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  • Michael Y Tsai

Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium

Smith, C. E., Follis, J. L., Nettleton, J. A., Foy, M., Wu, J. H. Y., Ma, Y., Tanaka, T., Manichakul, A. W., Wu, H., Chu, A. Y., Steffen, L. M., Fornage, M., Mozaffarian, D., Kabagambe, E. K., Ferruci, L., Chen, Y. D. I., Rich, S. S., Djoussé, L., Ridker, P. M., Tang, W. & 16 others, Mcknight, B., Tsai, M. Y., Bandinelli, S., Rotter, J. I., Hu, F. B., Chasman, D. I., Psaty, B. M., Arnett, D. K., King, I. B., Sun, Q., Wang, L., Lumley, T., Chiuve, S. E., Siscovick, D. S., Ordovás, J. M. & Lemaitre, R. N., Jul 1 2015, In : Molecular Nutrition and Food Research. 59, 7, p. 1373-1383 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations

Hu, Y., Tanaka, T., Zhu, J., Guan, W., Wu, J. H. Y., Psaty, B. M., McKnight, B., King, I. B., Sun, Q., Richard, M., Manichaikul, A., Frazier-Wood, A. C., Kabagambe, E. K., Hopkins, P. N., Ordovas, J. M., Ferrucci, L., Bandinelli, S., Arnett, D. K., Chen, Y. D. I., Liang, S. & 13 others, Siscovick, D. S., Tsai, M. Y., Rich, S. S., Fornage, M., Hu, F. B., Rimm, E. B., Jensen, M. K., Lemaitre, R. N., Mozaffarian, D., Steffen, L. M., Morris, A. P., Li, H. & Lin, X., May 2017, In : Journal of lipid research. 58, 5, p. 974-981 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Effects of fenofibrate on plasma oxidized LDL and 8-isoprostane in a sub-cohort of GOLDN participants

Dong, Y., Steffen, B. T., Cao, J., Tsai, A. K., Ordovas, J., Straka, R., Zhou, X., Kabagambe, E., Hanson, N. Q., Arnett, D. & Tsai, M. Y., Feb 1 2011, In : Atherosclerosis. 214, 2, p. 422-425 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Elevated Levels of Adhesion Proteins Are Associated with Low Ankle-Brachial Index: Multi-Ethnic Study of Atherosclerosis

Berardi, C., Wassel, C. L., Decker, P. A., Larson, N. B., Kirsch, P. S., Andrade, M. D., Tsai, M. Y., Pankow, J. S., Sale, M. M., Sicotte, H., Tang, W., Hanson, N. Q., McDermott, M. M., Criqui, M. H., Allison, M. A. & Bielinski, S. J., Apr 1 2017, In : Angiology. 68, 4, p. 322-329 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

Aslibekyan, S., Demerath, E. W., Mendelson, M., Zhi, D., Guan, W., Liang, L., Sha, J., Pankow, J. S., Liu, C., Irvin, M. R., Fornage, M., Hidalgo, B., Lin, L. A., Stanton Thibeault, K., Bressler, J., Tsai, M. Y., Grove, M. L., Hopkins, P. N., Boerwinkle, E., Borecki, I. B. & 5 others, Ordovas, J. M., Levy, D., Tiwari, H. K., Absher, D. M. & Arnett, D. K., Jul 1 2015, In : Obesity. 23, 7, p. 1493-1501 9 p.

Research output: Contribution to journalArticle

82 Scopus citations

Epistatic study reveals two genetic interactions in blood pressure regulation

Ndiaye, N. C., Said, E. S., Stathopoulou, M. G., Siest, G., Tsai, M. Y. & Visvikis-Siest, S., Jan 8 2013, In : BMC medical genetics. 14, 1, 2.

Research output: Contribution to journalArticle

9 Scopus citations

Erratum: Increased levels of copeptin before clinical diagnosis of preeclampsia (Hypertension (2014) 64 (1362-1367) Doi: 10.1161/HYPERTENSIONAHA.114.03762)

Yeung, E. H., Liu, A., Mills, J. L., Zhang, C., Männistö, T., Lu, Z., Tsai, M. Y. & Mendola, P., Jul 1 2016, In : Hypertension. 68, 1, p. e4

Research output: Contribution to journalComment/debate

Erratum: Causal effects of body mass index on cardiometabolic traits and events: A mendelian randomization analysis (American Journal of Human Genetics (2014) 94 (198-208))

Holmes, M. V., Lange, L. A., Palmer, T., Lanktree, M. B., North, K. E., Almoguera, B., Buxbaum, S., Chandrupatla, H. R., Elbers, C. C., Guo, Y., Hoogeveen, R. C., Li, J., Li, Y. R., Swerdlow, D. I., Cushman, M., Price, T. S., Curtis, S. P., Fornage, M., Hakonarson, H., Patel, S. R. & 14 others, Redline, S., Siscovick, D. S., Tsai, M. Y., Wilson, J. G., Van Der Schouw, Y. T., Fitzgerald, G. A., Hingorani, A. D., Casas, J. P., De Bakker, P. I. W., Rich, S. S., Schadt, E. E., Asselbergs, F. W., Reiner, A. P. & Keating, B. J., Feb 6 2014, In : American Journal of Human Genetics. 94, 2, p. 312 1 p.

