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2019

Changes in Albuminuria But Not GFR are Associated with Early Changes in Kidney Structure in Type 2 Diabetes

Looker, H. C., Mauer, M., Saulnier, P. J., Harder, J. L., Nair, V., Boustany-Kari, C. M., Guarnieri, P., Hill, J., Esplin, C. A., Kretzler, M., Nelson, R. G. & Najafian, B., Jun 1 2019, In : Journal of the American Society of Nephrology : JASN. 30, 6, p. 1049-1059 11 p.

Research output: Contribution to journalArticle

Albuminuria
Type 2 Diabetes Mellitus
Albumins
Creatinine
Glomerular Basement Membrane

Genetic determinants of glycated hemoglobin in type 1 diabetes

DCCT/EDIC Research Group, Per-Henrik Groop & FinnDiane Study Group, Apr 1 2019, In : Diabetes. 68, 4, p. 858-867 10 p.

Research output: Contribution to journalArticle

Open Access
Glycosylated Hemoglobin A
Type 1 Diabetes Mellitus
Single Nucleotide Polymorphism
Meta-Analysis
Relaxin

Low-dose agalsidase beta treatment in male pediatric patients with Fabry disease: A 5-year randomized controlled trial

Ramaswami, U., Bichet, D. G., Clarke, L. A., Dostalova, G., Fainboim, A., Fellgiebel, A., Forcelini, C. M., An Haack, K., Hopkin, R. J., Mauer, M., Najafian, B., Scott, C. R., Shankar, S. P., Thurberg, B. L., Tøndel, C., Tylki-Szymanska, A., Bénichou, B. & Wijburg, F. A., Jan 1 2019, In : Molecular Genetics and Metabolism.

Research output: Contribution to journalArticle

Open Access
Fabry Disease
Pediatrics
Randomized Controlled Trials
Skin
Urine
1 Citation (Scopus)

Preventing Early Renal Loss in Diabetes (PERL) Study: A Randomized Double-Blinded Trial of Allopurinol-Rationale, Design, and Baseline Data

PERL Study Group, Aug 2019, In : Diabetes care. 42, 8, p. 1454-1463 10 p.

Research output: Contribution to journalArticle

Allopurinol
Diabetic Nephropathies
Uric Acid
Glomerular Filtration Rate
Albuminuria
2018
6 Citations (Scopus)

Biological Variability of Estimated GFR and Albuminuria in CKD

Waikar, S. S., Rebholz, C. M., Zheng, Z., Hurwitz, S., Hsu, C. Y., Feldman, H. I., Xie, D., Liu, K. D., Mifflin, T. E., Eckfeldt, J. H., Kimmel, P. L., Vasan, R. S., Bonventre, J. V., Inker, L. A., Coresh, J., Ramachandran, V. S., Bonventre, J., Waikar, S., Sabbisetti, V., Van Eyk, J. & 29 others, Chen, D., Fu, Q., Brunner, H., D'Agati, V., Barasch, J., Coresh, J., Rebholz, C., Go, A. S., Bottinger, E., Teixeira, A., Daehn, I., Molitch, M., Batlle, D., Rovin, B., Wu, H., Levey, A. S., Inker, L. A., Foster, M., Hsu, C. Y., Liu, K., Klein, J., Fioretto, P., Mauer, M., Eckfeldt, J. H., Karger, A., Feldman, H. I., Karger, A., Whitehead, K. & Xie, D., Oct 1 2018, In : American Journal of Kidney Diseases. 72, 4, p. 538-546 9 p.

Research output: Contribution to journalArticle

Albuminuria
Albumins
Creatinine
prostaglandin R2 D-isomerase
Glomerular Filtration Rate
35 Citations (Scopus)

Fabry disease revisited: Management and treatment recommendations for adult patients

Ortiz, A., Germain, D. P., Desnick, R. J., Politei, J., Mauer, M., Burlina, A., Eng, C., Hopkin, R. J., Laney, D., Linhart, A., Waldek, S., Wallace, E., Weidemann, F. & Wilcox, W. R., Apr 1 2018, In : Molecular Genetics and Metabolism. 123, 4, p. 416-427 12 p.

Research output: Contribution to journalReview article

Fabry Disease
Disease Management
Enzyme Replacement Therapy
Pediatrics
Phenotype

Role of Kidney Biopsies for Biomarker Discovery in Diabetic Kidney Disease

Looker, H. C., Mauer, M. & Nelson, R. G., Mar 1 2018, In : Advances in Chronic Kidney Disease. 25, 2, p. 192-201 10 p.

