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2017

ABO blood group is associated with peripheral arterial disease in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA)

Pike, M. M., Larson, N. B., Wassel, C. L., Cohoon, K. P., Tsai, M. Y., Pankow, J. S., Hanson, N. Q., Decker, P. A., Berardi, C., Alexander, K. S., Cushman, M., Zakai, N. A. & Bielinski, S. J., May 1 2017, In : Thrombosis Research. 153, p. 1-6 6 p.

Research output: Contribution to journalArticle

Peripheral Arterial Disease
Blood Group Antigens
African Americans
Ankle Brachial Index
Atherosclerosis
11 Citations

A longitudinal study of iron status during pregnancy and the risk of gestational diabetes: findings from a prospective, multiracial cohort

Rawal, S., Hinkle, S. N., Bao, W., Zhu, Y., Grewal, J., Albert, P. S., Weir, N. L., Tsai, M. Y. & Zhang, C., Feb 1 2017, In : Diabetologia. 60, 2, p. 249-257 9 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Longitudinal Studies
Iron
Pregnancy
Ferritins
5 Citations
Carotid Artery Diseases
Apolipoproteins B
Carotid Intima-Media Thickness
LDL Lipoproteins
Lipoproteins
7 Citations

Association of air pollution exposures with high-density lipoprotein cholesterol and particle number: The multi-ethnic study of atherosclerosis

Bell, G., Mora, S., Greenland, P., Tsai, M., Gill, E. & Kaufman, J. D., May 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 5, p. 976-982 7 p.

Research output: Contribution to journalArticle

Air Pollution
HDL Lipoproteins
HDL Cholesterol
Atherosclerosis
Confidence Intervals
2 Citations

Cholesterol, lipoproteins and subclinical interstitial lung disease: The MESA study

Podolanczuk, A. J., Raghu, G., Tsai, M. Y., Kawut, S. M., Peterson, E., Sonti, R., Rabinowitz, D., Johnson, C., Barr, R. G., Stukovsky, K. H., Hoffman, E. A., Carr, J. J., Ahmed, F. S., Jacobs, D. R., Watson, K., Shea, S. J. & Lederer, D. J., Jan 27 2017, In : Thorax. 72, 5, p. 472-474 3 p.

Research output: Contribution to journalArticle

Interstitial Lung Diseases
Matrix Metalloproteinases
HDL Cholesterol
Lung Injury
Lipoproteins
1 Citations

Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations

Hu, Y., Tanaka, T., Zhu, J., Guan, W., Wu, J. H. Y., Psaty, B. M., McKnight, B., King, I. B., Sun, Q., Richard, M., Manichaikul, A., Frazier-Wood, A. C., Kabagambe, E. K., Hopkins, P. N., Ordovas, J. M., Ferrucci, L., Bandinelli, S., Arnett, D. K., Chen, Y. D. I., Liang, S. & 13 othersSiscovick, D. S., Tsai, M. Y., Rich, S. S., Fornage, M., Hu, F. B., Rimm, E. B., Jensen, M. K., Lemaitre, R. N., Mozaffarian, D., Steffen, L. M., Morris, A. P., Li, H. & Lin, X., May 1 2017, In : Journal of Lipid Research. 58, 5, p. 974-981 8 p.

Research output: Contribution to journalArticle

Meta-Analysis
Genome-Wide Association Study
Genes
Association reactions
Oleic Acid
1 Citations

Elevated Levels of Adhesion Proteins Are Associated with Low Ankle-Brachial Index: Multi-Ethnic Study of Atherosclerosis

Berardi, C., Wassel, C. L., Decker, P. A., Larson, N. B., Kirsch, P. S., Andrade, M. D., Tsai, M. Y., Pankow, J. S., Sale, M. M., Sicotte, H., Tang, W., Hanson, N. Q., McDermott, M. M., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2017, In : Angiology. 68, 4, p. 322-329 8 p.

Research output: Contribution to journalArticle

Ankle Brachial Index
Atherosclerosis
Proteins
Peripheral Arterial Disease
Secretory Leukocyte Peptidase Inhibitor
2 Citations
Open Access
Aortic Diseases
Lipoprotein(a)
Aortic Valve
Immunoassay
Coronary Disease
3 Citations

Genetic associations with lipoprotein subfraction measures differ by ethnicity in the multi-ethnic study of atherosclerosis (MESA)

Wang, Z., Manichukal, A., Goff, D. C., Mora, S., Ordovas, J. M., Pajewski, N. M., Post, W. S., Rotter, J. I., Sale, M. M., Santorico, S. A., Siscovick, D., Tsai, M. Y., Arnett, D. K., Rich, S. & Frazier-Wood, A. C., Jun 1 2017, In : Human Genetics. 136, 6, p. 715-726 12 p.

