Find Research Outputs

Search concepts
Selected Filters
2019

3,3’-Diindolylmethane inhibits patient-derived xenograft colon tumor growth by targeting COX1/2 and ERK1/2

Tian, X., Liu, K. D., Zu, X., Ma, F., Li, Z., Lee, M. H., Chen, H., Li, Y., Zhao, Y., Liu, F., Oi, N., Bode, A. M., Dong, Z. & Kim, D. J., Apr 28 2019, In : Cancer Letters. 448, p. 20-30 11 p.

Research output: Contribution to journalArticle

Heterografts
Colon
Growth
Neoplasms
Colonic Neoplasms
2 Citations (Scopus)

AKt as a therapeutic target for cancer

Song, M., Bode, A. M., Dong, Z. & Lee, M. H., Jan 1 2019, In : Cancer Research. 79, 6, p. 1019-1031 13 p.

Research output: Contribution to journalReview article

Phosphatidylinositol 3-Kinases
Neoplasms
Phosphotransferases
Glycogen Synthase Kinases
Thymoma
Peptides
Membranes
Pharmaceutical Preparations
Amino Acids
Intracellular Membranes

Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma

Zhao, Z., Jin, G., Yao, K., Liu, K., Liu, F., Chen, H., Wang, K., Gorja, D. R., Kanamata Reddy, S. R., Bode, A. M., Guo, Z. & Dong, Z., Jun 1 2019, In : Molecular Carcinogenesis. 58, 6, p. 1056-1067 12 p.

Research output: Contribution to journalArticle

Aurora Kinase B
Osteosarcoma
Growth
Heterografts
Tissue Array Analysis

Cell growth inhibition by 3-deoxysappanchalcone is mediated by directly targeting the TOPK signaling pathway in colon cancer

Zhao, R., Huang, H., Choi, B. Y., Liu, X., Zhang, M., Zhou, S., Song, M., Yin, F., Chen, H., Shim, J. H., Bode, A. M., Dong, Z. & Lee, M. H., Aug 1 2019, In : Phytomedicine. 61, 152813.

Research output: Contribution to journalArticle

Colonic Neoplasms
Growth
Phosphotransferases
Caesalpinia
Cell Proliferation
1 Citation (Scopus)

Ethyl gallate as a novel ERK1/2 inhibitor suppresses patient-derived esophageal tumor growth

Liu, F., Zu, X., Xie, X., Liu, K., Chen, H., Wang, T., Liu, F., Bode, A. M., Zheng, Y., Dong, Z. & Kim, D. J., Apr 1 2019, In : Molecular Carcinogenesis. 58, 4, p. 533-543 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Growth
Neoplasms
Cyclin A2
Euphorbia

Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo

Xie, X., Liu, K., Liu, F., Chen, H., Wang, X., Zu, X., Ma, X., Wang, T., Wu, Q., Zheng, Y., Bode, A. M., Dong, Z. & Kim, D. J., Feb 1 2019, In : Cancer Letters. 442, p. 126-136 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Growth
MAP Kinase Kinase 3
gossypetin
In Vitro Techniques
1 Citation (Scopus)

Gossypin inhibits gastric cancer growth by direct targeting of AURKA and RSK2

Wang, L., Wang, X., Chen, H., Zu, X., Ma, F., Liu, K., Bode, A. M., Dong, Z. & Kim, D. J., Mar 1 2019, In : Phytotherapy Research. 33, 3, p. 640-650 11 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Stomach Neoplasms
Growth
flavone
Cyclin A2

Inhibition of LTA4H by bestatin in human and mouse colorectal cancer

Zhao, S., Yao, K., Li, D., Liu, K., Jin, G., Yan, M., Wu, Q., Chen, H., Shin, S. H., Bai, R., Wang, G., Bode, A. M., Dong, Z., Guo, Z. & Dong, Z., Jun 1 2019, In : EBioMedicine. 44, p. 361-374 14 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Leukotriene B4
Biomarkers
Leukotriene B4 Receptors
leukotriene A4 hydrolase

Lapachol is a novel ribosomal protein S6 kinase 2 inhibitor that suppresses growth and induces intrinsic apoptosis in esophageal squamous cell carcinoma cells

Zu, X., Xie, X., Zhang, Y., Liu, K., Bode, A. M., Dong, Z. & Kim, D. J., Sep 1 2019, In : Phytotherapy Research. 33, 9, p. 2337-2346 10 p.

