Find Research Outputs

Search concepts
Selected Filters
2017

ABO blood group is associated with peripheral arterial disease in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA)

Pike, M. M., Larson, N. B., Wassel, C. L., Cohoon, K. P., Tsai, M. Y., Pankow, J. S., Hanson, N. Q., Decker, P. A., Berardi, C., Alexander, K. S., Cushman, M., Zakai, N. A. & Bielinski, S. J. May 1 2017 In : Thrombosis Research. 153, p. 1-6 6 p.

Research output: Research - peer-reviewArticle

Peripheral Arterial Disease
Blood Group Antigens
African Americans
Atherosclerosis
Ankle Brachial Index
Carotid Artery Diseases
Apolipoproteins B
LDL Lipoproteins
Lipoproteins
Atherosclerosis
3 Citations

Association of air pollution exposures with high-density lipoprotein cholesterol and particle number: The multi-ethnic study of atherosclerosis

Bell, G., Mora, S., Greenland, P., Tsai, M., Gill, E. & Kaufman, J. D. May 1 2017 In : Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 5, p. 976-982 7 p.

Research output: Research - peer-reviewArticle

Air Pollution
HDL Lipoproteins
HDL Cholesterol
Atherosclerosis
Confidence Intervals
1 Citations

Cholesterol, lipoproteins and subclinical interstitial lung disease: The MESA study

Podolanczuk, A. J., Raghu, G., Tsai, M. Y., Kawut, S. M., Peterson, E., Sonti, R., Rabinowitz, D., Johnson, C., Barr, R. G., Stukovsky, K. H., Hoffman, E. A., Carr, J. J., Ahmed, F. S., Jacobs, D. R., Watson, K., Shea, S. J. & Lederer, D. J. Jan 27 2017 (Accepted/In press) In : Thorax.

Research output: Research - peer-reviewArticle

Interstitial Lung Diseases
Matrix Metalloproteinases
HDL Cholesterol
lipoprotein cholesterol
Lung Injury

Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations

Hu, Y. , Tanaka, T. , Zhu, J. , Guan, W. , Wu, J. H. Y. , Psaty, B. M. , McKnight, B. , King, I. B. , Sun, Q. , Richard, M. , Manichaikul, A. , Frazier-Wood, A. C. , Kabagambe, E. K. , Hopkins, P. N. , Ordovas, J. M. , Ferrucci, L. , Bandinelli, S. , Arnett, D. K. , Chen, Y. D. I. , Liang, S. & 13 others Siscovick, D. S., Tsai, M. Y., Rich, S. S., Fornage, M., Hu, F. B., Rimm, E. B., Jensen, M. K., Lemaitre, R. N., Mozaffarian, D., Steffen, L. M., Morris, A. P., Li, H. & Lin, X. May 1 2017 In : Journal of Lipid Research. 58, 5, p. 974-981 8 p.

Research output: Research - peer-reviewArticle

Meta-Analysis
Population
Genes
Genome-Wide Association Study
Association reactions
1 Citations

Elevated Levels of Adhesion Proteins Are Associated with Low Ankle-Brachial Index: Multi-Ethnic Study of Atherosclerosis

Berardi, C., Wassel, C. L., Decker, P. A., Larson, N. B., Kirsch, P. S., Andrade, M. D., Tsai, M. Y., Pankow, J. S., Sale, M. M., Sicotte, H., Tang, W., Hanson, N. Q., McDermott, M. M., Criqui, M. H., Allison, M. A. & Bielinski, S. J. Apr 1 2017 In : Angiology. 68, 4, p. 322-329 8 p.

Research output: Research - peer-reviewArticle

Ankle Brachial Index
Atherosclerosis
Proteins
Peripheral Arterial Disease
Inflammation
Aortic Diseases
Lipoprotein(a)
Aortic Valve
Immunoassay
Coronary Disease
Open Access

Genetic associations with lipoprotein subfraction measures differ by ethnicity in the multi-ethnic study of atherosclerosis (MESA)

Wang, Z., Manichukal, A., Goff, D. C., Mora, S., Ordovas, J. M., Pajewski, N. M., Post, W. S., Rotter, J. I., Sale, M. M., Santorico, S. A., Siscovick, D., Tsai, M. Y., Arnett, D. K., Rich, S. & Frazier-Wood, A. C. Jun 1 2017 In : Human Genetics. 136, 6, p. 715-726 12 p.

Research output: Research - peer-reviewArticle

Lipoproteins
Atherosclerosis
Hispanic Americans
Genome
African Americans

Hepatocyte growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease

Bielinski, S. J., Berardi, C., Decker, P. A., Larson, N. B., Bell, E. J., Pankow, J. S., Sale, M. M., Tang, W., Hanson, N. Q., Wassel, C. L., De Andrade, M., Budoff, M. J., Polak, J. F., Sicotte, H. & Tsai, M. Y. Aug 1 2017 In : Heart. 103, 15, p. 1185-1193 9 p.

