rohde, R. R., Tamuno, A., Carlson, C. S., Schumacher, F. R., Bůžková, P., Daviglus, M. L., Lim, U., Fornage, M., Fernandez-Rhodes, L., Avilés-Santa, L., Buyske, S., Gross, M. D., Graff, M., Isasi, C. R., Kuller, L. H. & 12 others, Manson, J. A. E., Matise, T. C., Prentice, R. L., Wilkens, L. R., Yoneyama, S., Loos, R. J. F., Hindorff, L. A., Le Marchand, L., North, K. E., Haiman, C. A., Peters, U. & Kooperberg, C., Dec 1 2017, In : Diabetologia. 60, 12, p. 2384-2398 15 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

Rusu, V., Rusu, V., Hoch, E., Mercader, J. M., Gymrek, M., von Grotthuss, M., Fontanillas, P., Spooner, A., Altshuler, D. M., Florez, J. C., Jacobs, S. B. R., Hoch, E., Clish, C. B., Florez, J. C., Jacobs, S. B. R., Mercader, J. M., Florez, J. C., Jacobs, S. B. R., Mercader, J. M., Tenen, D. E. & 51 others, Hartigan, C. R., DeRan, M., Guzman, G., Deik, A. A., Pierce, K. A., Dennis, C., Clish, C. B., Carr, S. A., Wagner, B. K., Schenone, M., Schreiber, S. L., Lander, E. S., Tenen, D. E., Gymrek, M., Ng, M. C. Y., Chen, B. H., Centeno-Cruz, F., Orozco, L., Zerrweck, C., Altshuler, D. M., Altshuler, D. M., Altshuler, D. M., Florez, J. C., Altshuler, D. M., Lander, E. S., Lander, E. S., Ng, M. C. Y., Shriner, D., Chen, B. H., Pankow, J. S., MEDIA Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the MuTHER Consortium, SIGMA T2D Consortium & SIGMA T2D Consortium, Jun 29 2017, In : Cell. 170, 1, p. 199-212.e20

Research output: Contribution to journalArticle

Open Access
53 Scopus citations
2016

ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Bell, E. J., Decker, P. A., Pike, M., Wassel, C. L., Tsai, M. Y., Pankow, J. S., Tang, W., Hanson, N. Q., Alexander, K., Zakai, N. A., Cushman, M. & Bielinski, S. J., Aug 1 2016, In : Atherosclerosis. 251, p. 422-429 8 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancáková, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., Van Der Lee, S. J. & 118 others, Gillson, C., Al Olama, A. A., Amouyel, P., Arriola, L., Arveiler, D., Aviles-Olmos, I., Balkau, B., Barricarte, A., Barroso, I., Garcia, S. B., Bis, J. C., Blankenberg, S., Boehnke, M., Boeing, H., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bowden, S., Caldas, C., Caslake, M., Cupples, L. A., Cruchaga, C., Czajkowski, J., Den Hoed, M., Dunn, J. A., Earl, H. M., Ehret, G. B., Ferrannini, E., Ferrieres, J., Foltynie, T., Ford, I., Forouhi, N. G., Gianfagna, F., Gonzalez, C., Grioni, S., Hiller, L., Jansson, J. H., Jørgensen, M. E., Jukema, J. W., Kaaks, R., Kee, F., Kerrison, N. D., Key, T. J., Kontto, J., Kote-Jarai, Z., Kraja, A. T., Kuulasmaa, K., Kuusisto, J., Linneberg, A., Liu, C., Marenne, G., Mohlke, K. L., Morris, A. P., Muir, K., Müller-Nurasyid, M., Munroe, P. B., Navarro, C., Nielsen, S. F., Nilsson, P. M., Nordestgaard, B. G., Packard, C. J., Palli, D., Panico, S., Peloso, G. M., Perola, M., Peters, A., Poole, C. J., Quirós, J. R., Rolandsson, O., Sacerdote, C., Salomaa, V., Sánchez, M. J., Sattar, N., Sharp, S. J., Sims, R., Slimani, N., Smith, J. A., Thompson, D. J., Trompet, S., Tumino, R., Van Der A, D. L., Van Der Schouw, Y. T., Virtamo, J., Walker, M., Walter, K., Abraham, J. E., Amundadottir, L. T., Butterworth, A. S., Aponte, J. L., Dupuis, J., Easton, D. F., Eeles, R. A., Erdmann, J., Franks, P. W., Frayling, T. M., Hansen, T., Howson, J. M. M., Jørgensen, T., Kooner, J., Laakso, M., McCarthy, M. I., Pankow, J. S., Pedersen, O., Riboli, E., Rotter, J. I., Saleheen, D., Samani, N. J., Schunkert, H., Vollenweider, P., O'Rahilly, S., Deloukas, P., Danesh, J., Goodarzi, M. O., Kathiresan, S., Meigs, J. B., Ehm, M. G., Wareham, N. J. & Waterworth, D. M., Jun 1 2016, In : Science Translational Medicine. 8, 341, 341ra76.