Research output: Contribution to journalArticle

Lipoproteins
Atherosclerosis
Hispanic Americans
Genome
African Americans

Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts

Mozaffarian, D., Dashti, H. S., Wojczynski, M. K., Chu, A. Y., Nettleton, J. A., Männistö, S., Kristiansson, K., Reedik, M., Lahti, J., Houston, D. K., Cornelis, M. C., Van Rooij, F. J. A., Dimitriou, M., Kanoni, S., Mikkilä, V., Steffen, L. M., De Oliveira Otto, M. C., Qi, L., Psaty, B., Djousse, L. & 45 othersRotter, J. I., Harald, K., Perola, M., Rissanen, H., Jula, A., Krista, F., Mihailov, E., Feitosa, M. F., Ngwa, J. S., Xue, L., Jacques, P. F., Perälä, M. M., Palotie, A., Liu, Y., Nalls, N. A., Ferrucci, L., Hernandez, D., Manichaikul, A., Tsai, M. Y., Kiefte-De Jong, J. C., Hofman, A., Uitterlinden, A. G., Rallidis, L., Ridker, P. M., Rose, L. M., Buring, J. E., Lehtimäki, T., Kähönen, M., Viikari, J., Lemaitre, R., Salomaa, V., Knekt, P., Metspalu, A., Borecki, I. B., Cupples, L. A., Eriksson, J. G., Kritchevsky, S. B., Bandinelli, S., Siscovick, D., Franco, O. H., Deloukas, P., Dedoussis, G., Chasman, D. I., Raitakari, O. & Tanaka, T., Dec 1 2017, In : PloS one. 12, 12, e0186456.

Research output: Contribution to journalArticle

Genome-Wide Association Study
meta-analysis
Fish
Meta-Analysis
Fishes
1 Citations

Hepatocyte growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease

Bielinski, S. J., Berardi, C., Decker, P. A., Larson, N. B., Bell, E. J., Pankow, J. S., Sale, M. M., Tang, W., Hanson, N. Q., Wassel, C. L., De Andrade, M., Budoff, M. J., Polak, J. F., Sicotte, H. & Tsai, M. Y., Aug 1 2017, In : Heart. 103, 15, p. 1185-1193 9 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Coronary Disease
Biomarkers
Hispanic Americans
African Americans

Long chain n-3 polyunsaturated fatty acids are not associated with circulating T-helper type 1 cells: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)

Sagawa, N., Olson, N. C., Ahuja, V., Vishnu, A., Doyle, M. F., Psaty, B. M., Jenny, N. S., Siscovick, D. S., Lemaitre, R. N., Steffen, L. M., Tsai, M. Y. & Sekikawa, A., Oct 1 2017, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 125, p. 37-42 6 p.

Research output: Contribution to journalArticle

Th1 Cells
Omega-3 Fatty Acids
Atherosclerosis
Association reactions
Plasmas

Low high-density lipoprotein cholesterol and particle concentrations are associated with greater levels of endothelial activation markers in Multi-Ethnic Study of Atherosclerosis participants

Steffen, B. T., Bielinski, S. J., Decker, P. A., Berardi, C., Larson, N. B., Pankow, J. S., Michos, E. D., Hanson, N. Q., Herrington, D. M. & Tsai, M. Y., Jul 1 2017, In : Journal of Clinical Lipidology. 11, 4, p. 955-963.e3

Research output: Contribution to journalArticle

HDL Lipoproteins
LDL Cholesterol
HDL Cholesterol
Atherosclerosis
Selectins
3 Citations

Meta-analysis of genome-wide association studies identifies three novel loci for saturated fatty acids in East Asians

Zhu, J., Manichaikul, A., Hu, Y., Chen, Y. D. I., Liang, S., Steffen, L. M., Rich, S. S., Tsai, M., Siscovick, D. S., Lemaitre, R. N., Li, H. & Lin, X., Jun 1 2017, In : European Journal of Nutrition. 56, 4, p. 1477-1484 8 p.

Research output: Contribution to journalArticle

AMP Deaminase
Genome-Wide Association Study
Meta-Analysis
Fatty Acids
Homeobox Genes
21 Citations

Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies

Wu, J. H. Y., Marklund, M., Imamura, F., Tintle, N., Ardisson Korat, A. V., de Goede, J., Zhou, X., Yang, W. S., de Oliveira Otto, M. C., Kröger, J., Qureshi, W., Virtanen, J. K., Bassett, J. K., Frazier-Wood, A. C., Lankinen, M., Murphy, R. A., Rajaobelina, K., Del Gobbo, L. C., Forouhi, N. G., Luben, R. & 31 othersKhaw, K. T., Wareham, N., Kalsbeek, A., Veenstra, J., Luo, J., Hu, F. B., Lin, H. J., Siscovick, D. S., Boeing, H., Chen, T. A., Steffen, B., Steffen, L. M., Hodge, A., Eriksdottir, G., Smith, A. V., Gudnason, V., Harris, T. B., Brouwer, I. A., Berr, C., Helmer, C., Samieri, C., Laakso, M., Tsai, M. Y., Giles, G. G., Nurmi, T., Wagenknecht, L., Schulze, M. B., Lemaitre, R. N., Chien, K. L., Soedamah-Muthu, S. S. & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE), Dec 1 2017, In : The Lancet Diabetes and Endocrinology. 5, 12, p. 965-974 10 p.

