Find Research Outputs

Search concepts
Selected Filters
2017
1 Citation (Scopus)

Elevated Levels of Adhesion Proteins Are Associated with Low Ankle-Brachial Index: Multi-Ethnic Study of Atherosclerosis

Berardi, C., Wassel, C. L., Decker, P. A., Larson, N. B., Kirsch, P. S., Andrade, M. D., Tsai, M. Y., Pankow, J. S., Sale, M. M., Sicotte, H., Tang, W., Hanson, N. Q., McDermott, M. M., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2017, In : Angiology. 68, 4, p. 322-329 8 p.

Research output: Contribution to journalArticle

Open Access
Ankle Brachial Index
Atherosclerosis
Proteins
Peripheral Arterial Disease
Secretory Leukocyte Peptidase Inhibitor
32 Citations (Scopus)

Epigenome-wide association studies identify DNA methylation associated with kidney function

Chu, A. Y., Tin, A., Schlosser, P., Ko, Y. A., Qiu, C., Yao, C., Joehanes, R., Grams, M. E., Liang, L., Gluck, C. A., Liu, C., Coresh, J., Hwang, S. J., Levy, D., Boerwinkle, E., Pankow, J. S., Yang, Q., Fornage, M., Fox, C. S., Susztak, K. & 1 others, Köttgen, A., Dec 1 2017, In : Nature communications. 8, 1, 1286.

Research output: Contribution to journalArticle

Open Access
kidney diseases
methylation
kidneys
DNA Methylation
Glomerular Filtration Rate
6 Citations (Scopus)

Experiences of discrimination and incident type 2 diabetes mellitus: The Multi-Ethnic Study of Atherosclerosis (MESA)

Whitaker, K. M., Everson-Rose, S. A., Pankow, J. S., Rodriguez, C. J., Lewis, T. T., Kershaw, K. N., Diez Roux, A. V. & Lutsey, P. L., Jan 1 2017, In : American journal of epidemiology. 186, 4, p. 445-455 11 p.

Research output: Contribution to journalArticle

Open Access
Type 2 Diabetes Mellitus
Atherosclerosis
Confidence Intervals
Waist Circumference
Proportional Hazards Models
11 Citations (Scopus)

Ferritin levels and risk of heart failure—the Atherosclerosis Risk in Communities Study

Silvestre, O. M., Gonçalves, A., Nadruz, W., Claggett, B., Couper, D., Eckfeldt, J. H., Pankow, J., Anker, S. D. & Solomon, S. D., Mar 1 2017, In : European Journal of Heart Failure. 19, 3, p. 340-347 8 p.

Research output: Contribution to journalArticle

Ferritins
Atherosclerosis
Heart Failure
Iron
Confidence Intervals
4 Citations (Scopus)

Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations

Yoneyama, S., Yao, J., Guo, X., Fernandez-Rhodes, L., Lim, U., Boston, J., Buzková, P., Carlson, C. S., Cheng, I., Cochran, B., Cooper, R., Ehret, G., Fornage, M., Gong, J., Gross, M., Gu, C. C., Haessler, J., Haiman, C. A., Henderson, B., Hindorff, L. A. & 30 others, Houston, D., Irvin, M. R., Jackson, R., Kuller, L., Leppert, M., Lewis, C. E., Li, R., Le Marchand, L., Matise, T. C., Nguyen, K. D., Chakravarti, A., Pankow, J. S., Pankratz, N., Pooler, L., Ritchie, M. D., Bien, S. A., Wassel, C. L., Chen, Y. D., Taylor, K. D., Allison, M., Rotter, J. I., Schreiner, P. J., Schumacher, F., Wilkens, L., Boerwinkle, E., Kooperberg, C., Peters, U., Buyske, S., Graff, M. & North, K. E., Feb 1 2017, In : International Journal of Obesity. 41, 2, p. 324-331 8 p.

Research output: Contribution to journalArticle

Open Access
Waist-Hip Ratio
Adiposity
Single Nucleotide Polymorphism
Population
Waist Circumference
12 Citations (Scopus)

Genetics of type 2 diabetes in U.S. Hispanic/Latino individuals: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Qi, Q., Stilp, A. M., Sofer, T., Moon, J. Y., Hidalgo, B., Szpiro, A. A., Wang, T., Ng, M. C. Y., Guo, X., Chen, Y. D. I., Taylor, K. D., Aviles-Santa, M. L., Papanicolaou, G., Pankow, J. S., Schneiderman, N., Laurie, C. C., Rotter, J. I. & Kaplan, R. C., May 1 2017, In : Diabetes. 66, 5, p. 1419-1425 7 p.

