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2016
12 Citations (Scopus)
Exome
Fasting
Atherosclerosis
Software
Genome
5 Citations (Scopus)

On Sample Size and Power Calculation for Variant Set-Based Association Tests

Wu, B. & Pankow, J., Mar 1 2016, In : Annals of Human Genetics. 80, 2, p. 136-143 8 p.

Research output: Contribution to journalArticle

Sample Size
Exome
Genome
7 Citations (Scopus)

Parathyroid hormone and the risk of incident hypertension: The Atherosclerosis Risk in Communities study

Yao, L., Folsom, A. R., Pankow, J. S., Selvin, E., Michos, E. D., Alonso, A., Tang, W. & Lutsey, P. L., Feb 1 2016, In : Journal of hypertension. 34, 2, p. 196-203 8 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Atherosclerosis
Hypertension
Demography
Chymosin
2 Citations (Scopus)

Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study

Reis, J. P., Selvin, E., Pankow, J. S., Michos, E. D., Rebholz, C. M. & Lutsey, P. L., Jun 1 2016, In : Diabetes and Metabolism. 42, 3, p. 162-169 8 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Atherosclerosis
hydroquinone
Insulin Resistance
Life Style
7 Citations (Scopus)

Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study

Florido, R., Zhao, D., Ndumele, C. E., Lutsey, P. L., Mcevoy, J. W., Windham, B. G., Pankow, J. S., Guallar, E. & Michos, E. D., Sep 2016, In : Journal of the American Heart Association. 5, 9, e003505.

Research output: Contribution to journalArticle

Coronary Disease
Atherosclerosis
Cardiovascular Diseases
Exercise
Proportional Hazards Models
21 Citations (Scopus)

Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study

Loehr, L. R., Meyer, M. L., Poon, A. K., Selvin, E., Palta, P., Tanaka, H., Pankow, J. S., Wright, J. D., Griswold, M. E., Wagenknecht, L. E. & Heiss, G., Sep 1 2016, In : American journal of hypertension. 29, 9, p. 1038-1045 8 p.

Research output: Contribution to journalArticle

Prediabetic State
Vascular Stiffness
Atherosclerosis
Glucose
Thigh
4 Citations (Scopus)

Prospective study of γ′ fibrinogen and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)

Folsom, A. R., Tang, W., George, K. M., Heckbert, S. R., MacLehose, R. F., Cushman, M. & Pankow, J. S., Mar 1 2016, In : Thrombosis Research. 139, p. 44-49 6 p.

Research output: Contribution to journalArticle

Thromboembolism
Venous Thromboembolism
Fibrinogen
Prospective Studies
African Americans
1 Citation (Scopus)

Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project

Kan, M., Auer, P. L., Wang, G. T., Bucasas, K. L., Hooker, S., Rodriguez, A., Li, B., Ellis, J., Adrienne Cupples, L., Ida Chen, Y. D., Dupuis, J., Fox, C. S., Gross, M. D., Smith, J. D., Heard-Costa, N., Meigs, J. B., Pankow, J. S., Rotter, J. I., Siscovick, D., Wilson, J. G. & 17 others, Shendure, J., Jackson, R., Peters, U., Zhong, H., Lin, D., Hsu, L., Franceschini, N., Carlson, C., Abecasis, G., Gabriel, S., Bamshad, M. J., Altshuler, D., Nickerson, D. A., North, K. E., Lange, L. A., Reiner, A. P. & Leal, S. M., Aug 1 2016, In : European Journal of Human Genetics. 24, 8, p. 1181-1187 7 p.

Research output: Contribution to journalArticle

Exome
National Heart, Lung, and Blood Institute (U.S.)
Waist-Hip Ratio
African Americans
I-kappa B Kinase
10 Citations (Scopus)

Replication of a genetic risk score for venous thromboembolism in whites but not in African Americans

Folsom, A. R., Tang, W., Weng, L. C., Roetker, N. S., Cushman, M., Basu, S. & Pankow, J. S., Jan 1 2016, In : Journal of Thrombosis and Haemostasis. 14, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

Venous Thromboembolism
African Americans
Single Nucleotide Polymorphism
Confidence Intervals
Alleles
20 Citations (Scopus)

Sequence Kernel Association Test of Multiple Continuous Phenotypes

Wu, B. & Pankow, J. S., Feb 1 2016, In : Genetic epidemiology. 40, 2, p. 91-100 10 p.

Research output: Contribution to journalArticle

Phenotype
Exome
Atherosclerosis
Genes
12 Citations (Scopus)

Serum calcium and incident type 2 diabetes: The Atherosclerosis Risk in Communities (ARIC) study

Rooney, M. R., Pankow, J. S., Sibley, S. D., Selvin, E., Reis, J. P., Michos, E. D. & Lutsey, P. L., Oct 1 2016, In : American Journal of Clinical Nutrition. 104, 4, p. 1023-1029 7 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Atherosclerosis
Calcium
Serum
Calcium-Sensing Receptors
12 Citations (Scopus)

Serum fibroblast growth factor-23 and incident hypertension: The Atherosclerosis Risk in Communities (ARIC) Study

Fyfe-Johnson, A. L., Alonso, A., Selvin, E., Bower, J. K., Pankow, J. S., Agarwal, S. K. & Lutsey, P. L., Jul 1 2016, In : Journal of hypertension. 34, 7, p. 1266-1272 7 p.

