Find Research Outputs

Search concepts
Selected Filters
2018

Lipoprotein(a) and abdominal aortic aneurysm risk: The Atherosclerosis Risk in Communities study

Kubota, Y., Folsom, A. R., Ballantyne, C. M. & Tang, W. Jan 1 2018 In : Atherosclerosis. 268, p. 63-67 5 p.

Research output: Research - peer-reviewArticle

Lipoprotein(a)
Abdominal Aortic Aneurysm
Atherosclerosis
African Americans
LDL Cholesterol

Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC)

Garg, P. K., Norby, F. L., Polfus, L. M., Boerwinkle, E., Gibbs, R. A., Grove, M. L., Folsom, A. R., Garimella, P. S., Matsushita, K., Hoogeveen, R. C. & Ballantyne, C. M. Jan 1 2018 In : Atherosclerosis. 268, p. 12-18 7 p.

Research output: Research - peer-reviewArticle

1-Alkyl-2-acetylglycerophosphocholine Esterase
Peripheral Arterial Disease
Atherosclerosis
Confidence Intervals
African Americans
1 Citations

Prospective study of lung function and abdominal aortic aneurysm risk: The Atherosclerosis Risk in Communities study

Kubota, Y., Folsom, A. R., Matsushita, K., Couper, D. & Tang, W. Jan 1 2018 In : Atherosclerosis. 268, p. 225-230 6 p.

Research output: Research - peer-reviewArticle

Abdominal Aortic Aneurysm
Atherosclerosis
Prospective Studies
Lung
Chronic Obstructive Pulmonary Disease
2017
1 Citations

Accuracy of Self-Reported Heart Failure. The Atherosclerosis Risk in Communities (ARIC) Study

Camplain, R., Kucharska-Newton, A., Loehr, L., Keyserling, T. C., Layton, J. B., Wruck, L., Folsom, A. R., Bertoni, A. G. & Heiss, G. Nov 1 2017 In : Journal of Cardiac Failure. 23, 11, p. 802-808 7 p.

Research output: Research - peer-reviewArticle

Atherosclerosis
Heart Failure
Physicians
Self Report
Hospitalization

Association of Cardiovascular Health With Subclinical Disease and Incident Events: The Multi-Ethnic Study of Atherosclerosis

Polonsky, T. S., Ning, H., Daviglus, M. L., Liu, K., Burke, G. L., Cushman, M., Eng, J., Folsom, A. R., Lutsey, P. L., Nettleton, J. A., Post, W. S., Sacco, R. L., Szklo, M. & Lloyd-Jones, D. M. Mar 1 2017 In : Journal of the American Heart Association. 6, 3, e004894

Research output: Research - peer-reviewArticle

Atherosclerosis
Health
Cardiovascular Diseases
Carotid Intima-Media Thickness
Coronary Vessels
4 Citations

Association of educational attainment with lifetime risk of cardiovascular disease the atherosclerosis risk in communities study

Kubota, Y., Heiss, G., Maclehose, R. F., Roetker, N. S. & Folsom, A. R. Aug 1 2017 In : JAMA Internal Medicine. 177, 8, p. 1165-1172 8 p.

Research output: Research - peer-reviewArticle

Atherosclerosis
Cardiovascular Diseases
African Americans
Education
Mississippi
7 Citations

Association of traditional cardiovascular risk factors with venous thromboembolism

Mahmoodi, B. K. , Cushman, M. , Næss, I. A. , Allison, M. A. , Bos, W. J. , Brækkan, S. K. , Cannegieter, S. C. , Gansevoort, R. T. , Gona, P. N. , Hammerstrøm, J. , Hansen, J. B. , Heckbert, S. , Holst, A. G. , Lakoski, S. G. , Lutsey, P. L. , Manson, J. A. E. , Martin, L. W. , Matsushita, K. , Meijer, K. , Overvad, K. & 8 others Prescott, E., Puurunen, M., Rossouw, J. E., Sang, Y., Severinsen, M. T., Ten Berg, J., Folsom, A. R. & Zakai, N. A. Jan 3 2017 In : Circulation. 135, 1, p. 7-16 10 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Confidence Intervals
Blood Pressure
Cardiovascular Diseases
Smoking
2 Citations

Cardiovascular Event Prediction by Machine Learning: The Multi-Ethnic Study of Atherosclerosis

Ambale-Venkatesh, B., Yang, X., Wu, C. O., Liu, K., Hundley, W. G., McClelland, R., Gomes, A. S., Folsom, A. R., Shea, S., Guallar, E., Bluemke, D. A. & Lima, J. A. C. Oct 13 2017 In : Circulation Research. 121, 9, p. 1092-1101 10 p.

Research output: Research - peer-reviewArticle

Atherosclerosis
Cardiovascular Diseases
Biomarkers
Machine Learning
Population
1 Citations

Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

Song, C. , Burgess, S. , Eicher, J. D. , O'Donnell, C. J. , Johnson, A. D. , Huang, J. , Sabater-Lleal, M. , Asselbergs, F. W. , Tregouet, D. , Shin, S. Y. , Ding, J. , Baumert, J. , Oudot-Mellakh, T. , Folkersen, L. , Smith, N. L. , Williams, S. M. , Ikram, M. A. , Kleber, M. E. , Becker, D. M. , Truong, V. & 472 others Mychaleckyj, J. C., Tang, W., Yang, Q., Sennblad, B., Moore, J. H., Williams, F. M. K., Dehghan, A., Silbernagel, G., Schrijvers, E. M. C., Smith, S., Karakas, M., Tofler, G. H., Silveira, A., Navis, G. J., Lohman, K., Chen, M. H., Peters, A., Goel, A., Hopewell, J. C., Chambers, J. C., Saleheen, D., Lundmark, P., Psaty, B. M., Strawbridge, R. J., Boehm, B. O., Carter, A. M., Meisinger, C., Peden, J. F., Bis, J. C., McKnight, B., Öhrvik, J., Taylor, K., Franzosi, M. G., Seedorf, U., Collins, R., Franco-Cereceda, A., Syvänen, A. C., Goodall, A. H., Yanek, L. R., Cushman, M., Müller-Nurasyid, M., Folsom, A. R., Basu, S., Matijevic, N., van Gilst, W. H., Kooner, J. S., Danesh, J., Clarke, R., Meigs, J. B., Kathiresan, S., Reilly, M. P., Klopp, N., Harris, T. B., Winkelmann, B. R., Grant, P. J., Hillege, H. L., Watkins, H., Spector, T. D., Becker, L. C., Tracy, R. P., März, W., Uitterlinden, A. G., Eriksson, P., Cambien, F., Morange, P. E., Koenig, W., Soranzo, N., van der Harst, P., Liu, Y., Hamsten, A., Ehret, G. B., Munroe, P. B., Rice, K. M., Bochud, M., Chasman, D. I., Smith, A. V., Tobin, M. D., Verwoert, G. C., Hwang, S. J., Pihur, V., Vollenweider, P., O'Reilly, P. F., Amin, N., Bragg-Gresham, J. L., Teumer, A., Glazer, N. L., Launer, L., Zhao, J. H., Aulchenko, Y., Heath, S., Sõber, S., Parsa, A., Luan, J., Arora, P., Zhang, F., Lucas, G., Hicks, A. A., Jackson, A. U., Tanaka, T., Wild, S. H., Rudan, I., Igl, W., Milaneschi, Y., Parker, A. N., Fava, C., Fox, E. R., Kumari, M., Go, M. J., Linda Kao, W. H., Sjögren, M., Vinay, D. G., Alexander, M., Tabara, Y., Shaw-Hawkins, S., Whincup, P. H., Shi, G., Kuusisto, J., Tayo, B., Seielstad, M., Sim, X., Nguyen, K. D. H., Lehtimäki, T., Matullo, G., Wu, Y., Gaunt, T. R., Onland-Moret, N. C., Cooper, M. N., Platou, C. G. P., Org, E., Hardy, R., Dahgam, S., Palmen, J., Vitart, V., Braund, P. S., Kuznetsova, T., Uiterwaal, C. S. P. M., Adeyemo, A., Palmas, W., Campbell, H., Ludwig, B., Tomaszewski, M., Tzoulaki, I., Palmer, N. D., Aspelund, T., Garcia, M., Chang, Y. P. C., O'Connell, J. R., Steinle, N. I., Grobbee, D. E., Arking, D. E., Kardia, S. L., Morrison, A. C., Hernandez, D., Najjar, S., McArdle, W. L., Hadley, D., Brown, M. J., Connell, J. M., Hingorani, A. D., Day, I. N. M., Lawlor, D. A., Beilby, J. P., Lawrence, R. W., Ongen, H., Dreisbach, A. W., Li, Y., Young, J. H., Kähönen, M., Viikari, J., Adair, L. S., Lee, N. R., Olden, M., Pattaro, C., Hoffman Bolton, J. A., Köttgen, A., Bergmann, S., Mooser, V., Chaturvedi, N., Frayling, T. M., Islam, M., Jafar, T. H., Erdmann, J., Kulkarni, S. R., Bornstein, S. R., Grässler, J., Groop, L., Voight, B. F., Kettunen, J., Howard, P., Taylor, A., Guarrera, S., Ricceri, F., Emilsson, V., Plump, A., Barroso, I., Khaw, K. T., Weder, A. B., Hunt, S. C., Sun, Y. V., Bergman, R. N., Collins, F. S., Bonnycastle, L. L., Scott, L. J., Stringham, H. M., Peltonen, L., Perola, M., Vartiainen, E., Brand, S. M., Staessen, J. A., Wang, T. J., Burton, P. R., Artigas, M. S., Dong, Y., Snieder, H., Wang, X., Zhu, H., Lohman, K. K., Rudock, M. E., Heckbert, S. R., Wiggins, K. L., Doumatey, A., Shriner, D., Veldre, G., Viigimaa, M., Kinra, S., Prabhakaran, D., Tripathy, V., Langefeld, C. D., Rosengren, A., Thelle, D. S., Corsi, A. M., Singleton, A., Forrester, T., Hilton, G., McKenzie, C. A., Salako, T., Iwai, N., Kita, Y., Ogihara, T., Ohkubo, T., Okamura, T., Ueshima, H., Umemura, S., Eyheramendy, S., Meitinger, T., Wichmann, H. E., Cho, Y. S., Kim, H. L., Lee, J. Y., Scott, J., Sehmi, J. S., Zhang, W., Hedblad, B., Nilsson, P., Smith, G. D., Wong, A., Narisu, N., Stančáková, A., Raffel, L. J., Yao, J., Schwartz, S. M., Arfan Ikram, M., Longstreth, W. T., Mosley, T. H., Seshadri, S., Shrine, N. R. G., Wain, L. V., Morken, M. A., Swift, A. J., Laitinen, J., Prokopenko, I., Zitting, P., Cooper, J. A., Humphries, S. E., Rasheed, A., Bakker, S. J. L., Janipalli, C. S., Mani, K. R., Yajnik, C. S., Mattace-Raso, F. U. S., Oostra, B. A., Demirkan, A., Isaacs, A., Rivadeneira, F., Lakatta, E. G., Orru, M., Scuteri, A., Ala-Korpela, M., Kangas, A. J., Lyytikäinen, L. P., Soininen, P., Tukiainen, T., Würtz, P., Ong, R. T. H., Dörr, M., Kroemer, H. K., Völker, U., Völzke, H., Galan, P., Hercberg, S., Lathrop, M., Zelenika, D., Deloukas, P., Mangino, M., Zhai, G., Meschia, J. F., Nalls, M. A., Sharma, P., Terzic, J., Kumar, M. V. K., Denniff, M., Zukowska-Szczechowska, E., Wagenknecht, L. E., Fowkes, F. G. R., Charchar, F. J., Schwarz, P. E. H., Hayward, C., Guo, X., Rotimi, C., Bots, M. L., Brand, E., Samani, N. J., Polasek, O., Talmud, P. J., Nyberg, F., Kuh, D., Laan, M., Hveem, K., Palmer, L. J., van der Schouw, Y. T., Casas, J. P., Mohlke, K. L., Vineis, P., Raitakari, O., Ganesh, S. K., Wong, T. Y., Shyong Tai, E., Cooper, R. S., Laakso, M., Rao, D. C., Morris, R. W., Dominiczak, A. F., Kivimaki, M., Marmot, M. G., Miki, T., Chandak, G. R., Coresh, J., Navis, G., Salomaa, V., Han, B. G., Zhu, X., Melander, O., Ridker, P. M., Bandinelli, S., Gyllensten, U. B., Wright, A. F., Wilson, J. F., Ferrucci, L., Farrall, M., Tuomilehto, J., Pramstaller, P. P., Elosua, R., Sijbrands, E. J. G., Altshuler, D., Loos, R. J. F., Gieger, C., Meneton, P., Wareham, N. J., Gudnason, V., Rotter, J. I., Rettig, R., Uda, M., Strachan, D. P., Witteman, J. C. M., Hartikainen, A. L., Beckmann, J. S., Boerwinkle, E., Vasan, R. S., Boehnke, M., Larson, M. G., Järvelin, M. R., Abecasis, G. R., Chakravarti, A., Elliott, P., van Duijn, C. M., Newton-Cheh, C., Levy, D., Caulfield, M. J., Johnson, T., van der Lugt, A., Shuldiner, A. R., Hofman, A., Kraja, A. T., Uitterlinden, A., Ziegler, A., Newman, A. B., Schillert, A., Oostra, B., Thorsson, B., Mitchell, B. D., Fox, C. S., White, C. C., Ballantyne, C., Duijn, C. V., Herrington, D. M., O'Leary, D. H., Siscovick, D. S., Couper, D. J., Halperin, E., Stoegerer, E. M., Ernst, F., Krestin, G. P., Homuth, G., Heiss, G., Usala, G., Eiriksdottir, G., Shen, H., Erich Wichmann, H., Schmidt, H., Borecki, I. B., Markus, H. S., Witteman, J., Lüdemann, J., Huffman, J. E., Murabito, J. M., Thiery, J., Seissler, J., Massaro, J. M., Polak, J. F., Cunningham, J., North, K., Petrovic, K. E., Rice, K., Adrienne Cupples, L., Bielak, L. F., Launer, L. J., Andrade, M. D., Feitosa, M. F., Kavousi, M., Sitzer, M., Oudkerk, M., Province, M. A., Nalls, M., Franceschini, N., Peyser, P. A., Wolf, P. A., Zhang, Q., Wild, P. S., Schnabel, R. B., D'Agostino, R. B., Chilukoti, R. K., Schmidt, R., Sanna, S., Demissie, S., Sigurdsson, S., Blankenberg, S., Bevan, S., Elias-Smale, S. E., Zeller, T., Illig, T., Münzel, T., Howard, T. D., Hoffmann, U., Schminke, U., Nambi, V., Post, W. S., Rathmann, W., Li, X., Cheng, Y. C., CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group Jun 1 2017 In : Journal of the American Heart Association. 6, 6, e004918