Research output: Contribution to journalArticle

Hispanic Americans
Type 2 Diabetes Mellitus
Health
Single Nucleotide Polymorphism
Genome-Wide Association Study
17 Citations (Scopus)

Genetic variants associated with circulating parathyroid hormone

Robinson-Cohen, C., Lutsey, P. L., Kleber, M. E., Nielson, C. M., Mitchell, B. D., Bis, J. C., Eny, K. M., Portas, L., Eriksson, J., Lorentzon, M., Koller, D. L., Milaneschi, Y., Teumer, A., Pilz, S., Nethander, M., Selvin, E., Tang, W., Weng, L. C., Wong, H. S., Lai, D. & 29 others, Peacock, M., Hannemann, A., Völker, U., Homuth, G., Nauk, M., Murgia, F., Pattee, J. W., Orwoll, E., Zmuda, J. M., Riancho, J. A., Wolf, M., Williams, F., Penninx, B., Econs, M. J., Ryan, K. A., Ohlsson, C., Paterson, A. D., Psaty, B. M., Siscovick, D. S., Rotter, J. I., Pirastu, M., Streeten, E., März, W., Fox, C., Coresh, J., Wallaschofski, H., Pankow, J. S., De Boer, I. H. & Kestenbaum, B., May 1 2017, In : Journal of the American Society of Nephrology. 28, 5, p. 1553-1565 13 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Single Nucleotide Polymorphism
Serum
Secondary Hyperparathyroidism
Dihydroxycholecalciferols
8 Citations (Scopus)

Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism

Li, M., Maruthur, N. M., Loomis, S. J., Pietzner, M., North, K. E., Mei, H., Morrison, A. C., Friedrich, N., Pankow, J. S., Nauck, M., Boerwinkle, E., Teumer, A., Selvin, E. & Köttgen, A., Dec 1 2017, In : Scientific reports. 7, 1, 2812.

Research output: Contribution to journalArticle

Open Access
Genetic Loci
Genome-Wide Association Study
Glucose
African Americans
Fasting
1 Citation (Scopus)

Genome-wide association test of multiple continuous traits using imputed SNPs

Wu, B. & Pankow, J., Jan 1 2017, In : Statistics and its Interface. 10, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

Open Access
Genome
Genes
Genotype
Covariates
Medical problems
5 Citations (Scopus)

Genome-wide interaction with selected type 2 diabetes loci reveals novel loci for type 2 diabetes in african americans

Keaton, J. M., Hellwege, J. N., Ng, M. C. Y., Palmer, N. D., Pankow, J. S., Fornage, M., Wilson, J. G., Correa, A., Rasmussen-Torvik, L. J., Rotter, J. I., Chen, Y. D. E. R. I., Taylor, K. D., Rich, S. S., Wagenknecht, L. E., Freedman, B. I. & Bowden, D. W., Jan 1 2017, In : Pacific Symposium on Biocomputing. 0, 212679, p. 242-253 12 p.

Research output: Contribution to journalConference article

African Americans
Type 2 Diabetes Mellitus
Genome
Insulin
Single Nucleotide Polymorphism
3 Citations (Scopus)

Hepatocyte growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease

Bielinski, S. J., Berardi, C., Decker, P. A., Larson, N. B., Bell, E. J., Pankow, J. S., Sale, M. M., Tang, W., Hanson, N. Q., Wassel, C. L., De Andrade, M., Budoff, M. J., Polak, J. F., Sicotte, H. & Tsai, M. Y., Aug 1 2017, In : Heart. 103, 15, p. 1185-1193 9 p.

Research output: Contribution to journalArticle

Open Access
Hepatocyte Growth Factor
Coronary Disease
Biomarkers
Hispanic Americans
African Americans
7 Citations (Scopus)
Brachial Artery
Blood Vessels
Pulse Wave Analysis
Elastic Modulus
Parents

Hospitalization with infection and incident venous thromboembolism: The ARIC study

Cowan, L. T., Lutsey, P. L., Pankow, J. S., Cushman, M. & Folsom, A. R., Mar 1 2017, In : Thrombosis Research. 151, p. 74-78 5 p.

Research output: Contribution to journalArticle

Open Access
Venous Thromboembolism
Atherosclerosis
Hospitalization
Infection
Cross-Over Studies
3 Citations (Scopus)
Protein C
Lipoproteins
Atherosclerosis
Genome
LDL Cholesterol
63 Citations (Scopus)

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

Wheeler, E., Leong, A., Liu, C. T., Hivert, M. F., Strawbridge, R. J., Podmore, C., Li, M., Yao, J., Sim, X., Hong, J., Chu, A. Y., Zhang, W., Wang, X., Chen, P., Maruthur, N. M., Porneala, B. C., Sharp, S. J., Jia, Y., Kabagambe, E. K., Chang, L. C. & 33 others, Chen, W. M., Elks, C. E., Evans, D. S., Fan, Q., Giulianini, F., Go, M. J., Hottenga, J. J., Hu, Y., Jackson, A. U., Kanoni, S., Kim, Y. J., Kleber, M. E., Ladenvall, C., Lecoeur, C., Lim, S. H., Lu, Y., Mahajan, A., Marzi, C., Nalls, M. A., Navarro, P., Nolte, I. M., Rose, L. M., Rybin, D. V., Sanna, S., Shi, Y., Stram, D. O., Takeuchi, F., Pankow, J. S., Heng, C. K., Sabanayagam, C., EPIC-CVD Consortium, EPIC-InterAct Consortium & Lifelines Cohort Study, Sep 1 2017, In : PLoS medicine. 14, 9, e1002383.