Research output: Contribution to journalArticle

Atherosclerosis
Hypertension
Serum
fibroblast growth factor 23
Confidence Intervals
27 Citations (Scopus)

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

Liu, C. T., Raghavan, S., Maruthur, N., Kabagambe, E. K., Hong, J., Ng, M. C. Y., Hivert, M. F., Lu, Y., An, P., Bentley, A. R., Drolet, A. M., Gaulton, K. J., Guo, X., Armstrong, L. L., Irvin, M. R., Li, M., Lipovich, L., Rybin, D. V., Taylor, K. D., Agyemang, C. & 95 others, Palmer, N. D., Cade, B. E., Chen, W. M., Dauriz, M., Delaney, J. A. C., Edwards, T. L., Evans, D. S., Evans, M. K., Lange, L. A., Leong, A., Liu, J., Liu, Y., Nayak, U., Patel, S. R., Porneala, B. C., Rasmussen-Torvik, L. J., Snijder, M. B., Stallings, S. C., Tanaka, T., Yanek, L. R., Zhao, W., Becker, D. M., Bielak, L. F., Biggs, M. L., Bottinger, E. P., Bowden, D. W., Chen, G., Correa, A., Couper, D. J., Crawford, D. C., Cushman, M., Eicher, J. D., Fornage, M., Franceschini, N., Fu, Y. P., Goodarzi, M. O., Gottesman, O., Hara, K., Harris, T. B., Jensen, R. A., Johnson, A. D., Jhun, M. A., Karter, A. J., Keller, M. F., Kho, A. N., Kizer, J. R., Krauss, R. M., Langefeld, C. D., Li, X., Liang, J., Liu, S., Lowe, W. L., Mosley, T. H., North, K. E., Pacheco, J. A., Peyser, P. A., Patrick, A. L., Rice, K. M., Selvin, E., Sims, M., Smith, J. A., Tajuddin, S. M., Vaidya, D., Wren, M. P., Yao, J., Zhu, X., Ziegler, J. T., Zmuda, J. M., Zonderman, A. B., Zwinderman, A. H., Adeyemo, A., Boerwinkle, E., Ferrucci, L., Hayes, M. G., Kardia, S. L. R., Miljkovic, I., Pankow, J. S., Rotimi, C. N., Sale, M. M., Wagenknecht, L. E., Arnett, D. K., Chen, Y. D. I., Nalls, M. A., Province, M. A., Kao, W. H. L., Siscovick, D. S., Psaty, B. M., Wilson, J. G., Loos, R. J. F., Dupuis, J., Rich, S. S., Florez, J. C., Rotter, J. I., Morris, A. P. & Meigs, J. B., Jul 7 2016, In : American Journal of Human Genetics. 99, 1, p. 56-75 20 p.

Research output: Contribution to journalArticle

Meta-Analysis
Fasting
Insulin
Glucose
Type 2 Diabetes Mellitus
20 Citations (Scopus)

USAT: A Unified Score-Based Association Test for Multiple Phenotype-Genotype Analysis

Ray, D., Pankow, J. & Basu, S., Jan 1 2016, In : Genetic epidemiology. 40, 1, p. 20-34 15 p.

Research output: Contribution to journalArticle

Multivariate Analysis
Analysis of Variance
Genotype
Phenotype
Genome-Wide Association Study
1 Citation (Scopus)

Walking and calcified atherosclerotic plaque in the coronary arteries

Imran, T. F., Patel, Y., Ellison, R. C., Carr, J. J., Arnett, D. K., Pankow, J. S., Heiss, G., Hunt, S. C., Gaziano, J. M. & Djoussé, L., Jun 1 2016, In : Arteriosclerosis, thrombosis, and vascular biology. 36, 6, p. 1272-1277 6 p.

Research output: Contribution to journalArticle

Atherosclerotic Plaques
Walking
Coronary Vessels
Confidence Intervals
Metabolic Equivalent
2015
26 Citations (Scopus)
Vitamin D-Binding Protein
Coronary Disease
Carrier Proteins
Genes
Single Nucleotide Polymorphism
3 Citations (Scopus)

A Bayesian partitioning model for the detection of multilocus effects in case-control studies

Ray, D., Li, X., Pan, W., Pankow, J. & Basu, S., Jul 22 2015, In : Human Heredity. 79, 2, p. 69-79 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Case-Control Studies
Type 2 Diabetes Mellitus
Single Nucleotide Polymorphism
Atherosclerosis
3 Citations (Scopus)

A genetic association study of activated partial thromboplastin time in European Americans and African Americans: The ARIC Study

Weng, L. C., Cushman, M., Pankow, J. S., Basu, S., Boerwinkle, E., Folsom, A. R. & Tang, W., Apr 15 2015, In : Human molecular genetics. 24, 8, p. 2401-2408 8 p., ddu732.