Research output: Contribution to journalComment/debate

Open Access

Erythrocyte fatty acid composition is associated with the risk of hypertension in middle-aged and older women

Wang, L., Tsai, M. Y., Manson, J. A. E., Djousse, L., Gaziano, J. M., Buring, J. E. & Sesso, H. D., Sep 1 2011, In : Journal of Nutrition. 141, 9, p. 1691-1697 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Ethnicity, plasma phospholipid fatty acid composition and inflammatory/endothelial activation biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA)

Steffen, B. T., Steffen, L. M., Tracy, R., Siscovick, D., Jacobs, D., Liu, K., He, K., Hanson, N. Q., Nettleton, J. A. & Tsai, M. Y., May 2012, In : European Journal of Clinical Nutrition. 66, 5, p. 600-605 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Evaluating the Potential Association Between Lipoprotein(a) and Atherosclerosis (from the Mediators of Atherosclerosis Among South Asians Living in America Cohort)

Huffman, M. D., Kandula, N. R., Baldridge, A. S., Tsai, M. Y., Prabhakaran, D. & Kanaya, A. M., Mar 15 2019, In : American Journal of Cardiology. 123, 6, p. 919-921 3 p.

Research output: Contribution to journalArticle

Open Access
Open Access
11 Scopus citations

Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

InterAct Consortium & Fatty Acids and Outcomes Research Consortium (FORCE), Oct 2018, In : PLoS Medicine. 15, 10, e1002670.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

InterAct Consortium, Jun 2020, In : PLoS Medicine. 17, 6, e1003102.

Research output: Contribution to journalArticle

Open Access

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

Zubair, N., Graff, M., Ambite, J. L., Bush, W. S., Kichaev, G., Lu, Y., Manichaikul, A., Sheu, W. H. H., Absher, D., Assimes, T. L., Bielinski, S. J., Bottinger, E. P., Buzkova, P., Chuang, L. M., Chung, R. H., Cochran, B., Dumitrescu, L., Gottesman, O., Haessler, J. W., Haiman, C. & 37 others, Heiss, G., Hsiung, C. A., Hung, Y. J., Hwu, C. M., Juang, J. M. J., Marchand, L. L., Lee, I. T., Lee, W. J., Lin, L. A., Lin, D., Lin, S. Y., Mackey, R. H., Martin, L. W., Pasaniuc, B., Peters, U., Predazzi, I., Quertermous, T., Reiner, A. P., Robinson, J., Rotter, J. I., Ryckman, K. K., Schreiner, P. J., Stahl, E., Tao, R., Tsai, M. Y., Waite, L. L., Wang, T. D., Buyske, S., Chen, Y. D. I., Cheng, I., Crawford, D. C., Loos, R. J. F., Rich, S. S., Fornage, M., North, K. E., Kooperberg, C. & Carty, C. L., 2016, In : Human molecular genetics. 25, 24, p. 5500-5512 13 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Free fatty acids, cardiovascular disease, and mortality in the Multi-Ethnic Study of Atherosclerosis

Nomura, S. O., Karger, A. B., Weir, N. L., Duprez, D. A. & Tsai, M. Y., Jul 1 2020, In : Journal of Clinical Lipidology. 14, 4, p. 531-541 11 p.

