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2019
2 Citations (Scopus)

Adaptive NK cell reconstitution is associated with better clinical outcomes

Cichocki, F. M., Taras, E., Chiuppesi, F., Wagner, J. E., Blazar, B. R., Brunstein, C. G., Luo, X., Diamond, D. J., Cooley, S., Weisdorf, D. J. & Miller, J. S., Jan 24 2019, In : JCI Insight. 4, 2, Y.

Research output: Contribution to journalArticle

Open Access
Natural Killer Cells
Cytomegalovirus
Transplants
Hematologic Neoplasms
Hematopoietic Stem Cells
1 Citation (Scopus)
Epidermolysis Bullosa Dystrophica
Cyclophosphamide
Bone Marrow
Tissue Donors
Transplants

Comparative Analysis of Calcineurin Inhibitor–Based Methotrexate and Mycophenolate Mofetil–Containing Regimens for Prevention of Graft-versus-Host Disease after Reduced-Intensity Conditioning Allogeneic Transplantation

Chhabra, S., Liu, Y., Hemmer, M. T., Costa, L., Pidala, J. A., Couriel, D. R., Alousi, A. M., Majhail, N. S., Stuart, R. K., Kim, D., Ringden, O., Urbano-Ispizua, A., Saad, A., Savani, B. N., Cooper, B., Marks, D. I., Socie, G., Schouten, H. C., Schoemans, H., Abdel-Azim, H. & 26 others, Yared, J., Cahn, J. Y., Wagner, J. E., Antin, J. H., Verdonck, L. F., Lehmann, L., Aljurf, M. D., MacMillan, M. L., Litzow, M. R., Solh, M. M., Qayed, M., Hematti, P., Kamble, R. T., Vij, R., Hayashi, R. J., Gale, R. P., Martino, R., Seo, S., Hashmi, S. K., Nishihori, T., Teshima, T., Gergis, U., Inamoto, Y., Spellman, S. R., Arora, M. & Hamilton, B. K., Jan 1 2019, In : Biology of Blood and Marrow Transplantation. 25, 1, p. 73-85 13 p.

Research output: Contribution to journalArticle

Open Access
Calcineurin
Homologous Transplantation
Graft vs Host Disease
Methotrexate
Mycophenolic Acid
1 Citation (Scopus)

Cord blood research, banking, and transplantation: achievements, challenges, and perspectives

Mayani, H., Wagner, J. E. & Broxmeyer, H. E., Jan 1 2019, In : Bone marrow transplantation.

Research output: Contribution to journalReview article

Blood Banks
Fetal Blood
Transplantation
Research
Transplants
Cell Transplantation
Graft vs Host Disease
Morbidity
Recurrence
Survival
1 Citation (Scopus)

Elevations in serum alpha fetoprotein levels in patients with Fanconi anaemia

Salem, B., Mitchell, R., De For, T. E., Tryon, R., Wagner, J. E. & MacMillan, M. L., Mar 1 2019, In : British Journal of Haematology. 184, 6, p. 1032-1035 4 p.

Research output: Contribution to journalLetter

Open Access
Fanconi Anemia
alpha-Fetoproteins
Serum
Cell Transplantation
Monocytes
Survival
Transplants
Fetal Blood
7 Citations (Scopus)

Phase I/II study of stem-cell transplantation using a single cord blood unit expanded ex vivo with nicotinamide

Horwitz, M. E., Wease, S., Blackwell, B., Valcarcel, D., Frassoni, F., Boelens, J. J., Nierkens, S., Jagasia, M., Wagner, J. E., Kuball, J., Koh, L. P., Majhail, N. S., Stiff, P. J., Hanna, R., Hwang, W. Y. K., Kurtzberg, J., Cilloni, D., Freedman, L. S., Montesinos, P. & Sanz, G., Feb 10 2019, In : Journal of Clinical Oncology. 37, 5, p. 367-374 8 p.

Research output: Contribution to journalArticle

Open Access
Niacinamide
Stem Cell Transplantation
Fetal Blood
Graft vs Host Disease
Transplants

Predictive value of disease risk comorbidity index for overall survival after allogeneic hematopoietic transplantation

Bejanyan, N., Brunstein, C. G., Cao, Q., Lazaryan, A., Ustun, C., Warlick, E. D., Arora, M., Wagner, J. E. & Weisdorf, D. J., Feb 12 2019, In : Blood Advances. 3, 3, p. 230-236 7 p.