Research output: Research - peer-reviewArticle

Hepatocyte Growth Factor
Coronary Disease
Biomarkers
Hispanic Americans
African Americans

Long chain n-3 polyunsaturated fatty acids are not associated with circulating T-helper type 1 cells: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)

Sagawa, N., Olson, N. C., Ahuja, V., Vishnu, A., Doyle, M. F., Psaty, B. M., Jenny, N. S., Siscovick, D. S., Lemaitre, R. N., Steffen, L. M., Tsai, M. Y. & Sekikawa, A. Oct 1 2017 In : Prostaglandins Leukotrienes and Essential Fatty Acids. 125, p. 37-42 6 p.

Research output: Research - peer-reviewArticle

Th1 Cells
Omega-3 Fatty Acids
Atherosclerosis
Association reactions
Plasmas

Low high-density lipoprotein cholesterol and particle concentrations are associated with greater levels of endothelial activation markers in Multi-Ethnic Study of Atherosclerosis participants

Steffen, B. T., Bielinski, S. J., Decker, P. A., Berardi, C., Larson, N. B., Pankow, J. S., Michos, E. D., Hanson, N. Q., Herrington, D. M. & Tsai, M. Y. 2017 (Accepted/In press) In : Journal of Clinical Lipidology.

Research output: Research - peer-reviewArticle

HDL Lipoproteins
LDL Cholesterol
HDL Cholesterol
Atherosclerosis
Selectins
3 Citations

Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies

Wu, J. H. Y. , Marklund, M. , Imamura, F. , Tintle, N. , Ardisson Korat, A. V. , de Goede, J. , Zhou, X. , Yang, W. S. , de Oliveira Otto, M. C. , Kröger, J. , Qureshi, W. , Virtanen, J. K. , Bassett, J. K. , Frazier-Wood, A. C. , Lankinen, M. , Murphy, R. A. , Rajaobelina, K. , Del Gobbo, L. C. , Forouhi, N. G. , Luben, R. & 39 others Khaw, K. T., Wareham, N., Kalsbeek, A., Veenstra, J., Luo, J., Hu, F. B., Lin, H. J., Siscovick, D. S., Boeing, H., Chen, T. A., Steffen, B., Steffen, L. M., Hodge, A., Eriksdottir, G., Smith, A. V., Gudnason, V., Harris, T. B., Brouwer, I. A., Berr, C., Helmer, C., Samieri, C., Laakso, M., Tsai, M. Y., Giles, G. G., Nurmi, T., Wagenknecht, L., Schulze, M. B., Lemaitre, R. N., Chien, K. L., Soedamah-Muthu, S. S., Geleijnse, J. M., Sun, Q., Harris, W. S., Lind, L., Ärnlöv, J., Riserus, U., Micha, R., Mozaffarian, D. & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE) Dec 1 2017 In : The Lancet Diabetes and Endocrinology. 5, 12, p. 965-974 10 p.

Research output: Research - peer-reviewArticle

Omega-6 Fatty Acids
Type 2 Diabetes Mellitus
Cohort Studies
Biomarkers
Prospective Studies

Plasma concentrations of lipids during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study

Bao, W., Dar, S., Zhu, Y., Wu, J., Rawal, S., Li, S., Weir, N. L., Tsai, M. Y. & Zhang, C. Jan 1 2017 (Accepted/In press) In : Journal of Diabetes.

Research output: Research - peer-reviewArticle

Gestational Diabetes
Longitudinal Studies
Lipids
Pregnancy
Triglycerides

Rare copy number variants identified in prune belly syndrome

Boghossian, N. S., Sicko, R. J., Giannakou, A., Dimopoulos, A., Caggana, M., Tsai, M. Y., Yeung, E. H., Pankratz, N., Cole, B. R., Romitti, P. A., Browne, M. L., Fan, R., Liu, A., Kay, D. M. & Mills, J. L. Jan 1 2017 (Accepted/In press) In : European Journal of Medical Genetics.

Research output: Research - peer-reviewArticle

Prune Belly Syndrome
Genes
Urinary Tract
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Cryptorchidism

Residual atherosclerotic cardiovascular disease risk in statin-treated adults: The Multi-Ethnic Study of Atherosclerosis

Wong, N. D., Zhao, Y., Quek, R. G. W., Blumenthal, R. S., Budoff, M. J., Cushman, M., Garg, P., Sandfort, V., Tsai, M. & Lopez, J. A. G. 2017 (Accepted/In press) In : Journal of Clinical Lipidology.

