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  • Stephen S Hecht
2016

Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis

Smith, M. T., Guyton, K. Z., Gibbons, C. F., Fritz, J. M., Portier, C. J., Rusyn, I., DeMarini, D. M., Caldwell, J. C., Kavlock, R. J., Lambert, P. F., Hecht, S. S., Bucher, J. R., Stewart, B. W., Baan, R. A., Cogliano, V. J. & Straif, K., Jun 2016, In : Environmental health perspectives. 124, 6, p. 713-721 9 p.

Research output: Contribution to journalReview article

169 Scopus citations
2011
21 Scopus citations
2012

Kinetics of DNA adduct formation in the oral cavity after drinking alcohol

Balbo, S., Meng, L., Bliss, R. L., Jensen, J. A., Hatsukami, D. K. & Hecht, S. S., Apr 1 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 4, p. 601-608 8 p.

Research output: Contribution to journalArticle

44 Scopus citations
2020

Effects of 2-phenethyl isothiocyanate on metabolism of 1,3-butadiene in smokers

Boldry, E. J., Yuan, J. M., Carmella, S. G., Wang, R., Tessier, K., Hatsukami, D. K., Hecht, S. S. & Tretyakova, N. Y., Jan 1 2020, In : Cancer Prevention Research. 13, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

2013
8 Scopus citations
2019

Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects

Hatsukami, D. K., Luo, X., Heskin, A. K., Tang, M. K., Carmella, S. G., Jensen, J., Robinson, J. D., Vandrey, R., Drobes, D. J., Strasser, A. A., al'Absi, M., Leischow, S., Cinciripini, P. M., Koopmeiners, J., Ikuemonisan, J., Benowitz, N. L., Donny, E. C. & Hecht, S. S., Oct 1 2019, In : Addiction. 114, 10, p. 1824-1833 10 p.

Research output: Contribution to journalArticle

2016

Metabolites of the polycyclic aromatic hydrocarbon phenanthrene in the urine of cigarette smokers from five ethnic groups with differing risks for lung cancer

Patel, Y. M., Park, S. L., Carmella, S. G., Paiano, V., Olvera, N., Stram, D. O., Haiman, C. A., Le Marchand, L. & Hecht, S. S., Jun 1 2016, In : PloS one. 11, 6, e0156203.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2019

Effects of 6-Week Use of Very Low Nicotine Content Cigarettes in Smokers With Serious Mental Illness

Tidey, J. W., Colby, S. M., Denlinger-Apte, R. L., Goodwin, C., Cioe, P. A., Cassidy, R. N., Swift, R. M., Lindgren, B. R., Rubin, N., Murphy, S. E., Hecht, S. S., Hatsukami, D. K. & Donny, E. C., Dec 23 2019, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 21, 1, p. S38-S45

Research output: Contribution to journalArticle

Open Access
2020

The Impact of One-week Dietary Supplementation with Kava on Biomarkers of Tobacco Use and Nitrosamine-based Carcinogenesis Risk among Active Smokers

Wang, Y., Narayanapillai, S. C., Tessier, K. M., Strayer, L. G., Upadhyaya, P., Hu, Q., Kingston, R., Salloum, R. G., Lu, J., Hecht, S. S., Hatsukami, D. K., Fujioka, N. & Xing, C., May 1 2020, In : Cancer prevention research (Philadelphia, Pa.). 13, 5, p. 483-492 10 p.

Research output: Contribution to journalArticle

2014

Chemoprevention of esophageal cancer with black raspberries, their component anthocyanins, and a major anthocyanin metabolite, protocatechuic acid

Peiffer, D. S., Zimmerman, N. P., Wang, L. S., Ransom, B. W. S., Carmella, S. G., Kuo, C. T., Siddiqui, J., Chen, J. H., Oshima, K., Huang, Y. W., Hecht, S. S. & Stoner, G. D., Jun 2014, In : Cancer Prevention Research. 7, 6, p. 574-584 11 p.

Research output: Contribution to journalArticle

58 Scopus citations
2020

Relationships between the nicotine metabolite ratio and a panel of exposure and effect biomarkers: Findings from two studies of U.S. commercial cigarette smokers

Carroll, D. M., Murphy, S. E., Benowitz, N. L., Strasser, A. A., Kotlyar, M., Hecht, S. S., Carmella, S. G., McClernon, F. J., Pacek, L. R., Dermody, S. S., Vandrey, R. G., Donny, E. C. & Hatsukami, D. K., Jan 1 2020, In : Cancer Epidemiology Biomarkers and Prevention. 29, 4, p. 871-879 9 p.