Research output: Contribution to journalArticle

Partial Thromboplastin Time
Genetic Association Studies
African Americans
Atherosclerosis
Genes
24 Citations (Scopus)

Association of ideal cardiovascular health and calcified atherosclerotic plaque in the coronary arteries: The National Heart, Lung, and Blood Institute Family Heart Study

Robbins, J. M., Petrone, A. B., Carr, J. J., Pankow, J. S., Hunt, S. C., Heiss, G., Arnett, D. K., Ellison, R. C., Gaziano, J. M. & Djoussé, L., Mar 1 2015, In : American Heart Journal. 169, 3, p. 371-378.e1

Research output: Contribution to journalArticle

National Heart, Lung, and Blood Institute (U.S.)
Atherosclerotic Plaques
Coronary Vessels
Calcium
Health
30 Citations (Scopus)

Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: A meta-analysis of 50,345 Caucasians

Fretts, A. M., Follis, J. L., Nettleton, J. A., Lemaitre, R. N., Ngwa, J. S., Wojczynski, M. K., Kalafati, I. P., Varga, T. V., Frazier-Wood, A. C., Houston, D. K., Lahti, J., Ericson, U., Van Den Hooven, E. H., Mikkilä, V., Kiefte-De Jong, J. C., Mozaffarian, D., Rice, K., Renström, F., North, K. E., McKeown, N. M. & 42 others, Feitosa, M. F., Kanoni, S., Smith, C. E., Garcia, M. E., Tiainen, A. M., Sonestedt, E., Manichaikul, A., Van Rooij, F. J. A., Dimitriou, M., Raitakari, O., Pankow, J. S., Djoussé, L., Province, M. A., Hu, F. B., Lai, C. Q., Keller, M. F., Perälä, M. M., Rotter, J. I., Hofman, A., Graff, M., Kähönen, M., Mukamal, K., Johansson, I., Ordovas, J. M., Liu, Y., Männistö, S., Uitterlinden, A. G., Deloukas, P., Seppälä, I., Psaty, B. M., Cupples, L. A., Borecki, I. B., Franks, P. W., Arnett, D. K., Nalls, M. A., Eriksson, J. G., Orho-Melander, M., Franco, O. H., Lehtimäki, T., Dedoussis, G. V., Meigs, J. B. & Siscovick, D. S., Nov 1 2015, In : American Journal of Clinical Nutrition. 102, 5, p. 1266-1278 13 p.

Research output: Contribution to journalArticle

Meat
Meta-Analysis
Fasting
Insulin
Glucose
72 Citations (Scopus)

Directional dominance on stature and cognition in diverse human populations

Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V., Trompet, S. & 339 others, Guo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Traglia, M., Farmaki, A. E., Kacprowski, T., Bjonnes, A., Van Der Spek, A., Wu, Y., Giri, A. K., Yanek, L. R., Wang, L., Hofer, E., Rietveld, C. A., McLeod, O., Cornelis, M. C., Pattaro, C., Verweij, N., Baumbach, C., Abdellaoui, A., Warren, H. R., Vuckovic, D., Mei, H., Bouchard, C., Perry, J. R. B., Cappellani, S., Mirza, S. S., Benton, M. C., Broeckel, U., Medland, S. E., Lind, P. A., Malerba, G., Drong, A., Yengo, L., Bielak, L. F., Zhi, D., Van Der Most, P. J., Shriner, D., Mägi, R., Hemani, G., Karaderi, T., Wang, Z., Liu, T., Demuth, I., Zhao, J. H., Meng, W., Lataniotis, L., Van Der Laan, S. W., Bradfield, J. P., Wood, A. R., Bonnefond, A., Ahluwalia, T. S., Hall, L. M., Salvi, E., Yazar, S., Carstensen, L., De Haan, H. G., Abney, M., Afzal, U., Allison, M. A., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Barr, R. G., Baumeister, S. E., Benjamin, D. J., Bergmann, S., Boerwinkle, E., Bottinger, E. P., Campbell, A., Chakravarti, A., Chan, Y., Chanock, S. J., Chen, C., Chen, Y. D. I., Collins, F. S., Connell, J., Correa, A., Cupples, L. A., Smith, G. D., Davies, G., Dörr, M., Ehret, G., Ellis, S. B., Feenstra, B., Feitosa, M. F., Ford, I., Fox, C. S., Frayling, T. M., Friedrich, N., Geller, F., Scotland, G., Gillham-Nasenya, I., Gottesman, O., Graff, M., Grodstein, F., Gu, C., Haley, C., Hammond, C. J., Harris, S. E., Harris, T. B., Hastie, N. D., Heard-Costa, N. L., Heikkilä, K., Hocking, L. J., Homuth, G., Hottenga, J. J., Huang, J., Huffman, J. E., Hysi, P. G., Ikram, M. A., Ingelsson, E., Joensuu, A., Johansson, Å., Jousilahti, P., Jukema, J. W., Kähönen, M., Kamatani, Y., Kanoni, S., Kerr, S. M., Khan, N. M., Koellinger, P., Koistinen, H. A., Kooner, M. K., Kubo, M., Kuusisto, J., Lahti, J., Launer, L. J., Lea, R. A., Lehne, B., Lehtimäki, T., Liewald, D. C. M., Lind, L., Loh, M., Lokki, M. L., London, S. J., Loomis, S. J., Loukola, A., Lu, Y., Lumley, T., Lundqvist, A., Männistö, S., Marques-Vidal, P., Masciullo, C., Matchan, A., Mathias, R. A., Matsuda, K., Meigs, J. B., Meisinger, C., Meitinger, T., Menni, C., Mentch, F. D., Mihailov, E., Milani, L., Montasser, M. E., Montgomery, G. W., Morrison, A., Myers, R. H., Nadukuru, R., Navarro, P., Nalis, M., Nieminen, M. S., Nolte, I. M., O'Connor, G. T., Ogunniyi, A., Padmanabhan, S., Palmas, W. R., Pankow, J. S., Patarcic, I., Pavani, F., Peyser, P. A., Pietilainen, K., Poulter, N., Prokopenko, I., Ralhan, S., Redmond, P., Rich, S. S., Rissanen, H., Robino, A., Rose, L. M., Rose, R., Sala, C., Salako, B., Salomaa, V., Sarin, A. P., Saxena, R., Schmidt, H., Scott, L. J., Scott, W. R., Sennblad, B., Seshadri, S., Sever, P., Shrestha, S., Smith, B. H., Smith, J. A., Soranzo, N., Sotoodehnia, N., Southam, L., Stanton, A. V., Stathopoulou, M. G., Strauch, K., Strawbridge, R. J., Suderman, M. J., Tandon, N., Tang, S. T., Taylor, K. D., Tayo, B. O., Töglhofer, A. M., Tomaszewski, M., Tšernikova, N., Tuomilehto, J., Uitterlinden, A. G., Vaidya, D., Van Hylckama Vlieg, A., Van Setten, J., Vasankari, T., Vedantam, S., Vlachopoulou, E., Vozzi, D., Vuoksimaa, E., Waldenberger, M., Ware, E. B., Wentworth-Shields, W., Whitfield, J. B., Wild, S., Willemsen, G., Yajnik, C. S., Yao, J., Zaza, G., Zhu, X., Salem, R. M., Melbye, M., Bisgaard, H., Samani, N. J., Cusi, D., Mackey, D. A., Cooper, R. S., Froguel, P., Pasterkamp, G., Grant, S. F. A., Hakonarson, H., Ferrucci, L., Scott, R. A., Morris, A. D., Palmer, C. N. A., Dedoussis, G., Deloukas, P., Bertram, L., Lindenberger, U., Berndt, S. I., Lindgren, C. M., Timpson, N. J., Tönjes, A., Munroe, P. B., Sørensen, T. I. A., Rotimi, C. N., Arnett, D. K., Oldehinkel, A. J., Kardia, S. L. R., Balkau, B., Gambaro, G., Morris, A. P., Eriksson, J. G., Wright, M. J., Martin, N. G., Hunt, S. C., Starr, J. M., Deary, I. J., Griffiths, L. R., Tiemeier, H., Pirastu, N., Kaprio, J., Wareham, N. J., Pérusse, L., Wilson, J. G., Girotto, G., Caulfield, M. J., Raitakari, O., Boomsma, D. I., Gieger, C., Van Der Harst, P., Hicks, A. A., Kraft, P., Sinisalo, J., Knekt, P., Johannesson, M., Magnusson, P. K. E., Hamsten, A., Schmidt, R., Borecki, I. B., Vartiainen, E., Becker, D. M., Bharadwaj, D., Mohlke, K. L., Boehnke, M., Van Duijn, C. M., Sanghera, D. K., Teumer, A., Zeggini, E., Metspalu, A., Gasparini, P., Ulivi, S., Ober, C., Toniolo, D., Rudan, I., Porteous, D. J., Ciullo, M., Spector, T. D., Hayward, C., Dupuis, J., Loos, R. J. F., Wright, A. F., Chandak, G. R., Vollenweider, P., Shuldiner, A. R., Ridker, P. M., Rotter, J. I., Sattar, N., Gyllensten, U., North, K. E., Pirastu, M., Psaty, B. M., Weir, D. R., Laakso, M., Gudnason, V., Takahashi, A., Chambers, J. C., Kooner, J. S., Strachan, D. P., Campbell, H., Hirschhorn, J. N., Perola, M., Polašek, O. & Wilson, J. F., Jul 23 2015, In : Nature. 523, 7561, p. 459-462 4 p.