Research output: Contribution to journalArticle

lapachol
Growth Inhibitors
Apoptosis
Bignoniaceae
Growth

Lin28a expression protects against streptozotocin-induced β-cell destruction and prevents diabetes in mice

Sung, Y., Jeong, J., Kang, R. J., Choi, M., Park, S., Kwon, W., Lee, J., Jang, S., Park, S. J., Kim, S. H., Yi, J., Choi, S. K., Lee, M. H., Liu, K., Dong, Z., Ryoo, Z. Y. & Kim, M. O., Apr 1 2019, In : Cell Biochemistry and Function. 37, 3, p. 139-147 9 p.

Research output: Contribution to journalArticle

Cell growth
Streptozocin
Medical problems
Genes
Cells

Purpurogallin is a novel mitogen-activated protein kinase kinase 1/2 inhibitor that suppresses esophageal squamous cell carcinoma growth in vitro and in vivo

Xie, X., Zu, X., Liu, F., Wang, T., Wang, X., Chen, H., Liu, K., Wang, P., Liu, F., Zheng, Y., Bode, A. M., Dong, Z. & Kim, D. J., Jan 1 2019, In : Molecular Carcinogenesis. 58, 7, p. 1248-1259 12 p.

Research output: Contribution to journalArticle

MAP Kinase Kinase 2
MAP Kinase Kinase 1
Growth
Cyclin A2
G2 Phase Cell Cycle Checkpoints

Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo

Liu, X., Song, M., Wang, P., Zhao, R., Chen, H., Zhang, M., Shi, Y., Liu, K., Liu, F., Yang, R., Li, E., Bode, A. M., Dong, Z. & Lee, M. H., Aug 15 2019, In : International Journal of Cancer. 145, 4, p. 1007-1019 13 p.

Research output: Contribution to journalArticle

Open Access
Phosphotransferases
Growth
Heterografts
Therapeutics
Tumor Burden
2018
3 Citations (Scopus)

Carnosol suppresses patient-derived gastric tumor growth by targeting RSK2

Wang, L., Zhang, Y., Liu, K., Chen, H., Yang, R., Ma, X., Kim, H. G., Bode, A. M., Kim, D. J. & Dong, Z., Sep 1 2018, In : Oncotarget. 9, 76, p. 34200-34212 13 p.

Research output: Contribution to journalArticle

Stomach
Growth
Stomach Neoplasms
Neoplasms
Origanum

Dinitrosopiperazine-decreased PKP3 through upregulating miR-149 participates in nasopharyngeal carcinoma metastasis

Li, Y., Ju, K., Wang, W., Liu, Z., Xie, H., Jiang, Y., Jiang, G., Lu, J., Dong, Z. & Tang, F., Dec 1 2018, In : Molecular Carcinogenesis. 57, 12, p. 1763-1779 17 p.

Research output: Contribution to journalArticle

Open Access
Neoplasm Metastasis
Nasopharyngeal carcinoma
Carcinogens
Therapeutics
3 Citations (Scopus)

FGFR2 regulation by picrasidine Q inhibits the cell growth and induces apoptosis in esophageal squamous cell carcinoma

Shi, Y., Liu, X., Fredimoses, M., Song, M., Chen, H., Liu, K., Lee, M. H. & Dong, Z., Feb 1 2018, In : Journal of Cellular Biochemistry. 119, 2, p. 2231-2239 9 p.

Research output: Contribution to journalArticle

Cell growth
Receptor, Fibroblast Growth Factor, Type 2
Cells
Apoptosis
Cell Proliferation

Jazf1 promotes prostate cancer progression by activating JNK/ Slug

Sung, Y., Park, S., Park, S. J., Jeong, J., Choi, M., Lee, J., Kwon, W., Jang, S., Lee, M. H., Kim, D. J., Liu, K., Kim, S. H., Lee, J. H., Ha, Y. S., Kwon, T. G., Lee, S., Dong, Z., Ryoo, Z. Y. & Kim, M. O., Jan 1 2018, In : Oncotarget. 9, 1, p. 755-765 11 p.