Research output: Contribution to journalArticle

Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals

Guo, Y., Lanktree, M. B., Taylor, K. C., Hakonarson, H., Lange, L. A., Keating, B. J., Guo, Y., Lanktree, M. B., Taylor, K. C., Fairfax, B. P., Elbers, C. C., Barnard, J., Farrall, M., Padmanabhan, S., Baumert, J., Castillo, B. A., Gaunt, T. R., Gong, Y., Rajagopalan, R., Romaine, S. P. R. & 184 others, Kumari, M., Rafelt, S., Smith, E. N., Li, Y. R., Sivapalaratnam, S., van Iperen, E. P. A., Speliotes, E. K., Toskala, E., Zhang, L., Ochs-Balcom, H. M., Bhangale, T. R., Chandrupatla, H. R., Drenos, F., Gieger, C., Gupta, J., Johnson, T., Kleber, M. E., Makino, S., Mangino, M., Meng, Y., Nelson, C. P., Pankow, J. S., Pankratz, N., Price, T. S., Shaffer, J., Shen, H., Tischfield, S., Tomaszewski, M., Atwood, L. D., Bailey, K. M., Balasubramanyam, A., Baldwin, C. T., Basart, H., Bauer, F., Behr, E. R., Beitelshees, A. L., Berenson, G. S., Beresford, S. A. A., Bezzina, C. R., Bhatt, D. L., Boer, J. M. A., Braund, P. S., Burke, G. L., Burkley, B., Carty, C., Chen, W., Clarke, R., Cooper-DeHoff, R. M., Curtis, S. P., de Bakker, P. I. W., de Jong, J. S., Delles, C., Dominiczak, A. F., Duggan, D., Feldman, H. I., Furlong, C. E., Gorski, M. M., Gums, J. G., Hardwick, R., Hastie, C., Heid, I. M., Huang, G. H., Huggins, G. S., Humphries, S. E., Kirkland, S. A., Kivimaki, M., Klein, R., Klein, B. E., Knowler, W. C., Kandice Kottke-Marchant, K-M., LaCroix, A. Z., Langaee, T. Y., Li, M., Lyon, H. N., Maiwald, S., Marshall, J. K., Mehta, A., Meijs, M. F. L., Melander, O., Meyer, N., Mitra, N., Molony, C. M., Morrow, D. A., Murugesan, G., Newhouse, S. J., Nieto, J. F., Onland-Moret, N. C., Ouwehand, W. H., Palmen, J., Pepine, C. J., Ranchalis, J., Rosas, S. E., Rosenthal, E. A., Scharnagl, H., Schork, N. J., Schreiner, P. J., Shah, T., Shashaty, M., Shimbo, D., Srinivasan, S. R., Thomas, F., Tobin, M. D., Tsai, M. Y., Monique Verschuren, W. M., Wagenknecht, L. E., Winkelmann, B. R., Young, T., Yusuf, S., Zafarmand, M. H., Zmuda, J. M., Zwinderman, A. H., Anand, S. S., Balmforth, A. J., Boehm, B. O., Boerwinkle, E., Burton, P. R., Cappola, T. P., Casas, J. P., Caulfield, M. J., Christiani, D. C., Christie, J., Cruickshanks, K. J., Davey-Smith, G., Davidson, K. W., Day, I. N., Doevendans, P. A., Dorn, G. W., FitzGerald, G. A., Hall, A. S., Hingorani, A. D., Hirschhorn, J. N., Hofker, M. H., Hovingh, K. G., Illig, T., Jamshidi, Y., Jarvik, G. P., Johnson, J. A., Kanetsky, P. A., John JP Kastelein, JP. K., Koenig, W., Lawlor, D. A., März, W., McCaffery, J., Mega, J. L., Mitchell, B. D., Murray, S. S., O'Connell, J. R., Patel, S. R., Peters, A., Pettinger, M., Rader, D. J., Redline, S., Reilly, M. P., Sabatine, M. S., Schadt, E. E., Shuldiner, A. R., Silverstein, R. L., Spector, T. D., Taylor, H. A., Thorand, B., Trip, M. D., Watkins, H., Wichmann, H. E., Fox, C. S., Grant, S. F. A., Peter, I., Talmud, P. J., Munroe, P. B., Wilson, J. G., Knight, J. C., Samani, N. J., Hegele, R. A., Asselbergs, F. W., Monda, K. L., van der Schouw, Y. T., Demerath, E. W., Wijmenga, C., Timpson, N. J., Reiner, A. P., North, K. E., Papanicolaou, G. J., Hakonarson, H., Lange, L. A. & Keating, B. J., Jan 2013, In : Human molecular genetics. 22, 1, p. 184-201 18 p., dds396.

Research output: Contribution to journalArticle

57 Scopus citations

Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations

Elbers, C. C., Guo, Y., Tragante, V., van Iperen, E. P. A., Lanktree, M. B., Castillo, B. A., Chen, F., Yanek, L. R., Wojczynski, M. K., Li, Y. R., Ferwerda, B., Ballantyne, C. M., Buxbaum, S. G., Chen, Y. D. I., Chen, W. M., Cupples, L. A., Cushman, M., Duan, Y., Duggan, D., Evans, M. K. & 50 others, Fernandes, J. K., Fornage, M., Garcia, M., Garvey, W. T., Glazer, N., Gomez, F., Harris, T. B., Halder, I., Howard, V. J., Keller, M. F., Kamboh, M. I., Kooperberg, C., Kritchevsky, S. B., LaCroix, A., Liu, K., Liu, Y., Musunuru, K., Newman, A. B., Onland-Moret, N. C., Ordovas, J., Peter, I., Post, W., Redline, S., Reis, S. E., Saxena, R., Schreiner, P. J., Volcik, K. A., Wang, X., Yusuf, S., Zonderland, A. B., Anand, S. S., Becker, D. M., Psaty, B., Rader, D. J., Reiner, A. P., Rich, S. S., Rotter, J. I., Sale, M. M., Tsai, M. Y., Borecki, I. B., Hegele, R. A., Kathiresan, S., Nalls, M. A., Taylor, H. A., Hakonarson, H., Sivapalaratnam, S., Asselbergs, F. W., Drenos, F., Wilson, J. G. & Keating, B. J., Dec 7 2012, In : PloS one. 7, 12, e50198.