Research output: Contribution to journalArticle

Cognition
Genome
Population
Aptitude
Inbreeding
142 Citations (Scopus)

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

Demerath, E. W., Guan, W., Grove, M. L., Aslibekyan, S., Mendelson, M., Zhou, Y. H., Hedman, Å. K., Sandling, J. K., Li, L. A., Irvin, M. R., Zhi, D., Deloukas, P., Liang, L., Liu, C., Bressler, J., Spector, T. D., North, K., Li, Y., Absher, D. M., Levy, D. & 4 others, Arnett, D. K., Fornage, M., Pankow, J. S. & Boerwinkle, E., Aug 1 2015, In : Human molecular genetics. 24, 15, p. 4464-4479 16 p.

Research output: Contribution to journalArticle

Waist Circumference
African Americans
Body Mass Index
DNA Methylation
DNA
69 Citations (Scopus)

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

Aslibekyan, S., Demerath, E. W., Mendelson, M., Zhi, D., Guan, W., Liang, L., Sha, J., Pankow, J. S., Liu, C., Irvin, M. R., Fornage, M., Hidalgo, B., Lin, L. A., Stanton Thibeault, K., Bressler, J., Tsai, M. Y., Grove, M. L., Hopkins, P. N., Boerwinkle, E., Borecki, I. B. & 5 others, Ordovas, J. M., Levy, D., Tiwari, H. K., Absher, D. M. & Arnett, D. K., Jul 1 2015, In : Obesity. 23, 7, p. 1493-1501 9 p.

Research output: Contribution to journalArticle

Waist Circumference
Methylation
Body Mass Index
Cytosine
Guanine
42 Citations (Scopus)

Fructosamine and glycated albumin and the risk of cardiovascular outcomes and death

Selvin, E., Rawlings, A. M., Lutsey, P. L., Maruthur, N., Pankow, J. S., Steffes, M. & Coresh, J., Jul 28 2015, In : Circulation. 132, 4, p. 269-277 9 p.