Research output: Contribution to journalArticle

Open Access
Homologous Transplantation
Comorbidity
Survival
Cell Transplantation
Hematologic Neoplasms
1 Citation (Scopus)

The influence of stem cell source on transplant outcomes for pediatric patients with acute myeloid leukemia

Keating, A. K., Langenhorst, J., Wagner, J. E., Page, K. M., Veys, P., Wynn, R. F., Stefanski, H. E., Elfeky, R., Giller, R., Mitchell, R., Milano, F., O’Brien, T. A., Dahlberg, A., Delaney, C., Kurtzberg, J., Verneris, M. R. & Boelens, J. J., Apr 9 2019, In : Blood Advances. 3, 7, p. 1118-1128 11 p.

Research output: Contribution to journalArticle

Open Access
Acute Myeloid Leukemia
Stem Cells
Fetal Blood
Pediatrics
Transplants
2018
5 Citations (Scopus)
Fanconi Anemia
Aplastic Anemia
Cell Transplantation
Siblings
Tissue Donors
4 Citations (Scopus)

Delayed immune reconstitution after allogeneic transplantation increases the risks of mortality and chronic GVHD

Bejanyan, N., Brunstein, C. G., Cao, Q., Lazaryan, A., Luo, X., Curtsinger, J. M., Mehta, R. S., Warlick, E. D., Cooley, S. A., Blazar, B. R., Miller, J. S., Weisdorf, D., Wagner, J. E. & Verneris, M. R., Apr 24 2018, In : Blood Advances. 2, 8, p. 909-922 14 p.

Research output: Contribution to journalArticle

Open Access
Homologous Transplantation
Graft vs Host Disease
Siblings
Tissue Donors
Mortality
3 Citations (Scopus)

Early Reconstitution of NK and γδ T Cells and Its Implication for the Design of Post-Transplant Immunotherapy

de Witte, M. A., Sarhan, D. A., Davis, Z. B., Felices, M., Vallera, D. A., Hinderlie, P., Curtsinger, J. M., Cooley, S. A., Wagner, J. E., Kuball, J. & Miller, J. S., Jun 1 2018, In : Biology of Blood and Marrow Transplantation. 24, 6, p. 1152-1162 11 p.

Research output: Contribution to journalArticle

Open Access
Natural Killer T-Cells
Hematopoietic Stem Cell Transplantation
Immunotherapy
T-Lymphocytes
Transplants
50 Citations (Scopus)

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Romee, R., Cooley, S. A., Berrien-Elliott, M. M., Westervelt, P., Verneris, M. R., Wagner, J. E., Weisdorf, D. J., Blazar, B. R., Ustun, C., De For, T. E., Vivek, S., Peck, L., DiPersio, J. F., Cashen, A. F., Kyllo, R., Musiek, A., Schaffer, A., Anadkat, M. J., Rosman, I., Miller, D. D. & 6 others, Egan, J. O., Jeng, E. K., Rock, A., Wong, H. C., Fehniger, T. A. & Miller, J. S., Jun 7 2018, In : Blood. 131, 23, p. 2515-2527 13 p.

Research output: Contribution to journalArticle

Interleukin-15
T-cells
Transplantation
Recurrence
Cell Transplantation
3 Citations (Scopus)

Inside out: Regenerative medicine for recessive dystrophic epidermolysis bullosa

Vanden Oever, M., Twaroski, K., Osborn, M. J., Wagner, J. E. & Tolar, J., Jan 1 2018, In : Pediatric Research. 83, 1-2, p. 318-324 7 p.

Research output: Contribution to journalReview article

Epidermolysis Bullosa Dystrophica
Epidermolysis Bullosa
Regenerative Medicine
Mesenchymal Stromal Cells
Induced Pluripotent Stem Cells
2017
13 Citations (Scopus)

Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation

Dietz, A. C., Mehta, P. A., Vlachos, A., Savage, S. A., Bresters, D., Tolar, J., Boulad, F., Dalle, J. H., Bonfim, C., de la Fuente, J., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P., May 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 5, p. 726-735 10 p.