Research output: Research - peer-reviewArticle

Plasminogen Activator Inhibitor 1
Coronary Disease
Odds Ratio
Mendelian Randomization Analysis
Genome-Wide Association Study
2 Citations

Contemporary Assessment of Left Ventricular Diastolic Function in Older Adults: The Atherosclerosis Risk in Communities Study

Shah, A. M., Claggett, B., Kitzman, D., Biering-Sørensen, T., Jensen, J. S., Cheng, S., Matsushita, K., Konety, S., Folsom, A. R., Mosley, T. H., Wright, J. D., Heiss, G. & Solomon, S. D. Jan 31 2017 In : Circulation. 135, 5, p. 426-439 14 p.

Research output: Research - peer-reviewArticle

Left Ventricular Function
Atherosclerosis
Heart Failure
Guidelines
Population

Diabetes-related factors and abdominal aortic aneurysm events: The Atherosclerotic Risk in Communities Study

Kubota, Y., Folsom, A. R., Pankow, J. S., Wagenknecht, L. E. & Tang, W. Jan 1 2017 (Accepted/In press) In : Annals of Epidemiology.

Research output: Research - peer-reviewArticle

Abdominal Aortic Aneurysm
Leptin
Confidence Intervals
Glucose
Fasting
1 Citations
Peripheral Arterial Disease
Atherosclerosis
Incidence
Food
Meat
4 Citations