Research output: Contribution to journalReview article

Diabetic Nephropathies
Biomarkers
Kidney
Biopsy
Albuminuria

Uric Acid and Diabetic Nephropathy Risk

Mauer, M. & Doria, A., Jan 1 2018, In : Contributions to nephrology. 192, p. 103-109 7 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Uric Acid
Glomerular Filtration Rate
Chronic Kidney Failure
Allopurinol

Urinary IgG4 and Smad1 are specific biomarkers for renal structural and functional changes in early stages of diabetic nephropathy

Doi, T., Moriya, T., Fujita, Y., Minagawa, N., Usami, M., Sasaki, T., Abe, H., Kishi, S., Murakami, T., Ouchi, M., Ichien, G., Yamamoto, K., Ikeda, H., Koezuka, Y., Takamatsu, N., Shima, K., Mauer, M., Nagai, K. & Tominaga, T., May 1 2018, In : Diabetes. 67, 5, p. 986-993 8 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Immunoglobulin G
Biomarkers
Glomerular Filtration Rate
Kidney

Urine inositol pentakisphosphate 2-kinase and changes in kidney structure in early diabetic kidney disease in type 1 diabetes

CKD Biomarkers Consortium, Nov 1 2018, In : American journal of physiology. Renal physiology. 315, 5, p. F1484-F1492

Research output: Contribution to journalArticle

Open Access
Diabetic Nephropathies
Type 1 Diabetes Mellitus
Urine
Kidney
Creatinine
2 Citations (Scopus)

White blood cell fractions correlate with lesions of diabetic kidney disease and predict loss of kidney function in Type 2 diabetes

Wheelock, K. M., Saulnier, P. J., Tanamas, S. K., Vijayakumar, P., Weil, E. J., Looker, H. C., Hanson, R. L., Lemley, K. V., Yee, B., Knowler, W. C., Hadjadj, S., Najafian, B., Mauer, M. & Nelson, R. G., Jun 1 2018, In : Nephrology Dialysis Transplantation. 33, 6, p. 1001-1009 9 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Type 2 Diabetes Mellitus
Leukocytes
Kidney
Lymphocytes
2017
17 Citations (Scopus)

Challenges in conducting clinical trials in nephrology: conclusions from a Kidney Disease—Improving Global Outcomes (KDIGO) Controversies Conference

KDIGO Controversies Conference on Challenges in the Conduct of Clinical Trials in Nephrology Conference Participants & KDIGO Controversies Conference on Challenges in the Conduct of Clinical Trials in Nephrology Conference Participants, Aug 1 2017, In : Kidney international. 92, 2, p. 297-305 9 p.

Research output: Contribution to journalArticle

Nephrology
Kidney Diseases
Clinical Trials
Kidney
Health Care Costs
8 Citations (Scopus)

Outcomes and Risk Factors for Graft Loss: Lessons Learned from 1,056 Pediatric Kidney Transplants at the University of Minnesota

Chinnakotla, S., Verghese, P., Chavers, B., Rheault, M. N., Kirchner, V., Dunn, T., Kashtan, C., Nevins, T., Mauer, M., Pruett, T., Kim, Y., Najera, L., Hanna, C., Kizilbash, S., Cook, M., Cisek, L. J., Gillingham, K., Yang, Y., Matas, A. & Najarian, J., Apr 1 2017, In : Journal of the American College of Surgeons. 224, 4, p. 473-486 14 p.

Research output: Contribution to journalArticle

Pediatrics
Transplants
Kidney
Living Donors
Tissue Donors
2 Citations (Scopus)

Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus

Wheelock, K. M., Cai, J., Looker, H. C., Merchant, M. L., Nelson, R. G., Fufaa, G. D., Weil, E. J., Feldman, H. I., Vasan, R. S., Kimmel, P. L., Rovin, B. H., Mauer, M. & Klein, J. B., Jul 1 2017, In : PloS one. 12, 7, e0180964.

Research output: Contribution to journalArticle

Open Access
diabetic nephropathy
bradykinin
insulin-dependent diabetes mellitus
Diabetic Nephropathies
Bradykinin
9 Citations (Scopus)

Reduction of podocyte globotriaosylceramide content in adult male patients with Fabry disease with amenable GLA mutations following 6 months of migalastat treatment

Mauer, M., Sokolovskiy, A., Barth, J. A., Castelli, J. P., Williams, H. N., Benjamin, E. R. & Najafian, B., Nov 1 2017, In : Journal of Medical Genetics. 54, 11, p. 781-786 6 p.

