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2017
6 Citations

Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation

Dietz, A. C., Mehta, P. A., Vlachos, A., Savage, S. A., Bresters, D., Tolar, J., Boulad, F., Dalle, J. H., Bonfim, C., de la Fuente, J., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P., May 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 5, p. 726-735 10 p.

Research output: Contribution to journalArticle

Cell Transplantation
Fanconi Anemia
Bone Marrow
Pediatrics
Transplants
8 Citations
Fanconi Anemia
Cell Transplantation
Investigational Therapies
Graft vs Host Disease
Transplants
Fetal Blood
Transplantation
Neutrophils
Blood Platelets
Incidence
2 Citations

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines

Hippen, K. L., O'Connor, R. S., Lemire, A. M., Saha, A., Hanse, E. A., Tennis, N. C., Merkel, S. C., Kelekar, A., Riley, J. L., Levine, B. L., June, C. H., Turka, L. A., Kean, L. S., MacMillan, M. L., Miller, J. S., Wagner, J. E., Munn, D. H. & Blazar, B. R., Dec 1 2017, In : American Journal of Transplantation. 17, 12, p. 3098-3113 16 p.

Research output: Contribution to journalArticle

Kynurenine
Regulatory T-Lymphocytes
Tryptophan
Interleukin-2
Graft vs Host Disease
3 Citations

Late Effects Screening Guidelines after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement From the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects After Pediatric HCT

Dietz, A. C., Savage, S. A., Vlachos, A., Mehta, P. A., Bresters, D., Tolar, J., Bonfim, C., Dalle, J. H., de la Fuente, J., Skinner, R., Boulad, F., Duncan, C. N., Baker, K. S., Pulsipher, M. A., Lipton, J. M., Wagner, J. E. & Alter, B. P., Sep 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 9, p. 1422-1428 7 p.

Research output: Contribution to journalArticle

Cell Transplantation
Bone Marrow
Guidelines
Pediatrics
Transplants
Risk Management
Ice
Immunocompromised Host
Mycobacterium
Hematopoietic Stem Cells
3 Citations

Matching at Human Leukocyte Antigen-C Improved the Outcomes after Double Umbilical Cord Blood Transplantation for Recipients of Two to Four of Six Human Leukocyte Antigen–Matched Grafts

Brunstein, C. G., Cutler, C. S., DeFor, T. E., Kim, H., Bejanyan, N., Garfall, A., Verneris, M. R., Chen, Y. B., Warlick, E. D., Spitzer, T., Miller, J. S., Antin, J. H., Weisdorf, D. J., Soiffer, R., Wagner, J. E. & Ballen, K. K., Jan 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 1, p. 126-133 8 p.

Research output: Contribution to journalArticle

HLA-C Antigens
HLA Antigens
Fetal Blood
Transplantation
Transplants
8 Citations

Optimal Practices in Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies

Barker, J. N., Kurtzberg, J., Ballen, K., Boo, M., Brunstein, C., Cutler, C., Horwitz, M., Milano, F., Olson, A., Spellman, S., Wagner, J. E., Delaney, C. & Shpall, E., Jun 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 6, p. 882-896 15 p.

Research output: Contribution to journalReview article

Unrelated Donors
Hematologic Neoplasms
Fetal Blood
Transplantation
Graft vs Host Disease
8 Citations

Optimization of cGMP purification and expansion of umbilical cord blood–derived T-regulatory cells in support of first-in-human clinical trials

McKenna, D. H., Sumstad, D., Kadidlo, D. M., Batdorf, B., Lord, C. J., Merkel, S. C., Koellner, C. M., Curtsinger, J. M., June, C. H., Riley, J. L., Levine, B. L., Miller, J. S., Brunstein, C. G., Wagner, J. E., Blazar, B. R. & Hippen, K. L., Feb 1 2017, In : Cytotherapy. 19, 2, p. 250-262 13 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Fetal Blood
Clinical Trials
Graft vs Host Disease
Antigen-Presenting Cells
Fanconi Anemia
Mutation
Inborn Genetic Diseases
Bone Marrow
Phenotype
9 Citations

The Second Pediatric Blood and Marrow Transplant Consortium International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: Defining the Unique Late Effects of Children Undergoing Hematopoietic Cell Transplantation for Immune Deficiencies, Inherited Marrow Failure Disorders, and Hemoglobinopathies

Dietz, A. C., Duncan, C. N., Alter, B. P., Bresters, D., Cowan, M. J., Notarangelo, L., Rosenberg, P. S., Shenoy, S., Skinner, R., Walters, M. C., Wagner, J., Baker, K. S. & Pulsipher, M. A., Jan 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 1, p. 24-29 6 p.

