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  • Bruce R Blazar
2019

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Koehn, B. H., Saha, A., McDonald-Hyman, C., Loschi, M., Thangavelu, G., Ma, L., Zaiken, M., Dysthe, J., Krepps, W., Panthera, J., Hippen, K., Jameson, S. C., Miller, J. S., Cooper, M. A., Farady, C. J., Iwawaki, T., Ting, J. P. Y., Serody, J. S., Murphy, W. J., Hill, G. R. & 5 others, Murray, P. J., Bronte, V., Munn, D. H., Zeiser, R. & Blazar, B. R., Nov 7 2019, In : Blood. 134, 19, p. 1670-1682 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2020

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Thangavelu, G., Du, J., Paz, K. G., Loschi, M., Zaiken, M. C., Flynn, R., Taylor, P. A., Kirchmeier, A. K., Panoskaltsis-Mortari, A., Luznik, L., MacDonald, K. P., Hill, G. R., Maillard, I., Munn, D. H., Serody, J. S., Murphy, W. J., Miklos, D., Cutler, C. S., Koreth, J., Antin, J. H. & 5 others, Soiffer, R. J., Ritz, J., Dahlberg, C., Miller, A. T. & Blazar, B. R., Jan 1 2020, In : Blood. 135, 1, p. 28-40 13 p.

Research output: Contribution to journalArticle

STING differentially regulates experimental GVHD mediated by CD8 versus CD4 T cell subsets

Bader, C. S., Barreras, H., Lightbourn, C. O., Copsel, S. N., Wolf, D., Meng, J., Ahn, J., Komanduri, K. V., Blazar, B. R., Jin, L., Barber, G. N., Roy, S. & Levy, R. B., Jul 15 2020, In : Science Translational Medicine. 12, 552

Research output: Contribution to journalArticle

2018

Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice

Pennell, C. A., Barnum, J. L., McDonald-Hyman, C. S., Panoskaltsis-Mortari, A., Riddle, M. J., Xiong, Z., Loschi, M., Thangavelu, G., Campbell, H. M., Storlie, M. D., Refaeli, Y., Furlan, S. N., Jensen, M. C., Kean, L. S., Miller, J. S., Tolar, J., Osborn, M. J. & Blazar, B. R., Jun 6 2018, In : Molecular Therapy. 26, 6, p. 1423-1434 12 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
2016

Regulatory T cell expressed MyD88 is critical for prolongation of allograft survival

Borges, C. M., Reichenbach, D. K., Kim, B. S., Misra, A., Blazar, B. R. & Turka, L. A., Aug 1 2016, In : Transplant International. 29, 8, p. 930-940 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

Matta, B. M., Reichenbach, D. K., Zhang, X., Mathews, L., Koehn, B. H., Dwyer, G. K., Lott, J. M., Uhl, F. M., Pfeifer, D., Feser, C. J., Smith, M. J., Liu, Q., Zeiser, R., Blazar, B. R. & Turnquist, H. R., Jul 21 2016, In : Blood. 128, 3, p. 427-439 13 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations
2020

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Field, C. S., Baixauli, F., Kyle, R. L., Puleston, D. J., Cameron, A. M., Sanin, D. E., Hippen, K. L., Loschi, M., Thangavelu, G., Corrado, M., Edwards-Hicks, J., Grzes, K. M., Pearce, E. J., Blazar, B. R. & Pearce, E. L., Feb 4 2020, In : Cell Metabolism. 31, 2, p. 422-437.e5

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2019

Cryopreservation timing is a critical process parameter in a thymic regulatory T-cell therapy manufacturing protocol

MacDonald, K. N., Ivison, S., Hippen, K. L., Hoeppli, R. E., Hall, M., Zheng, G., Dijke, I. E., Aklabi, M. A., Freed, D. H., Rebeyka, I., Gandhi, S., West, L. J., Piret, J. M., Blazar, B. R. & Levings, M. K., Dec 2019, In : Cytotherapy. 21, 12, p. 1216-1233 18 p.