Research output: Contribution to journalArticle

Galactosidases
Fabry Disease
Podocytes
Mutation
Enzymes

Serum cystatin C in youth with diabetes: The SEARCH for diabetes in youth study

Kanakatti Shankar, R., Dolan, L. M., Isom, S., Saydah, S., Maahs, D. M., Dabelea, D., Reynolds, K., Hirsch, I. B., Rodriguez, B. L., Mayer-Davis, E. J., Marcovina, S., D'Agostino, R., Mauer, M. & Mottl, A. K., Aug 1 2017, In : Diabetes Research and Clinical Practice. 130, p. 258-265 8 p.

Research output: Contribution to journalArticle

Open Access
Cystatin C
Type 2 Diabetes Mellitus
Type 1 Diabetes Mellitus
Serum
Nutrition Surveys
1 Citation (Scopus)

White blood cell fractions correlate with lesions of diabetic kidney disease and predict loss of kidney function in Type 2 diabetes

Wheelock, K. M., Saulnier, P. J., Tanamas, S. K., Vijayakumar, P., Weil, E. J., Looker, H. C., Hanson, R. L., Lemley, K. V., Yee, B., Knowler, W. C., Hadjadj, S., Najafian, B., Mauer, M. & Nelson, R. G., Dec 1 2017, In : Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 32, 12, 1 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Type 2 Diabetes Mellitus
Leukocytes
Kidney
2016
11 Citations (Scopus)

Advanced glycation end products predict loss of renal function and correlate with lesions of diabetic kidney disease in American indians with type 2 diabetes

Saulnier, P. J., Wheelock, K. M., Howell, S., Weil, E. J., Tanamas, S. K., Knowler, W. C., Lemley, K. V., Mauer, M., Yee, B., Nelson, R. G. & Beisswenger, P. J., Dec 1 2016, In : Diabetes. 65, 12, p. 3744-3753 10 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
North American Indians
Diabetic Nephropathies
Type 2 Diabetes Mellitus
Kidney
7 Citations (Scopus)

Association between blood pressure and adverse renal events in type 1 diabetes

Ku, E., McCulloch, C. E., Mauer, M., Gitelman, S. E., Grimes, B. A. & Hsu, C. Y., Jan 1 2016, In : Diabetes Care. 39, 12, p. 2218-2224 7 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Blood Pressure
Kidney
Diabetes Complications
Glomerular Filtration Rate
37 Citations (Scopus)

Management of patients with diabetes and CKD: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

Perkovic, V., Agarwal, R., Fioretto, P., Hemmelgarn, B. R., Levin, A., Thomas, M. C., Wanner, C., Kasiske, B. L., Wheeler, D. C., Groop, P. H., Bakris, G. L., Cooper, M. E., Chae, D. W., Davidson, M. H., de Boer, I. H., de Zeeuw, D., Fornoni, A., Gnudi, L., Herzog, C. A., Hung, A. M. & 30 others, Jafar, T. H., Jardine, M., Jha, V., Ji, L., Kahn, S. E., Langham, R. G., Lerma, E. V., Ma, R. C. W., Makino, H., Marre, M., Mauer, M., Metsärinne, K., Nelson, R. G., Pecoits-Filho, R., Pollock, C. A., Rajapurkar, M., Rossing, P., Rychlík, I., Sharma, K., Stanton, R. C., Tesař, V., Tikkanen, I., Tomson, C. R. V., Toto, R. D., Tsukamoto, Y., Tuttle, K. R., Wada, T., Williams, W. W., Zhang, H. & Zoungas, S., Dec 1 2016, In : Kidney international. 90, 6, p. 1175-1183 9 p.

Research output: Contribution to journalArticle

Kidney Diseases
Chronic Kidney Failure
Investigational Therapies
Vulnerable Populations
Chronic Renal Insufficiency
12 Citations (Scopus)

One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease

Najafian, B., Tøndel, C., Svarstad, E., Sokolovkiy, A., Smith, K. & Mauer, M., Jan 1 2016, In : PloS one. 11, 4, p. e0152812

Research output: Contribution to journalArticle

Enzyme Replacement Therapy
Fabry Disease
Podocytes
therapeutics
Enzymes
18 Citations (Scopus)

Predicting decline of kidney function in lupus nephritis using urine biomarkers

Abulaban, K. M., Song, H., Zhang, X., Kimmel, P. L., Kusek, J. W., Nelson, R. G., Feldman, H. I., Vasan, R. S., Ying, J., Mauer, M., Nelsestuen, G. L., Bennett, M., Brunner, H. I. & Rovin, B. H., Aug 1 2016, In : Lupus. 25, 9, p. 1012-1018 7 p.