Research output: Contribution to journalArticle

Hemoglobinopathies
Cell Transplantation
Transplantation
Bone Marrow
Pediatrics

Umbilical Cord Blood Transplantation in Children with Acute Leukemia: Impact of Conditioning on Transplantation Outcomes

Eapen, M., Kurtzberg, J., Zhang, M. J., Hattersely, G., Fei, M., Mendizabal, A., Chan, K. W., De Oliveira, S., Schultz, K. R., Wall, D., Horowitz, M. M. & Wagner, J. E., Oct 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 10, p. 1714-1721 8 p.

Research output: Contribution to journalArticle

Transplantation Conditioning
Fetal Blood
Leukemia
Transplantation
Survival
2016
56 Citations

CD56 dim CD57+ NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT

Cichocki, F., Cooley, S., Davis, Z., DeFor, T. E., Schlums, H., Zhang, B., Brunstein, C. G., Blazar, B. R., Wagner, J., Diamond, D. J., Verneris, M. R., Bryceson, Y. T., Weisdorf, D. J. & Miller, J. S., Feb 1 2016, In : Leukemia. 30, 2, p. 456-463 8 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Natural Killer Cells
Leukemia
Transplants
Recurrence
7 Citations

CRISPR/Cas9 targeted gene editing and cellular engineering in fanconi anemia

Osborn, M. J., Lonetree, C. L., Webber, B. R., Patel, D., Dunmire, S., Defeo, A. P., McElroy, A. N., Macmillan, M. L., Wagner, J. E., Blazar, B. R. & Tolar, J., Oct 15 2016, In : Stem Cells and Development. 25, 20, p. 1591-1603 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Cell Engineering
Fanconi Anemia
Induced Pluripotent Stem Cells
Genes
7 Citations
Fanconi Anemia
Cell Transplantation
Insulin Resistance
Bone and Bones
Health

Establishing the UCB graft potentiality

Wagner, J. E., May 12 2016, In : Blood. 127, 19, p. 2272-2274 3 p.

Research output: Contribution to journalArticle

Aldehyde Dehydrogenase
Fetal Blood
Reproducibility of Results
Grafts
Blood
4 Citations

Fatal myocarditis associated with HHV-6 following immunosuppression in two children

Stefanski, H. E., Thibert, K. A., Pritchett, J., Prusty, B. K., Wagner, J. E. & Lund, T. C., Jan 1 2016, In : Pediatrics. 137, 1, e20151352

Research output: Contribution to journalArticle

Human Herpesvirus 6
Myocarditis
Immunosuppression
Herpesviridae Infections
Hematopoietic Stem Cell Transplantation

Hematopoietic Cell Transplantation for Fanconi Anemia

Wagner, J. E., Tolar, J., Auerbach, A. D. & MacMillan, M. L., Jan 1 2016, Thomas' Hematopoietic Cell Transplantation: Fifth Edition. Wiley Blackwell, Vol. 2-2, p. 923-946 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fanconi Anemia
Cell Transplantation
Bone Marrow
Radiation
Inborn Genetic Diseases
11 Citations
Fetal Blood
Transplantation
Alleles
Treatment Failure
Leukemia
3 Citations
Graft vs Host Disease
Helper-Inducer T-Lymphocytes
Fetal Blood
Transplantation
B-Lymphocytes
7 Citations
Leuprolide
Cell Transplantation
Gonadotropin-Releasing Hormone
Observation
Transplants
2 Citations

Paternal or Maternal Uniparental Disomy of Chromosome 16 Resulting in Homozygosity of a Mutant Allele Causes Fanconi Anemia

Donovan, F. X., Kimble, D. C., Kim, Y., Lach, F. P., Harper, U., Kamat, A., Jones, M., Sanborn, E. M., Tryon, R., Wagner, J. E., Macmillan, M. L., Ostrander, E. A., Auerbach, A. D., Smogorzewska, A. & Chandrasekharappa, S. C., May 1 2016, In : Human Mutation. 37, 5, p. 465-468 4 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Uniparental Disomy
Alleles
Mothers
Chromosomes, Human, Pair 16
3 Citations

Personalized fludarabine dosing to reduce nonrelapse mortality in hematopoietic stem-cell transplant recipients receiving reduced intensity conditioning

Sanghavi, K., Wiseman, A., Kirstein, M. N., Cao, Q., Brundage, R., Jensen, K., Rogosheske, J., Kurtzweil, A., Long-Boyle, J., Wagner, J., Warlick, E. D., Brunstein, C. G., Weisdorf, D. J. & Jacobson, P. A., Sep 1 2016, In : Translational Research. 175, p. 103-115.e4

Research output: Contribution to journalArticle

Transplants
Hematopoietic Stem Cells
Stem cells
Mortality
Cell Transplantation
75 Citations

Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

Wagner, J. E., Brunstein, C. G., Boitano, A. E., Defor, T. E., McKenna, D., Sumstad, D., Blazar, B. R., Tolar, J., Le, C., Jones, J., Cooke, M. P. & Bleul, C. C., Jan 7 2016, In : Cell Stem Cell. 18, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Fetal Blood
Transplants
Aryl Hydrocarbon Receptors
Hematopoietic Stem Cell Transplantation
13 Citations
Cell Transplantation
Graft vs Host Disease
Fetal Blood
Incidence
Recurrence
1 Citations
Mycophenolic Acid
Graft vs Host Disease
Sirolimus
Fetal Blood
Transplantation
9 Citations
Adoptive Transfer
Cell Transplantation
Natural Killer Cells
Transplants
Neoplasms

Toxic epidermal necrolysis in recessive dystrophic epidermolysis bullosa following bone marrow transplantation

Boull, C. L., Hylwa, S. A., Sajic, D., Wagner, J. E., Tolar, J. & Hook, K. P., Jun 1 2016, In : Journal of Pediatrics. 173, p. 242-244 3 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa Dystrophica
Stevens-Johnson Syndrome
Bone Marrow Transplantation
Epidermolysis Bullosa
Re-Epithelialization
81 Citations

Umbilical cord blood-derived T regulatory cells to prevent GVHD: Kinetics, toxicity profile, and clinical effect

Brunstein, C. G., Miller, J. S., McKenna, D. H., Hippen, K. L., DeFor, T. E., Sumstad, D., Curtsinger, J., Verneris, M. R., MacMillan, M. L., Levine, B. L., Riley, J. L., June, C. H., Le, C., Weisdorf, D. J., McGlave, P. B., Blazar, B. R. & Wagner, J. E., Feb 25 2016, In : Blood. 127, 8, p. 1044-1051 8 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Regulatory T-Lymphocytes
Fetal Blood
Grafts
Toxicity
3 Citations
Fetal Blood
Acute Myeloid Leukemia
Transplantation
2015
7 Citations

A biologic Velcro patch

Tolar, J. & Wagner, J. E., Jan 22 2015, In : New England Journal of Medicine. 372, 4, p. 382-384 3 p.

Research output: Contribution to journalArticle

Collagen Type VII
Epidermolysis Bullosa Dystrophica
Induced Pluripotent Stem Cells
Combined Modality Therapy
Skin Transplantation
21 Citations
KIR Receptors
Cell Transplantation
Cytomegalovirus
Natural Killer Cells
Tissue Donors
86 Citations

A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination

Wang, A. T., Kim, T., Wagner, J. E., Conti, B. A., Lach, F. P., Huang, A. L., Molina, H., Sanborn, E. M., Zierhut, H., Cornes, B. K., Abhyankar, A., Sougnez, C., Gabriel, S. B., Auerbach, A. D., Kowalczykowski, S. C. & Smogorzewska, A., Jan 1 2015, In : Molecular Cell. 59, 3, p. 478-490 13 p.

Research output: Contribution to journalArticle

Recombinational DNA Repair
Homologous Recombination
Recombinases
Mutation
DNA
32 Citations

Advances in umbilical cord blood manipulation-from niche to bedside

Lund, T. C., Boitano, A. E., Delaney, C. S., Shpall, E. J. & Wagner, J. E., Mar 28 2015, In : Nature Reviews Clinical Oncology. 12, 3, p. 163-174 12 p.

Research output: Contribution to journalReview article

Hematopoietic Stem Cells
Fetal Blood
Bone Marrow
Allografts
Transplantation
41 Citations
Fanconi Anemia
Cell Transplantation
Antilymphocyte Serum
Tissue Donors
Cyclophosphamide
3 Citations
Cell Transplantation
Haplotypes
Tissue Donors
Confidence Intervals
Siblings
11 Citations

Bone mineral density in children with fanconi anemia after hematopoietic cell transplantation

Petryk, A., Polgreen, L. E., Barnum, J. L., Zhang, L., Hodges, J. S., Baker, K. S., Wagner, J. E., Steinberger, J. & MacMillan, M. L., Jan 1 2015, In : Biology of Blood and Marrow Transplantation. 21, 5, p. 894-899 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Cell Transplantation
Bone Density
Bone and Bones
Neoplasms
1 Citations

Cell therapy product administration and safety: Data capture and analysis from the Production Assistance for Cellular Therapies (PACT) program

Lindblad, R. W., Ibenana, L., Wagner, J. E., McKenna, D. H., Hei, D. J., Hematti, P., Couture, L. A., Silberstein, L. E., Armant, M., Rooney, C. M., Gee, A. P., Welniak, L. A., Heath Mondoro, T., Wood, D. A. & Styers, D., Jan 1 2015, In : Transfusion. 55, 3, p. 674-679 6 p.