Research output: Contribution to journalArticle

2016

Graft Versus Host Disease after Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management

Murali, A. R., Chandra, S., Stewart, Z., Blazar, B. R., Farooq, U., Ince, M. N. & Dunkelberg, J., Dec 1 2016, In : Transplantation. 100, 12, p. 2661-2670 10 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations
2019

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

Wang, Z., Aguilar, E. G., Luna, J. I., Dunai, C., Khuat, L. T., Le, C. T., Mirsoian, A., Minnar, C. M., Stoffel, K. M., Sturgill, I. R., Grossenbacher, S. K., Withers, S. S., Rebhun, R. B., Hartigan-O’Connor, D. J., Méndez-Lagares, G., Tarantal, A. F., Isseroff, R. R., Griffith, T. S., Schalper, K. A., Merleev, A. & 13 others, Saha, A., Maverakis, E., Kelly, K., Aljumaily, R., Ibrahimi, S., Mukherjee, S., Machiorlatti, M., Vesely, S. K., Longo, D. L., Blazar, B. R., Canter, R. J., Murphy, W. J. & Monjazeb, A. M., Jan 1 2019, In : Nature Medicine. 25, 1, p. 141-151 11 p.

Research output: Contribution to journalArticle

Open Access
81 Scopus citations
2017

PD-1 blockade for relapsed lymphoma post-allogeneic hematopoietic cell transplant: High response rate but frequent GVHD

Haverkos, B. M., Abbott, D., Hamadani, M., Armand, P., Flowers, M. E., Merryman, R., Kamdar, M., Kanate, A. S., Saad, A., Mehta, A., Ganguly, S., Fenske, T. S., Hari, P., Lowsky, R., Andritsos, L., Jagasia, M., Bashey, A., Brown, S., Bachanova, V., Stephens, D. & 6 others, Mineishi, S., Nakamura, R., Chen, Y. B., Blazar, B. R., Gutman, J. & Devine, S. M., Jul 13 2017, In : Blood. 130, 2, p. 221-228 8 p.

Research output: Contribution to journalArticle

Open Access
115 Scopus citations
2018

MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice

Wu, Y., Schutt, S., Paz, K., Zhang, M., Flynn, R. P., Bastian, D., Hanief Sofi, M., Nguyen, H., Dai, M., Liu, C., Chang, Y. J., Blazar, B. R. & Yu, X. Z., Apr 26 2018, In : Blood. 131, 17, p. 1974-1986 13 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2016

Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft

Wagner, J. E., Brunstein, C. G., Boitano, A. E., Defor, T. E., McKenna, D., Sumstad, D., Blazar, B. R., Tolar, J., Le, C., Jones, J., Cooke, M. P. & Bleul, C. C., Jan 7 2016, In : Cell Stem Cell. 18, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Open Access
142 Scopus citations
2017

Human in vitro-induced regulatory T cells display Dlgh1dependent and PKC-θ restrained suppressive activity

Zanin-Zhorov, A., Kumari, S., Hippen, K. L., Merkel, S. C., MacMillan, M. L., Blazar, B. R. & Dustin, M. L., Dec 1 2017, In : Scientific reports. 7, 1, 4258.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration

Xiong, Y., Piao, W., Colin Brinkman, C., Li, L., Kulinski, J. M., Olivera, A., Cartier, A., Hla, T., Hippen, K. L., Blazar, B. R., Schwab, S. R. & Bromberg, J. S., Mar 15 2019, In : Science Immunology. 4, 33, eaav1263.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2020

Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs

Osborn, M. J., Newby, G. A., McElroy, A. N., Knipping, F., Nielsen, S. C., Riddle, M. J., Xia, L., Chen, W., Eide, C. R., Webber, B. R., Wandall, H. H., Dabelsteen, S., Blazar, B. R., Liu, D. R. & Tolar, J., Feb 2020, In : Journal of Investigative Dermatology. 140, 2, p. 338-347.e5

Research output: Contribution to journalArticle

4 Scopus citations
2016

Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease

Koreth, J., Kim, H. T., Jones, K. T., Lange, P. B., Reynolds, C. G., Chammas, M. J., Dusenbury, K., Whangbo, J., Nikiforow, S., Alyea, E. P., Armand, P., Cutler, C. S., Ho, V. T., Chen, Y. B., Avigan, D., Blazar, B. R., Antin, J. H., Ritz, J. & Soiffer, R. J., Jul 7 2016, In : Blood. 128, 1, p. 130-137 8 p.

