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2018

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism

Rousseaux, M. W. C. , Tschumperlin, T. , Lu, H. C. , Lackey, E. P. , Bondar, V. V. , Wan, Y. W. , Tan, Q. , Adamski, C. J. , Friedrich, J. , Twaroski, K. , Chen, W. , Tolar, J. , Henzler, C. , Sharma, A. , Bajić, A. , Lin, T. , Duvick, L. , Liu, Z. , Sillitoe, R. V. , Zoghbi, H. Y. & 1 others Orr, H. T. Jan 1 2018 (Accepted/In press) In : Neuron.

Research output: Contribution to journalArticle

Spinocerebellar Ataxias
Ataxia
Cerebellum
Pathology
Neurons

Crispr/cas9-based cellular engineering for targeted gene overexpression

Osborn, M. J., Lees, C. J., McElroy, A. N., Merkel, S. C., Eide, C. R., Mathews, W., Feser, C. J., Tschann, M., McElmury, R. T., Webber, B. R., Kim, C. J., Blazar, B. R. & Tolar, J. Apr 1 2018 In : International Journal of Molecular Sciences. 19, 4, 946

Research output: Contribution to journalArticle

Cell Engineering
genes
Genes
engineering
T-cells
Stellite
gene therapy
Gene therapy
Antigen Receptors
T-cells

Inside out: Regenerative medicine for recessive dystrophic epidermolysis bullosa

Vanden Oever, M., Twaroski, K., Osborn, M. J., Wagner, J. E. & Tolar, J. Jan 1 2018 In : Pediatric Research. 83, 1-2, p. 318-324 7 p.

Research output: Contribution to journalReview article

Epidermolysis Bullosa Dystrophica
Epidermolysis Bullosa
Regenerative Medicine
Mesenchymal Stromal Cells
Induced Pluripotent Stem Cells
Adrenoleukodystrophy
Blood-Brain Barrier
Endothelial Cells
Brain
Ethylene Oxide
1 Citations

Regenerative Solutions for Inherited Diseases

Tolar, J. May 1 2018 In : Clinical pharmacology and therapeutics. 103, 5, p. 763-766 4 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Regenerative Medicine
Computational Biology
Therapeutics
Health
2017

Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: Potential for biomarker development and insight into pathogenesis

Hinderer, C., Katz, N., Louboutin, J. P., Bell, P., Tolar, J., Orchard, P. J., Lund, T. C., Nayal, M., Weng, L., Mesaros, C., de Souza, C. F. M., Corte, A. D., Giugliani, R. & Wilson, J. M. Oct 1 2017 In : Human molecular genetics. 26, 19, p. 3837-3849 13 p.

Research output: Contribution to journalArticle

Mucopolysaccharidoses
Polyamines
Spermine
Mucopolysaccharidosis I
Biomarkers
3 Citations

A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing

Astuti, Y., Kramer, A. C., Blake, A. L., Blazar, B. R., Tolar, J., Taisto, M. E. & Lund, T. C. Jan 10 2017 In : Stem Cell Reports. 8, 1, p. 177-190 14 p.

Research output: Contribution to journalArticle

Bioluminescence
Zebrafish
Ergosterol
Imaging techniques
Firefly Luciferases
1 Citations

Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology

Osborn, M. J., Webber, B. R., McElmurry, R. T., Rudser, K. D., DeFeo, A. P., Muradian, M., Petryk, A., Hallgrimsson, B., Blazar, B. R., Tolar, J. & Braunlin, E. A. Mar 1 2017 In : Journal of Inherited Metabolic Disease. 40, 2, p. 281-289 9 p.

Research output: Contribution to journalArticle

Iduronidase
Mucopolysaccharidosis I
Angiotensin Receptors
Renin-Angiotensin System
Pathology

CRISPR/Cas9-mediated correction of the FANCD1 Gene in primary patient cells

Skvarova Kramarzova, K., Osborn, M. J., Webber, B. R., Defeo, A. P., McElroy, A. N., Kim, C. J. & Tolar, J. Jun 14 2017 In : International Journal of Molecular Sciences. 18, 6, 1269

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
anemias
Fanconi Anemia
genes
Genes
6 Citations

Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation

Dietz, A. C., Mehta, P. A., Vlachos, A., Savage, S. A., Bresters, D., Tolar, J., Boulad, F., Dalle, J. H., Bonfim, C., de la Fuente, J., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P. Jan 14 2017 (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Cell Transplantation
Fanconi Anemia
Bone Marrow
Pediatrics
Transplants
1 Citations

Feeder-Free Derivation of Naive Human Pluripotent Stem Cells

Ward, E., Twaroski, K. & Tolar, J. Aug 1 2017 In : Stem Cells and Development. 26, 15, p. 1087-1089 3 p.