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45 Scopus citations

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Ried, J. S., Jeff, J. M., Chu, A. Y., Bragg-Gresham, J. L., Van Dongen, J., Huffman, J. E., Ahluwalia, T. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Standáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., Van Der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. D. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D'avila, F., De Geus, E. J. C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A. E., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. P., Glorioso, N., Graff, M., Grallert, H., Grarup, N., Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J. J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Marie Justesen, J., Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-Kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, A., Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., Mcardle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-Madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., Van Der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M. C., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-Armstrong, L. M., Zhao, J. H., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, T., Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M. R., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, O., Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, P. E. H., Shudiner, A. R., Smit, J. H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., Van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., Mccarthy, M. I., North, K. E., O'connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., Nov 23 2016, In : Nature communications. 7, 13357.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

Association of 1,5-anhydroglucitol with cardiovascular disease and mortality

Selvin, E., Rawlings, A., Lutsey, P., Maruthur, N., Pankow, J. S., Steffes, M. & Coresh, J., Jan 2016, In : Diabetes. 65, 1, p. 201-208 8 p.

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Open Access
32 Scopus citations

Association of lipid-related genetic variants with the incidence of atrial fibrillation: The AFGen consortium

Norby, F. L., Eryd, S. A., Niemeijer, M. N., Rose, L. M., Smith, A. V., Yin, X., Agarwal, S. K., Arking, D. E., Chasman, D. L., Chen, L. Y., Eijgelsheim, M., Engström, G., Franco, O. H., Heeringa, J., Hindy, G., Hofman, A., Lutsey, P. L., Magnani, J. W., McManus, D. D., Orho-Melander, M. & 10 others, Pankow, J. S., Rukh, G., Schulz, C. A., Uitterlinden, A. G., Albert, C. M., Benjamin, E. J., Gudnason, V., Smith, J. G., Stricker, B. H. C. & Alonso, A., Mar 2016, In : PloS one. 11, 3, e0151932.

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9 Scopus citations

Association of the IGF1 gene with fasting insulin levels

Willems, S. M., Cornes, B. K., Brody, J. A., Morrison, A. C., Lipovich, L., Dauriz, M., Chen, Y., Liu, C. T., Rybin, D. V., Gibbs, R. A., Muzny, D., Pankow, J. S., Psaty, B. M., Boerwinkle, E., Rotter, J. I., Siscovick, D. S., Vasan, R. S., Kaplan, R. C., Isaacs, A., Dupuis, J. & 2 others, van Duijn, C. M. & Meigs, J. B., Aug 1 2016, In : European Journal of Human Genetics. 24, 9, p. 1337-1343 7 p.

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Open Access
2 Scopus citations

Blood group antigen loci demonstrate multivariate genetic associations with circulating cellular adhesion protein levels in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Decker, P. A., Wassel, C. L., Pankow, J. S., Tang, W., Hanson, N. Q., Tsai, M. Y. & Bielinski, S. J., Apr 1 2016, In : Human Genetics. 135, 4, p. 415-423 9 p.