Research output: Contribution to journalArticle

Fructosamine
Hemoglobins
Coronary Disease
Diabetes Mellitus
Heart Failure
6 Citations (Scopus)

Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans

Tang, W., Cushman, M., Green, D., Rich, S. S., Lange, L. A., Yang, Q., Tracy, R. P., Tofler, G. H., Basu, S., Wilson, J. G., Keating, B. J., Weng, L. C., Taylor, H. A., Jacobs, D. R., Delaney, J. A., Palmer, C. D., Young, T., Pankow, J. S., O'Donnell, C. J., Smith, N. L. & 2 others, Reiner, A. P. & Folsom, A. R., Jun 1 2015, In : American Journal of Hematology. 90, 6, p. 534-540 7 p.

Research output: Contribution to journalArticle

von Willebrand Factor
African Americans
Coagulants
Genes
Single Nucleotide Polymorphism
183 Citations (Scopus)

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Mägi, R., Reschen, M. E., Mahajan, A., Locke, A., Rayner, N. W., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Frånberg, M. & 198 others, Strawbridge, R. J., Kestler, H., Chheda, H., Eisele, L., Gustafsson, S., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Karssen, L. C., Van Leeuwen, E. M., Willems, S. M., Li, M., Chen, H., Fuchsberger, C., Kwan, P., Ma, C., Linderman, M., Lu, Y., Thomsen, S. K., Rundle, J. K., Beer, N. L., Van De Bunt, M., Chalisey, A., Kang, H. M., Voight, B. F., Abecasis, G. R., Almgren, P., Baldassarre, D., Balkau, B., Benediktsson, R., Blüher, M., Boeing, H., Bonnycastle, L. L., Bottinger, E. P., Burtt, N. P., Carey, J., Charpentier, G., Chines, P. S., Cornelis, M. C., Couper, D. J., Crenshaw, A. T., Van Dam, R. M., Doney, A. S. F., Dorkhan, M., Edkins, S., Eriksson, J. G., Esko, T., Eury, E., Fadista, J., Flannick, J., Fontanillas, P., Fox, C., Franks, P. W., Gertow, K., Gieger, C., Gigante, B., Gottesman, O., Grant, G. B., Grarup, N., Groves, C. J., Hassinen, M., Have, C. T., Herder, C., Holmen, O. L., Hreidarsson, A. B., Humphries, S. E., Hunter, D. J., Jackson, A. U., Jonsson, A., Jørgensen, M. E., Jørgensen, T., Kao, W. H. L., Kerrison, N. D., Kinnunen, L., Klopp, N., Kong, A., Kovacs, P., Kraft, P., Kravic, J., Langford, C., Leander, K., Liang, L., Lichtner, P., Lindgren, C. M., Lindholm, E., Linneberg, A., Liu, C. T., Lobbens, S., Luan, J., Lyssenko, V., Männistö, S., McLeod, O., Meyer, J., Mihailov, E., Mirza, G., Mühleisen, T. W., Müller-Nurasyid, M., Navarro, C., Nöthen, M. M., Oskolkov, N. N., Owen, K. R., Palli, D., Pechlivanis, S., Peltonen, L., Perry, J. R. B., Platou, C. G. P., Roden, M., Ruderfer, D., Rybin, D., Van Der Schouw, Y. T., Sennblad, B., Sigurosson, G., Stančáková, A., Steinbach, G., Storm, P., Strauch, K., Stringham, H. M., Sun, Q., Thorand, B., Tikkanen, E., Tonjes, A., Trakalo, J., Tremoli, E., Tuomi, T., Wennauer, R., Wiltshire, S., Wood, A. R., Zeggini, E., Dunham, I., Birney, E., Pasquali, L., Ferrer, J., Loos, R. J. F., Dupuis, J., Florez, J. C., Boerwinkle, E., Pankow, J. S., Van Duijn, C., Sijbrands, E., Meigs, J. B., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Lakka, T. A., Rauramaa, R., Stumvoll, M., Pedersen, N. L., Lind, L., Keinanen-Kiukaanniemi, S. M., Korpi-Hyövälti, E., Saaristo, T. E., Saltevo, J., Kuusisto, J., Laakso, M., Metspalu, A., Erbel, R., Jöckel, K. H., Moebus, S., Ripatti, S., Salomaa, V., Ingelsson, E., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Koistinen, H., Tuomilehto, J., Hveem, K., Njølstad, I., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., De Faire, U., Hamsten, A., Illig, T., Peters, A., Cauchi, S., Sladek, R., Froguel, P., Hansen, T., Pedersen, O., Morris, A. D., Palmer, C. N. A., Kathiresan, S., Melander, O., Nilsson, P. M., Groop, L. C., Barroso, I., Langenberg, C., Wareham, N. J., O'Callaghan, C. A., Gloyn, A. L., Altshuler, D., Boehnke, M., Teslovich, T. M., McCarthy, M. I. & Morris, A. P., Dec 1 2015, In : Nature Genetics. 47, 12, p. 1415-1425 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Alleles
Islets of Langerhans
Chromatin Immunoprecipitation
Liver
15 Citations (Scopus)

Genetics of Plasma soluble Receptor for Advanced Glycation End-products and cardiovascular outcomes in a community-based population: Results from the Atherosclerosis Risk in Communities Study

Maruthur, N. M., Li, M., Halushka, M. K., Astor, B. C., Pankow, J. S., Boerwinkle, E., Coresh, J., Selvin, E. & Linda Kao, W. H., Jun 17 2015, In : PloS one. 10, 6, e0128452.