Research output: Contribution to journalLetter

Pluripotent Stem Cells
5 Citations

Genome-wide Specificity of Highly Efficient TALENs and CRISPR/Cas9 for T Cell Receptor Modification

Knipping, F., Osborn, M. J., Petri, K., Tolar, J., Glimm, H., von Kalle, C., Schmidt, M. & Gabriel, R. Mar 17 2017 In : Molecular Therapy - Methods and Clinical Development. 4, p. 213-224 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
T-Cell Antigen Receptor
Genome
Guide RNA
T-Lymphocytes
1 Citations

Heparin Enhances Transfection in Concert with a Trehalose-Based Polycation with Challenging Cell Types

Boyle, W. S., Senger, K., Tolar, J. & Reineke, T. M. Jan 9 2017 In : Biomacromolecules. 18, 1, p. 56-67 12 p.

Research output: Contribution to journalArticle

Trehalose
Heparin
A73025
Fibroblasts
polycations
4 Citations

Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23

Lee, J. Y. W. , Hsu, C. K. , Michael, M. , Nanda, A. , Liu, L. , McMillan, J. R. , Pourreyron, C. , Takeichi, T. , Tolar, J. , Reid, E. , Hayday, T. , Blumen, S. C. , Abu-Mouch, S. , Straussberg, R. , Basel-Vanagaite, L. , Barhum, Y. , Zouabi, Y. , Al-Ajmi, H. , Huang, H. Y. , Lin, T. C. & 6 others Akiyama, M., Lee, J. Y. Y., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A. Feb 2 2017 In : American Journal of Human Genetics. 100, 2, p. 364-370 7 p.

Research output: Contribution to journalArticle

Spastic Paraparesis
Protein-Serine-Threonine Kinases
Protein-Tyrosine Kinases
Pedigree
Keratinocytes
2 Citations

Late Effects Screening Guidelines after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement From the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects After Pediatric HCT

Dietz, A. C., Savage, S. A., Vlachos, A., Mehta, P. A., Bresters, D., Tolar, J., Bonfim, C., Dalle, J. H., de la Fuente, J., Skinner, R., Boulad, F., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P. 2017 (Accepted/In press) In : Biology of Blood and Marrow Transplantation.

Research output: Contribution to journalArticle

Cell Transplantation
Bone Marrow
Guidelines
Pediatrics
Transplants
Cell Transplantation
Prospective Studies
Transplants
Adrenoleukodystrophy
Busulfan
2 Citations

PAX7 Targets, CD54, Integrin α9β1, and SDC2, Allow Isolation of Human ESC/iPSC-Derived Myogenic Progenitors

Magli, A., Incitti, T., Kiley, J., Swanson, S. A., Darabi, R., Rinaldi, F., Selvaraj, S., Yamamoto, A., Tolar, J., Yuan, C., Stewart, R., Thomson, J. A. & Perlingeiro, R. C. R. Jun 27 2017 In : Cell Reports. 19, 13, p. 2867-2877 11 p.

Research output: Contribution to journalArticle

Stem cells
Integrins
Muscle
Pluripotent Stem Cells
Muscles

Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients

Ivaturi, V., Dvorak, C. C., Chan, D., Liu, T., Cowan, M. J., Wahlstrom, J., Stricherz, M., Jennissen, C., Orchard, P. J., Tolar, J., Pai, S. Y., Huang, L., Aweeka, F. & Long-Boyle, J. Oct 1 2017 In : Biology of Blood and Marrow Transplantation. 23, 10, p. 1701-1713 13 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Pediatrics
Transplants
Cell Transplantation
Therapeutics

Rapid DNA replication origin licensing protects stem cell pluripotency

Matson, J. P., Dumitru, R., Coryell, P., Baxley, R. M., Chen, W., Twaroski, K., Webber, B. R., Tolar, J., Bielinsky, A. K., Purvis, J. E. & Cook, J. G. Nov 17 2017 In : eLife. 6, e30473

Research output: Contribution to journalArticle

Replication Origin
Licensure
DNA Replication
Stem Cells
Maintenance
1 Citations

Rapid generation of Col7a1 mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