Research output: Research - peer-reviewArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Atherosclerosis
Cardiovascular Diseases
Therapeutics
Tunica Intima
2 Citations

Retinol-binding protein 4 and lipids prospectively measured during early to mid-pregnancy in relation to preeclampsia and preterm birth risk

Mendola, P., Ghassabian, A., Mills, J. L., Zhang, C., Tsai, M. Y., Liu, A. & Yeung, E. H. 2017 In : American Journal of Hypertension. 30, 6, p. 569-576 8 p.

Research output: Research - peer-reviewArticle

Retinol-Binding Proteins
Premature Birth
Pre-Eclampsia
Lipids
Pregnancy

The relationship of serum soluble receptor for advanced glycation end products (sRAGE) and carboxymethyl lysine (CML) to the incidence of diabetic nephropathy in persons with type 1 diabetes

Klein, R., Horak, K., Lee, K. E., Danforth, L., Cruickshanks, K. J., Tsai, M. Y., Gangnon, R. E. & Klein, B. E. K. Sep 1 2017 In : Diabetes Care. 40, 9, p. e117-e119

Research output: Research - peer-reviewLetter

Diabetic Nephropathies
Type 1 Diabetes Mellitus
Incidence
Serum
N(6)-carboxymethyllysine
2016
2 Citations

ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Bell, E. J., Decker, P. A., Pike, M., Wassel, C. L., Tsai, M. Y., Pankow, J. S., Tang, W., Hanson, N. Q., Alexander, K., Zakai, N. A., Cushman, M. & Bielinski, S. J. Aug 1 2016 In : Atherosclerosis. 251, p. 422-429 8 p.

Research output: Research - peer-reviewArticle

Blood Group Antigens
Atherosclerosis
Alleles
Selectins
von Willebrand Factor
3 Citations

Acculturation and Plasma fatty acid concentrations in Hispanic and Chinese-American adults: The Multi-Ethnic Study of Atherosclerosis

Diep, C. S., Lemaitre, R. N., Chen, T. A., Baranowski, T., Lutsey, P. L., Manichaikul, A. W., Rich, S. S., St-Jules, D. E., Steffen, B. T., Tsai, M. Y., Siscovick, D. S. & Frazier-Wood, A. C. Feb 1 2016 In : PLoS One. 11, 2, e0149267

Research output: Research - peer-reviewArticle

Hispanic Americans
Asian Americans
acculturation
atherosclerosis
fatty acids

A longitudinal study of iron status during pregnancy and the risk of gestational diabetes: findings from a prospective, multiracial cohort

Rawal, S., Hinkle, S. N., Bao, W., Zhu, Y., Grewal, J., Albert, P. S., Weir, N. L., Tsai, M. Y. & Zhang, C. Nov 10 2016 (Accepted/In press) In : Diabetologia. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Gestational Diabetes
Longitudinal Studies
Iron
Pregnancy
Ferritins
4 Citations

A prospective study of erythrocyte polyunsaturated fatty acid, weight gain, and risk of becoming overweight or obese in middle-aged and older women

Wang, L., Manson, J. A. E., Rautiainen, S., Gaziano, J. M., Buring, J. E., Tsai, M. Y. & Sesso, H. D. Mar 1 2016 In : European Journal of Nutrition. 55, 2, p. 687-697 11 p.

Research output: Research - peer-reviewArticle

Unsaturated Fatty Acids
Weight Gain
Fatty Acids
Erythrocytes
Prospective Studies
3 Citations

Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients

Perez-Martinez, P. , Alcala-Diaz, J. F. , Kabagambe, E. K. , Garcia-Rios, A. , Tsai, M. Y. , Delgado-Lista, J. , Kolovou, G. , Straka, R. J. , Gomez-Delgado, F. , Hopkins, P. N. , Marin, C. , Borecki, I. , Yubero-Serrano, E. M. , Hixson, J. E. , Camargo, A. , Province, M. A. , Lopez-Moreno, J. , Rodriguez-Cantalejo, F. , Tinahones, F. J. , Mikhailidis, D. P. & 4 others Perez-Jimenez, F., Arnett, D. K., Ordovas, J. M. & Lopez-Miranda, J. Mar 2 2016 (Accepted/In press) In : Journal of Clinical Lipidology.

Research output: Research - peer-reviewArticle

Coronary Disease
Triglycerides
Population
Fats
Hyperlipidemias

Blood group antigen loci demonstrate multivariate genetic associations with circulating cellular adhesion protein levels in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Decker, P. A., Wassel, C. L., Pankow, J. S., Tang, W., Hanson, N. Q., Tsai, M. Y. & Bielinski, S. J. Feb 16 2016 (Accepted/In press) In : Human Genetics. p. 1-9 9 p.