Research output: Contribution to journalArticle

Open Access
Type 2 Diabetes Mellitus
Meta-Analysis
Hemoglobins
Glucosephosphate Dehydrogenase Deficiency
Genome
1 Citation (Scopus)

Low high-density lipoprotein cholesterol and particle concentrations are associated with greater levels of endothelial activation markers in Multi-Ethnic Study of Atherosclerosis participants

Steffen, B. T., Bielinski, S. J., Decker, P. A., Berardi, C., Larson, N. B., Pankow, J. S., Michos, E. D., Hanson, N. Q., Herrington, D. M. & Tsai, M. Y., Jul 1 2017, In : Journal of Clinical Lipidology. 11, 4, p. 955-963.e3

Research output: Contribution to journalArticle

HDL Lipoproteins
LDL Cholesterol
HDL Cholesterol
Atherosclerosis
Selectins
10 Citations (Scopus)

Quantifying the extent to which index event biases influence large genetic association studies

Yaghootkar, H., Bancks, M. P., Jones, S. E., McDaid, A., Beaumont, R., Donnelly, L., Wood, A. R., Campbell, A., Tyrrell, J., Hocking, L. J., Tuke, M. A., Ruth, K. S., Pearson, E. R., Murray, A., Freathy, R. M., Munroe, P. B., Hayward, C., Palmer, C., Weedon, M. N., Pankow, J. S. & 2 others, Frayling, T. M. & Kutalik, Z., Mar 1 2017, In : Human molecular genetics. 26, 5, p. 1003-1017 15 p.

Research output: Contribution to journalArticle

Open Access
Genetic Association Studies
Systemic Lupus Erythematosus
RNA
Genome-Wide Association Study
Exons
4 Citations (Scopus)

Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis

Roetker, N. S., Armasu, S. M., Pankow, J. S., Lutsey, P. L., Tang, W., Rosenberg, M. A., Palmer, T. M., Maclehose, R. F., Heckbert, S. R., Cushman, M., de Andrade, M. & Folsom, A. R., Jul 1 2017, In : Journal of Thrombosis and Haemostasis. 15, 7, p. 1334-1343 10 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Venous Thromboembolism
Meta-Analysis
Odds Ratio
Confidence Intervals
3 Citations (Scopus)

Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium

Bien, S. A., Pankow, J. S., Haessler, J., Lu, Y. N., Pankratz, N., Rohde, R. R., Tamuno, A., Carlson, C. S., Schumacher, F. R., Bůžková, P., Daviglus, M. L., Lim, U., Fornage, M., Fernandez-Rhodes, L., Avilés-Santa, L., Buyske, S., Gross, M. D., Graff, M., Isasi, C. R., Kuller, L. H. & 12 others, Manson, J. A. E., Matise, T. C., Prentice, R. L., Wilkens, L. R., Yoneyama, S., Loos, R. J. F., Hindorff, L. A., Le Marchand, L., North, K. E., Haiman, C. A., Peters, U. & Kooperberg, C., Dec 1 2017, In : Diabetologia. 60, 12, p. 2384-2398 15 p.

Research output: Contribution to journalArticle

Open Access
Genomics
Fasting
Epidemiology
Single Nucleotide Polymorphism
Population
34 Citations (Scopus)

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

Rusu, V., Rusu, V., Hoch, E., Mercader, J. M., Gymrek, M., von Grotthuss, M., Fontanillas, P., Spooner, A., Altshuler, D. M., Florez, J. C., Jacobs, S. B. R., Hoch, E., Clish, C. B., Florez, J. C., Jacobs, S. B. R., Mercader, J. M., Florez, J. C., Jacobs, S. B. R., Mercader, J. M., Tenen, D. E. & 51 others, Hartigan, C. R., DeRan, M., Guzman, G., Deik, A. A., Pierce, K. A., Dennis, C., Clish, C. B., Carr, S. A., Wagner, B. K., Schenone, M., Schreiber, S. L., Lander, E. S., Tenen, D. E., Gymrek, M., Ng, M. C. Y., Chen, B. H., Centeno-Cruz, F., Orozco, L., Zerrweck, C., Altshuler, D. M., Altshuler, D. M., Altshuler, D. M., Florez, J. C., Altshuler, D. M., Lander, E. S., Lander, E. S., Ng, M. C. Y., Shriner, D., Chen, B. H., Pankow, J. S., MEDIA Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the MuTHER Consortium, SIGMA T2D Consortium & SIGMA T2D Consortium, Jun 29 2017, In : Cell. 170, 1, p. 199-212.e20

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Haplotypes
CD147 Antigens
Mexico
2016
7 Citations (Scopus)

ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Bell, E. J., Decker, P. A., Pike, M., Wassel, C. L., Tsai, M. Y., Pankow, J., Tang, W., Hanson, N. Q., Alexander, K., Zakai, N. A., Cushman, M. & Bielinski, S. J., Aug 1 2016, In : Atherosclerosis. 251, p. 422-429 8 p.