Research output: Contribution to journalArticle

Omega-6 Fatty Acids
Type 2 Diabetes Mellitus
Cohort Studies
Biomarkers
Prospective Studies
2 Citations

Residual atherosclerotic cardiovascular disease risk in statin-treated adults: The Multi-Ethnic Study of Atherosclerosis

Wong, N. D., Zhao, Y., Quek, R. G. W., Blumenthal, R. S., Budoff, M. J., Cushman, M., Garg, P., Sandfort, V., Tsai, M. & Lopez, J. A. G., Sep 1 2017, In : Journal of Clinical Lipidology. 11, 5, p. 1223-1233 11 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Atherosclerosis
Cardiovascular Diseases
Tunica Intima
LDL Lipoproteins
3 Citations

Retinol-binding protein 4 and lipids prospectively measured during early to mid-pregnancy in relation to preeclampsia and preterm birth risk

Mendola, P., Ghassabian, A., Mills, J. L., Zhang, C., Tsai, M. Y., Liu, A. & Yeung, E. H., Jan 1 2017, In : American Journal of Hypertension. 30, 6, p. 569-576 8 p.

Research output: Contribution to journalArticle

Retinol-Binding Proteins
Premature Birth
Pre-Eclampsia
Lipids
Pregnancy
1 Citations

The relationship of serum soluble receptor for advanced glycation end products (sRAGE) and carboxymethyl lysine (CML) to the incidence of diabetic nephropathy in persons with type 1 diabetes

Klein, R., Horak, K., Lee, K. E., Danforth, L., Cruickshanks, K. J., Tsai, M. Y., Gangnon, R. E. & Klein, B. E. K., Sep 1 2017, In : Diabetes care. 40, 9, p. e117-e119

Research output: Contribution to journalLetter

Diabetic Nephropathies
Type 1 Diabetes Mellitus
Incidence
Serum
N(6)-carboxymethyllysine
2016
5 Citations

ABO blood group associations with markers of endothelial dysfunction in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Bell, E. J., Decker, P. A., Pike, M., Wassel, C. L., Tsai, M. Y., Pankow, J., Tang, W., Hanson, N. Q., Alexander, K., Zakai, N. A., Cushman, M. & Bielinski, S. J., Aug 1 2016, In : Atherosclerosis. 251, p. 422-429 8 p.

Research output: Contribution to journalArticle

Selectins
Blood Group Antigens
Atherosclerosis
Alleles
von Willebrand Factor
3 Citations

Acculturation and Plasma fatty acid concentrations in Hispanic and Chinese-American adults: The Multi-Ethnic Study of Atherosclerosis

Diep, C. S., Lemaitre, R. N., Chen, T. A., Baranowski, T., Lutsey, P. L., Manichaikul, A. W., Rich, S. S., St-Jules, D. E., Steffen, B. T., Tsai, M. Y., Siscovick, D. S. & Frazier-Wood, A. C., Feb 1 2016, In : PloS one. 11, 2, e0149267.

Research output: Contribution to journalArticle

Hispanic Americans
Asian Americans
acculturation
Acculturation
atherosclerosis
7 Citations

A prospective study of erythrocyte polyunsaturated fatty acid, weight gain, and risk of becoming overweight or obese in middle-aged and older women

Wang, L., Manson, J. A. E., Rautiainen, S., Gaziano, J. M., Buring, J. E., Tsai, M. Y. & Sesso, H. D., Mar 1 2016, In : European Journal of Nutrition. 55, 2, p. 687-697 11 p.

Research output: Contribution to journalArticle

Unsaturated Fatty Acids
Weight Gain
Fatty Acids
Erythrocytes
Prospective Studies
6 Citations

Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients

Perez-Martinez, P., Alcala-Diaz, J. F., Kabagambe, E. K., Garcia-Rios, A., Tsai, M. Y., Delgado-Lista, J., Kolovou, G., Straka, R. J., Gomez-Delgado, F., Hopkins, P. N., Marin, C., Borecki, I., Yubero-Serrano, E. M., Hixson, J. E., Camargo, A., Province, M. A., Lopez-Moreno, J., Rodriguez-Cantalejo, F., Tinahones, F. J., Mikhailidis, D. P. & 4 othersPerez-Jimenez, F., Arnett, D. K., Ordovas, J. M. & Lopez-Miranda, J., Sep 1 2016, In : Journal of Clinical Lipidology. 10, 5, p. 1163-1171 9 p.