Research output: Contribution to journalReview article

Factual Databases
Postmarketing Product Surveillance
Forms and Records Control
National Heart, Lung, and Blood Institute (U.S.)
Adoptive Immunotherapy
53 Citations

Fanconi anemia gene editing by the CRISPR/Cas9 system

Osborn, M. J., Gabriel, R., Webber, B. R., Defeo, A. P., McElroy, A. N., Jarjour, J., Starker, C. G., Wagner, J. E., Joung, J. K., Voytas, D. F., Von Kalle, C., Schmidt, M., Blazar, B. R. & Tolar, J., Jan 1 2015, In : Human Gene Therapy. 26, 2, p. 114-126 13 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Fanconi Anemia
Deoxyribonuclease I
DNA Repair-Deficiency Disorders
Genome
17 Citations
Mycophenolic Acid
Graft vs Host Disease
Fetal Blood
Transplantation
Cell Transplantation
6 Citations
Cryopreservation
Fetal Blood
Transplantation
Blood Cells
Neutrophils
9 Citations

In Vivo T Cell Depletion with Myeloablative Regimens on Outcomes after Cord Blood Transplantation for Acute Lymphoblastic Leukemia in Children

Ponce, D. M., Eapen, M., Sparapani, R., O'Brien, T. A., Chan, K. W., Chen, J., Craddock, J., Schultz, K. R., Wagner, J. E., Perales, M. A. & Barker, J. N., Dec 1 2015, In : Biology of Blood and Marrow Transplantation. 21, 12, p. 2173-2179 7 p.

Research output: Contribution to journalArticle

Antilymphocyte Serum
Fetal Blood
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Transplantation
T-Lymphocytes
4 Citations

One-unit versus two-unit cord-blood transplantation

Wagner, J. E., Eapen, M. & Kurtzberg, J., Jan 15 2015, In : The New England journal of medicine. 372, 3, 1 p.

Research output: Contribution to journalLetter

Cord Blood Stem Cell Transplantation
Hematologic Neoplasms
Fetal Blood
Transplantation
5 Citations
Cell Transplantation
Transplants
Nerve Growth Factor
Confidence Intervals
Neutrophils
1 Citations

Second Allogeneic Hematopoietic Cell Transplantation for Patients with Fanconi Anemia and Bone Marrow Failure

Ayas, M. , Eapen, M. , Le-Rademacher, J. , Carreras, J. , Abdel-Azim, H. , Alter, B. P. , Anderlini, P. , Battiwalla, M. , Bierings, M. , Buchbinder, D. K. , Bonfim, C. , Camitta, B. M. , Fasth, A. L. , Gale, R. P. , Lee, M. A. , Lund, T. C. , Myers, K. C. , Olsson, R. F. , Page, K. M. , Prestidge, T. D. & 6 others Radhi, M., Shah, A. J., Schultz, K. R., Wirk, B., Wagner, J. E. & Deeg, H. J., Oct 1 2015, In : Biology of Blood and Marrow Transplantation. 21, 10, p. 1790-1795 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Cell Transplantation
Bone Marrow
Transplants
Graft Survival
3 Citations

The authors reply

Wagner, J. E., Eapen, M. & Kurtzberg, J., Jan 1 2015, In : New England Journal of Medicine. 372, 3, 1 p.

Research output: Contribution to journalLetter

2014
4 Citations

An Update from the United States National Heart, Lung, and Blood Institute-funded Production Assistance for Cellular Therapies (PACT) Program: A Decade of Cell Therapy

Wood, D., Wesselschmidt, R., Hematti, P., Gee, A. P., Rooney, C., Silberstein, L., Armant, M., Couture, L., Wagner, J. E., Mckenna, D. H., Hei, D., Mondoro, T. H., Welniak, L. & Lindblad, R., Jan 1 2014, In : Clinical and Translational Science. 7, 2, p. 93-99 7 p.

Research output: Contribution to journalArticle

National Heart, Lung, and Blood Institute (U.S.)
Program Development
Translational Medical Research
Cell- and Tissue-Based Therapy
Therapeutics
16 Citations
Fetal Blood
Transplantation
Tissue Donors
Recurrence
Confidence Intervals
15 Citations

Comprehensive analysis of pathogenic deletion variants in Fanconi anemia genes

Flynn, E. K., Kamat, A., Lach, F. P., Donovan, F. X., Kimble, D. C., Narisu, N., Sanborn, E., Boulad, F., Davies, S. M., Gillio, A. P., Harris, R. E., Macmillan, M. L., Wagner, J. E., Smogorzewska, A., Auerbach, A. D., Ostrander, E. A. & Chandrasekharappa, S. C., Nov 1 2014, In : Human Mutation. 35, 11, p. 1342-1353 12 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Genes
Organism Cloning
Mutation
Comparative Genomic Hybridization
5 Citations
Hematopoietic Stem Cell Transplantation
Myelodysplastic Syndromes
Natural History
Leukemia
Tissue Donors