Research output: Contribution to journalArticle

Selectins
Blood Group Antigens
Atherosclerosis
Alleles
von Willebrand Factor
36 Citations (Scopus)

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancáková, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., Van Der Lee, S. J. & 118 others, Gillson, C., Al Olama, A. A., Amouyel, P., Arriola, L., Arveiler, D., Aviles-Olmos, I., Balkau, B., Barricarte, A., Barroso, I., Garcia, S. B., Bis, J. C., Blankenberg, S., Boehnke, M., Boeing, H., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bowden, S., Caldas, C., Caslake, M., Cupples, L. A., Cruchaga, C., Czajkowski, J., Den Hoed, M., Dunn, J. A., Earl, H. M., Ehret, G. B., Ferrannini, E., Ferrieres, J., Foltynie, T., Ford, I., Forouhi, N. G., Gianfagna, F., Gonzalez, C., Grioni, S., Hiller, L., Jansson, J. H., Jørgensen, M. E., Jukema, J. W., Kaaks, R., Kee, F., Kerrison, N. D., Key, T. J., Kontto, J., Kote-Jarai, Z., Kraja, A. T., Kuulasmaa, K., Kuusisto, J., Linneberg, A., Liu, C., Marenne, G., Mohlke, K. L., Morris, A. P., Muir, K., Müller-Nurasyid, M., Munroe, P. B., Navarro, C., Nielsen, S. F., Nilsson, P. M., Nordestgaard, B. G., Packard, C. J., Palli, D., Panico, S., Peloso, G. M., Perola, M., Peters, A., Poole, C. J., Quirós, J. R., Rolandsson, O., Sacerdote, C., Salomaa, V., Sánchez, M. J., Sattar, N., Sharp, S. J., Sims, R., Slimani, N., Smith, J. A., Thompson, D. J., Trompet, S., Tumino, R., Van Der A, D. L., Van Der Schouw, Y. T., Virtamo, J., Walker, M., Walter, K., Abraham, J. E., Amundadottir, L. T., Butterworth, A. S., Aponte, J. L., Dupuis, J., Easton, D. F., Eeles, R. A., Erdmann, J., Franks, P. W., Frayling, T. M., Hansen, T., Howson, J. M. M., Jørgensen, T., Kooner, J., Laakso, M., McCarthy, M. I., Pankow, J. S., Pedersen, O., Riboli, E., Rotter, J. I., Saleheen, D., Samani, N. J., Schunkert, H., Vollenweider, P., O'Rahilly, S., Deloukas, P., Danesh, J., Goodarzi, M. O., Kathiresan, S., Meigs, J. B., Ehm, M. G., Wareham, N. J. & Waterworth, D. M., Jun 1 2016, In : Science Translational Medicine. 8, 341, 341ra76.

Research output: Contribution to journalArticle

Coronary Disease
Type 2 Diabetes Mellitus
Glucose
Pharmaceutical Preparations
Genes
23 Citations (Scopus)

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Ried, J. S., Jeff, J. M., Chu, A. Y., Bragg-Gresham, J. L., Van Dongen, J., Huffman, J. E., Ahluwalia, T. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Standáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., Van Der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. D. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D'avila, F., De Geus, E. J. C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A. E., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. P., Glorioso, N., Graff, M., Grallert, H., Grarup, N., Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J. J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Marie Justesen, J., Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-Kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, A., Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., Mcardle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-Madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., Van Der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M. C., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-Armstrong, L. M., Zhao, J. H., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, T., Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M. R., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, O., Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, P. E. H., Shudiner, A. R., Smit, J. H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., Van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., Mccarthy, M. I., North, K. E., O'connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., Nov 23 2016, In : Nature communications. 7, 13357.

Research output: Contribution to journalArticle

loci
Principal Component Analysis
phenotype
Meta-Analysis
Phenotype
29 Citations (Scopus)

Association of 1,5-anhydroglucitol with cardiovascular disease and mortality

Selvin, E., Rawlings, A., Lutsey, P., Maruthur, N., Pankow, J. S., Steffes, M. & Coresh, J., Jan 1 2016, In : Diabetes. 65, 1, p. 201-208 8 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Mortality
Atherosclerosis
Type 1 Diabetes Mellitus
Proportional Hazards Models
6 Citations (Scopus)

Association of lipid-related genetic variants with the incidence of atrial fibrillation: The AFGen consortium

Norby, F. L., Eryd, S. A., Niemeijer, M. N., Rose, L. M., Smith, A. V., Yin, X., Agarwal, S. K., Arking, D. E., Chasman, D. L., Chen, L. Y., Eijgelsheim, M., Engström, G., Franco, O. H., Heeringa, J., Hindy, G., Hofman, A., Lutsey, P. L., Magnani, J. W., McManus, D. D., Orho-Melander, M. & 10 others, Pankow, J. S., Rukh, G., Schulz, C. A., Uitterlinden, A. G., Albert, C. M., Benjamin, E. J., Gudnason, V., Smith, J. G., Stricker, B. H. C. & Alonso, A., Mar 1 2016, In : PloS one. 11, 3, e0151932.