Research output: Contribution to journalArticle

atherosclerosis
Atherosclerosis
Plasmas
receptors
Population
41 Citations (Scopus)

Genetic variants associated with quantitative glucose homeostasis traits translate to type 2 diabetes in Mexican Americans: The GUARDIAN (Genetics underlying diabetes in Hispanics) consortium

Palmer, N. D., Goodarzi, M. O., Langefeld, C. D., Wang, N., Guo, X., Taylor, K. D., Fingerlin, T. E., Norris, J. M., Buchanan, T. A., Xiang, A. H., Haritunians, T., Ziegler, J. T., Williams, A. H., Stefanovski, D., Cui, J., Mackay, A. W., Henkin, L. F., Bergman, R. N., Gao, X., Gauderman, J. & 29 others, Varma, R., Hanis, C. L., Cox, N. J., Highland, H. M., Below, J. E., Williams, A. L., Burtt, N. P., Aguilar-Salinas, C. A., Huerta-Chagoya, A., Gonzalez-Villalpando, C., Orozco, L., Haiman, C. A., Tsai, M. Y., Johnson, W. C., Yao, J., Rasmussen-Torvik, L., Pankow, J., Snively, B., Jackson, R. D., Liu, S., Nadler, J. L., Kandeel, F., Chen, Y. D. I., Bowden, D. W., Rich, S. S., Raffel, L. J., Rotter, J. I., Watanabe, R. M. & Wagenknecht, L. E., May 2015, In : Diabetes. 64, 5, p. 1853-1866 14 p.

Research output: Contribution to journalArticle

Hispanic Americans
Type 2 Diabetes Mellitus
Homeostasis
Glucose
Insulin
5 Citations (Scopus)

Geospatial patterns of human papillomavirus vaccine uptake in Minnesota

Nelson, E. J., Hughes, J., Oakes, J. M., Pankow, J. S. & Kulasingam, S. L., Jan 1 2015, In : BMJ open. 5, 8, e008617.

Research output: Contribution to journalArticle

Papillomavirus Vaccines
Vaccination
Vaccines
Spatial Analysis
Statistical Models
13 Citations (Scopus)

Human Papillomavirus Infection in Women Who Submit Self-collected Vaginal Swabs After Internet Recruitment

Nelson, E. J., Hughes, J., Oakes, J. M., Thyagarajan, B., Pankow, J. S. & Kulasingam, S. L., Jun 1 2015, In : Journal of Community Health. 40, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

Papillomavirus Infections
Internet
online survey
Postal Service
Uterine Cervical Neoplasms
36 Citations (Scopus)

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

Knowles, J. W., Xie, W., Zhang, Z., Chennemsetty, I., Assimes, T. L., Paananen, J., Hansson, O., Pankow, J., Goodarzi, M. O., Carcamo-Orive, I., Morris, A. P., Chen, Y. D. I., Mäkinen, V. P., Ganna, A., Mahajan, A., Guo, X., Abbasi, F., Greenawalt, D. M., Lum, P., Molony, C. & 19 others, Lind, L., Lindgren, C., Raffel, L. J., Tsao, P. S., Schadt, E. E., Rotter, J. I., Sinaiko, A., Reaven, G., Yang, X., Hsiung, C. A., Groop, L., Cordell, H. J., Laakso, M., Hao, K., Ingelsson, E., Frayling, T. M., Weedon, M. N., Walker, M. & Quertermous, T., Apr 1 2015, In : Journal of Clinical Investigation. 125, 4, p. 1739-1751 13 p.

Research output: Contribution to journalArticle

Acetyltransferases
Insulin Resistance
Genes
Insulin
hydrazine
3 Citations (Scopus)

Lack of association of apolipoprotein E (Apo E) polymorphism with the prevalence of metabolic syndrome: The National Heart, Lung and Blood Institute Family Heart Study

Lai, L. Y. H., Petrone, A. B., Pankow, J. S., Arnett, D. K., North, K. E., Ellison, R. C., Hunt, S. C., Rosenzweig, J. L. & Djoussé, L., Sep 1 2015, In : Diabetes/Metabolism Research and Reviews. 31, 6, p. 582-587 6 p.

Research output: Contribution to journalArticle

National Heart, Lung, and Blood Institute (U.S.)
Apolipoproteins E
Genotype
Odds Ratio
Confidence Intervals
94 Citations (Scopus)