Research output: Research - peer-reviewArticle

Blood Group Antigens
Atherosclerosis
Proteins
Quantitative Trait Loci
Genome
4 Citations

Circulating cellular adhesion molecules and risk of diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)

Pankow, J. S., Decker, P. A., Berardi, C., Hanson, N. Q., Sale, M., Tang, W., Kanaya, A. M., Larson, N. B., Tsai, M. Y., Wassel, C. L. & Bielinski, S. J. Jul 1 2016 In : Diabetic Medicine. 33, 7, p. 985-991 7 p.

Research output: Research - peer-reviewArticle

E-Selectin
Intercellular Adhesion Molecule-1
Atherosclerosis
Vascular Cell Adhesion Molecule-1
Cadherins

Erratum: Increased levels of copeptin before clinical diagnosis of preeclampsia (Hypertension (2014) 64 (1362-1367) Doi: 10.1161/HYPERTENSIONAHA.114.03762)

Yeung, E. H., Liu, A., Mills, J. L., Zhang, C., Männistö, T., Lu, Z., Tsai, M. Y. & Mendola, P. Jul 1 2016 In : Hypertension. 68, 1, p. e4

Research output: Research - peer-reviewComment/debate

Pre-Eclampsia
Hypertension
copeptins
2 Citations

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

Zubair, N. , Graff, M. , Ambite, J. L. , Bush, W. S. , Kichaev, G. , Lu, Y. , Manichaikul, A. , Sheu, W. H. H. , Absher, D. , Assimes, T. L. , Bielinski, S. J. , Bottinger, E. P. , Buzkova, P. , Chuang, L. M. , Chung, R. H. , Cochran, B. , Dumitrescu, L. , Gottesman, O. , Haessler, J. W. , Haiman, C. & 37 others Heiss, G., Hsiung, C. A., Hung, Y. J., Hwu, C. M., Juang, J. M. J., Marchand, L. L., Lee, I. T., Lee, W. J., Lin, L. A., Lin, D., Lin, S. Y., Mackey, R. H., Martin, L. W., Pasaniuc, B., Peters, U., Predazzi, I., Quertermous, T., Reiner, A. P., Robinson, J., Rotter, J. I., Ryckman, K. K., Schreiner, P. J., Stahl, E., Tao, R., Tsai, M. Y., Waite, L. L., Wang, T. D., Buyske, S., Chen, Y. D. I., Cheng, I., Crawford, D. C., Loos, R. J. F., Rich, S. S., Fornage, M., North, K. E., Kooperberg, C. & Carty, C. L. 2016 In : Human Molecular Genetics. 25, 24, p. 5500-5512 13 p.

Research output: Research - peer-reviewArticle

Lipids
Population
Hispanic Americans
African Americans
Asian Americans
1 Citations

Hepatocyte growth factor is positively associated with risk of stroke: The MESA (Multi-Ethnic Study of Atherosclerosis)

Bell, E. J., Larson, N. B., Decker, P. A., Pankow, J. S., Tsai, M. Y., Hanson, N. Q., Wassel, C. L., Longstreth, W. T. & Bielinski, S. J. Nov 1 2016 In : Stroke. 47, 11, p. 2689-2694 6 p.

Research output: Research - peer-reviewArticle

Hepatocyte Growth Factor
Atherosclerosis
Stroke
Confidence Intervals
Confounding Factors (Epidemiology)
4 Citations

Impact of adiposity on cellular adhesion: The Multi-Ethnic Study of atherosclerosis (MESA)

Christoph, M. J., Allison, M. A., Pankow, J. S., Decker, P. A., Kirsch, P. S., Tsai, M. Y., Sale, M. M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Berardi, C., Wassel, C. L., Larson, N. B. & Bielinski, S. J. Jan 1 2016 In : Obesity. 24, 1, p. 223-230 8 p.

Research output: Research - peer-reviewArticle

Adiposity
Atherosclerosis
Intra-Abdominal Fat
Waist-Hip Ratio
Selectins
5 Citations

Insulin-like growth factor axis and gestational diabetes mellitus: A longitudinal study in a multiracial cohort

Zhu, Y., Mendola, P., Albert, P. S., Bao, W., Hinkle, S. N., Tsai, M. Y. & Zhang, C. Nov 1 2016 In : Diabetes. 65, 11, p. 3495-3504 10 p.