Research output: Contribution to journalArticle

Atrial Fibrillation
Genes
Lipids
incidence
Incidence
2 Citations (Scopus)

Association of the IGF1 gene with fasting insulin levels

Willems, S. M., Cornes, B. K., Brody, J. A., Morrison, A. C., Lipovich, L., Dauriz, M., Chen, Y., Liu, C. T., Rybin, D. V., Gibbs, R. A., Muzny, D., Pankow, J. S., Psaty, B. M., Boerwinkle, E., Rotter, J. I., Siscovick, D. S., Vasan, R. S., Kaplan, R. C., Isaacs, A., Dupuis, J. & 2 others, van Duijn, C. M. & Meigs, J. B., Aug 1 2016, In : European Journal of Human Genetics. 24, 9, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

Fasting
Insulin
Insulin-Like Growth Factor I
Genome-Wide Association Study
Genes

Blood group antigen loci demonstrate multivariate genetic associations with circulating cellular adhesion protein levels in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Decker, P. A., Wassel, C. L., Pankow, J., Tang, W., Hanson, N. Q., Tsai, M. Y. & Bielinski, S. J., Apr 1 2016, In : Human Genetics. 135, 4, p. 415-423 9 p.

Research output: Contribution to journalArticle

Blood Group Antigens
Atherosclerosis
Proteins
Quantitative Trait Loci
Genome
6 Citations (Scopus)

Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case–cohort analysis of the ARIC Study

Luft, V. C., Duncan, B. B., Schmidt, M. I., Chambless, L. E., Pankow, J., Hoogeveen, R. C., Couper, D. J. & Heiss, G., Oct 1 2016, In : Diabetic Medicine. 33, 10, p. 1392-1398 7 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Fasting
Glucose
Confidence Intervals
Waist-Hip Ratio
9 Citations (Scopus)

Circulating cellular adhesion molecules and risk of diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)

Pankow, J., Decker, P. A., Berardi, C., Hanson, N. Q., Sale, M., Tang, W., Kanaya, A. M., Larson, N. B., Tsai, M. Y., Wassel, C. L. & Bielinski, S. J., Jul 1 2016, In : Diabetic Medicine. 33, 7, p. 985-991 7 p.

Research output: Contribution to journalArticle

E-Selectin
Intercellular Adhesion Molecule-1
Atherosclerosis
Vascular Cell Adhesion Molecule-1
Cadherins
10 Citations (Scopus)

Circulating level of hepatocyte growth factor predicts incidence of type 2 diabetes mellitus: The Multi-Ethnic Study of Atherosclerosis (MESA)

Bancks, M. P., Bielinski, S. J., Decker, P. A., Hanson, N. Q., Larson, N. B., Sicotte, H., Wassel, C. L. & Pankow, J., Mar 1 2016, In : Metabolism: clinical and experimental. 65, 3, p. 64-72 9 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Type 2 Diabetes Mellitus
Atherosclerosis
Incidence
Social Adjustment
190 Citations (Scopus)

DNA methylation-based measures of biological age: Meta-analysis predicting time to death

Chen, B. H., Marioni, R. E., Colicino, E., Peters, M. J., Ward-Caviness, C. K., Tsai, P. C., Roetker, N. S., Just, A. C., Demerath, E. W., Guan, W., Bressler, J., Fornage, M., Studenski, S., Vandiver, A. R., Moore, A. Z., Tanaka, T., Kiel, D. P., Liang, L., Vokonas, P., Schwartz, J. & 46 others, Lunetta, K. L., Murabito, J. M., Bandinelli, S., Hernandez, D. G., Melzer, D., Nalls, M., Pilling, L. C., Price, T. R., Singleton, A. B., Gieger, C., Holle, R., Kretschmer, A., Kronenberg, F., Kunze, S., Linseisen, J., Meisinger, C., Rathmann, W., Waldenberger, M., Visscher, P. M., Shah, S., Wray, N. R., McRae, A. F., Franco, O. H., Hofman, A., Uitterlinden, A. G., Absher, D., Assimes, T., Levine, M. E., Lu, A. T., Tsao, P. S., Hou, L., Manson, J. A. E., Carty, C. L., LaCroix, A. Z., Reiner, A. P., Spector, T. D., Feinberg, A. P., Levy, D., Baccarelli, A., Meurs, J. V., Bell, J. T., Peters, A., Deary, I. J., Pankow, J. S., Ferrucci, L. & Horvath, S., Jan 1 2016, In : Aging. 8, 9, p. 1844-1865 22 p.

