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2017

Allogeneic hematopoietic cell transplantation in morphologic leukemia-free aplastic state

Rashidi, A., Ali, A. M., Vij, K. R., Shanley, R., Romee, R., Cooley, S. A., Westervelt, P., DiPersio, J. F., Miller, J. S., Weisdorf, D. J. & Ustun, C., Sep 1 2017, In : American Journal of Hematology. 92, 9, p. E549-E552

Research output: Contribution to journalLetter

Cell Transplantation
Leukemia
1 Citations
5 Citations

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant

Tkachev, V., Furlan, S. N., Watkins, B., Hunt, D. J., Betty Zheng, H., Panoskaltsis-Mortari, A., Betz, K., Brown, M., Schell, J. B., Zeleski, K., Yu, A., Kirby, I., Cooley, S., Miller, J. S., Blazar, B. R., Casson, D., Bland-Ward, P. & Kean, L. S., Sep 20 2017, In : Science Translational Medicine. 9, 408, eaan3085

Research output: Contribution to journalArticle

Sirolimus
Graft vs Host Disease
T-Lymphocytes
Transplants
Th1 Cells
Hematologic Neoplasms
Blood Donors
Fetal Blood
Dendritic Cells
Siblings
5 Citations
Antibody-Dependent Cell Cytotoxicity
Natural Killer Cells
Interleukin-15
Neoplastic Stem Cells
Interferon-gamma
8 Citations

GSK3 inhibition drives maturation of NK cells and enhances their antitumor activity

Cichocki, F. , Valamehr, B. , Bjordahl, R. , Zhang, B. , Rezner, B. , Rogers, P. , Gaidarova, S. , Moreno, S. , Tuininga, K. , Dougherty, P. , McCullar, V. , Howard, P. , Sarhan, D. , Taras, E. , Schlums, H. , Abbot, S. , Shoemaker, D. , Bryceson, Y. T. , Blazar, B. R. , Wolchko, S. & 2 others Cooley, S. & Miller, J. S., Oct 15 2017, In : Cancer Research. 77, 20, p. 5664-5675 12 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Neoplasms
Phosphotransferases
Immunologic Monitoring
Interleukin-15
4 Citations

HLA-Bw4-I-80 isoform differentially influences clinical outcome as compared to HLA-Bw4-T-80 and HLA-A-Bw4 isoforms in rituximab or dinutuximab-based cancer immunotherapy

Erbe, A. K., Wang, W., Reville, P. K., Carmichael, L., Kim, K. M., Mendonca, E. A., Song, Y., Hank, J. A., London, W. B., Naranjo, A., Hong, F., Hogarty, M. D., Maris, J. M., Park, J. R., Ozkaynak, M. F., Miller, J. S., Gilman, A. L., Kahl, B., Yu, A. L. & Sondel, P. M., Jun 12 2017, In : Frontiers in Immunology. 8, JUN, 675

Research output: Contribution to journalArticle

HLA-A Antigens
Immunotherapy
Epitopes
Protein Isoforms
KIR Receptors
13 Citations

IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer

Felices, M., Chu, S., Kodal, B., Bendzick, L., Ryan, C., Lenvik, A. J., Boylan, K. L. M., Wong, H. C., Skubitz, A. P. N., Miller, J. S. & Geller, M. A., Jun 1 2017, In : Gynecologic Oncology. 145, 3, p. 453-461 9 p.

Research output: Contribution to journalArticle

Interleukin-15
Natural Killer Cells
Ovarian Neoplasms
Ascites
ALT-803
2 Citations

In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines

Hippen, K. L., O'Connor, R. S., Lemire, A. M., Saha, A., Hanse, E. A., Tennis, N. C., Merkel, S. C., Kelekar, A., Riley, J. L., Levine, B. L., June, C. H., Turka, L. A., Kean, L. S., MacMillan, M. L., Miller, J. S., Wagner, J. E., Munn, D. H. & Blazar, B. R., Dec 1 2017, In : American Journal of Transplantation. 17, 12, p. 3098-3113 16 p.