Research output: Contribution to journalArticle

Gastropoda
Zinc Fingers
Prostatic Neoplasms
Proteins
Nuclear Receptor Subfamily 2, Group C, Member 2
5 Citations (Scopus)

Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization

Yeung, Y. T., Yin, S., Lu, B., Fan, S., Yang, R., Bai, R., Zhang, C., Bode, A. M., Liu, K. & Dong, Z., Feb 1 2018, In : EBioMedicine. 28, p. 51-61 11 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cells
Epidermal Growth Factor Receptor
p38 Mitogen-Activated Protein Kinases
Tetraploidy

MICAl2 mediates p53 ubiquitin degradation through oxidating p53 methionine 40 and 160 and promotes colorectal cancer malignance

Lu, J., Li, Y., Wu, Y., Zhou, S., Duan, C., Dong, Z., Kang, T. & Tang, F., Jan 1 2018, In : Theranostics. 8, 19, p. 5289-5306 18 p.

Research output: Contribution to journalArticle

Open Access
Ubiquitin
Methionine
Colorectal Neoplasms
Growth
Carcinogenesis
1 Citation (Scopus)

MNAT1 is overexpressed in colorectal cancer and mediates p53 ubiquitin-degradation to promote colorectal cancer malignance

Zhou, S., Lu, J., Li, Y., Chen, C., Cai, Y., Tan, G., Peng, Z., Zhang, Z., Dong, Z., Kang, T. & Tang, F., Nov 26 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 284.

Research output: Contribution to journalArticle

Open Access
Ubiquitin
Colorectal Neoplasms
Nude Mice
Growth
Western Blotting
3 Citations (Scopus)

Pharmacological TLR4 antagonism using topical resatorvid blocks solar UV-induced skin tumorigenesis in SKH-1 mice

Blohm-Mangone, K., Burkett, N. B., Tahsin, S., Myrdal, P. B., Aodah, A., Ho, B., Janda, J., McComas, M., Saboda, K., Roe, D. J., Dong, Z., Bode, A. M., Petricoin, E. F., Calvert, V. S., Curiel-Lewandrowski, C., Alberts, D. S., Wondrak, G. T. & Dickinson, S. E., May 1 2018, In : Cancer Prevention Research. 11, 5, p. 265-277 13 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Carcinogenesis
Pharmacology
Skin
Skin Neoplasms
1 Citation (Scopus)

PKCι is a target of 7,8,4′-trihydroxyisoflavone for the suppression of UVB-induced MMP-1 expression

Lim, T. G., Kim, Y. A., Kim, J. E., Baek, S., Lee, S. Y., Lee, C. C., Chen, H., Kim, J. R., Kwon, J. Y., Bode, A. M., Lee, C. Y., Dong, Z., Oh, D. K., Park, J. S. & Lee, K. W., May 1 2018, In : Experimental Dermatology. 27, 5, p. 449-452 4 p.

Research output: Contribution to journalLetter

Matrix Metalloproteinase 1
Assays
Bioconversion
Skin
Fluorescence Polarization
3 Citations (Scopus)

RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation

Yao, K., Lee, S. Y., Peng, C., Lim, D. Y., Yamamoto, H., Ryu, J., Lim, T. G., Chen, H., Jin, G., Zhao, Z., Han, Y., Ma, W. Y., Bode, A. M. & Dong, Z., Jun 1 2018, In : Oncogene. 37, 26, p. 3501-3513 13 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Colon
Phosphorylation
Inflammation
Ubiquitination
6 Citations (Scopus)

Targeting AKT with oridonin inhibits growth of esophageal squamous cell carcinoma in vitro and patient-derived xenografts in vivo

Song, M., Liu, X., Liu, K., Zhao, R., Huang, H., Shi, Y., Zhang, M., Zhou, S., Xie, H., Chen, H., Li, Y., Zheng, Y., Wu, Q., Liu, F., Li, E., Bode, A. M., Dong, Z. & Lee, M. H., Jul 1 2018, In : Molecular Cancer Therapeutics. 17, 7, p. 1540-1553 14 p.

Research output: Contribution to journalArticle

Heterografts
Growth
Isodon
Caspase 7
Neoplasms
2 Citations (Scopus)

Targeting PRPK and TOPK for skin cancer prevention and therapy

Roh, E., Lee, M. H., Zykova, T. A., Zhu, F., Nadas, J., Kim, H. G., Bae, K. B., Li, Y., Cho, Y. Y., Curiel-Lewandrowski, C., Einspahr, J., Dickinson, S. E., Bode, A. M. & Dong, Z., Oct 18 2018, In : Oncogene. 37, 42, p. 5633-5647 15 p.