Research output: Contribution to journalArticle

DNA Methylation
Epigenomics
Meta-Analysis
Mortality
Ethnic Groups
63 Citations (Scopus)

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, S., Marzi, C., Aslibekyan, S., Mendelson, M. M., Conneely, K. N., Tanaka, T., Colicino, E., Waite, L. L., Joehanes, R., Guan, W., Brody, J. A., Elks, C., Marioni, R., Jhun, M. A., Agha, G., Bressler, J., Ward-Caviness, C. K., Chen, B. H., Huan, T., Bakulski, K. & 67 others, Salfati, E. L., Fiorito, G., Wahl, S., Schramm, K., Sha, J., Hernandez, D. G., Just, A. C., Smith, J. A., Sotoodehnia, N., Pilling, L. C., Pankow, J. S., Tsao, P. S., Liu, C., Zhao, W., Guarrera, S., Michopoulos, V. J., Smith, A. K., Peters, M. J., Melzer, D., Vokonas, P., Fornage, M., Prokisch, H., Bis, J. C., Chu, A. Y., Herder, C., Grallert, H., Yao, C., Shah, S., McRae, A. F., Lin, H., Horvath, S., Fallin, D., Hofman, A., Wareham, N. J., Wiggins, K. L., Feinberg, A. P., Starr, J. M., Visscher, P. M., Murabito, J. M., Kardia, S. L. R., Absher, D. M., Binder, E. B., Singleton, A. B., Bandinelli, S., Peters, A., Waldenberger, M., Matullo, G., Schwartz, J. D., Demerath, E. W., Uitterlinden, A. G., Meurs, J. B. J., Franco, O. H., Chen, Y. D. I., Levy, D., Turner, S. T., Deary, I. J., Ressler, K. J., Dupuis, J., Ferrucci, L., Ong, K. K., Assimes, T. L., Boerwinkle, E., Koenig, W., Arnett, D. K., Baccarelli, A. A., Benjamin, E. J. & Dehghan, A., Dec 12 2016, In : Genome biology. 17, 1, 255.

Research output: Contribution to journalArticle

methylation
DNA methylation
DNA Methylation
inflammation
Inflammation
160 Citations (Scopus)

Epigenetic Signatures of Cigarette Smoking

Joehanes, R., Just, A. C., Marioni, R. E., Pilling, L. C., Reynolds, L. M., Mandaviya, P. R., Guan, W., Xu, T., Elks, C. E., Aslibekyan, S., Moreno-Macias, H., Smith, J. A., Brody, J. A., Dhingra, R., Yousefi, P., Pankow, J. S., Kunze, S., Shah, S. H., McRae, A. F., Lohman, K. & 63 others, Sha, J., Absher, D. M., Ferrucci, L., Zhao, W., Demerath, E. W., Bressler, J., Grove, M. L., Huan, T., Liu, C., Mendelson, M. M., Yao, C., Kiel, D. P., Peters, A., Wang-Sattler, R., Visscher, P. M., Wray, N. R., Starr, J. M., Ding, J., Rodriguez, C. J., Wareham, N. J., Irvin, M. R., Zhi, D., Barrdahl, M., Vineis, P., Ambatipudi, S., Uitterlinden, A. G., Hofman, A., Schwartz, J., Colicino, E., Hou, L., Vokonas, P. S., Hernandez, D. G., Singleton, A. B., Bandinelli, S., Turner, S. T., Ware, E. B., Smith, A. K., Klengel, T., Binder, E. B., Psaty, B. M., Taylor, K. D., Gharib, S. A., Swenson, B. R., Liang, L., Demeo, D. L., O'Connor, G. T., Herceg, Z., Ressler, K. J., Conneely, K. N., Sotoodehnia, N., Kardia, S. L. R., Melzer, D., Baccarelli, A. A., Van Meurs, J. B. J., Romieu, I., Arnett, D. K., Ong, K. K., Liu, Y., Waldenberger, M., Deary, I. J., Fornage, M., Levy, D. & London, S. J., Oct 1 2016, In : Circulation: Cardiovascular Genetics. 9, 5, p. 436-447 12 p.

Research output: Contribution to journalArticle

Epigenomics
Smoking
DNA Methylation
Methylation
Tobacco
5 Citations (Scopus)

Erratum: Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (American Society for Clinical Investigation (2015)125:4 (1739-1751) DOI 10.1172/JCI74692)

Knowles, J. W., Xie, W., Zhang, Z., Chennamsetty, I., Assimes, T. L., Paananen, J., Hansson, O., Pankow, J., Goodarzi, M. O., Carcamo-Orive, I., Morris, A. P., Chen, Y. D. I., Mäkinen, V. P., Ganna, A., Mahajan, A., Guo, X., Abbasi, F., Greenawalt, D. M., Lum, P., Molony, C. & 19 others, Lind, L., Lindgren, C., Raffel, L. J., Tsao, P. S., Schadt, E. E., Rotter, J. I., Sinaiko, A., Reaven, G., Yang, X., Hsiung, C. A., Groop, L., Cordell, H. J., Laakso, M., Hao, K., Ingelsson, E., Frayling, T. M., Weedon, M. N., Walker, M. & Quertermous, T., Jan 4 2016, In : Journal of Clinical Investigation. 126, 1, 1 p.