Research output: Contribution to journalArticle

Kynurenine
Regulatory T-Lymphocytes
Tryptophan
Interleukin-2
Graft vs Host Disease
3 Citations

Matching at Human Leukocyte Antigen-C Improved the Outcomes after Double Umbilical Cord Blood Transplantation for Recipients of Two to Four of Six Human Leukocyte Antigen–Matched Grafts

Brunstein, C. G., Cutler, C. S., DeFor, T. E., Kim, H., Bejanyan, N., Garfall, A., Verneris, M. R., Chen, Y. B., Warlick, E. D., Spitzer, T., Miller, J. S., Antin, J. H., Weisdorf, D. J., Soiffer, R., Wagner, J. E. & Ballen, K. K., Jan 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 1, p. 126-133 8 p.

Research output: Contribution to journalArticle

HLA-C Antigens
HLA Antigens
Fetal Blood
Transplantation
Transplants
7 Citations
Natural Killer Cells
Immunotherapy
Neoplasms
Neoplasm Antigens
Tumor Escape
8 Citations

Optimization of cGMP purification and expansion of umbilical cord blood–derived T-regulatory cells in support of first-in-human clinical trials

McKenna, D. H., Sumstad, D., Kadidlo, D. M., Batdorf, B., Lord, C. J., Merkel, S. C., Koellner, C. M., Curtsinger, J. M., June, C. H., Riley, J. L., Levine, B. L., Miller, J. S., Brunstein, C. G., Wagner, J. E., Blazar, B. R. & Hippen, K. L., Feb 1 2017, In : Cytotherapy. 19, 2, p. 250-262 13 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Fetal Blood
Clinical Trials
Graft vs Host Disease
Antigen-Presenting Cells
4 Citations

Recipient HLA-C Haplotypes and microRNA 148a/b Binding Sites Have No Impact on Allogeneic Hematopoietic Cell Transplantation Outcomes

Hoff, G. A., Fischer, J. C., Hsu, K., Cooley, S., Miller, J. S., Wang, T., Haagenson, M., Spellman, S., Lee, S. J., Uhrberg, M., Venstrom, J. M. & Verneris, M. R., Jan 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 1, p. 153-160 8 p.

Research output: Contribution to journalArticle

HLA-C Antigens
Cell Transplantation
MicroRNAs
Haplotypes
Binding Sites
Adoptive Transfer
Natural Killer Cells
T-Lymphocytes
Tissue Donors
Remission Induction
2016
19 Citations

Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells

Sarhan, D., Cichocki, F., Zhang, B., Yingst, A., Spellman, S. R., Cooley, S., Verneris, M. R., Blazar, B. R. & Miller, J. S., Oct 1 2016, In : Cancer Research. 76, 19, p. 5696-5706 11 p.

Research output: Contribution to journalArticle

Natural Killer Cells
T-Lymphocytes
Reactive Oxygen Species
Costimulatory and Inhibitory T-Cell Receptors
Neoplasms
26 Citations

Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

Koehl, U., Kalberer, C., Spanholtz, J., Lee, D. A., Miller, J. S., Cooley, S., Lowdell, M., Uharek, L., Klingemann, H., Curti, A., Leung, W. & Alici, E., Apr 2 2016, In : OncoImmunology. 5, 4

Research output: Contribution to journalReview article

Donor Selection
Natural Killer Cells
Quality Control
Antigen Receptors
Cell- and Tissue-Based Therapy
56 Citations

CD56 dim CD57+ NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT

Cichocki, F., Cooley, S., Davis, Z., DeFor, T. E., Schlums, H., Zhang, B., Brunstein, C. G., Blazar, B. R., Wagner, J., Diamond, D. J., Verneris, M. R., Bryceson, Y. T., Weisdorf, D. J. & Miller, J. S., Feb 1 2016, In : Leukemia. 30, 2, p. 456-463 8 p.