Research output: Contribution to journalArticle

28 Scopus citations

Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study

Kraja, A. T., Borecki, I. B., Tsai, M. Y., Ordovas, J. M., Hopkins, P. N., Lai, C. Q., Frazier-Wood, A. C., Straka, R. J., Hixson, J. E., Province, M. A. & Arnett, D. K., Feb 2013, In : Lipids. 48, 2, p. 155-165 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Genetic associations with lipoprotein subfraction measures differ by ethnicity in the multi-ethnic study of atherosclerosis (MESA)

Wang, Z., Manichukal, A., Goff, D. C., Mora, S., Ordovas, J. M., Pajewski, N. M., Post, W. S., Rotter, J. I., Sale, M. M., Santorico, S. A., Siscovick, D., Tsai, M. Y., Arnett, D. K., Rich, S. & Frazier-Wood, A. C., Jun 1 2017, In : Human Genetics. 136, 6, p. 715-726 12 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Genetic loci associated with circulating levels of very long-chain saturated fatty acids

Lemaitre, R. N., King, I. B., Kabagambe, E. K., Wu, J. H. Y., McKnight, B., Manichaikul, A., Guan, W., Sun, Q., Chasman, D. I., Foy, M., Wang, L., Zhu, J., Siscovick, D. S., Tsai, M. Y., Arnett, D. K., Psaty, B. M., Djousse, L., Chen, Y. D. I., Tang, W., Weng, L. C. & 12 others, Wu, H., Jensen, M. K., Chu, A. Y., Jacobs, D. R., Rich, S. S., Mozaffarian, D., Steffen, L., Rimm, E. B., Hu, F. B., Ridker, P. M., Fornage, M. & Friedlander, Y., Jan 1 2015, In : Journal of lipid research. 56, 1, p. 176-184 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genetic loci associated with circulating phospholipid trans fatty acids: A meta-analysis of genome-wide association studies from the CHARGE consortium

Mozaffarian, D., Kabagambe, E. K., Johnson, C. O., Lemaitre, R. N., Manichaikul, A., Sun, Q., Foy, M., Wang, L., Wiener, H., Irvin, M. R., Rich, S. S., Wu, H., Jensen, M. K., Chasman, D. I., Chu, A. Y., Fornage, M., Steffen, L., King, I. B., McKnight, B., Psaty, B. M. & 9 others, Djoussé, L., Chen, I. Y. D., Wu, J. H. Y., Siscovick, D. S., Ridker, P. M., Tsai, M. Y., Rimm, E. B., Hu, F. B. & Arnett, D. K., Feb 1 2015, In : American Journal of Clinical Nutrition. 101, 2, p. 398-406 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Genetic loci associated with plasma phospholipid N-3 fatty acids: A Meta-Analysis of Genome-Wide association studies from the charge consortium

Lemaitre, R. N., Tanaka, T., Tang, W., Manichaikul, A., Foy, M., Kabagambe, E. K., Nettleton, J. A., King, I. B., Weng, L. C., Bhattacharya, S., Bandinelli, S., Bis, J. C., Rich, S. S., Jacobs, D. R., Cherubini, A., McKnight, B., Liang, S., Gu, X., Rice, K., Laurie, C. C. & 15 others, Lumley, T., Browning, B. L., Psaty, B. M., Chen, Y. D. I., Friedlander, Y., Djousse, L., Wu, J. H. Y., Siscovick, D. S., Uitterlinden, A. G., Arnett, D. K., Ferrucci, L., Fornage, M., Tsai, M. Y., Mozaffarian, D. & Steffen, L. M., Jul 2011, In : PLoS genetics. 7, 7, e1002193.

Research output: Contribution to journalArticle

205 Scopus citations

Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrate

Frazier-Wood, A. C., Wojczynski, M. K., Borecki, I. B., Hopkins, P. N., Lai, C. Q., Ordovas, J. M., Straka, R. J., Tsai, M. Y., Tiwari, H. K. & Arnett, D. K., Aug 25 2014, In : Biology. 3, 3, p. 536-550 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genetic variants associated with quantitative glucose homeostasis traits translate to type 2 diabetes in Mexican Americans: The GUARDIAN (Genetics underlying diabetes in Hispanics) consortium