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney, A. , Kesselmeier, M. , Jall, S. , Volckmar, A. L. , Föcker, M. , Antel, J. , Heid, I. M. , Winkler, T. W. , Grant, S. F. A. , Guo, Y. , Bergen, A. W. , Kaye, W. , Berrettini, W. , Hakonarson, H. , Herpertz-Dahlmann, B. , De Zwaan, M. , Herzog, W. , Ehrlich, S. , Zipfel, S. , Egberts, K. M. & 534 others Adan, R., Brandys, M., Van Elburg, A., Boraska Perica, V., Müller, T. D., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., Perica, V. B., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., Tozzi, F., Iezebrink, K., Hebebrand, J., Gorwood, P., Adan, R. A. H., Kas, M. J. H., Favaro, A., Santonastaso, P., Fernández-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori-Helkamaa, A., Van Furth, E. F., Slof-Op’t Landt, M. C. T., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Komaki, G., Ando, T., Inoko, H., Esko, T., Fischer, K., Männik, K., Metspalu, A., Baker, J. H., Cone, R. D., Dackor, J., DeSocio, J. E., Hilliard, C. E., O’Toole, J. K., Pantel, J., Szatkiewicz, J. P., Taico, C., Zerwas, S., Trace, S. E., Davis, O. S. P., Helder, S., Bühren, K., Burghardt, R., de Zwaan, M., Egberts, K., Ehrlich, S., Herpertz-Dahlmann, B., Herzog, W., Imgart, H., Scherag, A., Scherag, S., Zipfel, S., Boni, C., Ramoz, N., Versini, A., Brandys, M. K., Danner, U. N., de Kove, C., Hendriks, J., Koeleman, B. P. C., Ophoff, R. A., Strengman, E., van Elburg, A. A., Bruson, A., Clementi, M., Degortes, D., Forzan, M., Tenconi, E., Docampo, E., Jiménez-Murcia, G. E. S., Lissowska, J., Rajewski, A., Szeszenia-Dabrowska, N., Slopien, A., Hauser, J., Karhunen, L., Meulenbelt, I., Slagboom, P. E., Tortorella, A., Maj, M., Dedoussis, G., Dikeos, D., Gonidakis, F., Tziouvas, K., Tsitsika, A., Papezova, H., Slachtova, L., Martaskova, D., Kennedy, J. L., Levitan, R. D., Yilmaz, Z., Huemer, J., Koubek, D., Merl, E., Wagner, G., Lichtenstein, P., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Cichon, S., Giegling, I., Herms, S., Rujescu, D., Schreiber, S., Wichmann, H. E., Christian, D., Sladek, R., Gambaro, G., Soranzo, N., Julia, A., Marsal, S., Rabionet, R., Gaborieau, V., Dick, D. M., Palotie, A., Ripatti, S., Widén, E., Andreassen, O. A., Espeseth, T., Lundervold, A., Reinvang, I., Steen, V. M., Le Hellard, S., Mattingsdal, M., Ntalla, I., Bencko, V., Foretova, L., Janout, V., Navratilova, M., Gallinger, S., Pinto, D., Scherer, S. W., Aschauer, H., Carlberg, L., Schosser, A., Alfredsson, L., Ding, B., Klareskog, L., Padyukov, L., Finan, C., Kalsi, G., Roberts, M., Logan, D. W., Peltonen, L., Ritchie, G. R. S., Barrett, J. C., Estivill, X., Hinney, A., Sullivan, P. F., Collier, D. A., Zeggini, E., Bulik, C. M., Anderson, C. A., Barrett, J. C., Floyd, J. A. B., Franklin, C. S., McGinnis, R., Soranzo, N., Zeggini, E., Sambrook, J., Stephens, J., Ouwehand, W. H., McArdle, W. L., Ring, S. M., Strachan, D. P., Alexander, G., Bulik, C. M., Collier, D. A., Conlon, P. J., Dominiczak, A., Duncanson, A., Hill, A., Langford, C., Lord, G., Maxwell, A. P., Morgan, L., Peltonen, L., Sandford, R. N., Sheerin, N., Vannberg, F. O., Blackburn, H., Chen, W. M., Edkins, S., Gillman, M., Gray, E., Hunt, S. E., Nengut, S. G., Potter, S., Rich, S. S., Simpkin, D., Whittaker, P., Adair, L. S., Ang, W., Atalay, M., van Beijsterveldt, T., Bergen, N., Benke, K., Berry, D. J., Boomsma, D. I., Bradfield, J. P., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Das, S., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Evans, D. M., Feenstra, B., Flexeder, C., Frayling, T., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M., Grant, S. F., Groen-Blokhuis, M., Goh, L. K., Guxens, M., Hakonarson, H., Hattersley, A. T., Haworth, C. M., Hadley, D., Hebebrand, J., Heinrich, J., Hinney, A., Hirschhorn, J. N., Hocher, B., Holloway, J. W., Holst, C., Hottenga, J. J., Horikoshi, M., Huikari, V., Hypponen, E., Iñiguez, C., Jaddoe, V. W., Jarvelin, M. R., Kaakinen, M., Kilpeläinen, T. O., Kirin, M., Kowgier, M., Lakka, H. M., Lakka, T. A., Lange, L. A., Lawlor, D. A., Lehtimäki, T., Lewin, A., Lindgren, C., Lindi, V., Maggi, R., Marsh, J., McCarthy, M. I., Melbye, M., Middeldorp, C., Millwood, I., Mohlke, K. L., Mook-Kanamori, D. O., Murray, J. C., Nivard, M., Nohr, E. A., Ntalla, I., Oken, E., Ong, K. K., O'Reilly, P. F., Palmer, L. J., Panoutsopoulou, K., Pararajasingham, J., Pearson, E. R., Pennell, C. E., Power, C., Price, T. S., Prokopenko, I., Raitakari, O. T., Rodriguez, A., Salem, R. M., Saw, S. M., Scherag, A., Sebert, S., Siitonen, N., Simell, O., Sørensen, T. I., Sovio, U., Pourcain, B. S., Strachan, D. P., Sunyer, J., Taal, H. R., Teo, Y. Y., Thiering, E., Tiesler, C., Timpson, N. J., Uitterlinden, A. G., Valcárcel, B., Warrington, N. M., White, S., Widén, E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zeggini, E., Elks, C. E., Perry, J. R., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Hottenga, J. J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F., Smith, A. V., Stolk, L., van Wingerden, S. H., Zhao, J. H., Albrecht, E., Corre, T., Ingelsson, E., Hayward, C., Magnusson, P. K., Smith, E. N., Ulivi, S., Warrington, M., Zgaga, L., Alavere, H., Amin, N., Aspelund, T., Bandinelli, S., Barroso, I., Berenson, G. S., Bergmann, S., Blackburn, H., Boerwinkle, E., Buring, J. E., Busonero, F., Campbell, H., Chanock, S. J., Chen, W., Cornelis, M. C., Couper, D., Coviello, A. D., d'Adamo, P., de Faire, U., de Geus, E. J., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Eriksson, J., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Geller, F., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hofman, A., Hu, F. B., Illig, T., Järvelin, M. R., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kilpeläinen, T. O., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., Martin, N. G., McArdle, W. L., Melbye, M., Mooser, V., Murray, J. C., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Palmer, L. J., Palotie, A., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Pouta, A., Porcu, E., Rafnar, T., Rice, J. P., Ring, S. M., Rivadeneira, F., Rudan, I., Sala, C., Salomaa, V., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V., Shuldiner, A. R., Soranzo, N., Sovio, U., Srinivasan, S. R., Strachan, D. P., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., van Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D. M., Weedon, M. N., Wichmann, H. E., Willemsen, G., Wilson, J. F., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Montgomery, G. W., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Uitterlinden, A. G., Widen, E., Murabito, J. M., Ong, K. K., Murray, A., Brandt, H., Crawford, S., Crow, S., Fichter, M. M., Halmi, K. A., Johnson, C., Kaplan, A. S., La Via, M., Mitchell, J., Strober, M., Rotondo, A., Treasure, J., Woodside, D. B., Bulik, C. M., Keel, P., Klump, K. L., Lilenfeld, L., Thornton, L. M., Plotnicov, K., Bergen, A. W., Berrettini, W., Kaye, W., Magistretti, P., GCAN, WTCCC3, GIANT, EGG, Price Foundation Collaborative Group & Children’s Hospital of Philadelphia/Price Foundation Feb 1 2017 In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Research - peer-reviewArticle