Research output: Contribution to journalArticle

Cytomegalovirus
Natural Killer Cells
Leukemia
Transplants
Recurrence
15 Citations

Diversification and functional specialization of human NK cell subsets

Cichocki, F., Schlums, H., Theorell, J., Tesi, B., Miller, J. S., Ljunggren, H. G. & Bryceson, Y. T., Feb 1 2016, In : Current Topics in Microbiology and Immunology. 395, p. 63-93 31 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Immunologic Monitoring
Immunity
Cytokines
Disease Susceptibility
8 Citations

Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation

Bachanova, V., Weisdorf, D. J., Wang, T., Marsh, S. G. E., Trachtenberg, E., Haagenson, M. D., Spellman, S. R., Ladner, M., Guethlein, L. A., Parham, P., Miller, J. S. & Cooley, S. A., Sep 1 2016, In : Biology of Blood and Marrow Transplantation. 22, 9, p. 1602-1607 6 p.

Research output: Contribution to journalArticle

KIR Receptors
Unrelated Donors
Non-Hodgkin's Lymphoma
Disease-Free Survival
Transplantation
13 Citations

Enhanced ADCC and NK cell activation of an anticarcinoma bispecific antibody by genetic insertion of a modified IL-15 cross-linker

Schmohl, J. U., Felices, M., Taras, E., Miller, J. S. & Vallera, D. A., Aug 1 2016, In : Molecular Therapy. 24, 7, p. 1312-1322 11 p.

Research output: Contribution to journalArticle

Bispecific Antibodies
Antibody-Dependent Cell Cytotoxicity
Interleukin-15
Natural Killer Cells
Cytokines
43 Citations

Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL nucleases

Osborn, M. J. , Webber, B. R. , Knipping, F. , Lonetree, C. L. , Tennis, N. , DeFeo, A. P. , McElroy, A. N. , Starker, C. G. , Lee, C. , Merkel, S. , Lund, T. C. , Kelly-Spratt, K. S. , Jensen, M. C. , Voytas, D. F. , Von Kalle, C. , Schmidt, M. , Gabriel, R. , Hippen, K. L. , Miller, J. S. , Scharenberg, A. M. & 2 others Tolar, J. & Blazar, B. R., Mar 1 2016, In : Molecular Therapy. 24, 3, p. 570-581 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
T-Lymphocytes
T-Cell Antigen Receptor
Adoptive Immunotherapy
Neoplasm Antigens
9 Citations

Generation of BiKEs and TriKEs to improve NK cell-mediated targeting of tumor cells

Felices, M., Lenvik, T. R., Davis, Z. B., Miller, J. S. & Vallera, D. A., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 333-346 14 p. (Methods in Molecular Biology; vol. 1441)

Research output: Chapter in Book/Report/Conference proceedingChapter

Natural Killer Cells
Antibodies
Neoplasms
Immunotherapy
Natural Killer Cell Receptors
15 Citations

Heterodimeric Bispecific Single Chain Variable Fragments (scFv) Killer Engagers (BiKEs) Enhance NK-cell Activity Against CD133+ Colorectal Cancer Cells

Schmohl, J. U., Gleason, M. K., Dougherty, P. R., Miller, J. S. & Vallera, D. A., Jun 1 2016, In : Targeted Oncology. 11, 3, p. 353-361 9 p.

Research output: Contribution to journalArticle

Single-Chain Antibodies
Natural Killer Cells
Colorectal Neoplasms
Neoplastic Stem Cells
Pharmaceutical Preparations
46 Citations
Interleukin-15
Natural Killer Cells
Antigens
Cell Degranulation
Survival
24 Citations

Immunodynamics: A cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials

Kohrt, H. E. , Tumeh, P. C. , Benson, D. , Bhardwaj, N. , Brody, J. , Formenti, S. , Fox, B. A. , Galon, J. , June, C. H. , Kalos, M. , Kirsch, I. , Kleen, T. , Kroemer, G. , Lanier, L. , Levy, R. , Lyerly, H. K. , Maecker, H. , Marabelle, A. , Melenhorst, J. , Miller, J. & 15 others Melero, I., Odunsi, K., Palucka, K., Peoples, G., Ribas, A., Robins, H., Robinson, W., Serafini, T., Sondel, P., Vivier, E., Weber, J., Wolchok, J., Zitvogel, L., Disis, M. L. & Cheever, M. A., Mar 15 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 15

