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  • Sharon E Murphy
2015

Elevated levels of mercapturic acids of acrolein and crotonaldehyde in the urine of Chinese women in Singapore who regularly cook at home

Hecht, S. S., Koh, W. P., Wang, R., Chen, M., Carmella, S. G., Murphy, S. E. & Yuan, J. M., Mar 25 2015, In : PloS one. 10, 3, e0120023.

Research output: Contribution to journalArticle

9 Scopus citations
2012
25 Scopus citations
2015

Abundant Rodent Furan-Derived Urinary Metabolites Are Associated with Tobacco Smoke Exposure in Humans

Grill, A. E., Schmitt, T., Gates, L. A., Lu, D., Bandyopadhyay, D., Yuan, J. M., Murphy, S. E. & Peterson, L. A., Jul 20 2015, In : Chemical research in toxicology. 28, 7, p. 1508-1516 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Effects of monoamine oxidase inhibition on the reinforcing properties of low-dose nicotine

Smith, T. T., Rupprecht, L. E., Cwalina, S. N., Onimus, M. J., Murphy, S. E., Donny, E. C. & Sved, A. F., Aug 1 2016, In : Neuropsychopharmacology. 41, 9, p. 2335-2343 9 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
2015

Nicotine metabolite ratio (3-Hydroxycotinine/Cotinine) in plasma and urine by different analytical methods and laboratories: Implications for clinical implementation

Tanner, J. A., Novalen, M., Jatlow, P., Huestis, M. A., Murphy, S. E., Kaprio, J., Kankaanpää, A., Galanti, L., Stefan, C., George, T. P., Benowitz, N. L., Lerman, C. & Tyndale, R. F., Aug 1 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 8, p. 1239-1246 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
2013

Biomarker evidence of tobacco smoke exposure in children participating in lead screening

Joseph, A., Spector, L., Wickham, K., Janis, G., Winickoff, J., Lindgren, B. & Murphy, S., Dec 2013, In : American journal of public health. 103, 12, p. e54-e59

Research output: Contribution to journalArticle

9 Scopus citations
2016
Open Access
20 Scopus citations
2019

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update

Stram, D. O., Park, S. L., Haiman, C. A., Murphy, S. E., Patel, Y., Hecht, S. S. & Le Marchand, L., Aug 1 2019, In : Journal of the National Cancer Institute. 111, 8, p. 811-819 9 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
2017

CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study

Yuan, J. M., Nelson, H. H., Carmella, S. G., Wang, R., Kuriger-Laber, J., Jin, A., Adams-Haduch, J., Hecht, S. S., Koh, W. P. & Murphy, S. E., 2017, In : Carcinogenesis. 38, 4, p. 411-418 8 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Nicotine metabolism and smoking: Ethnic differences in the role of P450 2A6

Murphy, S. E., Jan 1 2017, In : Chemical research in toxicology. 30, 1, p. 410-419 10 p.

Research output: Contribution to journalReview article

13 Scopus citations
2013

Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption

Bloom, A. J., Murphy, S. E., Martinez, M., Von Weymarn, L. B., Bierut, L. J. & Goate, A., Feb 2013, In : Pharmacogenetics and genomics. 23, 2, p. 62-68 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Exposure to different sources of secondhand smoke during pregnancy and its effect on urinary cotinine and tobacco-specific nitrosamine (NNAL) concentrations

Vardavas, C. I., Fthenou, E., Patelarou, E., Bagkeris, E., Murphy, S., Hecht, S. S., Connolly, G. N., Chatzi, L. & Kogevinas, M., May 2013, In : Tobacco control. 22, 3, p. 194-200 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
2015

Combined analysis of the tobacco metabolites cotinine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine

Kotandeniya, D., Carmella, S. G., Ming, X., Murphy, S. E. & Hecht, S. S., Feb 3 2015, In : Analytical chemistry. 87, 3, p. 1514-1517 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
2013
32 Scopus citations
2018

Effect of immediate vs gradual reduction in nicotine content of cigarettes on biomarkers of smoke exposure a randomized clinical trial

Hatsukami, D. K., Luo, X., Jensen, J. A., Al'Absi, M., Allen, S. S., Carmella, S. G., Chen, M., Cinciripini, P. M., Denlinger-Apte, R., Drobes, D. J., Koopmeiners, J. S., Lane, T., Le, C. T., Leischow, S., Luo, K., Joseph McClernon, F., Murphy, S. E., Paiano, V., Robinson, J. D., Severson, H. & 8 others, Sipe, C., Strasser, A. A., Strayer, L. G., Tang, M. K., Vandrey, R., Hecht, S. S., Benowitz, N. L. & Donny, E. C., Sep 4 2018, In : JAMA - Journal of the American Medical Association. 320, 9, p. 880-891 12 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations
2020