Research output: Research - peer-reviewArticle

Gestational Diabetes
Somatomedins
Longitudinal Studies
Insulin-Like Growth Factor I
Insulin-Like Growth Factor Binding Protein 3
7 Citations

Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: A meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

Ma, Y. , Follis, J. L. , Smith, C. E. , Tanaka, T. , Manichaikul, A. W. , Chu, A. Y. , Samieri, C. , Zhou, X. , Guan, W. , Wang, L. , Biggs, M. L. , Chen, Y. D. I. , Hernandez, D. G. , Borecki, I. , Chasman, D. I. , Rich, S. S. , Ferrucci, L. , Irvin, M. R. , Aslibekyan, S. , Zhi, D. & 27 others Tiwari, H. K., Claas, S. A., Sha, J., Kabagambe, E. K., Lai, C. Q., Parnell, L. D., Lee, Y. C., Amouyel, P., Lambert, J. C., Psaty, B. M., King, I. B., Mozaffarian, D., McKnight, B., Bandinelli, S., Tsai, M. Y., Ridker, P. M., Ding, J., Mstat, K. L., Liu, Y., Sotoodehnia, N., Barberger-Gateau, P., Steffen, L. M., Siscovick, D. S., Absher, D., Arnett, D. K., Ordovás, J. M. & Lemaitre, R. N. Feb 1 2016 In : American Journal of Clinical Nutrition. 103, 2, p. 567-578 12 p.

Research output: Research - peer-reviewArticle

Lipid A
Methylation
Meta-Analysis
Epidemiology
Cohort Studies
5 Citations

Lipids, obesity and gallbladder disease in women: Insights from genetic studies using the cardiovascular gene-centric 50K SNP array

Rodriguez, S. , Gaunt, T. R. , Guo, Y. , Zheng, J. , Barnes, M. R. , Tang, W. , Danish, F. , Johnson, A. , Castillo, B. A. , Li, Y. R. , Hakonarson, H. , Buxbaum, S. G. , Palmer, T. , Tsai, M. Y. , Lange, L. A. , Ebrahim, S. , Smith, G. D. , Lawlor, D. A. , Folsom, A. R. , Hoogeveen, R. & 3 others Reiner, A., Keating, B. & Day, I. N. M. Jan 1 2016 In : European Journal of Human Genetics. 24, 1, p. 106-112 7 p.

Research output: Research - peer-reviewArticle

Gallbladder Diseases
Single Nucleotide Polymorphism
Obesity
Lipids
Genes
6 Citations

Lipoprotein(a) Levels Are Associated With Subclinical Calcific Aortic Valve Disease in White and Black Individuals: The Multi-Ethnic Study of Atherosclerosis

Cao, J., Steffen, B. T., Budoff, M., Post, W. S., Thanassoulis, G., Kestenbaum, B., McConnell, J. P., Warnick, R., Guan, W. & Tsai, M. Y. Mar 3 2016 (Accepted/In press) In : Arteriosclerosis, Thrombosis, and Vascular Biology.

Research output: Research - peer-reviewArticle

Aortic Diseases
Lipoprotein(a)
Aortic Valve
Atherosclerosis
hydroquinone

Meta-analysis of genome-wide association studies identifies three novel loci for saturated fatty acids in East Asians

Zhu, J., Manichaikul, A., Hu, Y., Chen, Y. D. I., Liang, S., Steffen, L. M., Rich, S. S., Tsai, M., Siscovick, D. S., Lemaitre, R. N., Li, H. & Lin, X. Mar 1 2016 (Accepted/In press) In : European Journal of Nutrition. p. 1-8 8 p.

Research output: Research - peer-reviewArticle

AMP Deaminase
Genome-Wide Association Study
Meta-Analysis
Fatty Acids
Population
6 Citations

Rare copy number variants implicated in posterior urethral valves

Boghossian, N. S., Sicko, R. J., Kay, D. M., Rigler, S. L., Caggana, M., Tsai, M. Y., Yeung, E. H., Pankratz, N., Cole, B. R., Druschel, C. M., Romitti, P. A., Browne, M. L., Fan, R., Liu, A., Brody, L. C. & Mills, J. L. Mar 1 2016 In : American Journal of Medical Genetics, Part A. 170, 3, p. 622-633 12 p.

Research output: Research - peer-reviewArticle

Chromosomes
Gene Dosage
Population Control
Essential Genes
Live Birth
8 Citations

Sex and ethnic differences in the associations between lipoprotein(a) and peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis

Forbang, N. I., Criqui, M. H., Allison, M. A., Ix, J. H., Steffen, B. T., Cushman, M. & Tsai, M. Y. Feb 1 2016 In : Journal of Vascular Surgery. 63, 2, p. 453-458 6 p.