Genetic Loci
Anorexia Nervosa
Body Mass Index
Genome-Wide Association Study
Meta-Analysis

Factors related to diff erences in retention among african American and white participants in the atherosclerosis risk in communities study (ARIC ) prospective cohort: 1987-2013

George, K. M., Folsom, A. R., Kucharska-Newton, A., Mosley, T. H. & Heiss, G. Dec 1 2017 In : Ethnicity and Disease. 27, 1, p. 31-38 8 p.

Research output: Research - peer-reviewArticle

African Americans
Atherosclerosis
Cohort Studies
Prospective Studies
Social Class

Failure to replicate thrombomodulin genetic variant predictors of venous thromboembolism in African Americans

Folsom, A. R., Roetker, N. S., Kelley, S. T., Tang, W. & Pankratz, N. Aug 3 2017 In : Blood. 130, 5, p. 688-690 3 p.

Research output: Research - peer-reviewLetter

Thrombomodulin
Venous Thromboembolism
African Americans

Galectin-3 and incidence of atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study

Fashanu, O. E., Norby, F. L., Aguilar, D., Ballantyne, C. M., Hoogeveen, R. C., Chen, L. Y., Soliman, E. Z., Alonso, A. & Folsom, A. R. Oct 1 2017 In : American Heart Journal. 192, p. 19-25 7 p.

Research output: Research - peer-reviewArticle

Galectin 3
Atrial Fibrillation
Atherosclerosis
Incidence
Coronary Disease
Carotid Intima-Media Thickness
Fibrinogen
Atherosclerosis
Aptitude
Confounding Factors (Epidemiology)

Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels

Sennblad, B. , Basu, S. , Mazur, J. , Suchon, P. , Martinez-Perez, A. , Vlieg, A. V. H. , Truong, V. , Li, Y. , Gådin, J. R. , Tang, W. , Grossman, V. , de Haan, H. G. , Handin, N. , Silveira, A. , Souto, J. C. , Franco-Cereceda, A. , Morange, P. E. , Gagnon, F. , Soria, J. M. , Eriksson, P. & 7 others Hamsten, A., Maegdefessel, L., Rosendaal, F. R., Wild, P., Folsom, A. R., Trégouët, D. A. & Sabater-Lleal, M. 2017 In : Human Molecular Genetics. 26, 3, p. 637-649 13 p.

Research output: Research - peer-reviewArticle

Factor XI
Genome-Wide Association Study
Single Nucleotide Polymorphism
Partial Thromboplastin Time
Luciferases
2 Citations

Heart Failure Stages among Older Adults in the Community: The Atherosclerosis Risk in Communities Study

Shah, A. M., Claggett, B., Loehr, L. R., Chang, P. P., Matsushita, K., Kitzman, D., Konety, S., Kucharska-Newton, A., Sueta, C. A., Mosley, T. H., Wright, J. D., Coresh, J., Heiss, G., Folsom, A. R. & Solomon, S. D. Jan 17 2017 In : Circulation. 135, 3, p. 224-240 17 p.

Research output: Research - peer-reviewArticle

Atherosclerosis
Heart Failure
Stroke Volume
Hospitalization
Left Ventricular Dysfunction

Heart rate variability and lifetime risk of cardiovascular disease: the Atherosclerosis Risk in Communities Study

Kubota, Y., Chen, L. Y., Whitsel, E. A. & Folsom, A. R. Oct 1 2017 In : Annals of Epidemiology. 27, 10, p. 619-625.e2

Research output: Research - peer-reviewArticle

Atherosclerosis
Cardiovascular Diseases
Heart Rate
Life Tables
Coronary Disease

Hospitalization with infection and incident venous thromboembolism: The ARIC study

Cowan, L. T., Lutsey, P. L., Pankow, J. S., Cushman, M. & Folsom, A. R. Mar 1 2017 In : Thrombosis Research. 151, p. 74-78 5 p.