Research output: Contribution to journalArticle

Lymphokine-Activated Killer Cells
Skin Neoplasms
Protein Kinases
Skin
Hairless Mouse
2 Citations (Scopus)

Targeting prpk function blocks colon cancer metastasis

Zykova, T., Zhu, F., Wang, L., Li, H., Lim, D. Y., Yao, K., Roh, E., Yoon, S. P., Kim, H. G., Bae, K. B., Wen, W., Shin, S. H., Nadas, J., Li, Y., Ma, W., Bode, A. M. & Dong, Z., May 1 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 1101-1113 13 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Protein Kinases
Neoplasm Metastasis
Fusidic Acid
Fluorouracil

The Ashitaba (Angelica keiskei) Chalcones 4-hydroxyderricin and xanthoangelol suppress melanomagenesis by targeting BRAF and PI3K

Zhang, T., Wang, Q., Fredimoses, M., Gao, G., Wang, K., Chen, H., Wang, T., Oi, N., Zykova, T. A., Reddy, K., Yao, K., Ma, W., Chang, X., Lee, M. H., Rathore, M. G., Bode, A. M., Ashida, H., Lippman, S. M. & Dong, Z., Oct 1 2018, In : Cancer Prevention Research. 11, 10, p. 607-619 13 p.

Research output: Contribution to journalArticle

Angelica
Chalcones
Phosphatidylinositol 3-Kinases
Melanoma
Apoptosis
2 Citations (Scopus)

Therapies based on targeting Epstein-Barr virus lytic replication for EBV-associated malignancies

Li, H., Hu, J., Luo, X., Bode, A. M., Dong, Z. & Cao, Y., Jul 1 2018, In : Cancer Science. 109, 7, p. 2101-2108 8 p.

Research output: Contribution to journalReview article

Open Access
Virus Replication
Human Herpesvirus 4
Neoplasms
Therapeutics
Carcinogenesis
3 Citations (Scopus)

TRAF1 is critical for regulating the BRAF/MEK/ERK pathway in non–small cell lung carcinogenesis

Wang, Q., Gao, G., Zhang, T., Yao, K., Chen, H., Park, M. H., Yamamoto, H., Wang, K., Ma, W., Malakhova, M., Bode, A. M. & Dong, Z., Jul 15 2018, In : Cancer Research. 78, 14, p. 3982-3994 13 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Non-Small Cell Lung Carcinoma
Lung Neoplasms
Carcinogenesis
6 Citations (Scopus)

Veratramine modulates AP-1-dependent gene transcription by directly binding to programmable DNA

Bai, F., Liu, K., Li, H., Wang, J., Zhu, J., Hao, P., Zhu, L., Zhang, S., Shan, L., Ma, W-Y., Bode, A. M., Zhang, W., Li, H. & Dong, Z., Jan 25 2018, In : Nucleic acids research. 46, 2, p. 546-557 12 p.

Research output: Contribution to journalArticle

Open Access
Transcription Factor AP-1
DNA
Genes
Transcription Factors
veratramine
2017
7 Citations (Scopus)

ADA-07 suppresses solar ultraviolet–induced skin carcinogenesis by directly inhibiting TOPK

Gao, G., Zhang, T., Wang, Q., Reddy, K., Chen, H., Yao, K., Wang, K., Roh, E., Zykova, T., Ma, W., Ryu, J., Curiel-Lewandrowski, C., Alberts, D., Dickinson, S. E., Bode, A. M., Xing, Y. & Dong, Z., Sep 1 2017, In : Molecular Cancer Therapeutics. 16, 9, p. 1843-1854 12 p.

Research output: Contribution to journalArticle

Protein Kinases
Carcinogenesis
Skin Neoplasms
Protein Kinase Inhibitors
Skin
10 Citations (Scopus)

A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo

Shin, S. H., Lim, D. Y., Reddy, K., Malakhova, M., Liu, F., Wang, T., Song, M., Chen, H., Bae, K. B., Ryu, J., Liu, K., Lee, M. H., Bode, A. M. & Dong, Z., Nov 1 2017, In : EBioMedicine. 25, p. 22-31 10 p.

Research output: Contribution to journalArticle

Transcription Factor 7-Like 2 Protein
Catenins
Colorectal Neoplasms
Molecules
Growth
7 Citations (Scopus)

Chemoprevention of Colorectal Cancer by Artocarpin, a Dietary Phytochemical from Artocarpus heterophyllus

Sun, G., Zheng, Z., Lee, M. H., Xu, Y., Kang, S., Dong, Z., Wang, M., Gu, Z., Li, H. & Chen, W., May 3 2017, In : Journal of agricultural and food chemistry. 65, 17, p. 3474-3480 7 p.