Research output: Contribution to journalComment/debate

Acetyltransferases
Insulin Resistance
Genes
7 Citations (Scopus)

Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies

Allen, N. B., Lloyd-Jones, D., Hwang, S. J., Rasmussen-Torvik, L., Fornage, M., Morrison, A. C., Baldridge, A. S., Boerwinkle, E., Levy, D., Cupples, L. A., Fox, C. S., Thanassoulis, G., Dufresne, L., Daviglus, M., Johnson, A. D., Reis, J., Rotter, J., Palmas, W., Allison, M., Pankow, J. S. & 1 others, O'Donnell, C. J., May 1 2016, In : American Heart Journal. 175, p. 112-120 9 p.

Research output: Contribution to journalArticle

Genetic Loci
Genome-Wide Association Study
Meta-Analysis
Health
Single Nucleotide Polymorphism
3 Citations (Scopus)

Genome-wide interaction with insulin secretion loci reveals novel loci for type 2 diabetes in African Americans

Keaton, J. M., Hellwege, J. N., Ng, M. C. Y., Palmer, N. D., Pankow, J. S., Fornage, M., Wilson, J. G., Correa, A., Rasmussen-Torvik, L. J., Rotter, J. I., Chen, Y. D. I., Taylor, K. D., Rich, S. S., Wagenknecht, L. E., Freedman, B. I. & Bowden, D. W., Jul 1 2016, In : PloS one. 11, 7, e0159977.

Research output: Contribution to journalArticle

insulin secretion
African Americans
Medical problems
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
4 Citations (Scopus)

Hepatocyte growth factor is positively associated with risk of stroke: The MESA (Multi-Ethnic Study of Atherosclerosis)

Bell, E. J., Larson, N. B., Decker, P. A., Pankow, J., Tsai, M. Y., Hanson, N. Q., Wassel, C. L., Longstreth, W. T. & Bielinski, S. J., Nov 1 2016, In : Stroke. 47, 11, p. 2689-2694 6 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Atherosclerosis
Stroke
Confidence Intervals
Confounding Factors (Epidemiology)
9 Citations (Scopus)

Hospitalized Infection as a Trigger for Acute Ischemic Stroke: The Atherosclerosis Risk in Communities Study

Cowan, L. T., Alonso, A., Pankow, J. S., Folsom, A. R., Rosamond, W. D., Gottesman, R. F. & Lakshminarayan, K., Jun 1 2016, In : Stroke. 47, 6, p. 1612-1617 6 p.

Research output: Contribution to journalArticle

Atherosclerosis
Stroke
Infection
Cardiovascular Diseases
Odds Ratio
6 Citations (Scopus)

Impact of adiposity on cellular adhesion: The Multi-Ethnic Study of atherosclerosis (MESA)

Christoph, M. J., Allison, M. A., Pankow, J. S., Decker, P. A., Kirsch, P. S., Tsai, M. Y., Sale, M. M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Berardi, C., Wassel, C. L., Larson, N. B. & Bielinski, S. J., Jan 1 2016, In : Obesity. 24, 1, p. 223-230 8 p.

Research output: Contribution to journalArticle

Adiposity
Atherosclerosis
Intra-Abdominal Fat
Waist-Hip Ratio
Selectins
2 Citations (Scopus)

Imputation of missing covariate values in epigenome-wide analysis of DNA methylation data

Wu, C., Demerath, E. W., Pankow, J. S., Bressler, J., Fornage, M., Grove, M. L., Chen, W. & Guan, W., Feb 1 2016, In : Epigenetics. 11, 2, p. 132-139 8 p.

Research output: Contribution to journalArticle

DNA Methylation
Methylation
Smoking
Environmental Exposure
Leukocyte Count
13 Citations (Scopus)

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S. J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L. P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., Van Setten, J., Smith, A. V. & 80 others, Vojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y. D. I., Cupples, L. A., De Jong, P. A., De Koning, H., De Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Launer, L. J., Massaro, J., Mehran, R., Mitchell, B. D., Mosley, T. H., De Mutsert, R., Newman, A. B., Nguyen, K. D., North, K. E., O'Connell, J. R., Oudkerk, M., Pankow, J. S., Peloso, G. M., Post, W., Province, M. A., Raffield, L. M., Raitakari, O. T., Reilly, D. F., Rivadeneira, F., Rosendaal, F., Sartori, S., Taylor, K. D., Teumer, A., Trompet, S., Turner, S. T., Uitterlinden, A. G., Vaidya, D., Van Der Lugt, A., Völker, U., Wardlaw, J. M., Wassel, C. L., Weiss, S., Wojczynski, M. K., Becker, D. M., Becker, L. C., Boerwinkle, E., Bowden, D. W., Deary, I. J., Dehghan, A., Felix, S. B., Gudnason, V., Lehtimäki, T., Mathias, R., Mook-Kanamori, D. O., Psaty, B. M., Rader, D. J., Rotter, J. I., Wilson, J. G., Van Duijn, C. M., Völzke, H., Kathiresan, S., Peyser, P. A. & O'Donnell, C. J., Dec 1 2016, In : Circulation: Cardiovascular Genetics. 9, 6, p. 511-520 10 p.