Mouth-level nicotine intake estimates from discarded filter butts to examine compensatory smoking in low nicotine cigarettes

Smith, T. T., Koopmeiners, J. S., Hatsukami, D. K., Tessier, K. M., Benowitz, N. L., Murphy, S. E., Strasser, A. A., Tidey, J. W., Blount, B. C., Valentin, L., Cardenas, R. B., Watson, C., Pirkle, J. L. & Donny, E. C., 2020, In : Cancer Epidemiology Biomarkers and Prevention. 29, 3, p. 643-649 7 p.

Research output: Contribution to journalArticle

2013

Dose-response effects of spectrum research cigarettes

Hatsukami, D. K., Heishman, S. J., Vogel, R. I., Denlinger, R. L., Roper-Batker, A. N., Mackowick, K. M., Jensen, J., Murphy, S. E., Thomas, B. F. & Donny, E., Jun 2013, In : Nicotine and Tobacco Research. 15, 6, p. 1113-1121 9 p.

Research output: Contribution to journalArticle

49 Scopus citations
2020

A Randomized Clinical Trial Examining the Effects of Instructions for Electronic Cigarette Use on Smoking-Related Behaviors and Biomarkers of Exposure

Hatsukami, D. K., Meier, E., Lindgren, B. R., Anderson, A., Reisinger, S. A., Norton, K. J., Strayer, L. S., Jensen, J. A., Dick, L., Murphy, S. E., Carmella, S. G., Tang, M. K., Chen, M., Hecht, S. S., O'connor, R. J. & Shields, P. G., Aug 24 2020, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 22, 9, p. 1524-1532 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

The detection of biomarkers of tobacco smoke exposure in wound fluid: A pilot study

Lassig, A. A. D., Yueh, B., Murphy, S. E., Fernandes, P. G., Banks, K. M., Wickham, K. M. & Joseph, A. M., Nov 1 2013, In : Plastic and reconstructive surgery. 132, 5, p. 892e-894e

Research output: Contribution to journalLetter

2016

Clinical trial of 2-phenethyl isothiocyanate as an inhibitor of metabolic activation of a tobacco-specific lung carcinogen in cigarette smokers

Yuan, J. M., Stepanov, I., Murphy, S. E., Wang, R., Allen, S., Jensen, J., Strayer, L., Adams-Haduch, J., Upadhyaya, P., Le, C., Kurzer, M. S., Nelson, H. H., Yu, M. C., Hatsukami, D. & Hecht, S. S., May 2016, In : Cancer Prevention Research. 9, 5, p. 396-405 10 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes

Nardone, N., Donny, E. C., Hatsukami, D. K., Koopmeiners, J. S., Murphy, S. E., Strasser, A. A., Tidey, J. W., Vandrey, R. & Benowitz, N. L., Dec 1 2016, In : Addiction. 111, 12, p. 2208-2216 9 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
Open Access
15 Scopus citations
2018

Web-delivered multimedia training materials for the self-collection of dried blood spots: A formative project

Allen, A. M., Lundeen, K., Murphy, S. E., Spector, L. & Harlow, B. L., Nov 2018, In : Journal of medical Internet research. 20, 11, e11025.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers

St.Helen, G., Benowitz, N. L., Ko, J., Jacob, P., Gregorich, S. E., Pérez-Stable, E. J., Murphy, S. E., Hecht, S. S., Hatsukami, D. K. & Donny, E. C., Jan 1 2019, In : Journal of Exposure Science and Environmental Epidemiology.

Research output: Contribution to journalArticle

1 Scopus citations
2020

Cigarette Smokers Versus Cousers of Cannabis and Cigarettes: Exposure to Toxicants

Meier, E., Vandrey, R., Rubin, N., Pacek, L. R., Jensen, J. A., Donny, E. C., Hecht, S. S., Carmella, S. G., Murphy, S. E., Luo, X., Stepanov, I., Ikuemonisan, J., Severson, H., Al'absi, M. & Hatsukami, D. K., Jul 16 2020, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 22, 8, p. 1383-1389 7 p.

Research output: Contribution to journalArticle

Relationships between the nicotine metabolite ratio and a panel of exposure and effect biomarkers: Findings from two studies of U.S. commercial cigarette smokers

Carroll, D. M., Murphy, S. E., Benowitz, N. L., Strasser, A. A., Kotlyar, M., Hecht, S. S., Carmella, S. G., McClernon, F. J., Pacek, L. R., Dermody, S. S., Vandrey, R. G., Donny, E. C. & Hatsukami, D. K., 2020, In : Cancer Epidemiology Biomarkers and Prevention. 29, 4, p. 871-879 9 p.