Webber, B. R., O'Connor, K. T., McElmurry, R. T., Durgin, E. N., Eide, C. R., Lees, C. J., Riddle, M. J., Mathews, W. E., Frank, N. Y., Kluth, M. A., Ganss, C., Moriarity, B. S., Frank, M. H., Osborn, M. J. & Tolar, J. Oct 1 2017 In : Laboratory Investigation. 97, 10, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa Dystrophica
Immunosuppressive Agents
Mesenchymal Stromal Cells
Skin
Clustered Regularly Interspaced Short Palindromic Repeats
2016
1 Citations

A novel explanation of corneal clouding in a bone marrow transplant-treated patient with Hurler syndrome

Yuan, C., Bothun, E. D., Hardten, D. R., Tolar, J. & McLoon, L. K. Jul 1 2016 In : Experimental eye research. 148, p. 83-89 7 p.

Research output: Contribution to journalArticle

Mucopolysaccharidosis I
Cornea
Bone Marrow
Transplants
Collagen
1 Citations
Metachromatic Leukodystrophy
Cytokines
Sulfoglycosphingolipids
Lysosomal Storage Diseases
Interleukin 1 Receptor Antagonist Protein
7 Citations

CRISPR/Cas9 targeted gene editing and cellular engineering in fanconi anemia

Osborn, M. J., Lonetree, C. L., Webber, B. R., Patel, D., Dunmire, S., Defeo, A. P., McElroy, A. N., Macmillan, M. L., Wagner, J. E., Blazar, B. R. & Tolar, J. Oct 15 2016 In : Stem Cells and Development. 25, 20, p. 1591-1603 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Cell Engineering
Fanconi Anemia
Induced Pluripotent Stem Cells
Genes
11 Citations

Enzyme replacement therapy prior to haematopoietic stem cell transplantation in Mucopolysaccharidosis Type I: 10 year combined experience of 2 centres

Ghosh, A., Miller, W., Orchard, P. J., Jones, S. A., Mercer, J., Church, H. J., Tylee, K., Lund, T., Bigger, B. W., Tolar, J. & Wynn, R. F. Mar 1 2016 In : Molecular Genetics and Metabolism. 117, 3, p. 373-377 5 p.

Research output: Contribution to journalArticle

Mucopolysaccharidosis I
Enzyme Replacement Therapy
Transplants
Hematopoietic Stem Cell Transplantation
Stem cells
36 Citations

Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL nucleases

Osborn, M. J. , Webber, B. R. , Knipping, F. , Lonetree, C. L. , Tennis, N. , DeFeo, A. P. , McElroy, A. N. , Starker, C. G. , Lee, C. , Merkel, S. , Lund, T. C. , Kelly-Spratt, K. S. , Jensen, M. C. , Voytas, D. F. , Von Kalle, C. , Schmidt, M. , Gabriel, R. , Hippen, K. L. , Miller, J. S. , Scharenberg, A. M. & 2 others Tolar, J. & Blazar, B. R. Mar 1 2016 In : Molecular Therapy. 24, 3, p. 570-581 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
T-Lymphocytes
T-Cell Antigen Receptor
Adoptive Immunotherapy
Neoplasm Antigens

Fast, Efficient, and Gentle Transfection of Human Adherent Cells in Suspension

Agrawal, P., Ingle, N. P., Boyle, W. S., Ward, E., Tolar, J., Dorfman, K. D. & Reineke, T. M. Apr 27 2016 In : ACS Applied Materials and Interfaces. 8, 14, p. 8870-8874 5 p.

Research output: Contribution to journalArticle

Suspensions
Genes
Cells
Gene transfer
Physiology
7 Citations

Gene editing and its application for hematological diseases

Osborn, M. J., Belanto, J. J., Tolar, J. & Voytas, D. F. Jul 1 2016 In : International Journal of Hematology. 104, 1, p. 18-28 11 p.

Research output: Contribution to journalReview article

Hematologic Diseases
Hematopoietic Stem Cells
Transcriptome
Clustered Regularly Interspaced Short Palindromic Repeats
Genome
4 Citations

Gene editing toward the use of autologous therapies in recessive dystrophic epidermolysis bullosa

Perdoni, C., Osborn, M. J. & Tolar, J. Feb 1 2016 In : Translational Research. 168, p. 50-58 9 p.