Research output: Contribution to journalArticle

Lupus Nephritis
Fatty Acid-Binding Proteins
Biomarkers
Urine
Chemokine CCL2
7 Citations (Scopus)

Risk factors for severe clinical events in male and female patients with Fabry disease treated with agalsidase beta enzyme replacement therapy: Data from the Fabry Registry

Hopkin, R. J., Cabrera, G., Charrow, J., Lemay, R., Martins, A. M., Mauer, M., Ortiz, A., Patel, M. R., Sims, K., Waldek, S., Warnock, D. G. & Wilcox, W. R., Sep 1 2016, In : Molecular Genetics and Metabolism. 119, 1-2, p. 151-159 9 p.

Research output: Contribution to journalArticle

Enzyme Replacement Therapy
Fabry Disease
Registries
Enzymes
Kidney
20 Citations (Scopus)

Structural predictors of loss of renal function in american indians with type 2 diabetes

Fufaa, G. D., Weil, E. J., Lemley, K. V., Knowler, W. C., Brosius, F. C., Yee, B., Mauer, M. & Nelson, R. G., Feb 5 2016, In : Clinical Journal of the American Society of Nephrology. 11, 2, p. 254-261 8 p.

Research output: Contribution to journalArticle

North American Indians
Type 2 Diabetes Mellitus
Kidney
Confidence Intervals
Clinical Trials
3 Citations (Scopus)

The dose-response effect of insulin sensitivity on albuminuria in children according to diabetes type

SEARCH for Diabetes in Youth Study, Jan 11 2016, In : Pediatric Nephrology. 31, 6, p. 933-940 8 p.

Research output: Contribution to journalArticle

Albuminuria
Insulin Resistance
Albumins
Urine
Creatinine
24 Citations (Scopus)

The management and treatment of children with Fabry disease: A United States-based perspective

Hopkin, R. J., Jefferies, J. L., Laney, D. A., Lawson, V. H., Mauer, M., Taylor, M. R. & Wilcox, W. R., Feb 1 2016, In : Molecular Genetics and Metabolism. 117, 2, p. 104-113 10 p.

Research output: Contribution to journalReview article

Fabry Disease
Kidney
Hypohidrosis
Therapeutics
Pediatrics
30 Citations (Scopus)

Time to treatment benefit for adult patients with Fabry disease receiving agalsidase β: Data from the Fabry Registry

Ortiz, A., Abiose, A., Bichet, D. G., Cabrera, G., Charrow, J., Germain, D. P., Hopkin, R. J., Jovanovic, A., Linhart, A., Maruti, S. S., Mauer, M., Oliveira, J. P., Patel, M. R., Politei, J., Waldek, S., Wanner, C., Yoo, H. W. & Warnock, D. G., Jul 1 2016, In : Journal of medical genetics. 53, 7, p. 495-502 8 p.

Research output: Contribution to journalArticle

Fabry Disease
Registries
Incidence
Therapeutics
Galactosidases
12 Citations (Scopus)

Urinary podocyte loss is increased in patients with fabry disease and correlates with clinical severity of fabry nephropathy

Fall, B., Scott, C. R., Mauer, M., Shankland, S., Pippin, J., Jefferson, J. A., Wallace, E., Warnock, D. & Najafian, B., Dec 1 2016, In : PloS one. 11, 12, e0168346.

Research output: Contribution to journalArticle

Fabry Disease
Podocytes
kidney diseases
Creatinine
Healthy Volunteers
2015
23 Citations (Scopus)

Characterization of early disease status in treatment-naive male paediatric patients with fabry disease enrolled in a randomized clinical trial

Wijburg, F. A., Bénichou, B., Bichet, D. G., Clarke, L. A., Dostalova, G., Fainboim, A., Fellgiebel, A., Forcelini, C., Haack, K. A., Hopkin, R. J., Mauer, M., Najafian, B., Scott, C. R., Shankar, S. P., Thurberg, B. L., Tøndel, C., Tylki-Szymańska, A. & Ramaswami, U., May 1 2015, In : PloS one. 10, 5, e0124987.