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Open Access

Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case–cohort analysis of the ARIC Study

Luft, V. C., Duncan, B. B., Schmidt, M. I., Chambless, L. E., Pankow, J. S., Hoogeveen, R. C., Couper, D. J. & Heiss, G., Oct 1 2016, In : Diabetic Medicine. 33, 10, p. 1392-1398 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Circulating cellular adhesion molecules and risk of diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)

Pankow, J. S., Decker, P. A., Berardi, C., Hanson, N. Q., Sale, M., Tang, W., Kanaya, A. M., Larson, N. B., Tsai, M. Y., Wassel, C. L. & Bielinski, S. J., Jul 1 2016, In : Diabetic Medicine. 33, 7, p. 985-991 7 p.

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10 Scopus citations

Circulating level of hepatocyte growth factor predicts incidence of type 2 diabetes mellitus: The Multi-Ethnic Study of Atherosclerosis (MESA)

Bancks, M. P., Bielinski, S. J., Decker, P. A., Hanson, N. Q., Larson, N. B., Sicotte, H., Wassel, C. L. & Pankow, J., Mar 1 2016, In : Metabolism: clinical and experimental. 65, 3, p. 64-72 9 p.

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Open Access
13 Scopus citations

DNA methylation-based measures of biological age: Meta-analysis predicting time to death

Chen, B. H., Marioni, R. E., Colicino, E., Peters, M. J., Ward-Caviness, C. K., Tsai, P. C., Roetker, N. S., Just, A. C., Demerath, E. W., Guan, W., Bressler, J., Fornage, M., Studenski, S., Vandiver, A. R., Moore, A. Z., Tanaka, T., Kiel, D. P., Liang, L., Vokonas, P., Schwartz, J. & 46 others, Lunetta, K. L., Murabito, J. M., Bandinelli, S., Hernandez, D. G., Melzer, D., Nalls, M., Pilling, L. C., Price, T. R., Singleton, A. B., Gieger, C., Holle, R., Kretschmer, A., Kronenberg, F., Kunze, S., Linseisen, J., Meisinger, C., Rathmann, W., Waldenberger, M., Visscher, P. M., Shah, S., Wray, N. R., McRae, A. F., Franco, O. H., Hofman, A., Uitterlinden, A. G., Absher, D., Assimes, T., Levine, M. E., Lu, A. T., Tsao, P. S., Hou, L., Manson, J. A. E., Carty, C. L., LaCroix, A. Z., Reiner, A. P., Spector, T. D., Feinberg, A. P., Levy, D., Baccarelli, A., Meurs, J. V., Bell, J. T., Peters, A., Deary, I. J., Pankow, J. S., Ferrucci, L. & Horvath, S., Jan 1 2016, In : Aging. 8, 9, p. 1844-1865 22 p.

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257 Scopus citations

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, S., Marzi, C., Aslibekyan, S., Mendelson, M. M., Conneely, K. N., Tanaka, T., Colicino, E., Waite, L. L., Joehanes, R., Guan, W., Brody, J. A., Elks, C., Marioni, R., Jhun, M. A., Agha, G., Bressler, J., Ward-Caviness, C. K., Chen, B. H., Huan, T., Bakulski, K. & 67 others, Salfati, E. L., Fiorito, G., Wahl, S., Schramm, K., Sha, J., Hernandez, D. G., Just, A. C., Smith, J. A., Sotoodehnia, N., Pilling, L. C., Pankow, J. S., Tsao, P. S., Liu, C., Zhao, W., Guarrera, S., Michopoulos, V. J., Smith, A. K., Peters, M. J., Melzer, D., Vokonas, P., Fornage, M., Prokisch, H., Bis, J. C., Chu, A. Y., Herder, C., Grallert, H., Yao, C., Shah, S., McRae, A. F., Lin, H., Horvath, S., Fallin, D., Hofman, A., Wareham, N. J., Wiggins, K. L., Feinberg, A. P., Starr, J. M., Visscher, P. M., Murabito, J. M., Kardia, S. L. R., Absher, D. M., Binder, E. B., Singleton, A. B., Bandinelli, S., Peters, A., Waldenberger, M., Matullo, G., Schwartz, J. D., Demerath, E. W., Uitterlinden, A. G., Meurs, J. B. J., Franco, O. H., Chen, Y. D. I., Levy, D., Turner, S. T., Deary, I. J., Ressler, K. J., Dupuis, J., Ferrucci, L., Ong, K. K., Assimes, T. L., Boerwinkle, E., Koenig, W., Arnett, D. K., Baccarelli, A. A., Benjamin, E. J. & Dehghan, A., Dec 12 2016, In : Genome biology. 17, 1, 255.