Research output: Contribution to journalReview article

Collagen Type VII
Epidermolysis Bullosa Dystrophica
Genes
Defects
Therapeutics
7 Citations

GSK3β inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells

Kitajima, K., Nakajima, M., Kanokoda, M., Kyba, M., Dandapat, A., Tolar, J., Saito, M. K., Toyoda, M., Umezawa, A. & Hara, T. Jan 1 2016 In : Experimental Hematology. 44, 1, p. 68-74.e10

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Pluripotent Stem Cells
Endothelial Cells
Cell Differentiation
Mesoderm

Hematopoietic Cell Transplantation for Fanconi Anemia

Wagner, J. E., Tolar, J., Auerbach, A. D. & MacMillan, M. L. Jan 1 2016 Thomas' Hematopoietic Cell Transplantation: Fifth Edition. Wiley Blackwell, Vol. 2-2, p. 923-946 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fanconi Anemia
Cell Transplantation
Bone Marrow
Radiation
Inborn Genetic Diseases
34 Citations
Interleukin-15
Natural Killer Cells
Antigens
Cell Degranulation
Survival

Induced pluripotency and gene editing in fanconi anemia

Navarro, S., Giorgetti, A., Raya, A. & Tolar, J. Oct 1 2016 In : Current Gene Therapy. 16, 5, p. 321-328 8 p.

Research output: Contribution to journalReview article

Fanconi Anemia
Induced Pluripotent Stem Cells
Genetic Therapy
Targeted Gene Repair
Bone Marrow Diseases
1 Citations

miR-29 Regulates Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa

Vanden Oever, M., Muldoon, D., Mathews, W., McElmurry, R. & Tolar, J. Oct 1 2016 In : Journal of Investigative Dermatology. 136, 10, p. 2013-2021 9 p.

Research output: Contribution to journalArticle

Collagen Type VII
Epidermolysis Bullosa Dystrophica
MicroRNAs
Transforming Growth Factor beta
Skin
64 Citations

Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

Wagner, J. E., Brunstein, C. G., Boitano, A. E., Defor, T. E., McKenna, D., Sumstad, D., Blazar, B. R., Tolar, J., Le, C., Jones, J., Cooke, M. P. & Bleul, C. C. Jan 7 2016 In : Cell Stem Cell. 18, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Fetal Blood
Transplants
Aryl Hydrocarbon Receptors
Hematopoietic Stem Cell Transplantation
2 Citations

Preclinical Testing of Antihuman CD28 Fab′ Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease

Hippen, K. L., Watkins, B., Tkachev, V., Lemire, A. M., Lehnen, C., Riddle, M. J., Singh, K., Panoskaltsis-Mortari, A., Vanhove, B., Tolar, J., Kean, L. S. & Blazar, B. R. Dec 1 2016 In : Transplantation. 100, 12, p. 2630-2639 10 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Primates
Rodentia
Animal Models
Antibodies
14 Citations

Rapid induction of cerebral organoids from human induced pluripotent stem cells using a chemically defined hydrogel and defined cell culture medium

Lindborg, B. A., Brekke, J. H., Vegoe, A. L., Ulrich, C. B., Haider, K. T., Subramaniam, S., Venhuizen, S. L., Eide, C. R., Orchard, P. J., Chen, W., Wang, Q., Pelaez, F., Scott, C. M., Kokkoli, E., Keirstead, S. A., Dutton, J. R., Tolar, J. & O’Brien, T. D. 2016 In : Stem cells translational medicine. 5, 7, p. 970-979 10 p.

Research output: Contribution to journalArticle

Organoids
Induced Pluripotent Stem Cells
Hydrogel
Culture Media
Cell Culture Techniques

Toxic epidermal necrolysis in recessive dystrophic epidermolysis bullosa following bone marrow transplantation

Boull, C. L., Hylwa, S. A., Sajic, D., Wagner, J. E., Tolar, J. & Hook, K. P. Jun 1 2016 In : Journal of Pediatrics. 173, p. 242-244 3 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa Dystrophica
Stevens-Johnson Syndrome
Bone Marrow Transplantation
Epidermolysis Bullosa
Re-Epithelialization

TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells

Kramer, A. C., Weber, J., Zhang, Y., Tolar, J., Gibbens, Y. Y., Shevik, M. & Lund, T. C. Mar 30 2016 (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

Erythroid Cells
Oxidative stress
Reactive Oxygen Species
Oxidative Stress
Zebrafish
1 Citations

Venturing into the New Science of Nucleases

Tolarová, M., McGrath, J. A. & Tolar, J. Jan 1 2016 In : Journal of Investigative Dermatology. 136, 4, p. 742-745 4 p.