Research output: Contribution to journalArticle

Coronary Disease
Triglycerides
Population
Fats
Fasting

Blood group antigen loci demonstrate multivariate genetic associations with circulating cellular adhesion protein levels in the Multi-Ethnic Study of Atherosclerosis

Larson, N. B., Decker, P. A., Wassel, C. L., Pankow, J., Tang, W., Hanson, N. Q., Tsai, M. Y. & Bielinski, S. J., Apr 1 2016, In : Human Genetics. 135, 4, p. 415-423 9 p.

Research output: Contribution to journalArticle

Blood Group Antigens
Atherosclerosis
Proteins
Quantitative Trait Loci
Genome
6 Citations

Circulating cellular adhesion molecules and risk of diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)

Pankow, J., Decker, P. A., Berardi, C., Hanson, N. Q., Sale, M., Tang, W., Kanaya, A. M., Larson, N. B., Tsai, M. Y., Wassel, C. L. & Bielinski, S. J., Jul 1 2016, In : Diabetic Medicine. 33, 7, p. 985-991 7 p.

Research output: Contribution to journalArticle

E-Selectin
Intercellular Adhesion Molecule-1
Atherosclerosis
Vascular Cell Adhesion Molecule-1
Cadherins

Erratum: Increased levels of copeptin before clinical diagnosis of preeclampsia (Hypertension (2014) 64 (1362-1367) Doi: 10.1161/HYPERTENSIONAHA.114.03762)

Yeung, E. H., Liu, A., Mills, J. L., Zhang, C., Männistö, T., Lu, Z., Tsai, M. Y. & Mendola, P., Jul 1 2016, In : Hypertension. 68, 1, p. e4

Research output: Contribution to journalComment/debate

Pre-Eclampsia
Hypertension
copeptins
6 Citations

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

Zubair, N., Graff, M., Ambite, J. L., Bush, W. S., Kichaev, G., Lu, Y., Manichaikul, A., Sheu, W. H. H., Absher, D., Assimes, T. L., Bielinski, S. J., Bottinger, E. P., Buzkova, P., Chuang, L. M., Chung, R. H., Cochran, B., Dumitrescu, L., Gottesman, O., Haessler, J. W., Haiman, C. & 37 othersHeiss, G., Hsiung, C. A., Hung, Y. J., Hwu, C. M., Juang, J. M. J., Marchand, L. L., Lee, I. T., Lee, W. J., Lin, L. A., Lin, D., Lin, S. Y., Mackey, R. H., Martin, L. W., Pasaniuc, B., Peters, U., Predazzi, I., Quertermous, T., Reiner, A. P., Robinson, J., Rotter, J. I., Ryckman, K. K., Schreiner, P. J., Stahl, E., Tao, R., Tsai, M. Y., Waite, L. L., Wang, T. D., Buyske, S., Chen, Y. D. I., Cheng, I., Crawford, D. C., Loos, R. J. F., Rich, S. S., Fornage, M., North, K. E., Kooperberg, C. & Carty, C. L., Jan 1 2016, In : Human molecular genetics. 25, 24, p. 5500-5512 13 p.

Research output: Contribution to journalArticle

Lipids
Population
Hispanic Americans
African Americans
Asian Americans
3 Citations

Hepatocyte growth factor is positively associated with risk of stroke: The MESA (Multi-Ethnic Study of Atherosclerosis)

Bell, E. J., Larson, N. B., Decker, P. A., Pankow, J., Tsai, M. Y., Hanson, N. Q., Wassel, C. L., Longstreth, W. T. & Bielinski, S. J., Nov 1 2016, In : Stroke. 47, 11, p. 2689-2694 6 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Atherosclerosis
Stroke
Confidence Intervals
Confounding Factors (Epidemiology)
4 Citations

Impact of adiposity on cellular adhesion: The Multi-Ethnic Study of atherosclerosis (MESA)

Christoph, M. J., Allison, M. A., Pankow, J. S., Decker, P. A., Kirsch, P. S., Tsai, M. Y., Sale, M. M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Berardi, C., Wassel, C. L., Larson, N. B. & Bielinski, S. J., Jan 1 2016, In : Obesity. 24, 1, p. 223-230 8 p.

Research output: Contribution to journalArticle

Adiposity
Atherosclerosis
Intra-Abdominal Fat
Waist-Hip Ratio
Selectins
11 Citations

Insulin-like growth factor axis and gestational diabetes mellitus: A longitudinal study in a multiracial cohort

Zhu, Y., Mendola, P., Albert, P. S., Bao, W., Hinkle, S. N., Tsai, M. Y. & Zhang, C., Nov 1 2016, In : Diabetes. 65, 11, p. 3495-3504 10 p.