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Open Access
81 Scopus citations

Epigenetic Signatures of Cigarette Smoking

Joehanes, R., Just, A. C., Marioni, R. E., Pilling, L. C., Reynolds, L. M., Mandaviya, P. R., Guan, W., Xu, T., Elks, C. E., Aslibekyan, S., Moreno-Macias, H., Smith, J. A., Brody, J. A., Dhingra, R., Yousefi, P., Pankow, J. S., Kunze, S., Shah, S. H., McRae, A. F., Lohman, K. & 63 others, Sha, J., Absher, D. M., Ferrucci, L., Zhao, W., Demerath, E. W., Bressler, J., Grove, M. L., Huan, T., Liu, C., Mendelson, M. M., Yao, C., Kiel, D. P., Peters, A., Wang-Sattler, R., Visscher, P. M., Wray, N. R., Starr, J. M., Ding, J., Rodriguez, C. J., Wareham, N. J., Irvin, M. R., Zhi, D., Barrdahl, M., Vineis, P., Ambatipudi, S., Uitterlinden, A. G., Hofman, A., Schwartz, J., Colicino, E., Hou, L., Vokonas, P. S., Hernandez, D. G., Singleton, A. B., Bandinelli, S., Turner, S. T., Ware, E. B., Smith, A. K., Klengel, T., Binder, E. B., Psaty, B. M., Taylor, K. D., Gharib, S. A., Swenson, B. R., Liang, L., Demeo, D. L., O'Connor, G. T., Herceg, Z., Ressler, K. J., Conneely, K. N., Sotoodehnia, N., Kardia, S. L. R., Melzer, D., Baccarelli, A. A., Van Meurs, J. B. J., Romieu, I., Arnett, D. K., Ong, K. K., Liu, Y., Waldenberger, M., Deary, I. J., Fornage, M., Levy, D. & London, S. J., Oct 1 2016, In : Circulation: Cardiovascular Genetics. 9, 5, p. 436-447 12 p.

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213 Scopus citations

Erratum: Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (American Society for Clinical Investigation (2015)125:4 (1739-1751) DOI 10.1172/JCI74692)

Knowles, J. W., Xie, W., Zhang, Z., Chennamsetty, I., Assimes, T. L., Paananen, J., Hansson, O., Pankow, J., Goodarzi, M. O., Carcamo-Orive, I., Morris, A. P., Chen, Y. D. I., Mäkinen, V. P., Ganna, A., Mahajan, A., Guo, X., Abbasi, F., Greenawalt, D. M., Lum, P., Molony, C. & 19 others, Lind, L., Lindgren, C., Raffel, L. J., Tsao, P. S., Schadt, E. E., Rotter, J. I., Sinaiko, A., Reaven, G., Yang, X., Hsiung, C. A., Groop, L., Cordell, H. J., Laakso, M., Hao, K., Ingelsson, E., Frayling, T. M., Weedon, M. N., Walker, M. & Quertermous, T., Jan 4 2016, In : Journal of Clinical Investigation. 126, 1, 1 p.

Research output: Contribution to journalComment/debate

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5 Scopus citations