Research output: Research - peer-reviewArticle

Venous Thromboembolism
Atherosclerosis
Hospitalization
Infection
Cross-Over Studies
Protein C
Lipoproteins
Atherosclerosis
Genome
LDL Cholesterol
Cardiovascular Diseases
Population
Publications
Blood Glucose
Epidemiology
1 Citations

Kidney function, bone-mineral metabolism markers, and future risk of peripheral artery disease

Yang, C., Kwak, L., Ballew, S. H., Garimella, P. S., Jaar, B. G., Folsom, A. R., Heiss, G., Selvin, E., Lutsey, P. L., Coresh, J. & Matsushita, K. Dec 1 2017 In : Atherosclerosis. 267, p. 167-174 8 p.

Research output: Research - peer-reviewArticle

Peripheral Arterial Disease
Minerals
Kidney
Bone and Bones
Glomerular Filtration Rate

Midlife Systemic Inflammation, Late-Life White Matter Integrity, and Cerebral Small Vessel Disease: The Atherosclerosis Risk in Communities Study

Walker, K. A., Power, M. C., Hoogeveen, R. C., Folsom, A. R., Ballantyne, C. M., Knopman, D. S., Windham, B. G., Selvin, E., Jack, C. R. & Gottesman, R. F. Dec 1 2017 In : Stroke. 48, 12, p. 3196-3202 7 p.

Research output: Research - peer-reviewArticle

Cerebral Small Vessel Diseases
Cerebrovascular Disorders
Systemic Inflammatory Response Syndrome
Diffusion Tensor Imaging
Cerebral Infarction

Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study

Walker, K. A., Hoogeveen, R. C., Folsom, A. R., Ballantyne, C. M., Knopman, D. S., Windham, B. G., Jack, C. R. & Gottesman, R. F. Nov 28 2017 In : Neurology. 89, 22, p. 2262-2270 9 p.

Research output: Research - peer-reviewArticle

Sex Factors
Episodic Memory
Age Factors
Factor VIII
von Willebrand Factor
2 Citations

Physical Activity, Obesity, and Subclinical Myocardial Damage

Florido, R., Ndumele, C. E., Kwak, L., Pang, Y., Matsushita, K., Schrack, J. A., Lazo, M., Nambi, V., Blumenthal, R. S., Folsom, A. R., Coresh, J., Ballantyne, C. M. & Selvin, E. May 1 2017 In : JACC: Heart Failure. 5, 5, p. 377-384 8 p.

Research output: Research - peer-reviewArticle

Obesity
Troponin T
Heart Failure
Odds Ratio
Confidence Intervals
5 Citations

Physical Activity and Lifetime Risk of Cardiovascular Disease and Cancer

Kubota, Y., Evenson, K. R., MacLehose, R. F., Roetker, N. S., Joshu, C. E. & Folsom, A. R. Mar 27 2017 (Accepted/In press) In : Medicine and Science in Sports and Exercise.

Research output: Research - peer-reviewArticle

Cardiovascular Diseases
Exercise
Neoplasms
Life Tables
Health Status

Racial disparities in risks of stroke

Nadruz, W., Claggett, B., Henglin, M., Shah, A. M., Skali, H., Rosamond, W. D., Folsom, A. R., Solomon, S. D. & Cheng, S. May 25 2017 In : New England Journal of Medicine. 376, 21

Research output: Research - peer-reviewLetter

Relation of coagulation factor XI with incident coronary heart disease and stroke: The Cardiovascular Health Study

Appiah, D., Fashanu, O. E., Heckbert, S. R., Cushman, M., Psaty, B. M. & Folsom, A. R. Jul 1 2017 In : Blood Coagulation and Fibrinolysis. 28, 5, p. 389-392 4 p.

Research output: Research - peer-reviewArticle

Factor XI
Coronary Disease
Stroke
Myocardial Infarction
Health

Retinal microvascular signs and incidence of abdominal aortic aneurysm: The Atherosclerosis Risk in Communities Study

Folsom, A. R., Lutsey, P. L., Klein, R., Klein, B. E. & Tang, W. Dec 28 2017 (Accepted/In press) In : Ophthalmic Epidemiology. p. 1-4 4 p.

Research output: Research - peer-reviewArticle

Abdominal Aortic Aneurysm
Atherosclerosis
Incidence
Prospective Studies
Medical Record Linkage
1 Citations

Sickle cell trait is not associated with an increased risk of heart failure or abnormalities of cardiac structure and function

Bello, N. A. , Hyacinth, H. I. , Roetker, N. S. , Seals, S. R. , Naik, R. P. , Derebail, V. K. , Kshirsagar, A. V. , Key, N. S. , Wilson, J. G. , Correa, A. , Adams, R. J. , Egede, L. D. , Longstreth, W. T. , Choudhary, G. , Gee, B. E. , Hughes, A. L. , Shah, A. M. , Manson, J. E. , Allison, M. , Burke, G. L. & 5 others Folsom, A. R., Carty, C. L., Reiner, A. P., Solomon, S. D. & Konety, S. H. Feb 9 2017 In : Blood. 129, 6, p. 799-801 3 p.

Research output: Research - peer-reviewLetter

2 Citations

Taller height as a risk factor for venous thromboembolism: A Mendelian randomization meta-analysis

Roetker, N. S., Armasu, S. M., Pankow, J. S., Lutsey, P. L., Tang, W., Rosenberg, M. A., Palmer, T. M., Maclehose, R. F., Heckbert, S. R., Cushman, M., de Andrade, M. & Folsom, A. R. 2017 (Accepted/In press) In : Journal of Thrombosis and Haemostasis.

Research output: Research - peer-reviewArticle

Mendelian Randomization Analysis
Venous Thromboembolism
Meta-Analysis
Odds Ratio
Confidence Intervals

β-Thromboglobulin and incident cardiovascular disease risk: The Atherosclerosis Risk in Communities study

Kubota, Y., Alonso, A. & Folsom, A. R. Jul 1 2017 In : Thrombosis Research. 155, p. 116-120 5 p.