Research output: Contribution to journalArticle

Open Access
Cell Transplantation
Fanconi Anemia
Bone Marrow
Pediatrics
Transplants
19 Citations (Scopus)
Fanconi Anemia
Cell Transplantation
Investigational Therapies
Transplants
Survival
Fetal Blood
Transplantation
Neutrophils
Blood Platelets
Incidence
9 Citations (Scopus)

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines

Hippen, K. L., O'Connor, R. S., Lemire, A. M., Saha, A., Hanse, E. A., Tennis, N. C., Merkel, S. C., Kelekar, A., Riley, J. L., Levine, B. L., June, C. H., Turka, L. A., Kean, L. S., MacMillan, M. L., Miller, J. S., Wagner, J. E., Munn, D. H. & Blazar, B. R., Dec 1 2017, In : American Journal of Transplantation. 17, 12, p. 3098-3113 16 p.

Research output: Contribution to journalArticle

Open Access
Kynurenine
Regulatory T-Lymphocytes
Tryptophan
Graft vs Host Disease
Interleukin-2
6 Citations (Scopus)

Late Effects Screening Guidelines after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement From the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects After Pediatric HCT

Dietz, A. C., Savage, S. A., Vlachos, A., Mehta, P. A., Bresters, D., Tolar, J., Bonfim, C., Dalle, J. H., de la Fuente, J., Skinner, R., Boulad, F., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P., Sep 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 9, p. 1422-1428 7 p.

Research output: Contribution to journalArticle

Open Access
Cell Transplantation
Bone Marrow
Guidelines
Pediatrics
Transplants
Risk Management
Ice
Immunocompromised Host
Mycobacterium
Hematopoietic Stem Cells
3 Citations (Scopus)

Matching at Human Leukocyte Antigen-C Improved the Outcomes after Double Umbilical Cord Blood Transplantation for Recipients of Two to Four of Six Human Leukocyte Antigen–Matched Grafts

Brunstein, C. G., Cutler, C. S., DeFor, T. E., Kim, H., Bejanyan, N., Garfall, A., Verneris, M. R., Chen, Y. B., Warlick, E. D., Spitzer, T., Miller, J. S., Antin, J. H., Weisdorf, D. J., Soiffer, R., Wagner, J. E. & Ballen, K. K., Jan 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 1, p. 126-133 8 p.

Research output: Contribution to journalArticle

Open Access
HLA-C Antigens
HLA Antigens
Fetal Blood
Leukocytes
Transplantation
19 Citations (Scopus)

Optimal Practices in Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies

Barker, J. N., Kurtzberg, J., Ballen, K., Boo, M., Brunstein, C., Cutler, C., Horwitz, M., Milano, F., Olson, A., Spellman, S., Wagner, J. E., Delaney, C. & Shpall, E., Jun 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 6, p. 882-896 15 p.

Research output: Contribution to journalReview article

Open Access
Unrelated Donors
Hematologic Neoplasms
Fetal Blood
Transplantation
Graft vs Host Disease
16 Citations (Scopus)

Optimization of cGMP purification and expansion of umbilical cord blood–derived T-regulatory cells in support of first-in-human clinical trials

McKenna, D. H., Sumstad, D., Kadidlo, D. M., Batdorf, B., Lord, C. J., Merkel, S. C., Koellner, C. M., Curtsinger, J. M., June, C. H., Riley, J. L., Levine, B. L., Miller, J. S., Brunstein, C. G., Wagner, J. E., Blazar, B. R. & Hippen, K. L., Feb 1 2017, In : Cytotherapy. 19, 2, p. 250-262 13 p.

Research output: Contribution to journalArticle

Umbilical Cord
Regulatory T-Lymphocytes
Fetal Blood
Clinical Trials
Graft vs Host Disease
1 Citation (Scopus)
Fanconi Anemia
Mutation
Inborn Genetic Diseases
Bone Marrow
Phenotype
15 Citations (Scopus)

The Second Pediatric Blood and Marrow Transplant Consortium International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: Defining the Unique Late Effects of Children Undergoing Hematopoietic Cell Transplantation for Immune Deficiencies, Inherited Marrow Failure Disorders, and Hemoglobinopathies

Dietz, A. C., Duncan, C. N., Alter, B. P., Bresters, D., Cowan, M. J., Notarangelo, L., Rosenberg, P. S., Shenoy, S., Skinner, R., Walters, M. C., Wagner, J., Baker, K. S. & Pulsipher, M. A., Jan 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 1, p. 24-29 6 p.

