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Author

  • Richard Brundage
2014

Ethnic and genetic factors in methadone pharmacokinetics: A population pharmacokinetic study

Bart, G., Lenz, S., Straka, R. J. & Brundage, R. C., Dec 1 2014, In : Drug and alcohol dependence. 145, p. 185-193 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2019

A Gallbladder-Based Enterohepatic Circulation Model for Pharmacokinetic Studies

Okour, M. & Brundage, R. C., Aug 1 2019, In : European Journal of Drug Metabolism and Pharmacokinetics. 44, 4, p. 493-504 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2020
2011

Population pharmacokinetics of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (Triapine®) in cancer patients

Kolesar, J., Brundage, R. C., Pomplun, M., Alberti, D., Holen, K., Traynor, A., Ivy, P. & Wilding, G., Feb 1 2011, In : Cancer chemotherapy and pharmacology. 67, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

32 Scopus citations
2016
Open Access
6 Scopus citations
2012

Population pharmacokinetics of carbamazepine in elderly patients

Punyawudho, B., Ramsay, E. R., Brundage, R. C., MacIas, F. M., Collins, J. F. & Birnbaum, A. K., Apr 2012, In : Therapeutic drug monitoring. 34, 2, p. 176-181 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Interrelationships among cortisol, 17-hydroxyprogesterone, and androstenendione exposures in the management of children with congenital adrenal hyperplasia

Sarafoglou, K., Zimmerman, C. L., Gonzalez-Bolanos, M. T., Willis, B. A. & Brundage, R., Jan 2015, In : Journal of Investigative Medicine. 63, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Population pharmacokinetic and concentration-QTc models for moxifloxacin: Pooled analysis of 20 thorough QT studies

Florian, J. A., Tornøe, C. W., Brundage, R., Parekh, A. & Garnett, C. E., Aug 1 2011, In : Journal of Clinical Pharmacology. 51, 8, p. 1152-1162 11 p.

Research output: Contribution to journalArticle

124 Scopus citations

Effect of radiation on the penetration of irinotecan in rat cerebrospinal fluid

Khatri, A., Gaber, M. W., Brundage, R. C., Naimark, M. D., Hanna, S. K., Stewart, C. F. & Kirstein, M. N., Sep 1 2011, In : Cancer chemotherapy and pharmacology. 68, 3, p. 721-731 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Modeling Enterohepatic Circulation

Okour, M. & Brundage, R. C., Oct 1 2017, In : Current Pharmacology Reports. 3, 5, p. 301-313 13 p.

Research output: Contribution to journalReview article

5 Scopus citations
2014

SLC28A3 genotype and gemcitabine rate of infusion affect dFdCTP metabolite disposition in patients with solid tumours

Khatri, A., Williams, B. W., Fisher, J., Brundage, R. C., Gurvich, V. J., Lis, L. G., Skubitz, K. M., Dudek, A. Z., Greeno, E. W., Kratzke, R. A., Lamba, J. K. & Kirstein, M. N., Jan 21 2014, In : British Journal of Cancer. 110, 2, p. 304-312 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pharmacometric characterization of efavirenz developmental pharmacokinetics and pharmacogenetics in HIV-Infected children

Salem, A. H., Fletcher, C. V. & Brundage, R. C., Jan 2014, In : Antimicrobial agents and chemotherapy. 58, 1, p. 136-143 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2012

Pharmacodynamic modeling of sequence-dependent antitumor activity of insulin-like growth factor blockade and gemcitabine

Khatri, A., Brundage, R. C., Hull, J. M., Williams, B. W., Yee, D. & Kirstein, M. N., Mar 1 2012, In : AAPS Journal. 14, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2011

Atazanavir and atazanavir/ritonavir pharmacokinetics in HIV-infected infants, children, and adolescents

Kiser, J. J., Rutstein, R. M., Samson, P., Graham, B., Aldrovandi, G., Mofenson, L. M., Smith, E., Schnittman, S., Fenton, T., Brundage, R. C. & Fletcher, C. V., Jul 31 2011, In : AIDS. 25, 12, p. 1489-1496 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Bioavailability of Intranasal vs. Rectal Diazepam

Ivaturi, V., Kriel, R., Brundage, R., Loewen, G., Mansbach, H. & Cloyd, J. C., Feb 1 2013, In : Epilepsy Research. 103, 2-3, p. 254-261 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
2014

Bayesian approach to estimate AUC, partition coefficient and drug targeting index for studies with serial sacrifice design

Wang, T., Baron, K., Zhong, W., Brundage, R. & Elmquist, W., Mar 2014, In : Pharmaceutical research. 31, 3, p. 649-659 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013

Population pharmacokinetics of rifampicin in Mexican patients with tuberculosis

Milán Segovia, R. C., Domínguez Ramírez, A. M., Jung Cook, H., Magaña Aquino, M., Vigna Pérez, M., Brundage, R. C. & Romano Moreno, S., Feb 2013, In : Journal of Clinical Pharmacy and Therapeutics. 38, 1, p. 56-61 6 p.