Palmer, N. D., Goodarzi, M. O., Langefeld, C. D., Wang, N., Guo, X., Taylor, K. D., Fingerlin, T. E., Norris, J. M., Buchanan, T. A., Xiang, A. H., Haritunians, T., Ziegler, J. T., Williams, A. H., Stefanovski, D., Cui, J., Mackay, A. W., Henkin, L. F., Bergman, R. N., Gao, X., Gauderman, J. & 29 others, Varma, R., Hanis, C. L., Cox, N. J., Highland, H. M., Below, J. E., Williams, A. L., Burtt, N. P., Aguilar-Salinas, C. A., Huerta-Chagoya, A., Gonzalez-Villalpando, C., Orozco, L., Haiman, C. A., Tsai, M. Y., Johnson, W. C., Yao, J., Rasmussen-Torvik, L., Pankow, J., Snively, B., Jackson, R. D., Liu, S., Nadler, J. L., Kandeel, F., Chen, Y. D. I., Bowden, D. W., Rich, S. S., Raffel, L. J., Rotter, J. I., Watanabe, R. M. & Wagenknecht, L. E., May 2015, In : Diabetes. 64, 5, p. 1853-1866 14 p.

Research output: Contribution to journalArticle

45 Scopus citations

Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity

Frazier-Wood, A. C., Manichaikul, A., Aslibekyan, S., Borecki, I. B., Goff, D. C., Hopkins, P. N., Lai, C. Q., Ordovas, J. M., Post, W. S., Rich, S. S., Sale, M. M., Siscovick, D., Straka, R. J., Tiwari, H. K., Tsai, M. Y., Rotter, J. I. & Arnett, D. K., Apr 1 2013, In : Human Genetics. 132, 4, p. 405-413 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Genetic variants modify the effect of age on APOE methylation in the genetics of lipid lowering drugs and diet network study

Ma, Y., Smith, C. E., Lai, C. Q., Irvin, M. R., Parnell, L. D., Lee, Y. C., Pham, L., Aslibekyan, S., Claas, S. A., Tsai, M. Y., Borecki, I. B., Kabagambe, E. K., Berciano, S., Ordovás, J. M., Absher, D. M. & Arnett, D. K., Feb 1 2015, In : Aging cell. 14, 1, p. 49-59 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium

De Oliveira Otto, M. C., Lemaitre, R. N., Sun, Q., King, I. B., Wu, J. H. Y., Manichaikul, A., Rich, S. S., Tsai, M. Y., Chen, Y. D., Fornage, M., Weihua, G., Aslibekyan, S., Irvin, M. R., Kabagambe, E. K., Arnett, D. K., Jensen, M. K., McKnight, B., Psaty, B. M., Steffen, L. M., Smith, C. E. & 6 others, Risérus, U., Lind, L., Hu, F. B., Rimm, E. B., Siscovick, D. S. & Mozaffarian, D., May 2018, In : PloS one. 13, 5, e0196951.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts

Mozaffarian, D., Dashti, H. S., Wojczynski, M. K., Chu, A. Y., Nettleton, J. A., Männistö, S., Kristiansson, K., Reedik, M., Lahti, J., Houston, D. K., Cornelis, M. C., Van Rooij, F. J. A., Dimitriou, M., Kanoni, S., Mikkilä, V., Steffen, L. M., De Oliveira Otto, M. C., Qi, L., Psaty, B., Djousse, L. & 45 others, Rotter, J. I., Harald, K., Perola, M., Rissanen, H., Jula, A., Krista, F., Mihailov, E., Feitosa, M. F., Ngwa, J. S., Xue, L., Jacques, P. F., Perälä, M. M., Palotie, A., Liu, Y., Nalls, N. A., Ferrucci, L., Hernandez, D., Manichaikul, A., Tsai, M. Y., Kiefte-De Jong, J. C., Hofman, A., Uitterlinden, A. G., Rallidis, L., Ridker, P. M., Rose, L. M., Buring, J. E., Lehtimäki, T., Kähönen, M., Viikari, J., Lemaitre, R., Salomaa, V., Knekt, P., Metspalu, A., Borecki, I. B., Cupples, L. A., Eriksson, J. G., Kritchevsky, S. B., Bandinelli, S., Siscovick, D., Franco, O. H., Deloukas, P., Dedoussis, G., Chasman, D. I., Raitakari, O. & Tanaka, T., Dec 2017, In : PloS one. 12, 12, e0186456.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response

An, P., Straka, R. J., Pollin, T. I., Feitosa, M. F., Wojczynski, M. K., Daw, E. W., O'Connell, J. R., Gibson, Q., Ryan, K. A., Hopkins, P. N., Tsai, M. Y., Lai, C. Q., Province, M. A., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Jul 2014, In : Human Genetics. 133, 7, p. 919-930 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: Results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

Wu, J. H. Y., Lemaitre, R. N., Manichaikul, A., Guan, W., Tanaka, T., Foy, M., Kabagambe, E. K., Djousse, L., Siscovick, D., Fretts, A. M., Johnson, C., King, I. B., Psaty, B. M., McKnight, B., Rich, S. S., Chen, Y. D. I., Nettleton, J. A., Tang, W., Bandinelli, S., Jacobs, D. R. & 8 others, Browning, B. L., Laurie, C. C., Gu, X., Tsai, M. Y., Steffen, L. M., Ferrucci, L., Fornage, M. & Mozaffarian, D., Apr 2013, In : Circulation: Cardiovascular Genetics. 6, 2, p. 171-183 13 p.