Research output: Contribution to journalArticle

Open Access
2019

Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation

Carmella, S. G., Heskin, A. K., Tang, M. K., Jensen, J., Luo, X., Le, C. T., Murphy, S. E., Benowitz, N. L., Joseph McClernon, F., Vandrey, R., Allen, S. S., Denlinger-Apte, R., Cinciripini, P. M., Strasser, A. A., Al’Absi, M., Robinson, J. D., Donny, E. C., Hatsukami, D. K. & Hecht, S. S., Apr 2019, In : PloS one. 14, 4, e0215853.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2014
23 Scopus citations
2015

Effects of MAO inhibition and a combination of minor alkaloids, β-carbolines, and acetaldehyde on nicotine self-administration in adult male rats

Smith, T. T., Schaff, M. B., Rupprecht, L. E., Schassburger, R. L., Buffalari, D. M., Murphy, S. E., Sved, A. F. & Donny, E. C., Oct 1 2015, In : Drug and alcohol dependence. 155, p. 243-252 10 p., 5706.

Research output: Contribution to journalArticle

21 Scopus citations
2018

Collaborative method performance study of the measurement of nicotine, its metabolites, and total nicotine equivalents in human urine

Wang, L., Bernert, J. T., Benowitz, N. L., Feng, J., Jacob, P., McGahee, E., Caudill, S. P., Scherer, G., Scherer, M., Pluym, N., Doig, M. V., Newland, K., Murphy, S. E., Caron, N. J., Sander, L. C., Shimizu, M., Yamazaki, H., Kim, S., Langman, L. J., Pritchett, J. S. & 4 others, Sniegoski, L. T., Li, Y., Blount, B. C. & Pirkle, J. L., Sep 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 9, p. 1083-1090 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2016

Novel association of genetic markers affecting CYP2A6 activity and lung cancer risk

Patel, Y. M., Park, S. L., Han, Y., Wilkens, L. R., Bickeböller, H., Rosenberger, A., Caporaso, N., Landi, M. T., Brüske, I., Risch, A., Wei, Y., Christiani, D. C., Brennan, P., Houlston, R., McKay, J., McLaughlin, J., Hung, R., Murphy, S., Stram, D. O., Amos, C. & 1 others, Marchand, L. L., Oct 1 2016, In : Cancer Research. 76, 19, p. 5768-5776 9 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
2018

Misclassification of self-reported smoking in adult survivors of childhood cancer

Huang, I. C., Klosky, J. L., Young, C. M., Murphy, S. E., Krull, K. K., Srivastava, D. K., Hudson, M. M. & Robison, L. L., Sep 2018, In : Pediatric Blood and Cancer. 65, 9, e27240.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2013

A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele

Bloom, A. J., Harari, O., Martinez, M., Zhang, X., McDonald, S. A., Murphy, S. E. & Goate, A., Mar 2013, In : Pharmacogenetics and genomics. 23, 3, p. 107-116 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2012

Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6

Bloom, A. J., Harari, O., Martinez, M., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Rice, J. P., Murphy, S. E., Bierut, L. J. & Goate, A., Jul 2012, In : Human molecular genetics. 21, 13, p. 3050-3062 13 p., dds114.

Research output: Contribution to journalArticle

28 Scopus citations
2018

Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain

Teitelbaum, A. M., Murphy, S. E., Akk, G., Baker, T. B., Germann, A., von Weymarn, L. B., Bierut, L. J., Goate, A., Kharasch, E. D. & Bloom, A. J., Jan 1 2018, In : Pharmacogenomics Journal. 18, 1, p. 136-143 8 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage

McElroy, J. P., Carmella, S. G., Heskin, A. K., Tang, M. K., Murphy, S. E., Reisinger, S. A., Jensen, J. A., Hatsukami, D. K., Hecht, S. S. & Shields, P. G., Nov 1 2018, In : PloS one. 14, 6, e0218386.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2012

CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5′(1′)iminium ion

Von Weymarn, L. B., Retzlaff, C. & Murphy, S. E., Nov 2012, In : Journal of Pharmacology and Experimental Therapeutics. 343, 2, p. 307-315 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2018

Influence of UGT2B10 Genotype on Urinary Excretion of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol- N- glucuronide by African American Smokers

Murphy, S. E., Von Weymarn, L. B., Parenteau, M., Stepanov, I., Tiirikainen, M., Lemarchand, L. & Park, S. L., Mar 19 2018, In : Chemical research in toxicology. 31, 3, p. 168-175 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2014