Research output: Contribution to journalArticle

Open Access
79 Scopus citations
2018

Amphiregulin modifies the Minnesota acute graft-versus-host disease risk score: Results from BMT CTN 0302/0802

Holtan, S. G., DeFor, T. E., Panoskaltsis-Mortari, A., Khera, N., Levine, J. E., Flowers, M. E. D., Lee, S. J., Inamoto, Y., Chen, G. L., Mayer, S., Arora, M., Palmer, J., Cutler, C. S., Arai, S., Lazaryan, A., Newell, L. F., Jagasia, M. H., Pusic, I., Wood, W. A., Renteria, A. S. & 17 others, Yanik, G., Hogan, W. J., Hexner, E., Ayuk, F., Holler, E., Bunworasate, U., Efebera, Y. A., Ferrara, J. L. M., Pidala, J., Howard, A., Wu, J., Bolaños-Meade, J., Ho, V., Alousi, A., Blazar, B. R., Weisdorf, D. J. & MacMillan, M. L., Aug 14 2018, In : Blood Advances. 2, 15, p. 1882-1888 7 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2016

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

Leveque-El Mouttie, L., Koyama, M., Le Texier, L., Markey, K. A., Cheong, M., Kuns, R. D., Lineburg, K. E., Teal, B. E., Alexander, K. A., Clouston, A. D., Blazar, B. R., Hill, G. R. & MacDonald, K. P. A., Aug 11 2016, In : Blood. 128, 6, p. 794-804 11 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer

D'Alincourt Salazar, M., Manuel, E. R., Tsai, W., D'Apuzzo, M., Goldstein, L., Blazar, B. R. & Diamond, D. J., Jun 2 2016, In : OncoImmunology. 5, 6, e1160184.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
Open Access
6 Scopus citations
2019

Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion (Nature, (2019), 10.1038/s41586-019-1410-1)

Paczulla, A. M., Rothfelder, K., Raffel, S., Konantz, M., Steinbacher, J., Wang, H., Tandler, C., Mbarga, M., Schaefer, T., Falcone, M., Nievergall, E., Dörfel, D., Hanns, P., Passweg, J. R., Lutz, C., Schwaller, J., Zeiser, R., Blazar, B. R., Caligiuri, M. A., Dirnhofer, S. & 7 others, Lundberg, P., Kanz, L., Quintanilla-Martinez, L., Steinle, A., Trumpp, A., Salih, H. R. & Lengerke, C., Jan 1 2019, In : Nature. 572, 7770, p. E19

Research output: Contribution to journalComment/debate

Open Access
2018

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

Johnson, M. O., Wolf, M. M., Madden, M. Z., Andrejeva, G., Sugiura, A., Contreras, D. C., Maseda, D., Liberti, M. V., Paz, K., Kishton, R. J., Johnson, M. E., de Cubas, A. A., Wu, P., Li, G., Zhang, Y., Newcomb, D. C., Wells, A. D., Restifo, N. P., Rathmell, W. K., Locasale, J. W. & 3 others, Davila, M. L., Blazar, B. R. & Rathmell, J. C., Dec 13 2018, In : Cell. 175, 7, p. 1780-1795.e19

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Chimeric antigen receptor T cell–mediated neurotoxicity in nonhuman primates

Taraseviciute, A., Tkachev, V., Ponce, R., Turtle, C. J., Snyder, J. M., Liggitt, H. D., Myerson, D., Gonzalez-Cuyar, L., Baldessari, A., English, C., Yu, A., Zheng, H., Furlan, S. N., Hunt, D. J., Hoglund, V., Finney, O., Brakke, H., Blazar, B. R., Berger, C., Riddell, S. R. & 3 others, Gardner, R., Kean, L. S. & Jensen, M. C., Jun 2018, In : Cancer discovery. 8, 6, p. 750-763 14 p.