Research output: Research - peer-reviewArticle

Lipoprotein(a)
Peripheral Arterial Disease
Sex Characteristics
Atherosclerosis
African Americans

Vascular biomarkers to predict response to exercise in Alzheimer's disease: The study protocol

Li, D., Thomas, R., Tsai, M. Y., Li, L., Vock, D. M., Greimel, S. & Yu, F. Dec 1 2016 In : BMJ Open. 6, 12, e011054

Research output: Research - peer-reviewArticle

Cognition
Blood Vessels
Alzheimer Disease
Biomarkers
Exercise
33 Citations

ω-3 Polyunsaturated fatty acid biomarkers and coronary heart disease: Pooling project of 19 cohort studies

Del Gobbo, L. C. , Imamura, F. , Aslibekyan, S. , Marklund, M. , Virtanen, J. K. , Wennberg, M. , Yakoob, M. Y. , Chiuve, S. E. , Dela Cruz, L. , Frazier-Wood, A. C. , Fretts, A. M. , Guallar, E. , Matsumoto, C. , Prem, K. , Tanaka, T. , Wu, J. H. Y. , Zhou, X. , Helmer, C. , Ingelsson, E. , Yuan, J. M. & 30 others Barberger-Gateau, P., Campos, H., Chaves, P. H. M., Djoussé, L., Giles, G. G., Gómez-Aracena, J., Hodge, A. M., Hu, F. B., Jansson, J. H., Johansson, I., Khaw, K. T., Koh, W. P., Lemaitre, R. N., Lind, L., Luben, R. N., Rimm, E. B., Risérus, U., Samieri, C., Franks, P. W., Siscovick, D. S., Stampfer, M., Steffen, L. M., Steffen, B. T., Tsai, M. Y., Van Dam, R. M., Voutilainen, S., Willett, W. C., Woodward, M., Mozaffarian, D. & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe) Aug 1 2016 In : JAMA Internal Medicine. 176, 8, p. 1155-1166 12 p.

Research output: Research - peer-reviewArticle

Omega-3 Fatty Acids
Unsaturated Fatty Acids
Coronary Disease
Cohort Studies
Biomarkers
2015
2 Citations
Arachidonate 5-Lipoxygenase
Coronary Disease
Atherosclerosis
Cohort Studies
Genes
1 Citations

A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet Network

Hidalgo, B., Aslibekyan, S., Wiener, H. W., Irvin, M. R., Straka, R. J., Borecki, I. B., Tiwari, H. K., Tsai, M. Y., Hopkins, P. N., Ordovas, J. M. & Arnett, D. K. Sep 23 2015 In : Pharmacogenetics and Genomics. 25, 10, p. 511-514 4 p.

Research output: Research - peer-reviewArticle

Fenofibrate
LDL Cholesterol
Diet
Lipids
Pharmaceutical Preparations
14 Citations

Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium

Smith, C. E. , Follis, J. L. , Nettleton, J. A. , Foy, M. , Wu, J. H. Y. , Ma, Y. , Tanaka, T. , Manichakul, A. W. , Wu, H. , Chu, A. Y. , Steffen, L. M. , Fornage, M. , Mozaffarian, D. , Kabagambe, E. K. , Ferruci, L. , Chen, Y. D. I. , Rich, S. S. , Djoussé, L. , Ridker, P. M. , Tang, W. & 16 others Mcknight, B., Tsai, M. Y., Bandinelli, S., Rotter, J. I., Hu, F. B., Chasman, D. I., Psaty, B. M., Arnett, D. K., King, I. B., Sun, Q., Wang, L., Lumley, T., Chiuve, S. E., Siscovick, D. S., Ordovás, J. M. & Lemaitre, R. N. Jul 1 2015 In : Molecular Nutrition and Food Research. 59, 7, p. 1373-1383 11 p.

Research output: Research - peer-reviewArticle

meta-analysis
dietary fat
erythrocytes
fatty acids
Erythrocyte Membrane
33 Citations

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

Aslibekyan, S. , Demerath, E. W. , Mendelson, M. , Zhi, D. , Guan, W. , Liang, L. , Sha, J. , Pankow, J. S. , Liu, C. , Irvin, M. R. , Fornage, M. , Hidalgo, B. , Lin, L. A. , Stanton Thibeault, K. , Bressler, J. , Tsai, M. Y. , Grove, M. L. , Hopkins, P. N. , Boerwinkle, E. , Borecki, I. B. & 5 others Ordovas, J. M., Levy, D., Tiwari, H. K., Absher, D. M. & Arnett, D. K. Jul 1 2015 In : Obesity. 23, 7, p. 1493-1501 9 p.

Research output: Research - peer-reviewArticle

Waist Circumference
Methylation
Body Mass Index
Cytosine
Guanine
8 Citations

Genetic loci associated with circulating levels of very long-chain saturated fatty acids

Lemaitre, R. N. , King, I. B. , Kabagambe, E. K. , Wu, J. H. Y. , McKnight, B. , Manichaikul, A. , Guan, W. , Sun, Q. , Chasman, D. I. , Foy, M. , Wang, L. , Zhu, J. , Siscovick, D. S. , Tsai, M. Y. , Arnett, D. K. , Psaty, B. M. , Djousse, L. , Chen, Y. D. I. , Tang, W. , Weng, L. C. & 12 others Wu, H., Jensen, M. K., Chu, A. Y., Jacobs, D. R., Rich, S. S., Mozaffarian, D., Steffen, L., Rimm, E. B., Hu, F. B., Ridker, P. M., Fornage, M. & Friedlander, Y. Jan 1 2015 In : Journal of Lipid Research. 56, 1, p. 176-184 9 p.