Research output: Contribution to journalReview article

Immunologic Monitoring
Immunotherapy
Clinical Trials
Pharmacokinetics
Neoplasms
11 Citations
Fetal Blood
Transplantation
Alleles
Treatment Failure
Leukemia
20 Citations

Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer

Hermanson, D. L., Bendzick, L., Pribyl, L., McCullar, V., Vogel, R. I., Miller, J. S., Geller, M. A. & Kaufman, D. S., Jan 1 2016, In : Stem Cells. 34, 1, p. 93-101 9 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Natural Killer Cells
Ovarian Neoplasms
Therapeutics
Tumor Burden
3 Citations
Graft vs Host Disease
Helper-Inducer T-Lymphocytes
Fetal Blood
Transplantation
B-Lymphocytes
7 Citations
Cell Transplantation
Hematologic Neoplasms
Tissue Donors
Lymphocytes
Drug Therapy

Natural Killer Cells and Allogeneic Hematopoietic Cell Transplantation

Verneris, M. R. & Miller, J. S., Jan 1 2016, Thomas' Hematopoietic Cell Transplantation: Fifth Edition. Wiley Blackwell, Vol. 1-2, p. 126-138 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cell Transplantation
Natural Killer Cells
Immune System
KIR Receptors
Unrelated Donors

NK cells pave the road for alloengraftment

Felices, M. & Miller, J. S., Mar 3 2016, In : Blood. 127, 9, p. 1083-1084 2 p.

Research output: Contribution to journalShort survey

Grafts
Natural Killer Cells
Blood
Transplants
6 Citations

Proceedings from the Second Haploidentical Stem Cell Transplantation Symposium-Haplo2014, San Francisco, California, December 4, 2014

Al Malki, M. M., Horowitz, M., Handgretinger, R., Leung, W., Roy, D. C., Huang, X. J., Fuchs, E., Locatelli, F., Blaise, D., Mineishi, S., Martelli, M., Miller, J., June, C., Ai, H. S., Luznik, L., Mavilio, D., Lugli, E., van den Brink, M. R. M., Champlin, R. E. & Ciurea, S. O., Apr 1 2016, In : Biology of Blood and Marrow Transplantation. 22, 4, p. 594-604 11 p.

Research output: Contribution to journalArticle

San Francisco
Stem Cell Transplantation
Transplantation
Recurrence
Unrelated Donors
26 Citations

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

Saha, A. , O'Connor, R. S. , Thangavelu, G. , Lovitch, S. B. , Dandamudi, D. B. , Wilson, C. B. , Vincent, B. G. , Tkachev, V. , Pawlicki, J. M. , Furlan, S. N. , Kean, L. S. , Aoyama, K. , Taylor, P. A. , Panoskaltsis-Mortari, A. , Foncea, R. , Ranganathan, P. , Devine, S. M. , Burrill, J. S. , Guo, L. , Sacristan, C. & 15 others Snyder, N. W., Blair, I. A., Milone, M. C., Dustin, M. L., Riley, J. L., Bernlohr, D. A., Murphy, W. J., Fife, B. T., Munn, D. H., Miller, J. S., Serody, J. S., Freeman, G. J., Sharpe, A. H., Turka, L. A. & Blazar, B. R., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2642-2660 19 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Tissue Donors
Ligands
T-Lymphocytes
Transplants
9 Citations

Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells

Furlan, S. N., Watkins, B., Tkachev, V., Cooley, S., Panoskaltsis-Mortari, A., Betz, K., Brown, M., Hunt, D. J., Schell, J. B., Zeleski, K., Yu, A., Giver, C. R., Waller, E. K., Miller, J. S., Blazar, B. R. & Kean, L. S., Nov 24 2016, In : Blood. 128, 21, p. 2568-2579 12 p.