Research output: Contribution to journalArticle

Gestational Diabetes
Somatomedins
Longitudinal Studies
Insulin-Like Growth Factor I
Insulin-Like Growth Factor Binding Protein 3
10 Citations

Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: A meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

Ma, Y., Follis, J. L., Smith, C. E., Tanaka, T., Manichaikul, A. W., Chu, A. Y., Samieri, C., Zhou, X., Guan, W., Wang, L., Biggs, M. L., Chen, Y. D. I., Hernandez, D. G., Borecki, I., Chasman, D. I., Rich, S. S., Ferrucci, L., Irvin, M. R., Aslibekyan, S., Zhi, D. & 27 othersTiwari, H. K., Claas, S. A., Sha, J., Kabagambe, E. K., Lai, C. Q., Parnell, L. D., Lee, Y. C., Amouyel, P., Lambert, J. C., Psaty, B. M., King, I. B., Mozaffarian, D., McKnight, B., Bandinelli, S., Tsai, M. Y., Ridker, P. M., Ding, J., Mstat, K. L., Liu, Y., Sotoodehnia, N., Barberger-Gateau, P., Steffen, L. M., Siscovick, D. S., Absher, D., Arnett, D. K., Ordovás, J. M. & Lemaitre, R. N., Feb 1 2016, In : American Journal of Clinical Nutrition. 103, 2, p. 567-578 12 p.

Research output: Contribution to journalArticle

Lipid A
Eicosapentaenoic Acid
Methylation
Meta-Analysis
Epidemiology
9 Citations

Lipids, obesity and gallbladder disease in women: Insights from genetic studies using the cardiovascular gene-centric 50K SNP array

Rodriguez, S., Gaunt, T. R., Guo, Y., Zheng, J., Barnes, M. R., Tang, W., Danish, F., Johnson, A., Castillo, B. A., Li, Y. R., Hakonarson, H., Buxbaum, S. G., Palmer, T., Tsai, M. Y., Lange, L. A., Ebrahim, S., Smith, G. D., Lawlor, D. A., Folsom, A. R., Hoogeveen, R. & 3 othersReiner, A., Keating, B. & Day, I. N. M., Jan 1 2016, In : European Journal of Human Genetics. 24, 1, p. 106-112 7 p.

Research output: Contribution to journalArticle

Gallbladder Diseases
Single Nucleotide Polymorphism
Obesity
Lipids
Genes
14 Citations

Lipoprotein(a) levels are associated with subclinical calcific aortic valve disease in white and black individuals: The multi-ethnic study of atherosclerosis

Cao, J., Steffen, B. T., Budoff, M., Post, W. S., Thanassoulis, G., Kestenbaum, B., McConnell, J. P., Warnick, R., Guan, W. & Tsai, M. Y., May 1 2016, In : Arteriosclerosis, thrombosis, and vascular biology. 36, 5, p. 1003-1009 7 p.

Research output: Contribution to journalArticle

Aortic Diseases
Lipoprotein(a)
Aortic Valve
Atherosclerosis
Confidence Intervals
8 Citations

Rare copy number variants implicated in posterior urethral valves

Boghossian, N. S., Sicko, R. J., Kay, D. M., Rigler, S. L., Caggana, M., Tsai, M. Y., Yeung, E. H., Pankratz, N., Cole, B. R., Druschel, C. M., Romitti, P. A., Browne, M. L., Fan, R., Liu, A., Brody, L. C. & Mills, J. L., Mar 1 2016, In : American Journal of Medical Genetics, Part A. 170, 3, p. 622-633 12 p.

Research output: Contribution to journalArticle

Chromosomes
Gene Dosage
Population Control
Essential Genes
Live Birth
10 Citations

Sex and ethnic differences in the associations between lipoprotein(a) and peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis

Forbang, N. I., Criqui, M. H., Allison, M. A., Ix, J. H., Steffen, B. T., Cushman, M. & Tsai, M. Y., Feb 1 2016, In : Journal of Vascular Surgery. 63, 2, p. 453-458 6 p.

Research output: Contribution to journalArticle

Lipoprotein(a)
Peripheral Arterial Disease
Sex Characteristics
Atherosclerosis
African Americans
7 Citations

The effects of omega-3 polyunsaturated fatty acids and genetic variants on methylation levels of the interleukin-6 gene promoter

Ma, Y., Smith, C. E., Lai, C. Q., Irvin, M. R., Parnell, L. D., Lee, Y. C., Pham, L. D., Aslibekyan, S., Claas, S. A., Tsai, M. Y., Borecki, I. B., Kabagambe, E. K., Ordovás, J. M., Absher, D. M. & Arnett, D. K., Feb 1 2016, In : Molecular Nutrition and Food Research. 60, 2, p. 410-419 10 p.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Unsaturated Fatty Acids
interleukin-6
omega-3 fatty acids
methylation
15 Citations

Use of lipoprotein particle measures for assessing coronary heart disease risk post-American Heart Association/American College of Cardiology Guidelines: The multi-ethnic study of atherosclerosis

Steffen, B. T., Guan, W., Remaley, A. T., Paramsothy, P., Heckbert, S. R., McClelland, R. L., Greenland, P., Michos, E. D. & Tsai, M. Y., Jan 1 2016, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 448-454 7 p.