Research output: Contribution to journalArticle

Open Access
2019

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage

McElroy, J. P., Carmella, S. G., Heskin, A. K., Tang, M. K., Murphy, S. E., Reisinger, S. A., Jensen, J. A., Hatsukami, D. K., Hecht, S. S. & Shields, P. G., Jan 1 2019, In : PloS one. 14, 6, e0218386.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2020

A Randomized Clinical Trial of Snus Examining the Effect of Complete Versus Partial Cigarette Substitution on Smoking-Related Behaviors, and Biomarkers of Exposure

Meier, E., Lindgren, B. R., Anderson, A., Reisinger, S. A., Norton, K. J., Jensen, J., Strayer, L., Dick, L., Tang, M. K., Chen, M., Carmella, S. G., Hecht, S. S., Murphy, S. E., Yang, J., Stepanov, I., O'Connor, R. J., Shields, P. G. & Hatsukami, D. K., Apr 17 2020, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 22, 4, p. 473-481 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Longitudinal study of [D10]phenanthrene metabolism by the diol epoxide pathway in smokers

Hecht, S. S., Hochalter, J. B., Carmella, S. G., Zhang, Y., Rauch, D. M., Fujioka, N., Jensen, J. & Hatsukami, D. K., Mar 1 2013, In : Biomarkers. 18, 2, p. 144-150 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

It is time to regulate carcinogenic tobacco-specific nitrosamines in cigarette tobacco

Hecht, S. S., Jul 2014, In : Cancer Prevention Research. 7, 7, p. 639-647 9 p.

Research output: Contribution to journalComment/debate

29 Scopus citations
2016

FEMA expert panel review of p-mentha-1,8-dien-7-al genotoxicity testing results

Cohen, S. M., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Smith, R. L., Bastaki, M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Dec 1 2016, In : Food and Chemical Toxicology. 98, p. 201-209 9 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations
2013

Continuing excellence for chemical research in toxicology

Hecht, S. S., Jan 18 2013, In : Chemical research in toxicology. 26, 1, 1 p.

Research output: Contribution to journalEditorial

2016

Evaluation of Nitrosamide Formation in the Cytochrome P450-Mediated Metabolism of Tobacco-Specific Nitrosamines

Carlson, E. S., Upadhyaya, P. & Hecht, S. S., Dec 19 2016, In : Chemical research in toxicology. 29, 12, p. 2194-2205 12 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2011

GRAS flavoring substances 25

Smith, R. L., Waddell, W. J., Cohen, S. M., Fukushima, S., Gooderham, N. J., Hecht, S. S., Marnett, L. J., Portoghese, P. S., Rietjens, I. M. C. M., Adams, T. B., Gavin, C. L., Mcgowen, M. M. & Taylor, S. V., Jul 2011, In : Food Technology. 65, 7, p. 44-75 32 p.

Research output: Contribution to journalArticle

18 Scopus citations
2012

The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA

Upadhyaya, P., Kumar, A., Byun, H. S., Bittman, R., Saba, J. D. & Hecht, S. S., Jul 20 2012, In : Biochemical and Biophysical Research Communications. 424, 1, p. 18-21 4 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

More than 500 trillion molecules of strong carcinogens per cigarette: Use in product labelling?

Hecht, S. S., Sep 1 2011, In : Tobacco control. 20, 5, 1 p.

Research output: Contribution to journalLetter

8 Scopus citations
2017
Open Access
7 Scopus citations
2013

Levels of (S)-N′-nitrosonornicotine in U.S. tobacco products

Stepanov, I., Yershova, K., Carmella, S., Upadhyaya, P. & Hecht, S. S., Jul 1 2013, In : Nicotine and Tobacco Research. 15, 7, p. 1305-1310 6 p.

Research output: Contribution to journalArticle

18 Scopus citations
2018

A New Editorial Team for CRT

Hecht, S. S., Jan 16 2018, In : Chemical research in toxicology. 31, 1, 1 p.

Research output: Contribution to journalEditorial

Open Access
2019

Recent studies on DNA adducts resulting from human exposure to tobacco smoke

Ma, B., Stepanov, I. & Hecht, S. S., Jan 1 2019, In : Toxics. 7, 1, 16.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations
2018

Acrolein exposure in hookah smokers and non-smokers exposed to hookah tobacco secondhand smoke: Implications for regulating hookah tobacco products

Kassem, N. O. F., Kassem, N. O., Liles, S., Zarth, A. T., Jackson, S. R., Daffa, R. M., Chatfield, D. A., Carmella, S. G., Hecht, S. S. & Hovell, M. F., Mar 6 2018, In : Nicotine and Tobacco Research. 20, 4, p. 492-501 10 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2012

Anthocyanins and cancer prevention

Wang, L. S., Carmella, S., Keyes, R., Kuo, C. T., Huang, Y. W., Hecht, S. S. & Stoner, G. D., Dec 1 2012, Nutraceuticals and Cancer. Springer Netherlands, Vol. 9789400726307. p. 201-229 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations
2014

An approach to the evaluation of berries for cancer prevention with emphasis on esophageal cancer