Research output: Contribution to journalArticle

Open Access
Hemoglobinopathies
Cell Transplantation
Transplantation
Bone Marrow
Pediatrics
4 Citations (Scopus)

Umbilical Cord Blood Transplantation in Children with Acute Leukemia: Impact of Conditioning on Transplantation Outcomes

Eapen, M., Kurtzberg, J., Zhang, M. J., Hattersely, G., Fei, M., Mendizabal, A., Chan, K. W., De Oliveira, S., Schultz, K. R., Wall, D., Horowitz, M. M. & Wagner, J. E., Oct 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 10, p. 1714-1721 8 p.

Research output: Contribution to journalArticle

Open Access
Transplantation Conditioning
Fetal Blood
Leukemia
Transplantation
Survival
2016
81 Citations (Scopus)

CD56 dim CD57+ NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT

Cichocki, F. M., Cooley, S. A., Davis, Z. B., De For, T. E., Schlums, H., Zhang, B., Brunstein, C. G., Blazar, B. R., Wagner, J. E., Diamond, D. J., Verneris, M. R., Bryceson, Y. T., Weisdorf, D. J. & Miller, J. S., Feb 1 2016, In : Leukemia. 30, 2, p. 456-463 8 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Natural Killer Cells
Leukemia
Transplants
Recurrence
14 Citations (Scopus)

CRISPR/Cas9 targeted gene editing and cellular engineering in fanconi anemia

Osborn, M. J., Lonetree, C. L., Webber, B. R., Patel, D. D., Dunmire, S., DeFeo, A. P., McElroy, A. N., MacMillan, M. L., Wagner, J. E., Blazar, B. R. & Tolar, J., Oct 15 2016, In : Stem Cells and Development. 25, 20, p. 1591-1603 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Cell Engineering
Fanconi Anemia
Induced Pluripotent Stem Cells
Genes
8 Citations (Scopus)
Fanconi Anemia
Cell Transplantation
Insulin Resistance
Bone and Bones
Health

Establishing the UCB graft potentiality

Wagner, J. E., May 12 2016, In : Blood. 127, 19, p. 2272-2274 3 p.

Research output: Contribution to journalArticle

Aldehyde Dehydrogenase
Fetal Blood
Reproducibility of Results
Grafts
Blood
4 Citations (Scopus)

Fatal myocarditis associated with HHV-6 following immunosuppression in two children

Stefanski, H. E., Thibert, K. A., Pritchett, J., Prusty, B. K., Wagner, J. E. & Lund, T. C., Jan 1 2016, In : Pediatrics. 137, 1, e20151352.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Myocarditis
Immunosuppression
Herpesviridae Infections
Hematopoietic Stem Cell Transplantation

Hematopoietic Cell Transplantation for Fanconi Anemia

Wagner, J. E., Tolar, J., Auerbach, A. D. & MacMillan, M. L., Jan 1 2016, Thomas' Hematopoietic Cell Transplantation: Fifth Edition. Wiley Blackwell, Vol. 2-2. p. 923-946 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fanconi Anemia
Cell Transplantation
Bone Marrow
Radiation
Inborn Genetic Diseases
15 Citations (Scopus)
Fetal Blood
Transplantation
Alleles
Treatment Failure
Leukemia
5 Citations (Scopus)
Graft vs Host Disease
Helper-Inducer T-Lymphocytes
Fetal Blood
Transplantation
B-Lymphocytes
9 Citations (Scopus)
Leuprolide
Cell Transplantation
Gonadotropin-Releasing Hormone
Observation
Transplants
3 Citations (Scopus)

Paternal or Maternal Uniparental Disomy of Chromosome 16 Resulting in Homozygosity of a Mutant Allele Causes Fanconi Anemia

Donovan, F. X., Kimble, D. C., Kim, Y., Lach, F. P., Harper, U., Kamat, A., Jones, M., Sanborn, E. M., Tryon, R., Wagner, J. E., MacMillan, M. L., Ostrander, E. A., Auerbach, A. D., Smogorzewska, A. & Chandrasekharappa, S. C., May 1 2016, In : Human Mutation. 37, 5, p. 465-468 4 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Uniparental Disomy
Alleles
Mothers
Chromosomes, Human, Pair 16
7 Citations (Scopus)

Personalized fludarabine dosing to reduce nonrelapse mortality in hematopoietic stem-cell transplant recipients receiving reduced intensity conditioning