Research output: Contribution to journalArticle

Artocarpus
Artocarpus heterophyllus
chemoprevention
Chemoprevention
Phytochemicals
9 Citations (Scopus)

Circulating tumor cells: Moving biological insights into detection

Chen, L., Bode, A. M. & Dong, Z., Jan 1 2017, In : Theranostics. 7, 10, p. 2606-2619 14 p.

Research output: Contribution to journalReview article

Circulating Neoplastic Cells
Cell Biology
Biopsy
Technology
1 Citation (Scopus)

Coumestrol epigenetically suppresses cancer cell proliferation: Coumestrol is a natural haspin kinase inhibitor

Kim, J. E., Lee, S-Y., Jang, M., Choi, H. K., Kim, J. H., Chen, H., Lim, T. G., Dong, Z. & Lee, K. W., Oct 24 2017, In : International journal of molecular sciences. 18, 10, 2228.

Research output: Contribution to journalArticle

Coumestrol
Cell proliferation
inhibitors
Phosphotransferases
cancer
1 Citation (Scopus)

ERK1 Directly Interacts With JNK1 Leading to Regulation of JNK1/c-Jun Activity and Cell Transformation

Kang, B. S., Hwang, Y. J. & Dong, Z., Aug 1 2017, In : Journal of Cellular Biochemistry. 118, 8, p. 2357-2370 14 p.

Research output: Contribution to journalArticle

Phosphorylation
Mitogen-Activated Protein Kinases
Tissue
Liver Neoplasms
Crosstalk

Functional PIN1 promoter polymorphisms associated with risk of nasopharyngeal carcinoma in Southern Chinese populations

Zeng, L., Luo, S., Li, X., Lu, M., Li, H., Li, T., Wang, G., Lyu, X., Jia, W., Dong, Z., Jiang, Q., Shen, Z., Huang, G. L. & He, Z., Dec 1 2017, In : Scientific reports. 7, 1, 4593.

Research output: Contribution to journalArticle

Haplotypes
Population
Single Nucleotide Polymorphism
Genotype
Incidence
5 Citations (Scopus)

Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC

Kim, D. J., Lee, M. H., Liu, K. D., Lim, D. Y., Roh, E., Chen, H., Kim, S. H., Shim, J. H., Kim, M. O., Li, W., Ma, F., Fredimoses, M., Bode, A. M. & Dong, Z., Nov 1 2017, In : Carcinogenesis. 38, 11, p. 1136-1146 11 p., bgx082.

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Squamous Cell Carcinoma
Melanoma
Skin
Skin Neoplasms
3 Citations (Scopus)

hMAGEA2 promotes progression of breast cancer by regulating Akt and Erk1/2 pathways

Park, S., Sung, Y., Jeong, J., Choi, M., Lee, J., Kwon, W., Jang, S., Park, S. J., Kim, H. S., Lee, M. H., Kim, D. J., Liu, K., Kim, S. H., Dong, Z., Ryoo, Z. Y. & Kim, M. O., Jan 1 2017, In : Oncotarget. 8, 23, p. 37115-37127 13 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Breast Neoplasms
Heterografts
Cell Line
Neoplasms
2 Citations (Scopus)

hYSK1 promotes cancer cell proliferation and migration through negative regulation of p16INK4a under hypoxic conditions

Lee, M. H., Dong, Z., Surh, Y. J. & Choi, B. Y., Jan 1 2017, In : Oncotarget. 8, 51, p. 89072-89085 14 p.

Research output: Contribution to journalArticle

Cell Movement
Matrix Metalloproteinase 2
Cell Proliferation
Neoplasms
Protein Array Analysis
4 Citations (Scopus)

LTA4H regulates cell cycle and skin carcinogenesis

Oi, N., Yamamoto, H., Langfald, A., Bai, R., Lee, M. H., Bode, A. M. & Dong, Z., Jul 1 2017, In : Carcinogenesis. 38, 7, p. 728-737 10 p., bgx049.