Research output: Contribution to journalArticle

51 Scopus citations

Genome-Wide association study of plasma n6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium

Guan, W., Steffen, B. T., Lemaitre, R. N., Wu, J. H. Y., Tanaka, T., Manichaikul, A., Foy, M., Rich, S. S., Wang, L., Nettleton, J. A., Tang, W., Gu, X., Bandinelli, S., King, I. B., McKnight, B., Psaty, B. M., Siscovick, D., Djousse, L., Chen, Y. D. I., Ferrucci, L. & 4 others, Fornage, M., Mozafarrian, D., Tsai, M. Y. & Steffen, L. M., Jun 2014, In : Circulation: Cardiovascular Genetics. 7, 3, p. 321-331 11 p.

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69 Scopus citations

Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in chinese and european-ancestry populations

Hu, Y., Li, H., Lu, L., Manichaikul, A., Zhu, J., Chen, I. Y. D., Sun, L., Liang, S., Siscovick, D. S., Steffen, L. M., Tsai, M. Y., Rich, S. S., Lemaitre, R. N. & Lin, X., Aug 17 2015, In : Human molecular genetics. 25, 6, p. 1215-1224 10 p.

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21 Scopus citations

Gestational diabetes mellitus and renal function: A prospective study with 9-to 16-year follow-up after pregnancy

Rawal, S., Olsen, S. F., Grunnet, L. G., Ma, R. C., Hinkle, S. N., Granström, C., Wu, J., Yeung, E., Mills, J. L., Zhu, Y., Bao, W., Ley, S. H., Hu, F. B., Damm, P., Vaag, A., Tsai, M. Y. & Zhang, C., Jul 1 2018, In : Diabetes care. 41, 7, p. 1378-1384 7 p.

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6 Scopus citations

HbA1c Measured in the First Trimester of Pregnancy and the Association with Gestational Diabetes

Hinkle, S. N., Tsai, M. Y., Rawal, S., Albert, P. S. & Zhang, C., Dec 1 2018, In : Scientific reports. 8, 1, 12249.

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9 Scopus citations

Hepatocyte growth factor demonstrates racial heterogeneity as a biomarker for coronary heart disease

Bielinski, S. J., Berardi, C., Decker, P. A., Larson, N. B., Bell, E. J., Pankow, J. S., Sale, M. M., Tang, W., Hanson, N. Q., Wassel, C. L., De Andrade, M., Budoff, M. J., Polak, J. F., Sicotte, H. & Tsai, M. Y., Aug 1 2017, In : Heart. 103, 15, p. 1185-1193 9 p.

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5 Scopus citations

Hepatocyte growth factor is associated with progression of atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA)

Bell, E. J., Decker, P. A., Tsai, M. Y., Pankow, J. S., Hanson, N. Q., Wassel, C. L., Larson, N. B., Cohoon, K. P., Budoff, M. J., Polak, J. F., Stein, J. H. & Bielinski, S. J., May 2018, In : Atherosclerosis. 272, p. 162-167 6 p.

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3 Scopus citations

Hepatocyte growth factor is positively associated with risk of stroke: The MESA (Multi-Ethnic Study of Atherosclerosis)

Bell, E. J., Larson, N. B., Decker, P. A., Pankow, J. S., Tsai, M. Y., Hanson, N. Q., Wassel, C. L., Longstreth, W. T. & Bielinski, S. J., Nov 1 2016, In : Stroke. 47, 11, p. 2689-2694 6 p.

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7 Scopus citations

High-Density Lipoprotein Subspecies Defined by Presence of Apolipoprotein C-III and Incident Coronary Heart Disease in Four Cohorts

Jensen, M. K., Aroner, S. A., Mukamal, K. J., Furtado, J. D., Post, W. S., Tsai, M. Y., Tjønneland, A., Polak, J. F., Rimm, E. B., Overvad, K., McClelland, R. L. & Sacks, F. M., Mar 27 2018, In : Circulation. 137, 13, p. 1364-1373 10 p.

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Open Access
24 Scopus citations

High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering drugs and diet network (GOLDN): An interventional study

Wojczynski, M. K., Glasser, S. P., Oberman, A., Kabagambe, E. K., Hopkins, P. N., Tsai, M. Y., Straka, R. J., Ordovas, J. M. & Arnett, D. K., 2011, In : Lipids in Health and Disease. 10, 181.