Research output: Contribution to journalArticle

Lipoproteins
Coronary Disease
Atherosclerosis
Apolipoprotein B-100
Guidelines

Vascular biomarkers to predict response to exercise in Alzheimer's disease: The study protocol

Li, D., Thomas, R. M., Tsai, M. Y., Li, L., Vock, D. M., Greimel, S. & Yu, F., Dec 1 2016, In : BMJ open. 6, 12, e011054.

Research output: Contribution to journalArticle

Cognition
Blood Vessels
Alzheimer Disease
Biomarkers
Exercise
75 Citations

ω-3 Polyunsaturated fatty acid biomarkers and coronary heart disease: Pooling project of 19 cohort studies

Del Gobbo, L. C., Imamura, F., Aslibekyan, S., Marklund, M., Virtanen, J. K., Wennberg, M., Yakoob, M. Y., Chiuve, S. E., Dela Cruz, L., Frazier-Wood, A. C., Fretts, A. M., Guallar, E., Matsumoto, C., Prem, K., Tanaka, T., Wu, J. H. Y., Zhou, X., Helmer, C., Ingelsson, E., Yuan, J. M. & 30 othersBarberger-Gateau, P., Campos, H., Chaves, P. H. M., Djoussé, L., Giles, G. G., Gómez-Aracena, J., Hodge, A. M., Hu, F. B., Jansson, J. H., Johansson, I., Khaw, K. T., Koh, W. P., Lemaitre, R. N., Lind, L., Luben, R. N., Rimm, E. B., Risérus, U., Samieri, C., Franks, P. W., Siscovick, D. S., Stampfer, M., Steffen, L. M., Steffen, B. T., Tsai, M. Y., Van Dam, R. M., Voutilainen, S., Willett, W. C., Woodward, M., Mozaffarian, D. & Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe), Aug 1 2016, In : JAMA internal medicine. 176, 8, p. 1155-1166 12 p.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Unsaturated Fatty Acids
Coronary Disease
Cohort Studies
Biomarkers
2015
2 Citations
Arachidonate 5-Lipoxygenase
Coronary Disease
Atherosclerosis
Cohort Studies
Carotid Intima-Media Thickness
2 Citations

A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet Network

Hidalgo, B., Aslibekyan, S., Wiener, H. W., Irvin, M. R., Straka, R. J., Borecki, I. B., Tiwari, H. K., Tsai, M. Y., Hopkins, P. N., Ordovas, J. M. & Arnett, D. K., Sep 23 2015, In : Pharmacogenetics and genomics. 25, 10, p. 511-514 4 p.

Research output: Contribution to journalArticle

Fenofibrate
LDL Cholesterol
Chromosomes, Human, Pair 7
Diet
Lipids
9 Citations

Carotid intima media thickness, atherosclerosis, and 5-year decline in odor identification: The beaver dam offspring study

Schubert, C. R., Cruickshanks, K. J., Fischer, M. E., Huang, G. H., Klein, R., Tsai, M. Y. & Pinto, A. A., Jan 1 2015, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 7, p. 879-884 6 p.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Rodentia
Atherosclerosis
Odds Ratio
Body Mass Index
20 Citations

Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium

Smith, C. E., Follis, J. L., Nettleton, J. A., Foy, M., Wu, J. H. Y., Ma, Y., Tanaka, T., Manichakul, A. W., Wu, H., Chu, A. Y., Steffen, L. M., Fornage, M., Mozaffarian, D., Kabagambe, E. K., Ferruci, L., Chen, Y. D. I., Rich, S. S., Djoussé, L., Ridker, P. M., Tang, W. & 16 othersMcknight, B., Tsai, M. Y., Bandinelli, S., Rotter, J. I., Hu, F. B., Chasman, D. I., Psaty, B. M., Arnett, D. K., King, I. B., Sun, Q., Wang, L., Lumley, T., Chiuve, S. E., Siscovick, D. S., Ordovás, J. M. & Lemaitre, R. N., Jan 1 2015, In : Molecular Nutrition and Food Research. 59, 7, p. 1373-1383 11 p.