Research output: Research - peer-reviewArticle

Genetic Loci
Fatty Acids
Genes
Association reactions
Sphingolipids
9 Citations

Genetic loci associated with circulating phospholipid trans fatty acids: A meta-analysis of genome-wide association studies from the CHARGE consortium

Mozaffarian, D. , Kabagambe, E. K. , Johnson, C. O. , Lemaitre, R. N. , Manichaikul, A. , Sun, Q. , Foy, M. , Wang, L. , Wiener, H. , Irvin, M. R. , Rich, S. S. , Wu, H. , Jensen, M. K. , Chasman, D. I. , Chu, A. Y. , Fornage, M. , Steffen, L. , King, I. B. , McKnight, B. , Psaty, B. M. & 9 others Djoussé, L., Chen, I. Y. D., Wu, J. H. Y., Siscovick, D. S., Ridker, P. M., Tsai, M. Y., Rimm, E. B., Hu, F. B. & Arnett, D. K. Feb 1 2015 In : American Journal of Clinical Nutrition. 101, 2, p. 398-406 9 p.

Research output: Research - peer-reviewArticle

Trans Fatty Acids
Genetic Loci
Genome-Wide Association Study
Meta-Analysis
Phospholipids
15 Citations

Genetic variants associated with quantitative glucose homeostasis traits translate to type 2 diabetes in Mexican Americans: The GUARDIAN (Genetics underlying diabetes in Hispanics) consortium

Palmer, N. D. , Goodarzi, M. O. , Langefeld, C. D. , Wang, N. , Guo, X. , Taylor, K. D. , Fingerlin, T. E. , Norris, J. M. , Buchanan, T. A. , Xiang, A. H. , Haritunians, T. , Ziegler, J. T. , Williams, A. H. , Stefanovski, D. , Cui, J. , Mackay, A. W. , Henkin, L. F. , Bergman, R. N. , Gao, X. , Gauderman, J. & 29 others Varma, R., Hanis, C. L., Cox, N. J., Highland, H. M., Below, J. E., Williams, A. L., Burtt, N. P., Aguilar-Salinas, C. A., Huerta-Chagoya, A., Gonzalez-Villalpando, C., Orozco, L., Haiman, C. A., Tsai, M. Y., Johnson, W. C., Yao, J., Rasmussen-Torvik, L., Pankow, J., Snively, B., Jackson, R. D., Liu, S., Nadler, J. L., Kandeel, F., Chen, Y. D. I., Bowden, D. W., Rich, S. S., Raffel, L. J., Rotter, J. I., Watanabe, R. M. & Wagenknecht, L. E. May 1 2015 In : Diabetes. 64, 5, p. 1853-1866 14 p.

Research output: Research - peer-reviewArticle

Hispanic Americans
Type 2 Diabetes Mellitus
Homeostasis
Glucose
Insulin
11 Citations

Genetic variants modify the effect of age on APOE methylation in the genetics of lipid lowering drugs and diet network study

Ma, Y., Smith, C. E., Lai, C. Q., Irvin, M. R., Parnell, L. D., Lee, Y. C., Pham, L., Aslibekyan, S., Claas, S. A., Tsai, M. Y., Borecki, I. B., Kabagambe, E. K., Berciano, S., Ordovás, J. M., Absher, D. M. & Arnett, D. K. Feb 1 2015 In : Aging Cell. 14, 1, p. 49-59 11 p.

Research output: Research - peer-reviewArticle

Apolipoproteins E
Methylation
Diet
Lipids
Pharmaceutical Preparations
7 Citations

Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in chinese and european-ancestry populations

Hu, Y., Li, H., Lu, L., Manichaikul, A., Zhu, J., Chen, I. Y. D., Sun, L., Liang, S., Siscovick, D. S., Steffen, L. M., Tsai, M. Y., Rich, S. S., Lemaitre, R. N. & Lin, X. Aug 17 2015 In : Human Molecular Genetics. 25, 6, p. 1215-1224 10 p., ddw002

Research output: Research - peer-reviewArticle

Genome-Wide Association Study
Unsaturated Fatty Acids
Meta-Analysis
Genome
Population
180 Citations