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38 Scopus citations

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials

Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J. & 113 others, Howard, P., Cooper, J. A., Drenos, F., Li, Y. R., Lowe, G., Gallacher, J., Stewart, M. C. W., Tzoulaki, I., Buxbaum, S. G., Van Der A, D. L., Forouhi, N. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Schnabel, R. B., Hubacek, J. A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S., Baldassarre, D., Sennblad, B., Tremoli, E., De Faire, U., Veglia, F., Ford, I., Jukema, J. W., Westendorp, R. G. J., De Borst, G. J., De Jong, P. A., Algra, A., Spiering, W., Der Zee, A. H. M. V., Klungel, O. H., De Boer, A., Doevendans, P. A., Eaton, C. B., Robinson, J. G., Duggan, D., Kjekshus, J., Downs, J. R., Gotto, A. M., Keech, A. C., Marchioli, R., Tognoni, G., Sever, P. S., Poulter, N. R., Waters, D. D., Pedersen, T. R., Amarenco, P., Nakamura, H., McMurray, J. J. V., Lewsey, J. D., Chasman, D. I., Ridker, P. M., Maggioni, A. P., Tavazzi, L., Ray, K. K., Seshasai, S. R. K., Manson, J. E., Price, J. F., Whincup, P. H., Morris, R. W., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Schreiner, P. J., Fornage, M., Siscovick, D. S., Cushman, M., Kumari, M., Wareham, N. J., Verschuren, W. M. M., Redline, S., Patel, S. R., Whittaker, J. C., Hamsten, A., Delaney, J. A., Dale, C., Gaunt, T. R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B. A., Van Der Harst, P., Brunner, E. J., Tybjaerg-Hansen, A., Marmot, M. G., Krauss, R. M., Tsai, M., Coresh, J., Hoogeveen, R. C., Psaty, B. M., Lange, L. A., Hakonarson, H., Dudbridge, F., Humphries, S. E., Talmud, P. J., Kivimäki, M., Timpson, N. J., Langenberg, C., Asselbergs, F. W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J. G., Reiner, A. P., Keating, B. J., Hingorani, A. D. & Sattar, N., Jan 24 2015, In : The Lancet. 385, 9965, p. 351-361 11 p.

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331 Scopus citations

Impact of adiposity on cellular adhesion: The Multi-Ethnic Study of atherosclerosis (MESA)

Christoph, M. J., Allison, M. A., Pankow, J. S., Decker, P. A., Kirsch, P. S., Tsai, M. Y., Sale, M. M., De Andrade, M., Sicotte, H., Tang, W., Hanson, N. Q., Berardi, C., Wassel, C. L., Larson, N. B. & Bielinski, S. J., Jan 1 2016, In : Obesity. 24, 1, p. 223-230 8 p.

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7 Scopus citations

Increased hepatocyte growth factor levels over 2 years are associated with coronary heart disease: the Multi-Ethnic Study of Atherosclerosis (MESA)

Decker, P. A., Larson, N. B., Bell, E. J., Pankow, J. S., Hanson, N. Q., Wassel, C. L., Tsai, M. Y. & Bielinski, S. J., Jul 2019, In : American Heart Journal. 213, p. 30-34 5 p.

Research output: Contribution to journalLetter

2 Scopus citations

Increased levels of copeptin before clinical diagnosis of preelcampsia

Yeung, E. H., Liu, A., Mills, J. L., Zhang, C., Männistö, T., Lu, Z., Tsai, M. Y. & Mendola, P., Jan 1 2014, In : Hypertension. 64, 6, p. 1362-1367 6 p.

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43 Scopus citations

Insulin-like growth factor axis and gestational diabetes mellitus: A longitudinal study in a multiracial cohort

Zhu, Y., Mendola, P., Albert, P. S., Bao, W., Hinkle, S. N., Tsai, M. Y. & Zhang, C., Nov 2016, In : Diabetes. 65, 11, p. 3495-3504 10 p.

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28 Scopus citations

Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: A meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

Ma, Y., Follis, J. L., Smith, C. E., Tanaka, T., Manichaikul, A. W., Chu, A. Y., Samieri, C., Zhou, X., Guan, W., Wang, L., Biggs, M. L., Chen, Y. D. I., Hernandez, D. G., Borecki, I., Chasman, D. I., Rich, S. S., Ferrucci, L., Irvin, M. R., Aslibekyan, S., Zhi, D. & 27 others, Tiwari, H. K., Claas, S. A., Sha, J., Kabagambe, E. K., Lai, C. Q., Parnell, L. D., Lee, Y. C., Amouyel, P., Lambert, J. C., Psaty, B. M., King, I. B., Mozaffarian, D., McKnight, B., Bandinelli, S., Tsai, M. Y., Ridker, P. M., Ding, J., Mstat, K. L., Liu, Y., Sotoodehnia, N., Barberger-Gateau, P., Steffen, L. M., Siscovick, D. S., Absher, D., Arnett, D. K., Ordovás, J. M. & Lemaitre, R. N., Feb 1 2016, In : American Journal of Clinical Nutrition. 103, 2, p. 567-578 12 p.