Research output: Contribution to journalArticle

18 Scopus citations
2019

Orphan drug development: the increasing role of clinical pharmacology

Ahmed, M. A., Okour, M., Brundage, R. & Kartha, R. V., Oct 1 2019, In : Journal of Pharmacokinetics and Pharmacodynamics. 46, 5, p. 395-409 15 p.

Research output: Contribution to journalReview article

4 Scopus citations
2016

Prospective studies of infectious mononucleosis in university students

Grimm, J. M., Schmeling, D. O., Dunmire, S. K., Knight, J. A., Mullan, B. D., Ed, J. A., Brundage, R. C., Hogquist, K. A. & Balfour, H. H., Aug 12 2016, In : Clinical and Translational Immunology. 5, 8, e94.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2013

Intravenous topiramate: Comparison of pharmacokinetics and safety with the oral formulation in healthy volunteers

Clark, A. M., Kriel, R. L., Leppik, I. E., Marino, S. E., Mishra, U., Brundage, R. C. & Cloyd, J. C., Jun 1 2013, In : Epilepsia. 54, 6, p. 1099-1105 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2017

Personalized Tacrolimus (TAC) Dosing Using Genetic Variants in Caucasian Kidney Transplant (Tx) Recipients

Margraf, D., Brundage, R., Schladt, D., Guan, W., Wu, B., Remmel, R., Dorr, C., Berglund, D., Mannon, R. & Matas, A., 2017, p. 736. 1 p.

Research output: Contribution to conferenceAbstract

2012
13 Scopus citations
2011
4 Scopus citations
2014

Model-based lamotrigine clearance changes during pregnancy: Clinical implication

Polepally, A. R., Pennell, P. B., Brundage, R. C., Stowe, Z. N., Newport, D. J., Viguera, A. C., Ritchie, J. C. & Birnbaum, A. K., 2014, In : Annals of Clinical and Translational Neurology. 1, 2, p. 99-106 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2017

Pharmacokinetics and Saturable Absorption of Gabapentin in Nursing Home Elderly Patients

Ahmed, G. F., Bathena, S. P. R., Brundage, R. C., Leppik, I. E., Conway, J. M., Schwartz, J. B. & Birnbaum, A. K., Mar 1 2017, In : AAPS Journal. 19, 2, p. 551-556 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Personalized fludarabine dosing to reduce nonrelapse mortality in hematopoietic stem-cell transplant recipients receiving reduced intensity conditioning

Sanghavi, K. J., Wiseman, A., Kirstein, M. N., Cao, Q., Brundage, R., Jensen, K., Rogosheske, J., Kurtzweil, A., Long-Boyle, J., Wagner, J. E., Warlick, E. D., Brunstein, C. G., Weisdorf, D. J. & Jacobson, P. A., Sep 1 2016, In : Translational Research. 175, p. 103-115.e4

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2017

Genotype-guided tacrolimus dosing in African-American kidney transplant recipients

Sanghavi, K., Brundage, R. C., Miller, M. B., Schladt, D. P., Israni, A. K., Guan, W., Oetting, W. S., Mannon, R. B., Remmel, R. P., Matas, A. J. & Jacobson, P. A., Jan 1 2017, In : Pharmacogenomics Journal. 17, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations
2016

Operational Characteristics of Linear Concentration-QT Models for Assessing QTc Interval in the Thorough QT and Phase I Clinical Studies

Garnett, C., Needleman, K., Liu, J., Brundage, R. & Wang, Y., Aug 1 2016, In : Clinical pharmacology and therapeutics. p. 170-178 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2014
11 Scopus citations
2013
10 Scopus citations
2019
Open Access
2 Scopus citations
2015

Comparison of cortisol exposures and pharmacodynamic adrenal steroid responses to hydrocortisone suspension VS. Commercial tablets

Sarafoglou, K., Gonzalez-Bolanos, M. T., Zimmerman, C. L., Boonstra, T., Yaw Addo, O. & Brundage, R., Apr 2015, In : Journal of Clinical Pharmacology. 55, 4, p. 452-457 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019

Pharmacokinetics-pharmacodynamics of sertraline as an antifungal in HIV-infected Ugandans with cryptococcal meningitis

ASTRO-CM Study Team, Dec 1 2019, In : Journal of Pharmacokinetics and Pharmacodynamics. 46, 6, p. 565-576 12 p.