Research output: Contribution to journalArticle

Open Access
61 Scopus citations

Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: Randomized phase II results

Koreth, J., Kim, H. T., Lange, P. B., Poryanda, S. J., Reynolds, C. G., Chamling Rai, S., Armand, P., Cutler, C. S., Ho, V. T., Glotzbecker, B., Yusuf, R., Nikiforow, S., Chen, Y. B., Dey, B., McMasters, M., Ritz, J., Blazar, B. R., Soiffer, R. J., Antin, J. H. & Alyea, E. P., Feb 28 2018, In : Haematologica. 103, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2019
5 Scopus citations
2017

Low EGF in myeloablative allotransplantation: Association with severe acute GvHD in BMT CTN 0402

Holtan, S. G., Newell, L. F., Cutler, C., Verneris, M. R., Defor, T. E., Wu, J., Howard, A., Macmillan, M. L., Antin, J. H., Blazar, B. R., Weisdorf, D. J. & Panoskaltsis-Mortari, A., Sep 1 2017, In : Bone marrow transplantation. 52, 9, p. 1300-1303 4 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2018

Thymic epithelial cell support of thymopoiesis does not require Klotho

Xing, Y., Smith, M. J., Goetz, C. A., McElmurry, R. T., Parker, S. L., Min, D., Hollander, G. A., Weinberg, K. I., Tolar, J., Stefanski, H. E. & Blazar, B. R., Dec 1 2018, In : Journal of Immunology. 201, 11, p. 3320-3328 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Oncogenic JAK2 V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

Prestipino, A., Emhardt, A. J., Aumann, K., O'Sullivan, D., Gorantla, S. P., Duquesne, S., Melchinger, W., Braun, L., Vuckovic, S., Boerries, M., Busch, H., Halbach, S., Pennisi, S., Poggio, T., Apostolova, P., Veratti, P., Hettich, M., Niedermann, G., Bartholomä, M., Shoumariyeh, K. & 29 others, Jutzi, J. S., Wehrle, J., Dierks, C., Becker, H., Schmitt-Graeff, A., Follo, M., Pfeifer, D., Rohr, J., Fuchs, S., Ehl, S., Hartl, F. A., Minguet, S., Miething, C., Heidel, F. H., Kröger, N., Triviai, I., Brummer, T., Finke, J., Illert, A. L., Ruggiero, E., Bonini, C., Duyster, J., Pahl, H. L., Lane, S. W., Hill, G. R., Blazar, B. R., Von Bubnoff, N., Pearce, E. L. & Zeiser, R., Feb 21 2018, In : Science Translational Medicine. 10, 429, eaam7729.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations
2019
1 Scopus citations
2016
Open Access
2019
Open Access
1 Scopus citations
2016

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease

Le Texier, L., Lineburg, K. E., Cao, B., McDonald-Hyman, C., Leveque-El Mouttie, L., Nicholls, J., Melino, M., Nalkurthi, B. C., Alexander, K. A., Teal, B., Blake, S. J., Souza-Fonseca-Guimaraes, F., Engwerda, C. R., Kuns, R. D., Lane, S. W., Teng, M., Teh, C., Gray, D., Clouston, A. D., Nilsson, S. K. & 3 others, Blazar, B. R., Hill, G. R. & MacDonald, K. P. A., Sep 22 2016, In : JCI insight. 1, 15, p. e86850

Research output: Contribution to journalArticle

2020

IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer

Furlan, S. N., Singh, K., Lopez, C., Tkachev, V., Hunt, D. J., Hibbard, J., Betz, K. M., Blazar, B. R., Trapnell, C. & Kean, L. S., Apr 28 2020, In : Blood Advances. 4, 8, p. 1594-1605 12 p.

Research output: Contribution to journalArticle

Open Access

Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

Blazar, B. R., Hill, G. R. & Murphy, W. J., Aug 1 2020, In : Nature Reviews Clinical Oncology. 17, 8, p. 475-492 18 p.