Research output: Research - peer-reviewArticle

beta-Thromboglobulin
Atherosclerosis
Cardiovascular Diseases
Blood Platelets
Population
2016
3 Citations

25-Hydroxyvitamin D Levels and Markers of Subclinical Myocardial Damage and Wall Stress: The Atherosclerosis Risk in Communities Study

Michos, E. D., Selvin, E., Misialek, J. R., McEvoy, J. W., Ndumele, C. E., Folsom, A. R., Ballantyne, C. M. & Lutsey, P. L. Nov 1 2016 In : Journal of the American Heart Association. 5, 11, e003575

Research output: Research - peer-reviewArticle

Troponin T
Atherosclerosis
25-hydroxyvitamin D
Brain Natriuretic Peptide
Cardiovascular Diseases
7 Citations

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

De Vries, P. S. , Chasman, D. I. , Sabater-Lleal, M. , Chen, M. H. , Huffman, J. E. , Steri, M. , Tang, W. , Teumer, A. , Marioni, R. E. , Grossmann, V. , Hottenga, J. J. , Trompet, S. , Müller-Nurasyid, M. , Zhao, J. H. , Brody, J. A. , Kleber, M. E. , Guo, X. , Wang, J. J. , Auer, P. L. , Attia, J. R. & 111 others Yanek, L. R., Ahluwalia, T. S., Lahti, J., Venturini, C., Tanaka, T., Bielak, L. F., Joshi, P. K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Rose, L. M., Oldmeadow, C., Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Gonnekewillemsen, . N. V., Rumley, A., Fiorillo, E., De Craen, A. J. M., Grotevendt, A., Scott, R., Taylor, K. D., Delgado, G. E., Yao, J., Kifley, A., Kooperberg, C., Qayyum, R., Lopez, L., Berentzen, T. L., Räikkönen, K., Massimomangino, . N. V., Bandinelli, S., Peyser, P. A., Wild, S., Trégouët, D. A., Wright, A. F., Marten, J., Zemunik, T., Morrison, A. C., Sennblad, B., Tofler, G., De Maat, M. P. M., De Geus, E. J. C., Lowe, G. D., Zoledziewska, M., Sattar, N., Binder, H., Völker, U., Waldenberger, M., Khaw, K. T., Mcknight, B., Huang, J., Jenny, N. S., Holliday, E. G., Qi, L., Mcevoy, M. G., Becker, D. M., Starr, J. M., Sarin, A. P., Hysi, P. G., Hernandez, D. G., Jhun, M. A., Campbell, H., Hamsten, A., Sarin, F., Mcardle, W. L., Eline Slagboom, P., Zeller, T., Koenig, W., Psaty, B., Haritunians, T., Liu, J., Palotie, A., Uitterlinden, A. G., Stott, D. J., Hofman, A., Franco, O. H., Polasek, O., Rudan, I., Morange, P. E., Wilson, J. F., Kardia, S. L. R., Ferrucci, L., Spector, T. D., Eriksson, J. G., Hansen, T., Deary, I. J., Becker, L. C., Scott, R. J., Mitchell, P., März, W., Wareham, N. J., Peters, A., Greinacher, A., Wild, P. S., Wouter Jukema, J., Boomsma, D. I., Hayward, C., Cucca, F., Tracy, R., Watkins, H., Reiner, A. P., Folsom, A. R., Ridker, P. M., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A. Jan 15 2016 In : Human Molecular Genetics. 25, 2, p. 358-370 13 p., ddv454

Research output: Research - peer-reviewArticle

Fibrinogen
Meta-Analysis
Genome
X Chromosome
Genome-Wide Association Study

Association of single nucleotide polymorphisms in the ST3GAL4 Gene with VWF antigen and factor VIII activity

Song, J., Xue, C., Preisser, J. S., Cramer, D. W., Houck, K. L., Liu, G., Folsom, A. R., Couper, D., Yu, F. & Dong, J. F. Sep 1 2016 In : PLoS One. 11, 9, e0160757

Research output: Research - peer-reviewArticle

factor VIII
single nucleotide polymorphism
antigens
genes
Factor VIII
2 Citations

Association of sleep apnea and sleep duration with peripheral artery disease: The Multi-Ethnic Study of Atherosclerosis (MESA)

Nagayoshi, M., Lutsey, P. L., Benkeser, D., Wassel, C. L., Folsom, A. R., Shahar, E., Iso, H., Allison, M. A., Criqui, M. H. & Redline, S. Mar 11 2016 (Accepted/In press) In : Atherosclerosis.

Research output: Research - peer-reviewArticle

Peripheral Arterial Disease
Sleep Apnea Syndromes
Atherosclerosis
Sleep
Ankle Brachial Index
3 Citations
von Willebrand Diseases
Carotid Artery Diseases
von Willebrand Factor
Atherosclerosis
Cardiovascular Diseases
6 Citations

Association of weight and body composition on cardiac structure and function in the ARIC study (Atherosclerosis Risk in Communities)

Bello, N. A., Cheng, S., Claggett, B., Shah, A. M., Ndumele, C. E., Roca, G. Q., Santos, A. B. S., Gupta, D., Vardeny, O., Aguilar, D., Folsom, A. R., Butler, K. R., Kitzman, D. W., Coresh, J. & Solomon, S. D. Aug 1 2016 In : Circulation: Heart Failure. 9, 8, e002978

Research output: Research - peer-reviewArticle

Body Composition
Atherosclerosis
Weights and Measures
Waist Circumference
Adipose Tissue
1 Citations

Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study

Agarwala, A., Virani, S., Couper, D., Chambless, L., Boerwinkle, E., Astor, B. C., Hoogeveen, R. C., Coresh, J., Sharrett, A. R., Folsom, A. R., Mosley, T., Ballantyne, C. M. & Nambi, V. Oct 1 2016 In : Atherosclerosis. 253, p. 156-163 8 p.