Research output: Contribution to journalArticle

2011

Dosing equation for tacrolimus using genetic variants and clinical factors

Passey, C., Birnbaum, A. K., Brundage, R. C., Oetting, W. S., Israni, A. K. & Jacobson, P. A., Dec 2011, In : British Journal of Clinical Pharmacology. 72, 6, p. 948-957 10 p.

Research output: Contribution to journalArticle

106 Scopus citations
2019

Brain distributional kinetics of a novel MDM2 inhibitor SAR405838: Implications for use in brain tumor therapy

Kim, M., Laramy, J. K., Gampa, G., Parrish, K. E., Brundage, R., Sarkaria, J. N. & Elmquist, W. F., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 12, p. 1403-1414 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2012

Steady-state carbamazepine pharmacokinetics following oral and stable-labeled intravenous administration in epilepsy patients: Effects of race and sex

Marino, S. E., Birnbaum, A. K., Leppik, I. E., Conway, J. M., Musib, L. C., Brundage, R., Ramsay, R. E., Pennell, P. B., White, J. R., Gross, C. R., Rarick, J. O., Mishra, U. & Cloyd, J. C., Mar 2012, In : Clinical pharmacology and therapeutics. 91, 3, p. 483-488 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
2013

A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers

Agarwal, S. K., Kriel, R. L., Brundage, R., Ivaturi, V. D. & Cloyd, J. C., Aug 1 2013, In : Epilepsy Research. 105, 3, p. 362-367 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
2016

Epstein-Barr virus dynamics in asymptomatic immunocompetent adults: An intensive 6-month study

Johnson, K. H., Webb, C. H., Schmeling, D. O., Brundage, R. C. & Balfour, H. H., May 13 2016, In : Clinical and Translational Immunology. 5, e81.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2020

An integrated PK-PD model for cortisol and the 17-hydroxyprogesterone and androstenedione biomarkers in children with congenital adrenal hyperplasia

Al-Kofahi, M., Ahmed, M. A., Jaber, M. M., Tran, T. N., Willis, B. A., Zimmerman, C. L., Gonzalez-Bolanos, M. T., Brundage, R. C. & Sarafoglou, K. M., 2020, (Accepted/In press) In : British Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Open Access
2019
1 Scopus citations
2012

Quantitative Epstein-Barr virus shedding and its correlation with the risk of post-transplant lymphoproliferative disorder

Holman, C. J., Karger, A., Mullan, B. D., Brundage, R. & Balfour, H. H., Sep 2012, In : Clinical Transplantation. 26, 5, p. 741-747 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
2017

CYP2C9 Genotype-Dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites

Flora, D. R., Rettie, A. E., Brundage, R. C. & Tracy, T. S., Jan 1 2017, In : Journal of Clinical Pharmacology. 57, 3, p. 382-393 12 p.

Research output: Contribution to journalArticle

23 Scopus citations
2013

Intravenous topiramate: Safety and pharmacokinetics following a single dose in patients with epilepsy or migraines taking oral topiramate

Clark, A. M., Kriel, R. L., Leppik, I. E., White, J. R., Henry, T. R., Brundage, R. C. & Cloyd, J. C., Jun 2013, In : Epilepsia. 54, 6, p. 1106-1111 6 p.

Research output: Contribution to journalArticle

18 Scopus citations
2020
1 Scopus citations
2016
Open Access
3 Scopus citations
2015
8 Scopus citations
2012

Affiliation between the american society of pharmacometrics and the journal of pharmacokinetics and pharmacodynamics

D'Argenio, D. Z., Gastonguay, M. R., Brundage, R., Miller, R., Tannenbaum, S. J. & Pfister, M., Feb 1 2012, In : Journal of Pharmacokinetics and Pharmacodynamics. 39, 1, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
2016
Open Access
3 Scopus citations