Research output: Contribution to journalReview article

Validation of Minnesota acute graft-versus-host disease Risk Score

MacMillan, M. L., DeFor, T. E., Holtan, S. G., Rashidi, A., Blazar, B. R. & Weisdorf, D. J., Jan 31 2020, In : Haematologica. 105, 2, p. 519-524 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Notch signaling mediated by delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice

Radojcic, V., Paz, K., Chung, J., Du, J., Perkey, E. T., Flynn, R., Ivcevic, S., Zaiken, M., Friedman, A., Yan, M., Pletneva, M. A., Sarantopoulos, S., Siebel, C. W., Blazar, B. R. & Maillard, I., Nov 15 2018, In : Blood. 132, 20, p. 2188-2200 13 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2020

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth

Phan, T., Nguyen, V. H., D’Alincourt, M. S., Manuel, E. R., Kaltcheva, T., Tsai, W., Blazar, B. R., Diamond, D. J. & Melstrom, L. G., Apr 1 2020, In : Cancer gene therapy. 27, 3-4, p. 235-245 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination

Ni, X., Kou, W., Gu, J., Wei, P., Wu, X., Peng, H., Tao, J., Yan, W., Yang, X., Lebid, A., Park, B. V., Chen, Z., Tian, Y., Fu, J., Newman, S., Wang, X., Shen, H., Li, B., Blazar, B. R., Wang, X. & 3 others, Barbi, J., Pan, F. & Lu, L., May 2 2019, In : EMBO Journal. 38, 9, e99766.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2018

A critical role for donor-derived IL-22 in cutaneous chronic GVHD

Gartlan, K. H., Bommiasamy, H., Paz, K., Wilkinson, A. N., Owen, M., Reichenbach, D. K., Banovic, T., Wehner, K., Buchanan, F., Varelias, A., Kuns, R. D., Chang, K., Fedoriw, Y., Shea, T., Coghill, J., Zaiken, M., Plank, M. W., Foster, P. S., Clouston, A. D., Blazar, B. R. & 2 others, Serody, J. S. & Hill, G. R., Apr 2018, In : American Journal of Transplantation. 18, 4, p. 810-820 11 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

Mathew, N. R., Baumgartner, F., Braun, L., O'Sullivan, D., Thomas, S., Waterhouse, M., Müller, T. A., Hanke, K., Taromi, S., Apostolova, P., Illert, A. L., Melchinger, W., Duquesne, S., Schmitt-Graeff, A., Osswald, L., Yan, K. L., Weber, A., Tugues, S., Spath, S., Pfeifer, D. & 110 others, Follo, M., Claus, R., Lübbert, M., Rummelt, C., Bertz, H., Wäsch, R., Haag, J., Schmidts, A., Schultheiss, M., Bettinger, D., Thimme, R., Ullrich, E., Tanriver, Y., Vuong, G. L., Arnold, R., Hemmati, P., Wolf, D., Ditschkowski, M., Jilg, C., Wilhelm, K., Leiber, C., Gerull, S., Halter, J., Lengerke, C., Pabst, T., Schroeder, T., Kobbe, G., Rösler, W., Doostkam, S., Meckel, S., Stabla, K., Metzelder, S. K., Halbach, S., Brummer, T., Hu, Z., Dengjel, J., Hackanson, B., Schmid, C., Holtick, U., Scheid, C., Spyridonidis, A., Stölzel, F., Ordemann, R., Müller, L. P., Sicre-De-Fontbrune, F., Ihorst, G., Kuball, J., Ehlert, J. E., Feger, D., Wagner, E. M., Cahn, J. Y., Schnell, J., Kuchenbauer, F., Bunjes, D., Chakraverty, R., Richardson, S., Gill, S., Kröger, N., Ayuk, F., Vago, L., Ciceri, F., Müller, A. M., Kondo, T., Teshima, T., Klaeger, S., Kuster, B., Kim, D. H., Weisdorf, D., Van Der Velden, W., Dörfel, D., Bethge, W., Hilgendorf, I., Hochhaus, A., Andrieux, G., Börries, M., Busch, H., Magenau, J., Reddy, P., Labopin, M., Antin, J. H., Henden, A. S., Hill, G. R., Kennedy, G. A., Bar, M., Sarma, A., McLornan, D., Mufti, G., Oran, B., Rezvani, K., Shah, O., Negrin, R. S., Nagler, A., Prinz, M., Burchert, A., Neubauer, A., Beelen, D., Mackensen, A., Von Bubnoff, N., Herr, W., Becher, B., Socié, G., Caligiuri, M. A., Ruggiero, E., Bonini, C., Häcker, G., Duyster, J., Finke, J., Pearce, E., Blazar, B. R. & Zeiser, R., Mar 1 2018, In : Nature Medicine. 24, 3, p. 282-291 10 p.