Research output: Contribution to journalArticle

T-cells
Graft vs Host Disease
Systems Analysis
Grafts
Haplorhini
5 Citations

Targeting KIR blockade in multiple myeloma: Trouble in checkpoint paradise?

Felices, M. & Miller, J. S., Nov 1 2016, In : Clinical Cancer Research. 22, 21, p. 5161-5163 3 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Natural Killer Cells
Monocytes
IPH 2101
5 Citations

Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker

Schmohl, J. U., Felices, M., Todhunter, D., Taras, E., Miller, J. S. & Vallera, D. A., Jan 1 2016, In : Oncotarget. 7, 45, p. 73830-73844 15 p.

Research output: Contribution to journalArticle

Antibody-Dependent Cell Cytotoxicity
Interleukin-15
Natural Killer Cells
Cytokines
Neoplastic Stem Cells
9 Citations
Adoptive Transfer
Cell Transplantation
Natural Killer Cells
Transplants
Neoplasms
2 Citations

The society for immunotherapy of cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: Multiple myeloma, lymphoma, and acute leukemia

Boyiadzis, M. , Bishop, M. R. , Abonour, R. , Anderson, K. C. , Ansell, S. M. , Avigan, D. , Barbarotta, L. , Barrett, A. J. , Besien, K. , Bergsagel, P. L. , Borrello, I. , Brody, J. , Brufsky, J. , Cairo, M. , Chari, A. , Cohen, A. , Cortes, J. , Forman, S. J. , Friedberg, J. W. , Fuchs, E. J. & 28 others Gore, S. D., Jagannath, S., Kahl, B. S., Kline, J., Kochenderfer, J. N., Kwak, L. W., Levy, R., Lima, M., Litzow, M. R., Mahindra, A., Miller, J., Munshi, N. C., Orlowski, R. Z., Pagel, J. M., Porter, D. L., Russell, S. J., Schwartz, K., Shipp, M. A., Siegel, D., Stone, R. M., Tallman, M. S., Timmerman, J. M., Rhee, F., Waller, E. K., Welsh, A., Werner, M., Wiernik, P. H. & Dhodapkar, M. V., Dec 20 2016, In : Journal for ImmunoTherapy of Cancer. 4, 1, 90

Research output: Contribution to journalArticle

Hematologic Neoplasms
Multiple Myeloma
Immunotherapy
Lymphoma
Leukemia
81 Citations

Umbilical cord blood-derived T regulatory cells to prevent GVHD: Kinetics, toxicity profile, and clinical effect

Brunstein, C. G., Miller, J. S., McKenna, D. H., Hippen, K. L., DeFor, T. E., Sumstad, D., Curtsinger, J., Verneris, M. R., MacMillan, M. L., Levine, B. L., Riley, J. L., June, C. H., Le, C., Weisdorf, D. J., McGlave, P. B., Blazar, B. R. & Wagner, J. E., Feb 25 2016, In : Blood. 127, 8, p. 1044-1051 8 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Regulatory T-Lymphocytes
Fetal Blood
Grafts
Toxicity
20 Citations

Viraemia, immunogenicity, and survival outcomes of cytomegalovirus chimeric epitope vaccine supplemented with PF03512676 (CMVPepVax) in allogeneic haemopoietic stem-cell transplantation: Randomised phase 1b trial

Nakamura, R., Rosa, C. L., Longmate, J., Drake, J., Slape, C., Zhou, Q., Lampa, M. G., O'Donnell, M., Cai, J. L., Farol, L., Salhotra, A., Snyder, D. S., Aldoss, I., Forman, S. J., Miller, J. S., Zaia, J. A. & Diamond, D. J., Feb 1 2016, In : The Lancet Haematology. 3, 2, p. e87-e98