Research output: Contribution to journalArticle

Exome
Atherosclerosis
Coronary Vessels
Carotid Intima-Media Thickness
Coronary Disease
44 Citations (Scopus)

Obstructive sleep apnea and incident type 2 diabetes

Nagayoshi, M., Punjabi, N. M., Selvin, E., Pankow, J. S., Shahar, E., Iso, H., Folsom, A. R. & Lutsey, P. L., Sep 1 2016, In : Sleep Medicine. 25, p. 156-161 6 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Type 2 Diabetes Mellitus
Polysomnography
Adiposity
Waist Circumference
10 Citations (Scopus)
Exome
Fasting
Atherosclerosis
Software
Genome
5 Citations (Scopus)

On Sample Size and Power Calculation for Variant Set-Based Association Tests

Wu, B. & Pankow, J., Mar 1 2016, In : Annals of Human Genetics. 80, 2, p. 136-143 8 p.

Research output: Contribution to journalArticle

Sample Size
Exome
Genome
6 Citations (Scopus)

Parathyroid hormone and the risk of incident hypertension: The Atherosclerosis Risk in Communities study

Yao, L., Folsom, A. R., Pankow, J. S., Selvin, E., Michos, E. D., Alonso, A., Tang, W. & Lutsey, P. L., Feb 1 2016, In : Journal of hypertension. 34, 2, p. 196-203 8 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Atherosclerosis
Hypertension
Demography
Chymosin
2 Citations (Scopus)

Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study

Reis, J. P., Selvin, E., Pankow, J. S., Michos, E. D., Rebholz, C. M. & Lutsey, P. L., Jun 1 2016, In : Diabetes and Metabolism. 42, 3, p. 162-169 8 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Atherosclerosis
hydroquinone
Insulin Resistance
Life Style
5 Citations (Scopus)

Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study

Florido, R., Zhao, D., Ndumele, C. E., Lutsey, P. L., Mcevoy, J. W., Windham, B. G., Pankow, J., Guallar, E. & Michos, E. D., Sep 1 2016, In : Journal of the American Heart Association. 5, 9, e003505.

Research output: Contribution to journalArticle

Coronary Disease
Atherosclerosis
Cardiovascular Diseases
Exercise
Proportional Hazards Models
17 Citations (Scopus)

Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study

Loehr, L. R., Meyer, M. L., Poon, A. K., Selvin, E., Palta, P., Tanaka, H., Pankow, J. S., Wright, J. D., Griswold, M. E., Wagenknecht, L. E. & Heiss, G., Sep 1 2016, In : American journal of hypertension. 29, 9, p. 1038-1045 8 p.

Research output: Contribution to journalArticle

Prediabetic State
Vascular Stiffness
Atherosclerosis
Glucose
Thigh
2 Citations (Scopus)

Prospective study of γ′ fibrinogen and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)

Folsom, A. R., Tang, W., George, K. M., Heckbert, S. R., MacLehose, R. F., Cushman, M. & Pankow, J. S., Mar 1 2016, In : Thrombosis Research. 139, p. 44-49 6 p.

Research output: Contribution to journalArticle

Thromboembolism
Venous Thromboembolism
Fibrinogen
Prospective Studies
African Americans
1 Citation (Scopus)

Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project

Kan, M., Auer, P. L., Wang, G. T., Bucasas, K. L., Hooker, S., Rodriguez, A., Li, B., Ellis, J., Adrienne Cupples, L., Ida Chen, Y. D., Dupuis, J., Fox, C. S., Gross, M. D., Smith, J. D., Heard-Costa, N., Meigs, J. B., Pankow, J. S., Rotter, J. I., Siscovick, D., Wilson, J. G. & 17 others, Shendure, J., Jackson, R., Peters, U., Zhong, H., Lin, D., Hsu, L., Franceschini, N., Carlson, C., Abecasis, G., Gabriel, S., Bamshad, M. J., Altshuler, D., Nickerson, D. A., North, K. E., Lange, L. A., Reiner, A. P. & Leal, S. M., Aug 1 2016, In : European Journal of Human Genetics. 24, 8, p. 1181-1187 7 p.

Research output: Contribution to journalArticle

Exome
National Heart, Lung, and Blood Institute (U.S.)
Waist-Hip Ratio
African Americans
I-kappa B Kinase