Sanghavi, K. J., Wiseman, A., Kirstein, M. N., Cao, Q., Brundage, R., Jensen, K., Rogosheske, J., Kurtzweil, A., Long-Boyle, J., Wagner, J. E., Warlick, E. D., Brunstein, C. G., Weisdorf, D. J. & Jacobson, P. A., Sep 1 2016, In : Translational Research. 175, p. 103-115.e4

Research output: Contribution to journalArticle

Transplants
Hematopoietic Stem Cells
Stem cells
Mortality
Cell Transplantation
107 Citations (Scopus)

Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

Wagner, J. E., Brunstein, C. G., Boitano, A. E., Defor, T. E., McKenna, D., Sumstad, D., Blazar, B. R., Tolar, J., Le, C., Jones, J., Cooke, M. P. & Bleul, C. C., Jan 7 2016, In : Cell Stem Cell. 18, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Fetal Blood
Transplants
Aryl Hydrocarbon Receptors
Hematopoietic Stem Cell Transplantation
21 Citations (Scopus)
Cell Transplantation
Graft vs Host Disease
Fetal Blood
Incidence
Recurrence
2 Citations (Scopus)
Mycophenolic Acid
Calcineurin
Graft vs Host Disease
Sirolimus
Fetal Blood
13 Citations (Scopus)
Adoptive Transfer
Cell Transplantation
Natural Killer Cells
Transplants
Neoplasms
4 Citations (Scopus)

Toxic epidermal necrolysis in recessive dystrophic epidermolysis bullosa following bone marrow transplantation

Boull, C. L., Hylwa, S. A., Sajic, D., Wagner, J. E., Tolar, J. & Hook, K. P., Jun 1 2016, In : Journal of Pediatrics. 173, p. 242-244 3 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa Dystrophica
Stevens-Johnson Syndrome
Bone Marrow Transplantation
Epidermolysis Bullosa
Re-Epithelialization
122 Citations (Scopus)

Umbilical cord blood-derived T regulatory cells to prevent GVHD: Kinetics, toxicity profile, and clinical effect

Brunstein, C. G., Miller, J. S., McKenna, D. H., Hippen, K. L., DeFor, T. E., Sumstad, D., Curtsinger, J., Verneris, M. R., MacMillan, M. L., Levine, B. L., Riley, J. L., June, C. H., Le, C., Weisdorf, D. J., McGlave, P. B., Blazar, B. R. & Wagner, J. E., Feb 25 2016, In : Blood. 127, 8, p. 1044-1051 8 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Regulatory T-Lymphocytes
Fetal Blood
Grafts
Toxicity
3 Citations (Scopus)
Fetal Blood
Acute Myeloid Leukemia
Transplantation
2015
8 Citations (Scopus)

A biologic Velcro patch

Tolar, J. & Wagner, J. E., Jan 22 2015, In : New England Journal of Medicine. 372, 4, p. 382-384 3 p.

Research output: Contribution to journalArticle

Collagen Type VII
Epidermolysis Bullosa Dystrophica
Induced Pluripotent Stem Cells
Combined Modality Therapy
Skin Transplantation
26 Citations (Scopus)
KIR Receptors
Cell Transplantation
Cytomegalovirus
Natural Killer Cells
Tissue Donors
108 Citations (Scopus)

A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

Wang, A. T., Kim, T., Wagner, J. E., Conti, B. A., Lach, F. P., Huang, A. L., Molina, H., Sanborn, E. M., Zierhut, H., Cornes, B. K., Abhyankar, A., Sougnez, C., Gabriel, S. B., Auerbach, A. D., Kowalczykowski, S. C. & Smogorzewska, A., Aug 6 2015, In : Molecular Cell. 59, 3, p. 478-490 13 p.

Research output: Contribution to journalArticle

Recombinational DNA Repair
Homologous Recombination
Recombinases
Mutation
DNA
38 Citations (Scopus)

Advances in umbilical cord blood manipulation-from niche to bedside

Lund, T. C., Boitano, A. E., Delaney, C. S., Shpall, E. J. & Wagner, J. E., Mar 28 2015, In : Nature Reviews Clinical Oncology. 12, 3, p. 163-174 12 p.

Research output: Contribution to journalReview article

Hematopoietic Stem Cells
Fetal Blood
Bone Marrow
Allografts
Transplantation
48 Citations (Scopus)
Fanconi Anemia
Cell Transplantation
Antilymphocyte Serum
Tissue Donors
Cyclophosphamide