Prenatal tobacco exposure and cotinine in newborn dried blood spots

Spector, L. G., Murphy, S. E., Wickham, K. M., Lindgren, B. & Joseph, A. M., Jun 1 2014, In : Pediatrics. 133, 6, p. e1632-e1638

Research output: Contribution to journalArticle

22 Scopus citations
2017

Reduced nicotine content cigarettes and use of alternative nicotine products: exploratory trial

Hatsukami, D. K., Luo, X., Dick, L., Kangkum, M., Allen, S. S., Murphy, S. E., Hecht, S. S., Shields, P. G. & al'Absi, M., Jan 1 2017, In : Addiction. 112, 1, p. 156-167 12 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations
2019

Effects of 6-Week Use of Very Low Nicotine Content Cigarettes in Smokers With Serious Mental Illness

Tidey, J. W., Colby, S. M., Denlinger-Apte, R. L., Goodwin, C., Cioe, P. A., Cassidy, R. N., Swift, R. M., Lindgren, B. R., Rubin, N., Murphy, S. E., Hecht, S. S., Hatsukami, D. K. & Donny, E. C., Dec 23 2019, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 21, 1, p. S38-S45

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2013

Reduced nicotine content cigarettes and nicotine patch

Hatsukami, D. K., Hertsgaard, L. A., Vogel, R. I., Jensen, J. A., Murphy, S. E., Hecht, S. S., Carmella, S. G., Al'Absi, M., Joseph, A. M. & Allen, S. S., Jun 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 6, p. 1015-1024 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
2016

Randomised clinical trial of snus versus medicinal nicotine among smokers interested in product switching

Hatsukami, D. K., Severson, H., Anderson, A., Vogel, R. I., Jensen, J., Broadbent, B., Murphy, S. E., Carmella, S. G. & Hecht, S. S., May 2016, In : Tobacco control. 25, 3, p. 267-274 8 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
2015

Evidence supporting product standards for carcinogens in smokeless tobacco products

Hatsukami, D. K., Stepanov, I., Severson, H., Jensen, J. A., Lindgren, B. R., Horn, K., Khariwala, S. S., Martin, J., Carmella, S. G., Murphy, S. E. & Hecht, S. S., Jan 1 2015, In : Cancer Prevention Research. 8, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2018

In Vivo Stable Isotope Labeling and Mass Spectrometry-Based Metabolic Profiling of a Potent Tobacco-Specific Carcinogen in Rats

Dator, R., von Weymarn, L. B., Villalta, P. W., Hooyman, C. J., Maertens, L. A., Upadhyaya, P., Murphy, S. E. & Balbo, S., Oct 16 2018, In : Analytical Chemistry. 90, 20, p. 11863-11872 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2019

Diet, secondhand smoke, and glycated hemoglobin (HbA1c) levels among Singapore Chinese adults

Moore, B. F., Butler, L. M., Bachand, A. M., Salim, A., Reynolds, S. J., Wang, R., Nelson, T. L., Peel, J. L., Murphy, S. E., Koh, W. P., Yuan, J. M. & Clark, M. L., Dec 2 2019, In : International journal of environmental research and public health. 16, 24, 5148.

Research output: Contribution to journalArticle

Open Access
2013

The contribution of common UGT2B10 and CYP2A6 alleles to variation in nicotine glucuronidation among european americans

Bloom, A. J., Von Weymarn, L. B., Martinez, M., Bierut, L. J., Goate, A. & Murphy, S. E., Dec 1 2013, In : Pharmacogenetics and genomics. 23, 12, p. 706-716 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification

Narayanapillai, S. C., Von Weymarn, L. B., Carmella, S. G., Leitzman, P., Paladino, J., Upadhyaya, P., Hecht, S. S., Murphy, S. E. & Xing, C., Mar 1 2016, In : Drug Metabolism and Disposition. 44, 3, p. 422-427 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2017

Association of CYP2A6 activity with lung cancer incidence in smokers: The Multiethnic Cohort Study

Park, S. L., Murphy, S. E., Wilkens, L. R., Stram, D. O., Hecht, S. S. & Le Marchand, L., May 2017, In : PloS one. 12, 5, e0178435.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2015

Genetic determinants of CYP2A6 activity across racial/ ethnic groups with different risks of lung cancer and effect on their smoking intensity

Park, S. L., Tiirikainen, M. I., Patel, Y. M., Wilkens, L. R., Stram, D. O., Marchand, L. L. & Murphy, S. E., Oct 17 2015, In : Carcinogenesis. 37, 3, p. 269-279 11 p.

Research output: Contribution to journalArticle

25 Scopus citations