Research output: Contribution to journalArticle

Cell Cycle
Carcinogenesis
Skin Neoplasms
Skin
Cell Cycle Resting Phase
25 Citations (Scopus)

Molecular mechanisms of green tea polyphenols with protective effects against skin photoaging

Roh, E., Kim, J. E., Kwon, J. Y., Park, J. S., Bode, A. M., Dong, Z. & Lee, K. W., May 24 2017, In : Critical Reviews in Food Science and Nutrition. 57, 8, p. 1631-1637 7 p.

Research output: Contribution to journalArticle

photoaging
Skin Aging
Skin effect
Polyphenols
green tea
14 Citations (Scopus)

Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production

Yu, X., Li, W., Deng, Q., You, S., Liu, H., Peng, S., Liu, X., Lu, J., Luo, X., Yang, L., Tang, M., Weng, X., Yi, W., Liu, W., Wu, S., Ding, Z., Feng, T., Zhou, J., Fan, J., Bode, A. M. & 3 others, Dong, Z., Liu, J. & Cao, Y., May 1 2017, In : Molecular Carcinogenesis. 56, 5, p. 1414-1426 13 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Growth
Neoplasms
Endothelial Cells
neoalbaconol

Pairing Cancer Biomarkers to Biomedicine

Shin, S. H. & Dong, Z., Nov 1 2017, In : EBioMedicine. 25, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Antibodies, Monoclonal, Humanized
beta Catenin
Tumor Biomarkers
Antineoplastic Agents
Monoclonal Antibodies
9 Citations (Scopus)

Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer

Xiao, T., Zhu, J. J., Huang, S., Peng, C., He, S., Du, J., Hong, R., Chen, X., Bode, A. M., Jiang, W., Dong, Z. & Zheng, D., May 18 2017, In : Oncogene. 36, 20, p. 2835-2845 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 3
Skin Neoplasms
Serine
NFATC Transcription Factors
Phosphorylation

RSK2 phosphorylates T-bet to attenuate colon cancer metastasis and growth

Yao, K., Peng, C., Zhang, Y., Zykova, T. A., Lee, M. H., Lee, S. Y., Rao, E., Chen, H., Ryu, J., Wang, L., Zhang, Y., Gao, G., He, W., Ma, W. Y., Liu, K., Bode, A. M., Dong, Z., Li, B. & Dong, Z., Nov 28 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 48, p. 12791-12796 6 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Neoplasm Metastasis
Growth
Knockout Mice
Phosphorylation
1 Citation (Scopus)

Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells

Bae, K. B., Yu, D. H., Lee, K. Y., Yao, K., Ryu, J., Lim, D. Y., Zykova, T. A., Kim, M. O., Bode, A. M. & Dong, Z., Dec 12 2017, In : Stem Cell Reports. 9, 6, p. 2050-2064 15 p.

Research output: Contribution to journalArticle

Phosphorylation
JNK Mitogen-Activated Protein Kinases
Protein Stability
Stem cells
Induced Pluripotent Stem Cells
2 Citations (Scopus)

Small molecule inhibitors of mesotrypsin from a structurebased docking screen

Kayode, O., Huang, Z., Soares, A. S., Caulfield, T. R., Dong, Z., Bode, A. M. & Radisky, E. S., May 1 2017, In : PLoS One. 12, 5, e0176694.

Research output: Contribution to journalArticle

Diminazene
diminazene
crystal structure
Crystal structure
Trypsin
2 Citations (Scopus)

The CUG-translated WT1, not AUG-WT1, is an oncogene

Lee, K. Y., Jeon, Y. J., Kim, H. G., Ryu, J., Lim, D. Y., Jung, S. K., Yu, D. H., Chen, H., Bode, A. M. & Dong, Z., Dec 1 2017, In : Carcinogenesis. 38, 12, p. 1228-1240 13 p.

Research output: Contribution to journalArticle

Wilms Tumor
Oncogenes
Neoplasms
Histone Deacetylase 1
Wilms' Tumor Genes
1 Citation (Scopus)

The prolyl isomerase pin1 is a novel target of 6,7,40-trihydroxyisoflavone for suppressing esophageal cancer growth

Lim, T. G., Lee, S. Y., Duan, Z., Lee, M. H., Chen, H., Liu, F., Liu, K., Jung, S. K., Kim, D. J., Bode, A. M., Lee, K. W. & Dong, Z., May 1 2017, In : Cancer Prevention Research. 10, 5, p. 308-318 11 p.

Research output: Contribution to journalArticle

Peptidylprolyl Isomerase
Esophageal Neoplasms
Isoflavones
Growth
Proteins