Research output: Contribution to journalArticle

Erythrocyte Membrane
meta-analysis
dietary fat
Meta-Analysis
erythrocytes
49 Citations

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

Aslibekyan, S., Demerath, E. W., Mendelson, M., Zhi, D., Guan, W., Liang, L., Sha, J., Pankow, J. S., Liu, C., Irvin, M. R., Fornage, M., Hidalgo, B., Lin, L. A., Stanton Thibeault, K., Bressler, J., Tsai, M. Y., Grove, M. L., Hopkins, P. N., Boerwinkle, E., Borecki, I. B. & 5 othersOrdovas, J. M., Levy, D., Tiwari, H. K., Absher, D. M. & Arnett, D. K., Jan 1 2015, In : Obesity. 23, 7, p. 1493-1501 9 p.

Research output: Contribution to journalArticle

Waist Circumference
Methylation
Body Mass Index
Cytosine
Guanine
13 Citations

Genetic loci associated with circulating levels of very long-chain saturated fatty acids

Lemaitre, R. N., King, I. B., Kabagambe, E. K., Wu, J. H. Y., McKnight, B., Manichaikul, A., Guan, W., Sun, Q., Chasman, D. I., Foy, M., Wang, L., Zhu, J., Siscovick, D. S., Tsai, M. Y., Arnett, D. K., Psaty, B. M., Djousse, L., Chen, Y. D. I., Tang, W., Weng, L. C. & 12 othersWu, H., Jensen, M. K., Chu, A. Y., Jacobs, D. R., Rich, S. S., Mozaffarian, D., Steffen, L., Rimm, E. B., Hu, F. B., Ridker, P. M., Fornage, M. & Friedlander, Y., Jan 1 2015, In : Journal of Lipid Research. 56, 1, p. 176-184 9 p.

Research output: Contribution to journalArticle

Genetic Loci
Fatty Acids
Genes
Association reactions
Sphingolipids
14 Citations

Genetic loci associated with circulating phospholipid trans fatty acids: A meta-analysis of genome-wide association studies from the CHARGE consortium

Mozaffarian, D., Kabagambe, E. K., Johnson, C. O., Lemaitre, R. N., Manichaikul, A., Sun, Q., Foy, M., Wang, L., Wiener, H., Irvin, M. R., Rich, S. S., Wu, H., Jensen, M. K., Chasman, D. I., Chu, A. Y., Fornage, M., Steffen, L., King, I. B., McKnight, B., Psaty, B. M. & 9 othersDjoussé, L., Chen, I. Y. D., Wu, J. H. Y., Siscovick, D. S., Ridker, P. M., Tsai, M. Y., Rimm, E. B., Hu, F. B. & Arnett, D. K., Jan 1 2015, In : American Journal of Clinical Nutrition. 101, 2, p. 398-406 9 p.

Research output: Contribution to journalArticle

Trans Fatty Acids
Genetic Loci
Genome-Wide Association Study
Meta-Analysis
Phospholipids
28 Citations

Genetic variants associated with quantitative glucose homeostasis traits translate to type 2 diabetes in Mexican Americans: The GUARDIAN (Genetics underlying diabetes in Hispanics) consortium

Palmer, N. D., Goodarzi, M. O., Langefeld, C. D., Wang, N., Guo, X., Taylor, K. D., Fingerlin, T. E., Norris, J. M., Buchanan, T. A., Xiang, A. H., Haritunians, T., Ziegler, J. T., Williams, A. H., Stefanovski, D., Cui, J., Mackay, A. W., Henkin, L. F., Bergman, R. N., Gao, X., Gauderman, J. & 29 othersVarma, R., Hanis, C. L., Cox, N. J., Highland, H. M., Below, J. E., Williams, A. L., Burtt, N. P., Aguilar-Salinas, C. A., Huerta-Chagoya, A., Gonzalez-Villalpando, C., Orozco, L., Haiman, C. A., Tsai, M. Y., Johnson, W. C., Yao, J., Rasmussen-Torvik, L., Pankow, J., Snively, B., Jackson, R. D., Liu, S., Nadler, J. L., Kandeel, F., Chen, Y. D. I., Bowden, D. W., Rich, S. S., Raffel, L. J., Rotter, J. I., Watanabe, R. M. & Wagenknecht, L. E., May 1 2015, In : Diabetes. 64, 5, p. 1853-1866 14 p.