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M. F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 184 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Stoiber, M. H., Strawbridge, R. J., Taylor, K. D., Varga, T. V., Allin, K. H., Amin, N., Aponte, J. L., Aung, T., Barbieri, C., Bihlmeyer, N. A., Boehnke, M., Bombieri, C., Bowden, D. W., Burns, S. M., Chen, Y., Chen, Y. D., Cheng, C. Y., Correa, A., Czajkowski, J., Dehghan, A., Ehret, G. B., Eiriksdottir, G., Escher, S. A., Farmaki, A. E., Frånberg, M., Gambaro, G., Giulianini, F., Goddard, W. A., Goel, A., Gottesman, O., Grove, M. L., Gustafsson, S., Hai, Y., Hallmans, G., Heo, J., Hoffmann, P., Ikram, M. K., Jensen, R. A., Jørgensen, M. E., Jørgensen, T., Karaleftheri, M., Khor, C. C., Kirkpatrick, A., Kraja, A. T., Kuusisto, J., Lange, E. M., Lee, I. T., Lee, W. J., Leong, A., Liao, J., Liu, C., Liu, Y., Lindgren, C. M., Linneberg, A., Malerba, G., Mamakou, V., Marouli, E., Maruthur, N. M., Matchan, A., McKean-Cowdin, R., McLeod, O., Metcalf, G. A., Mohlke, K. L., Muzny, D. M., Ntalla, I., Palmer, N. D., Pasko, D., Peter, A., Rayner, N. W., Renström, F., Rice, K., Sala, C. F., Sennblad, B., Serafetinidis, I., Smith, J. A., Soranzo, N., Speliotes, E. K., Stahl, E. A., Stirrups, K., Tentolouris, N., Thanopoulou, A., Torres, M., Traglia, M., Tsafantakis, E., Javad, S., Yanek, L. R., Zengini, E., Becker, D. M., Bis, J. C., Brown, J. B., Adrienne Cupples, L., Hansen, T., Ingelsson, E., Karter, A. J., Lorenzo, C., Mathias, R. A., Norris, J. M., Peloso, G. M., Sheu, W. H. H., Toniolo, D., Vaidya, D., Varma, R., Wagenknecht, L. E., Boeing, H., Bottinger, E. P., Dedoussis, G., Deloukas, P., Ferrannini, E., Franco, O. H., Franks, P. W., Gibbs, R. A., Gudnason, V., Hamsten, A., Harris, T. B., Hattersley, A. T., Hayward, C., Hofman, A., Jansson, J. H., Langenberg, C., Launer, L. J., Levy, D., Oostra, B. A., O'Donnell, C. J., O'Rahilly, S., Padmanabhan, S., Pankow, J. S., Polasek, O., Province, M. A., Rich, S. S., Ridker, P. M., Rudan, I., Schulze, M. B., Smith, B. H., Uitterlinden, A. G., Walker, M., Watkins, H., Wong, T. Y., Zeggini, E., Laakso, M., Borecki, I. B., Chasman, D. I., Pedersen, O., Psaty, B. M., Shyong Tai, E., Van Duijn, C. M., Wareham, N. J., Waterworth, D. M., Boerwinkle, E., Linda Kao, W. H., Florez, J. C., Loos, R. J. F., Wilson, J. G., Frayling, T. M., Siscovick, D. S., Dupuis, J., Rotter, J. I., Meigs, J. B., Scott, R. A. & Goodarzi, M. O., Feb 2015, In : Nature communications. 6, 6897.

Research output: Contribution to journalArticle

fasting
Exome
Medical problems
glucose
Type 2 Diabetes Mellitus
7 Citations (Scopus)

Multi-ethnic analysis reveals soluble l-selectin may be post-transcriptionally regulated by 3′UTR polymorphism: the Multi-Ethnic Study of Atherosclerosis (MESA)

Berardi, C., Larson, N. B., Decker, P. A., Wassel, C. L., Kirsch, P. S., Pankow, J. S., Sale, M. M., de Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Tsai, M. Y., Chen, Y. D. I. & Bielinski, S. J., Jan 1 2015, In : Human Genetics. 134, 4, p. 393-403 11 p.

Research output: Contribution to journalArticle

Selectins
Atherosclerosis
Linear Models
Cardiovascular Diseases
African Americans
23 Citations (Scopus)

Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein

Ligthart, S., De Vries, P. S., Uitterlinden, A. G., Hofman, A., Franco, O. H., Chasman, D. I., Dehghan, A., Dupuis, J., Barbalic, M., Bis, J. C., Eiriksdottir, G., Lu, C., Pellikka, N., Wallaschofski, H., Kettunen, J., Henneman, P., Baumert, J., Strachan, D. P., Fuchsberger, C., Vitart, V. & 98 others, Wilson, J. F., Paré, G., Naitza, S., Rudock, M. E., Surakka, I., De Geus, E. J. C., Alizadeh, B. Z., Guralnik, J. M. D., Shuldiner, A., Tanaka, T., Zee, R. Y. L., Schnabel, R. B., Nambi, V., Kavousi, M., Ripatti, S., Nauck, M., Smith, N. L., Smith, A. V., Sundvall, J., Scheet, P., Liu, Y., Ruokonen, A., Rose, L. M., Larson, M. G., Hoogeveen, R. C., Freimer, N. B., Teumer, A., Tracy, R. P., Launer, L. J., Buring, J. E., Yamamoto, J. F., Folsom, A. R., Sijbrands, E. J. G., Pankow, J., Elliott, P., Keaney, J. F., Sun, W., Sarin, A. P., Fontes, J. D., Badola, S., Astor, B. C., Pouta, A., Werda, K., Greiser, K. H., Kuss, O., Schwabedissen, H. E. M. Z., Thiery, J., Jamshidi, Y., Nolte, I. M., Soranzo, N., Spector, T. D., Völzke, H., Parker, A. N., Aspelund, T., Bates, D., Young, L., Tsui, K., Siscovick, D. S., Guo, X., Rotter, J. I., Uda, M., Schlessinger, D., Rudan, I., Hicks, A. A., Penninx, B. W., Thorand, B., Gieger, C., Coresh, J., Willemsen, G., Harris, T. B., Järvelin, M. R., Rice, K., Radke, D., Salomaa, V., Van Dijk, K. W., Boerwinkle, E., Vasan, R. S., Ferrucci, L., Gibson, Q. D., Bandinelli, S., Snieder, H., Boomsma, D. I., Xiao, X., Campbell, H., Hayward, C., Pramstaller, P. P., Duijn, C. M., Peltonen, L., Psaty, B. M., Gudnason, V., Ridker, P. M., Homuth, G., Koenig, W., Ballantyne, C. M., Witteman, J. C. M., Benjamin, E. J., Perola, M. & Chasman., D. I., Mar 13 2015, In : PloS one. 10, 3, e0118859.