Research output: Contribution to journalComment/debate

Epidermolysis Bullosa Dystrophica
Zinc Fingers
DNA Repair
Genes
Genome
2015
7 Citations

A biologic Velcro patch

Tolar, J. & Wagner, J. E. Jan 22 2015 In : New England Journal of Medicine. 372, 4, p. 382-384 3 p.

Research output: Contribution to journalArticle

Collagen Type VII
Epidermolysis Bullosa Dystrophica
Induced Pluripotent Stem Cells
Combined Modality Therapy
Skin Transplantation
1 Citations

A living band-aid for epidermolysis bullosa

Tolar, J. & Tolar, M. Jan 1 2015 In : Blood Transfusion. 13, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Epidermolysis Bullosa Dystrophica
Epidermolysis Bullosa
Fetal Blood
Blood Platelets
6 Citations

Alternative donor transplant of benign primary hematologic disorders

Tolar, J., Sodani, P. & Symons, H. Jan 1 2015 In : Bone Marrow Transplantation. 50, 5, p. 619-627 9 p.

Research output: Contribution to journalReview article

Tissue Donors
Unrelated Donors
Siblings
Hemoglobinopathies
Fetal Blood
2 Citations
Cell Transplantation
Haplotypes
Tissue Donors
Confidence Intervals
Siblings
3 Citations
Germ Cell and Embryonal Neoplasms
MicroRNAs
Methylation
Histology
Stem Cells
19 Citations

Cyclophosphamide conditioning in patients with severe aplastic anaemia given unrelated marrow transplantation: A phase 1-2 dose de-escalation study

Anderlini, P. , Wu, J. , Gersten, I. , Ewell, M. , Tolar, J. , Antin, J. H. , Adams, R. , Arai, S. , Eames, G. , Horwitz, M. E. , McCarty, J. , Nakamura, R. , Pulsipher, M. A. , Rowley, S. , Leifer, E. , Carter, S. L. , DiFronzo, N. L. , Horowitz, M. M. , Confer, D. , Deeg, H. J. & 1 others Eapen, M. Jan 1 2015 In : The Lancet Haematology. 2, 9, p. e367-e375

Research output: Contribution to journalArticle

Aplastic Anemia
Cyclophosphamide
Transplantation
Bone Marrow
Transplants
19 Citations

Derivation and high engraftment of patient-specific cardiomyocyte sheet using induced pluripotent stem cells generated from adult cardiac fibroblast

Zhang, L., Guo, J., Zhang, P., Xiong, Q., Wu, S. C., Xia, L., Roy, S. S., Tolar, J., O'Connell, T. D., Kyba, M., Liao, K. & Zhang, J. Jan 1 2015 In : Circulation: Heart Failure. 8, 1, p. 156-166 11 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Cardiac Myocytes
Fibroblasts
Transplantation
Wounds and Injuries
50 Citations

Fanconi anemia gene editing by the CRISPR/Cas9 system

Osborn, M. J., Gabriel, R., Webber, B. R., Defeo, A. P., McElroy, A. N., Jarjour, J., Starker, C. G., Wagner, J. E., Joung, J. K., Voytas, D. F., Von Kalle, C., Schmidt, M., Blazar, B. R. & Tolar, J. Jan 1 2015 In : Human gene therapy. 26, 2, p. 114-126 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Fanconi Anemia
Deoxyribonuclease I
DNA Repair-Deficiency Disorders
Genome
6 Citations

From marrow to matrix: Novel gene and cell therapies for epidermolysis bullosa

Webber, B. R. & Tolar, J. Jan 1 2015 In : Molecular Therapy. 23, 6, p. 987-992 6 p.

Research output: Contribution to journalReview article

Epidermolysis Bullosa
Cell- and Tissue-Based Therapy
Genetic Therapy
Bone Marrow
Targeted Gene Repair

From Mesoderm to Mesodermatology: Bone Marrow Mesenchymal Cells Heal Skin Wounds

Tolarova, M. & Tolar, J. Aug 1 2015 In : Molecular Therapy. 23, 8, p. 1283-1284 2 p.

Research output: Contribution to journalComment/debate

Epidermolysis Bullosa Dystrophica
Mesoderm
Mesenchymal Stromal Cells
Bone Marrow Cells
Wound Healing