Research output: Contribution to journalArticle

Hispanic Americans
Type 2 Diabetes Mellitus
Homeostasis
Glucose
Insulin
17 Citations

Genetic variants modify the effect of age on APOE methylation in the genetics of lipid lowering drugs and diet network study

Ma, Y., Smith, C. E., Lai, C. Q., Irvin, M. R., Parnell, L. D., Lee, Y. C., Pham, L., Aslibekyan, S., Claas, S. A., Tsai, M. Y., Borecki, I. B., Kabagambe, E. K., Berciano, S., Ordovás, J. M., Absher, D. M. & Arnett, D. K., Jan 1 2015, In : Aging cell. 14, 1, p. 49-59 11 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Methylation
Diet
Lipids
Pharmaceutical Preparations
14 Citations

Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in chinese and european-ancestry populations

Hu, Y., Li, H., Lu, L., Manichaikul, A., Zhu, J., Chen, I. Y. D., Sun, L., Liang, S., Siscovick, D. S., Steffen, L. M., Tsai, M. Y., Rich, S. S., Lemaitre, R. N. & Lin, X., Aug 17 2015, In : Human molecular genetics. 25, 6, p. 1215-1224 10 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Unsaturated Fatty Acids
Meta-Analysis
Genome
Population
246 Citations

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials

Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J. & 113 othersHoward, P., Cooper, J. A., Drenos, F., Li, Y. R., Lowe, G., Gallacher, J., Stewart, M. C. W., Tzoulaki, I., Buxbaum, S. G., Van Der A, D. L., Forouhi, N. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Schnabel, R. B., Hubacek, J. A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S., Baldassarre, D., Sennblad, B., Tremoli, E., De Faire, U., Veglia, F., Ford, I., Jukema, J. W., Westendorp, R. G. J., De Borst, G. J., De Jong, P. A., Algra, A., Spiering, W., Der Zee, A. H. M. V., Klungel, O. H., De Boer, A., Doevendans, P. A., Eaton, C. B., Robinson, J. G., Duggan, D., Kjekshus, J., Downs, J. R., Gotto, A. M., Keech, A. C., Marchioli, R., Tognoni, G., Sever, P. S., Poulter, N. R., Waters, D. D., Pedersen, T. R., Amarenco, P., Nakamura, H., McMurray, J. J. V., Lewsey, J. D., Chasman, D. I., Ridker, P. M., Maggioni, A. P., Tavazzi, L., Ray, K. K., Seshasai, S. R. K., Manson, J. E., Price, J. F., Whincup, P. H., Morris, R. W., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Schreiner, P. J., Fornage, M., Siscovick, D. S., Cushman, M., Kumari, M., Wareham, N. J., Verschuren, W. M. M., Redline, S., Patel, S. R., Whittaker, J. C., Hamsten, A., Delaney, J. A., Dale, C., Gaunt, T. R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B. A., Van Der Harst, P., Brunner, E. J., Tybjaerg-Hansen, A., Marmot, M. G., Krauss, R. M., Tsai, M., Coresh, J., Hoogeveen, R. C., Psaty, B. M., Lange, L. A., Hakonarson, H., Dudbridge, F., Humphries, S. E., Talmud, P. J., Kivimäki, M., Timpson, N. J., Langenberg, C., Asselbergs, F. W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J. G., Reiner, A. P., Keating, B. J., Hingorani, A. D. & Sattar, N., Jan 1 2015, In : The Lancet. 385, 9965, p. 351-361 11 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Coenzyme A
Type 2 Diabetes Mellitus
Oxidoreductases
Alleles
157 Citations

Mendelian randomization of blood lipids for coronary heart disease

Holmes, M. V., Asselbergs, F. W., Palmer, T. M., Drenos, F., Lanktree, M. B., Nelson, C. P., Dale, C. E., Padmanabhan, S., Finan, C., Swerdlow, D. I., Tragante, V., Van Iperen, E. P. A., Sivapalaratnam, S., Shah, S., Elbers, C. C., Shah, T., Engmann, J., Giambartolomei, C., White, J., Zabaneh, D. & 48 othersSofat, R., McLachlan, S., Doevendans, P. A., Balmforth, A. J., Hall, A. S., North, K. E., Almoguera, B., Hoogeveen, R. C., Cushman, M., Fornage, M., Patel, S. R., Redline, S., Siscovick, D. S., Tsai, M. Y., Karczewski, K. J., Hofker, M. H., Verschuren, W. M., Bots, M. L., Van Der Schouw, Y. T., Melander, O., Dominiczak, A. F., Morris, R., Ben-Shlomo, Y., Price, J., Kumari, M., Baumert, J., Peters, A., Thorand, B., Koenig, W., Gaunt, T. R., Humphries, S. E., Clarke, R., Watkins, H., Farrall, M., Wilson, J. G., Rich, S. S., De Bakker, P. I. W., Lange, L. A., Smith, G. D., Reiner, A. P., Talmud, P. J., Kivimäki, M., Lawlor, D. A., Dudbridge, F., Samani, N. J., Keating, B. J., Hingorani, A. D. & Casas, J. P., Jan 1 2015, In : European Heart Journal. 36, 9, p. 539-550 12 p.

Research output: Contribution to journalArticle

Random Allocation
Single Nucleotide Polymorphism
Coronary Disease
HDL Cholesterol
Lipids