Research output: Contribution to journalArticle

Viremia
Stem Cell Transplantation
Cytomegalovirus
Epitopes
Vaccines
2015

ADAM17 and CD56lowCD16low NK cells

Romee, R. & Miller, J. S., Jan 1 2015, In : Haematologica. 100, 8

Research output: Contribution to journalLetter

CD56 Antigens
IgG Receptors
Immunophenotyping
Lymphocyte Subsets
Natural Killer Cells
21 Citations
KIR Receptors
Cell Transplantation
Cytomegalovirus
Natural Killer Cells
Tissue Donors
171 Citations

Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function

Schlums, H., Cichocki, F., Tesi, B., Theorell, J., Beziat, V., Holmes, T. D., Han, H., Chiang, S. C. C., Foley, B., Mattsson, K., Larsson, S., Schaffer, M., Malmberg, K. J., Ljunggren, H. G., Miller, J. S. & Bryceson, Y. T., Jan 1 2015, In : Immunity. 42, 3, p. 443-456 14 p.

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Epigenomics
Natural Killer Cells
Virus Diseases
Myeloid Cells
26 Citations

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Koehn, B. H., Apostolova, P., Haverkamp, J. M., Miller, J. S., McCullar, V., Tolar, J., Munn, D. H., Murphy, W. J., Brickey, W. J., Serody, J. S., Gabrilovich, D. I., Bronte, V., Murray, P. J., Ting, J. P. Y., Zeiser, R. & Blazar, B. R., Sep 24 2015, In : Blood. 126, 13, p. 1621-1628 8 p.

Research output: Contribution to journalArticle

Inflammasomes
Graft vs Host Disease
Grafts
Myeloid-Derived Suppressor Cells
Bone
10 Citations

Human group 3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation

Ahn, Y. O., Weeres, M. A., Neulen, M. L., Choi, J., Kang, S. H., Heo, D. S., Bergerson, R., Blazar, B. R., Miller, J. S. & Verneris, M. R., Jan 1 2015, In : European Journal of Immunology. 45, 8, p. 2335-2342 8 p.

Research output: Contribution to journalArticle

Interleukin-23
Interleukin-2
Lymphocytes
Tumor Necrosis Factor Ligand Superfamily Member 15
Receptors, Tumor Necrosis Factor, Member 25
7 Citations

Human natural killer cell microRNA: Differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs

Presnell, S. R., Al-Attar, A., Cichocki, F., Miller, J. S. & Lutz, C. T., Jan 1 2015, In : Genes and Immunity. 16, 1, p. 89-98 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Natural Killer Cells
Genes
Transforming Growth Factor beta
Cell Differentiation
25 Citations

Natural killer cell adoptive transfer therapy: Exploiting the first line of defense against cancer

Davis, Z. B., Felices, M., Verneris, M. R. & Miller, J. S., Jan 1 2015, In : Cancer Journal (United States). 21, 6, p. 486-491 6 p.

Research output: Contribution to journalReview article

Adoptive Transfer
Natural Killer Cells
Neoplasms
Therapeutics
Tumor Microenvironment
13 Citations

Phase i study of a bispecific ligand-directed toxin targeting CD22 and CD19 (DT2219) for refractory B-cell malignancies

Bachanova, V., Frankel, A. E., Cao, Q., Lewis, D., Grzywacz, B., Verneris, M. R., Ustun, C., Lazaryan, A., McClune, B., Warlick, E. D., Kantarjian, H., Weisdorf, D. J., Miller, J. S. & Vallera, D. A., Mar 15 2015, In : Clinical Cancer Research. 21, 6, p. 1267-1272 6 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Ligands
Neoplasms
Single-Chain Antibodies
Bispecific Antibodies
17 Citations

Regulation of adaptive NK cells and CD8 T cells by HLA-C correlates with allogeneic hematopoietic cell transplantation and with cytomegalovirus reactivation

Horowitz, A., Guethlein, L. A., Nemat-Gorgani, N., Norman, P. J., Cooley, S., Miller, J. S. & Parham, P., Nov 1 2015, In : Journal of Immunology. 195, 9, p. 4524-4536 13 p.

Research output: Contribution to journalArticle

HLA-C Antigens
Cell Transplantation
Cytomegalovirus
Natural Killer Cells
T-Lymphocytes