Research output: Contribution to journalArticle

pleiotropy
Genetic Loci
C-reactive protein
C-Reactive Protein
Phenotype
8 Citations (Scopus)

Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)

Folsom, A. R., Tang, W., Roetker, N. S., Heckbert, S. R., Cushman, M. & Pankow, J. S., Nov 2015, In : American Journal of Hematology. 90, 11, p. 1047-1051 5 p.

Research output: Contribution to journalArticle

Factor XI
Thromboembolism
Venous Thromboembolism
Prospective Studies
African Americans
45 Citations (Scopus)

Prospective study of sickle cell trait and venous thromboembolism incidence

Folsom, A. R., Tang, W., Roetker, N. S., Kshirsagar, A. V., Derebail, V. K., Lutsey, P. L., Naik, R., Pankow, J. S., Grove, M. L., Basu, S., Key, N. S. & Cushman, M., Jan 1 2015, In : Journal of Thrombosis and Haemostasis. 13, 1, p. 2-9 8 p.

Research output: Contribution to journalArticle

Sickle Cell Trait
Venous Thromboembolism
Pulmonary Embolism
Prospective Studies
Incidence
27 Citations (Scopus)

P-selectin and subclinical and clinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA)

Bielinski, S. J., Berardi, C., Decker, P. A., Kirsch, P. S., Larson, N. B., Pankow, J. S., Sale, M., de Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Wassel, C. L., Polak, J. F. & Tsai, M. Y., May 1 2015, In : Atherosclerosis. 240, 1, p. 3-9 7 p.

Research output: Contribution to journalArticle

P-Selectin
Atherosclerosis
Coronary Disease
Coronary Vessels
Calcium
21 Citations (Scopus)
Vitamin D-Binding Protein
Atherosclerosis
Carrier Proteins
Genes
Single Nucleotide Polymorphism
42 Citations (Scopus)
Vitamin D-Binding Protein
Atherosclerosis
Heart Failure
Genes
Carrier Proteins
12 Citations (Scopus)
Genes
Exome
Chi-Square Distribution
Type 2 Diabetes Mellitus
Atherosclerosis
39 Citations (Scopus)

Six-year change in high-sensitivity C-reactive protein and risk of diabetes, cardiovascular disease, and mortality

Parrinello, C. M., Lutsey, P. L., Ballantyne, C. M., Folsom, A. R., Pankow, J. S. & Selvin, E., Aug 1 2015, In : American Heart Journal. 170, 2, p. 380-389.e4

Research output: Contribution to journalArticle

C-Reactive Protein
Cardiovascular Diseases
Mortality
Heart Failure
Stroke
9 Citations (Scopus)

Soluble P-selectin predicts lower extremity peripheral artery disease incidence and change in the ankle brachial index: The Multi-Ethnic Study of Atherosclerosis (MESA)

Wassel, C. L., Berardi, C., Pankow, J. S., Larson, N. B., Decker, P. A., Hanson, N. Q., Tsai, M. Y., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2015, In : Atherosclerosis. 239, 2, p. 405-411 7 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
P-Selectin
Peripheral Arterial Disease
Lower Extremity
Atherosclerosis
8 Citations (Scopus)
Genome-Wide Association Study
Single Nucleotide Polymorphism
Atherosclerosis
Software
Logistic Models
114 Citations (Scopus)

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 36 others, Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H. J., White, C. C., Absher, D., Ahluwalia, T. S., Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Cadby, G., Cheng, Y. C., Chiang, C. W. K., Delgado, G., Demirkan, A., Dueker, N., Eklund, N., Eiriksdottir, G., Eriksson, J., Feenstra, B., Pankow, J. S., CHARGE Consortium, DIAGRAM Consortium, GLGC Consortium, Global-BPGen Consortium, ICBP Consortium & MAGIC Consortium, Jan 1 2015, In : PLoS genetics. 11, 10, p. 1-42 42 p., e1005378.

Research output: Contribution to journalArticle

body shape
Body Size
anthropometric measurements
body size
genome
4 Citations (Scopus)

Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the multi-ethnic study of atherosclerosis (MESA)

Larson, N. B., Berardi, C., Decker, P. A., Wassel, C. L., Kirsch, P. S., Pankow, J. S., Sale, M. M., de Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Tsai, M. Y., Taylor, K. D. & Bielinski, S. J., Jul 1 2015, In : Annals of Human Genetics. 79, 4, p. 264-274 11 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Meta-Analysis
Atherosclerosis
Asian Americans
Mesoderm
33 Citations (Scopus)

Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: The Atherosclerosis Risk in Communities (ARIC) study

Schneider, A. L. C., Lutsey, P. L., Selvin, E., Mosley, T. H., Sharrett, A. R., Carson, K. A., Post, W. S., Pankow, J. S., Folsom, A. R., Gottesman, R. F. & Michos, E. D., Aug 1 2015, In : European Journal of Neurology. 22, 8, p. 1220-1227 8 p.

Research output: Contribution to journalArticle

Vitamin D-Binding Protein
Vitamin D
Atherosclerosis
Stroke
Carrier Proteins