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials

Swerdlow, D. I. , Preiss, D. , Kuchenbaecker, K. B. , Holmes, M. V. , Engmann, J. E. L. , Shah, T. , Sofat, R. , Stender, S. , Johnson, P. C. D. , Scott, R. A. , Leusink, M. , Verweij, N. , Sharp, S. J. , Guo, Y. , Giambartolomei, C. , Chung, C. , Peasey, A. , Amuzu, A. , Li, K. , Palmen, J. & 113 others Howard, P., Cooper, J. A., Drenos, F., Li, Y. R., Lowe, G., Gallacher, J., Stewart, M. C. W., Tzoulaki, I., Buxbaum, S. G., Van Der A, D. L., Forouhi, N. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Schnabel, R. B., Hubacek, J. A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S., Baldassarre, D., Sennblad, B., Tremoli, E., De Faire, U., Veglia, F., Ford, I., Jukema, J. W., Westendorp, R. G. J., De Borst, G. J., De Jong, P. A., Algra, A., Spiering, W., Der Zee, A. H. M. V., Klungel, O. H., De Boer, A., Doevendans, P. A., Eaton, C. B., Robinson, J. G., Duggan, D., Kjekshus, J., Downs, J. R., Gotto, A. M., Keech, A. C., Marchioli, R., Tognoni, G., Sever, P. S., Poulter, N. R., Waters, D. D., Pedersen, T. R., Amarenco, P., Nakamura, H., McMurray, J. J. V., Lewsey, J. D., Chasman, D. I., Ridker, P. M., Maggioni, A. P., Tavazzi, L., Ray, K. K., Seshasai, S. R. K., Manson, J. E., Price, J. F., Whincup, P. H., Morris, R. W., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Schreiner, P. J., Fornage, M., Siscovick, D. S., Cushman, M., Kumari, M., Wareham, N. J., Verschuren, W. M. M., Redline, S., Patel, S. R., Whittaker, J. C., Hamsten, A., Delaney, J. A., Dale, C., Gaunt, T. R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B. A., Van Der Harst, P., Brunner, E. J., Tybjaerg-Hansen, A., Marmot, M. G., Krauss, R. M., Tsai, M., Coresh, J., Hoogeveen, R. C., Psaty, B. M., Lange, L. A., Hakonarson, H., Dudbridge, F., Humphries, S. E., Talmud, P. J., Kivimäki, M., Timpson, N. J., Langenberg, C., Asselbergs, F. W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J. G., Reiner, A. P., Keating, B. J., Hingorani, A. D. & Sattar, N. Jan 24 2015 In : The Lancet. 385, 9965, p. 351-361 11 p.

Research output: Research - peer-reviewArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coenzyme A
Type 2 Diabetes Mellitus
Oxidoreductases
Alleles
98 Citations

Mendelian randomization of blood lipids for coronary heart disease

Holmes, M. V. , Asselbergs, F. W. , Palmer, T. M. , Drenos, F. , Lanktree, M. B. , Nelson, C. P. , Dale, C. E. , Padmanabhan, S. , Finan, C. , Swerdlow, D. I. , Tragante, V. , Van Iperen, E. P. A. , Sivapalaratnam, S. , Shah, S. , Elbers, C. C. , Shah, T. , Engmann, J. , Giambartolomei, C. , White, J. , Zabaneh, D. & 48 others Sofat, R., McLachlan, S., Doevendans, P. A., Balmforth, A. J., Hall, A. S., North, K. E., Almoguera, B., Hoogeveen, R. C., Cushman, M., Fornage, M., Patel, S. R., Redline, S., Siscovick, D. S., Tsai, M. Y., Karczewski, K. J., Hofker, M. H., Verschuren, W. M., Bots, M. L., Van Der Schouw, Y. T., Melander, O., Dominiczak, A. F., Morris, R., Ben-Shlomo, Y., Price, J., Kumari, M., Baumert, J., Peters, A., Thorand, B., Koenig, W., Gaunt, T. R., Humphries, S. E., Clarke, R., Watkins, H., Farrall, M., Wilson, J. G., Rich, S. S., De Bakker, P. I. W., Lange, L. A., Smith, G. D., Reiner, A. P., Talmud, P. J., Kivimäki, M., Lawlor, D. A., Dudbridge, F., Samani, N. J., Keating, B. J., Hingorani, A. D. & Casas, J. P. Mar 1 2015 In : European Heart Journal. 36, 9, p. 539-550 12 p.

Research output: Research - peer-reviewArticle

Random Allocation
Single Nucleotide Polymorphism
Coronary Disease
Lipids
HDL Cholesterol
6 Citations

Multi-ethnic analysis reveals soluble l-selectin may be post-transcriptionally regulated by 3′UTR polymorphism: the Multi-Ethnic Study of Atherosclerosis (MESA)

Berardi, C., Larson, N. B., Decker, P. A., Wassel, C. L., Kirsch, P. S., Pankow, J. S., Sale, M. M., de Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Tsai, M. Y., Chen, Y. D. I. & Bielinski, S. J. 2015 In : Human Genetics. 134, 4, p. 393-403 11 p.

Research output: Research - peer-reviewArticle

Selectins
3' Untranslated Regions
Atherosclerosis
Linear Models
Cardiovascular Diseases