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13 Scopus citations

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

Asselbergs, F. W., Guo, Y., Van Iperen, E. P. A., Sivapalaratnam, S., Tragante, V., Lanktree, M. B., Lange, L. A., Almoguera, B., Appelman, Y. E., Barnard, J., Baumert, J., Beitelshees, A. L., Bhangale, T. R., Chen, Y. D. I., Gaunt, T. R., Gong, Y., Hopewell, J. C., Johnson, T., Kleber, M. E., Langaee, T. Y. & 150 others, Li, M., Li, Y. R., Liu, K., McDonough, C. W., Meijs, M. F. L., Middelberg, R. P. S., Musunuru, K., Nelson, C. P., O'Connell, J. R., Padmanabhan, S., Pankow, J. S., Pankratz, N., Rafelt, S., Rajagopalan, R., Romaine, S. P. R., Schork, N. J., Shaffer, J., Shen, H., Smith, E. N., Tischfield, S. E., Van Der Most, P. J., Van Vliet-Ostaptchouk, J. V., Verweij, N., Volcik, K. A., Zhang, L., Bailey, K. R., Bailey, K. M., Bauer, F., Boer, J. M. A., Braund, P. S., Burt, A., Burton, P. R., Buxbaum, S. G., Chen, W., Cooper-Dehoff, R. M., Cupples, L. A., Dejong, J. S., Delles, C., Duggan, D., Fornage, M., Furlong, C. E., Glazer, N., Gums, J. G., Hastie, C., Holmes, M. V., Illig, T., Kirkland, S. A., Kivimaki, M., Klein, R., Klein, B. E., Kooperberg, C., Kottke-Marchant, K., Kumari, M., Lacroix, A. Z., Mallela, L., Murugesan, G., Ordovas, J., Ouwehand, W. H., Post, W. S., Saxena, R., Scharnagl, H., Schreiner, P. J., Shah, T., Shields, D. C., Shimbo, D., Srinivasan, S. R., Stolk, R. P., Swerdlow, D. I., Taylor, H. A., Topol, E. J., Toskala, E., Van Pelt, J. L., Van Setten, J., Yusuf, S., Whittaker, J. C., Zwinderman, A. H., Anand, S. S., Balmforth, A. J., Berenson, G. S., Bezzina, C. R., Boehm, B. O., Boerwinkle, E., Casas, J. P., Caulfield, M. J., Clarke, R., Connell, J. M., Cruickshanks, K. J., Davidson, K. W., Day, I. N. M., De Bakker, P. I. W., Doevendans, P. A., Dominiczak, A. F., Hall, A. S., Hartman, C. A., Hengstenberg, C., Hillege, H. L., Hofker, M. H., Humphries, S. E., Jarvik, G. P., Johnson, J. A., Kaess, B. M., Kathiresan, S., Koenig, W., Lawlor, D. A., März, W., Melander, O., Mitchell, B. D., Montgomery, G. W., Munroe, P. B., Murray, S. S., Newhouse, S. J., Onland-Moret, N. C., Poulter, N., Psaty, B., Redline, S., Rich, S. S., Rotter, J. I., Schunkert, H., Sever, P., Shuldiner, A. R., Silverstein, R. L., Stanton, A., Thorand, B., Trip, M. D., Tsai, M. Y., Van Der Harst, P., Van Der Schoot, E., Van Der Schouw, Y. T., Verschuren, W. M. M., Watkins, H., Wilde, A. A. M., Wolffenbuttel, B. H. R., Whitfield, J. B., Hovingh, G. K., Ballantyne, C. M., Wijmenga, C., Reilly, M. P., Martin, N. G., Wilson, J. G., Rader, D. J., Samani, N. J., Reiner, A. P., Hegele, R. A., Kastelein, J. J. P., Hingorani, A. D., Talmud, P. J., Hakonarson, H., Elbers, C. C., Keating, B. J. & Drenos, F., Nov 2 2012, In : American Journal of Human Genetics. 91, 5, p. 823-838 16 p.

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168 Scopus citations

Lipids, obesity and gallbladder disease in women: Insights from genetic studies using the cardiovascular gene-centric 50K SNP array

Rodriguez, S., Gaunt, T. R., Guo, Y., Zheng, J., Barnes, M. R., Tang, W., Danish, F., Johnson, A., Castillo, B. A., Li, Y. R., Hakonarson, H., Buxbaum, S. G., Palmer, T., Tsai, M. Y., Lange, L. A., Ebrahim, S., Smith, G. D., Lawlor, D. A., Folsom, A. R., Hoogeveen, R. & 3 others, Reiner, A., Keating, B. & Day, I. N. M., Jan 1 2016, In : European Journal of Human Genetics. 24, 1, p. 106-112 7 p.

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15 Scopus citations