Research output: Contribution to journalArticle

Fabry Disease
Pediatrics
randomized clinical trials
Endothelial cells
Randomized Controlled Trials
15 Citations (Scopus)

Cross-disciplinary biomarkers research: Lessons learned by the CKD biomarkers consortium

Hsu, C. Y., Ballard, S., Batlle, D., Bonventre, J. V., Böttinger, E. P., Feldman, H. I., Klein, J. B., Coresh, J., Eckfeldt, J. H., Inker, L. A., Kimmel, P. L., Kusek, J. W., Liu, K. D., Mifflin, T. E., Molitch, M. E., Nelsestuen, G. L., Rebholz, C. M., Rovin, B. H., Sabbisetti, V. S., Van Eyk, J. E. & 67 others, Vasan, R. S., Waikar, S. S., Whitehead, K. M., Nelson, R. G., Ramachandran, V. S., Bonventre, J., Waikar, S., Sabbisetti, V., Van Eyk, J., Fu, Q., Brunner, H., D’Agati, V., Barasch, J., Coresh, J., Rebholz, C. M., Go, A. S., Böttinger, E., Teixeira, A., Daehn, I., Molitch, M., Batlle, D., Rovin, B., Wu, H., Levey, A. S., Inker, L. A., Foster, M. C., Hsu, C. Y., Liu, K., Klein, J., Mauer, M., Nelsestuen, G., Eckfeldt, J. H., Karger, A., Fioretto, P., Feldman, H. I., Ballard, S., Whitehead, K., Xie, D., Zhang, X., Ryan, K., Mifflin, T. E., Nelson, R. G., Fufaa, G. D., Knowler, W. C., Hanson, R. L., Jennifer Weil, E., Kimmel, P. L., Kusek, J. W., Molitoris, B., Abrahamowicz, M., Agus, D., Anderson, L., Breyer, M., Clopton, P., Foulkes, A., Goodsaid, F., Hewitt, S., Kopp, J., Lemley, K., Maisel, A., Nierras, M., Phillips, T. M., Ransohoff, D., Rule, A., Skates, S., Thompson, A. & Wright, E., Jan 1 2015, In : Clinical Journal of the American Society of Nephrology. 10, 5, p. 894-902 9 p.

Research output: Contribution to journalArticle

Biomarkers
Research
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Feasibility Studies
Quality Control
10 Citations (Scopus)

Differential gene expression in diabetic nephropathy in individuals with type 1 diabetes

Caramori, M. L., Kim, Y., Goldfine, A. B., Moore, J. H., Rich, S. S., Mychaleckyj, J. C., Kirkpatrick, D., Nickerson, H., Krolewski, A. S. & Mauer, M., Jun 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 6, p. E872-E876

Research output: Contribution to journalArticle

Diabetic Nephropathies
Medical problems
Type 1 Diabetes Mellitus
Gene expression
Gene Expression
6 Citations (Scopus)

Differential response to high glucose in skin fibroblasts of monozygotic twins discordant for type 1 diabetes

Caramori, M. L., Kim, Y., Natarajan, R., Moore, J. H., Rich, S. S., Mychaleckyj, J. C., Kuriyama, R., Kirkpatrick, D. & Mauer, M., Jun 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 6, p. E883-E889

Research output: Contribution to journalArticle

Monozygotic Twins
Fibroblasts
Medical problems
Type 1 Diabetes Mellitus
Skin
11 Citations (Scopus)

Glomerular structural-functional relationship models of diabetic nephropathy are robust in type 1 diabetic patients

Mauer, M., Caramori, L., Fioretto, P. & Najafian, B., Jun 1 2015, In : Nephrology Dialysis Transplantation. 30, 6, p. 918-923 6 p.

Research output: Contribution to journalArticle

Diabetic Nephropathies
Albumins
Glomerular Filtration Rate
Regression Analysis
Linear Models
3 Citations (Scopus)
Podocytes
Diabetic Nephropathies
Proteinuria
Blood Pressure
Glomerular Basement Membrane
13 Citations (Scopus)

Urinary monocyte chemoattractant protein-1 and hepcidin and early diabetic nephropathy lesions in type 1 diabetes mellitus

Fufaa, G. D., Weil, E. J., Nelson, R. G., Hanson, R. L., Knowler, W. C., Rovin, B. H., Wu, H., Klein, J. B., Mifflin, T. E., Feldman, H. I., Vasan, R. S., Kimmel, P. L., Kusek, J. W., Mauer, M., Zinman, B., Donnelly, S., Gardiner, R., Suissa, S., Drummond, K., Goodyer, P. & 8 others, Sinaiko, A., Strand, T., Gubler, M. C., Klein, R., CKD Biomarkers Consortium and the RASS Investigators, CKD Biomarkers Consortium and the RASS Investigators, CKD Biomarkers Consortium and the RASS Investigators & CKD Biomarkers Consortium and the RASS Investigators, Apr 1 2015, In : Nephrology Dialysis Transplantation. 30, 4, p. 599-606 8 p.

Research output: Contribution to journalArticle

Hepcidins
Chemokine CCL2
Diabetic Nephropathies
Type 1 Diabetes Mellitus
Glomerular Filtration Rate