Research output: Contribution to journalArticle

Open Access
62 Scopus citations
2017

The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease

Cooke, K. R., Luznik, L., Sarantopoulos, S., Hakim, F. T., Jagasia, M., Fowler, D. H., van den Brink, M. R. M., Hansen, J. A., Parkman, R., Miklos, D. B., Martin, P. J., Paczesny, S., Vogelsang, G., Pavletic, S., Ritz, J., Schultz, K. R. & Blazar, B. R., Feb 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 2, p. 211-234 24 p.

Research output: Contribution to journalReview article

Open Access
101 Scopus citations

Chronic graft-versus-host disease: Biological insights from preclinical and clinical studies

MacDonald, K. P. A., Hill, G. R. & Blazar, B. R., Jan 5 2017, In : Blood. 129, 1, p. 13-21 9 p.

Research output: Contribution to journalReview article

Open Access
85 Scopus citations
2016

Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer

Mall, C., Sckisel, G. D., Proia, D. A., Mirsoian, A., Grossenbacher, S. K., Pai, C. C. S., Chen, M., Monjazeb, A. M., Kelly, K., Blazar, B. R. & Murphy, W. J., Feb 1 2016, In : OncoImmunology. 5, 2

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Modulation of immune checkpoints and graft-versus-leukemia in allogeneic transplants by antagonizing vasoactive intestinal peptide signaling

Li, J. M., Petersen, C. T., Li, J. X., Panjwani, R., Chandra, D. J., Giver, C. R., Blazar, B. R. & Waller, E. K., Dec 1 2016, In : Cancer Research. 76, 23, p. 6802-6815 14 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2019

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program

Hou, S., Clement, R. L., Diallo, A., Blazar, B. R., Rudensky, A. Y., Sharpe, A. H. & Sage, P. T., Mar 1 2019, In : Journal of Experimental Medicine. 216, 3, p. 605-620 16 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
2016

MiR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

Lu, Y., Hippen, K. L., Lemire, A. L., Gu, J., Wang, W., Ni, X., Ranganathan, P., Levine, B. L., Riley, J. L., June, C. H., Turka, L. A., Munn, D. H., Garzon, R., Lu, L. & Blazar, B. R., Sep 8 2016, In : Blood. 128, 10, p. 1424-1435 12 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
2018

C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans

Verghese, D. A., Chun, N., Paz, K., Fribourg, M., Woodruff, T. M., Flynn, R., Hu, Y., Xiong, H., Zhang, W., Yi, Z., Du, J., Blazar, B. R. & Heeger, P. S., Dec 20 2018, In : JCI Insight. 3, 24

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Open Access
4 Scopus citations
2020

β2-Adrenergic receptor activation on donor cells ameliorates acute GvHD

Mohammadpour, H., Sarow, J. L., MacDonald, C. R., Chen, G. L., Qiu, J., Sharma, U. C., Cao, X., Herr, M. M., Hahn, T. E., Blazar, B. R., Repasky, E. A. & McCarthy, P. L., Jun 18 2020, In : JCI Insight. 5, 12

Research output: Contribution to journalArticle

Open Access

Tissue mast cell counts may be associated with decreased severity of gastrointestinal acute GVHD and nonrelapse mortality

Ustun, C., DeFor, T. E., Karadag, F. K., Yun, H. D., Nathan, S., Brunstein, C. G., Blazar, B. R., Weisdorf, D. J., Holtan, S. G. & Amin, K., May 26 2020, In : Blood Advances. 4, 10, p. 2317-2324 8 p.

Research output: Contribution to journalArticle

Open Access