Stoner, G. D., Wang, L. S., Kresty, L. A., Peiffer, D., Kuo, C. T., Huang, Y. W., Wang, D., Ransom, B., Carmella, S. & Hecht, S. S., Jan 13 2014, Cancer Prevention: Dietary Factors and Pharmacology. Bode, A. M. & Dong, Z. (eds.). p. 107-133 27 p. (Methods in Pharmacology and Toxicology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai cohort study: Remarkable coherence with rat tumor sites

Stepanov, I., Sebero, E., Wang, R., Gao, Y. T., Hecht, S. S. & Yuan, J. M., May 15 2014, In : International Journal of Cancer. 134, 10, p. 2278-2283 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011
24 Scopus citations
2017

Polycyclic Aromatic Hydrocarbon Biomarker Levels among Smokers who Switch to Oral Nicotine

Meier, E., Vogel, R. I., Carmella, S., Paiano, V., Hecht, S. & Hatsukami, D., Apr 1 2017, In : Tobacco Regulatory Science. 3, 2, p. 204-209

Research output: Contribution to journalArticle

2018

The safety evaluation of food flavouring substances: the role of metabolic studies

Smith, R. L., Cohen, S. M., Fukushima, S., Gooderham, N. J., Hecht, S. S., Guengerich, F. P., Rietjens, I. M. C. M., Bastaki, M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Jan 1 2018, In : Toxicology Research. 7, 4, p. 618-646 29 p.

Research output: Contribution to journalReview article

6 Scopus citations
2016
Open Access
19 Scopus citations
2013

Tobacco smoke biomarkers and cancer risk among male smokers in the Shanghai Cohort Study

Hecht, S. S., Murphy, S. E., Stepanov, I., Nelson, H. H. & Yuan, J. M., Jun 28 2013, In : Cancer Letters. 334, 1, p. 34-38 5 p.

Research output: Contribution to journalShort survey

21 Scopus citations
2018
Open Access
8 Scopus citations
2020

Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program

on behalf of program collaborators for ECHO, May 1 2020, In : Journal of Exposure Science and Environmental Epidemiology. 30, 3, p. 397-419 23 p.

Research output: Contribution to journalReview article

1 Scopus citations
2015

GRAS 27 flavoring substances

Cohen, S. M., Fukushima, S., Gooderham, N. J., Hecht, S. S., Marnett, L. J., Rietjens, I. M. C. M., Smith, R. L., Bastaki, M., McGowen, M. M., Harman, C. L. & Taylor, S. V., Aug 2015, Food Technology, 69, 8.

Research output: Contribution to specialist publicationArticle

6 Scopus citations
2018

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Davidsen, J. M., Harman, C. L. & Taylor, S. V., Mar 2018, In : Food and Chemical Toxicology. 113, p. 171-178 8 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2013

Contamination of deconjugation enzymes derived from Helix pomatia with the plant bioactive compounds 3,3'-diindolylmethane, 5-methoxypsoralen, and 8-methoxypsoralen

Ainslie-Waldman, C. E., Simpkins, S. W., Upadhyaya, P., Carmella, S. G., Hecht, S. S. & Trudo, S. P., Sep 20 2013, In : Food and Chemical Toxicology. 62, p. 188-193 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Dietary consumption of black raspberries or their anthocyanin constituents alters innate immune cell trafficking in esophageal cancer

Peiffer, D. S., Wang, L. S., Zimmerman, N. P., Ransom, B. W. S., Carmella, S. G., Kuo, C. T., Chen, J. H., Oshima, K., Huang, Y. W., Hecht, S. S. & Stoner, G. D., Jan 2016, In : Cancer Immunology Research. 4, 1, p. 72-82 11 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations
2018
Open Access
9 Scopus citations
2017

Tobacco, e-cigarettes, and child health

Peterson, L. A. & Hecht, S. S., Apr 1 2017, In : Current Opinion in Pediatrics. 29, 2, p. 225-230 6 p.

Research output: Contribution to journalReview article

Open Access
14 Scopus citations

Biomarkers for Assessment of Chemical Exposures From e-Cigarette Emissions

Hecht, S. S., Jan 1 2017, Analytical Assessment of e-Cigarettes: From Contents to Chemical and Particle Exposure Profiles. Elsevier Inc., p. 59-73 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2020

FEMA GRAS assessment of natural flavor complexes: Cinnamomum and Myroxylon-derived flavoring ingredients

Rietjens, I. M. C. M., Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rosol, T. J., Davidsen, J. M., Harman, C. L., Murray, I. J. & Taylor, S. V., Jan 2020, In : Food and Chemical Toxicology. 135, 110949.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2015
20 Scopus citations

Mercapturic acids derived from the toxicants acrolein and crotonaldehyde in the urine of cigarette smokers from five ethnic groups with differing risks for lung cancer

Park, S. L., Carmella, S. G., Chen, M., Patel, Y., Stram, D. O., Haiman, C. A., Le Marchand, L. & Hecht, S. S., Jun 8 2015, In : PloS one. 10, 6, e0124841.

Research output: Contribution to journalArticle

25 Scopus citations
2011
19 Scopus citations