Research output: Research - peer-reviewArticle

Primary Prevention
Atherosclerosis
Cardiovascular Diseases
Biomarkers
Coronary Disease
7 Citations

Body size measures, hemostatic and inflammatory markers and risk of venous thrombosis: The Longitudinal Investigation of Thromboembolism Etiology

Cushman, M., O'Meara, E. S., Heckbert, S. R., Zakai, N. A., Rosamond, W. & Folsom, A. R. Aug 1 2016 In : Thrombosis Research. 144, p. 127-132 6 p.

Research output: Research - peer-reviewArticle

Body Weights and Measures
Thromboembolism
Body Size
Hemostatics
Venous Thrombosis
5 Citations

Cardiac structure and function and leisure-time physical activity in the elderly: The Atherosclerosis Risk in Communities Study

Hegde, S. M., Gonçalves, A., Claggett, B., Evenson, K. R., Cheng, S., Shah, A. M., Folsom, A. R. & Solomon, S. D. Aug 21 2016 In : European Heart Journal. 37, 32, p. 2544-2551 8 p.

Research output: Research - peer-reviewArticle

Leisure Activities
Atherosclerosis
Exercise
Cross-Sectional Studies
Left Ventricular Function
19 Citations

Cardiovascular risk factor targets and cardiovascular disease event risk in diabetes: A pooling project of the atherosclerosis risk in communities study, multi-ethnic study of atherosclerosis, and jackson heart study

Wong, N. D., Zhao, Y., Patel, R., Patao, C., Malik, S., Bertoni, A. G., Correa, A., Folsom, A. R., Kachroo, S., Mukherjee, J., Taylor, H. & Selvin, E. May 1 2016 In : Diabetes Care. 39, 5, p. 668-676 9 p.

Research output: Research - peer-reviewArticle

Atherosclerosis
Cardiovascular Diseases
Blood Pressure
LDL Cholesterol
Coronary Disease
4 Citations

Carotid Atherosclerosis and Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities Study

Bekwelem, W., Jensen, P. N., Norby, F. L., Soliman, E. Z., Agarwal, S. K., Lip, G. Y. H., Pan, W., Folsom, A. R., Longstreth, W. T., Alonso, A., Heckbert, S. R. & Chen, L. Y. Jun 1 2016 In : Stroke. 47, 6, p. 1643-1646 4 p.

Research output: Research - peer-reviewArticle

Carotid Artery Diseases
Atrial Fibrillation
Atherosclerosis
Stroke
Carotid Intima-Media Thickness
7 Citations

Carotid Intima-Media Thickness and Arterial Stiffness and the Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study, Multi-Ethnic Study of Atherosclerosis (MESA), and the Rotterdam Study

Chen, L. Y., Leening, M. J. G., Norby, F. L., Roetker, N. S., Hofman, A., Franco, O. H., Pan, W., Polak, J. F., Witteman, J. C. M., Kronmal, R. A., Folsom, A. R., Nazarian, S., Stricker, B. H., Heckbert, S. R. & Alonso, A. May 20 2016 In : Journal of the American Heart Association. 5, 5

Research output: Research - peer-reviewArticle

Carotid Intima-Media Thickness
Vascular Stiffness
Atrial Fibrillation
Atherosclerosis
Epidemiology
1 Citations

Circulating beta-2 microglobulin and risk of cancer: The atherosclerosis risk in communities study (ARIC)

Prizment, A. E., Linabery, A. M., Lutsey, P. L., Selvin, E., Nelson, H. H., Folsom, A. R., Church, T. R., Drake, C. G., Platz, E. A. & Joshu, C. Apr 1 2016 In : Cancer Epidemiology Biomarkers and Prevention. 25, 4, p. 657-664 8 p.

Research output: Research - peer-reviewArticle

beta 2-Microglobulin
Atherosclerosis
Neoplasms
Serum
Colorectal Neoplasms

Circulating biomarkers and abdominal aortic aneurysm incidence: The Atherosclerosis Risk in Communities (ARIC) study

Folsom, A. R., Yao, L. & Alonso, A. Mar 1 2016 In : Journal of Vascular Surgery. 63, 3, p. 846 1 p.

Research output: Research - peer-reviewArticle

Abdominal Aortic Aneurysm
Atherosclerosis
Biomarkers
Incidence
12 Citations

Development and Validation of a Sudden Cardiac Death Prediction Model for the General Population

Deo, R., Norby, F. L., Katz, R., Sotoodehnia, N., Adabag, S., Defilippi, C. R., Kestenbaum, B., Chen, L. Y., Heckbert, S. R., Folsom, A. R., Kronmal, R. A., Konety, S., Patton, K. K., Siscovick, D., Shlipak, M. G. & Alonso, A. Sep 13 2016 In : Circulation. 134, 11, p. 806-816 11 p.

Research output: Research - peer-reviewArticle

Sudden Cardiac Death
Population
Health
Cardiovascular Diseases
Blood Pressure
6 Citations

Development and validation of risk prediction models for cardiovascular events in black adults: The Jackson heart study cohort

Fox, E. R., Samdarshi, T. E., Musani, S. K., Pencina, M. J., Sung, J. H., Bertoni, A. G., Xanthakis, V., Balfour, P. C., Shreenivas, S. S., Covington, C., Liebson, P. R., Sarpong, D. F., Butler, K. R., Mosley, T. H., Rosamond, W. D., Folsom, A. R., Herrington, D. M., Vasan, R. S. & Taylor, H. A. Apr 1 2016 In : JAMA Cardiology. 1, 1, p. 15-25 11 p.

Research output: Research - peer-reviewArticle

Cardiovascular Models
Cohort Studies
Cardiovascular Diseases
Atherosclerosis
American Heart Association