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  • Stephen S Hecht
2016
Open Access
13 Scopus citations
Open Access
10 Scopus citations

Analytical Assessment of e-Cigarettes: From Contents to Chemical and Particle Exposure Profiles

Farsalinos, K. E., Gillman, I. G., Hecht, S. S., Polosa, R. & Thornburg, J., Nov 14 2016, Elsevier Inc. 150 p.

Research output: Book/ReportBook

5 Scopus citations

A randomized controlled trial of progressively reduced nicotine content cigarettes on smoking behaviors, biomarkers of exposure, and subjective ratings

Mercincavage, M., Souprountchouk, V., Tang, K. Z., Dumont, R. L., Wileyto, E. P., Carmella, S. G., Hecht, S. S. & Strasser, A. A., Jul 2016, In : Cancer Epidemiology Biomarkers and Prevention. 25, 7, p. 1125-1133 9 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Benzene uptake and glutathione S-transferase T1 status as determinants of S-phenylmercapturic acid in cigarette smokers in the multiethnic cohort

Haiman, C. A., Patel, Y. M., Stram, D. O., Carmella, S. G., Chen, M., Wilkens, L. R., Le Marchand, L. & Hecht, S. S., Mar 2016, In : PloS one. 11, 3, e0150641.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
Open Access

Clinical trial of 2-phenethyl isothiocyanate as an inhibitor of metabolic activation of a tobacco-specific lung carcinogen in cigarette smokers

Yuan, J. M., Stepanov, I., Murphy, S. E., Wang, R., Allen, S., Jensen, J., Strayer, L., Adams-Haduch, J., Upadhyaya, P., Le, C., Kurzer, M. S., Nelson, H. H., Yu, M. C., Hatsukami, D. & Hecht, S. S., May 2016, In : Cancer Prevention Research. 9, 5, p. 396-405 10 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Dietary consumption of black raspberries or their anthocyanin constituents alters innate immune cell trafficking in esophageal cancer

Peiffer, D. S., Wang, L. S., Zimmerman, N. P., Ransom, B. W. S., Carmella, S. G., Kuo, C. T., Chen, J. H., Oshima, K., Huang, Y. W., Hecht, S. S. & Stoner, G. D., Jan 2016, In : Cancer Immunology Research. 4, 1, p. 72-82 11 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification

Narayanapillai, S. C., Von Weymarn, L. B., Carmella, S. G., Leitzman, P., Paladino, J., Upadhyaya, P., Hecht, S. S., Murphy, S. E. & Xing, C., Mar 1 2016, In : Drug Metabolism and Disposition. 44, 3, p. 422-427 6 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

DNA Adduct Formation from Metabolic 5′-Hydroxylation of the Tobacco-Specific Carcinogen N′-Nitrosonornicotine in Human Enzyme Systems and in Rats

Zarth, A. T., Upadhyaya, P., Yang, J. & Hecht, S. S., Mar 21 2016, In : Chemical research in toxicology. 29, 3, p. 380-389 10 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Evaluation of Nitrosamide Formation in the Cytochrome P450-Mediated Metabolism of Tobacco-Specific Nitrosamines

Carlson, E. S., Upadhyaya, P. & Hecht, S. S., Dec 19 2016, In : Chemical research in toxicology. 29, 12, p. 2194-2205 12 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
Open Access
50 Scopus citations

FEMA expert panel review of p-mentha-1,8-dien-7-al genotoxicity testing results

Cohen, S. M., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Smith, R. L., Bastaki, M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Dec 1 2016, In : Food and Chemical Toxicology. 98, p. 201-209 9 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations
Open Access
19 Scopus citations

Harnessing the power of cruciferous vegetables: Developing a biomarker for brassica vegetable consumption using urinary 3,3'-diindolylmethane

Fujioka, N., Ransom, B. W., Carmella, S. G., Upadhyaya, P., Lindgren, B. R., Roper-Batker, A., Hatsukami, D. K., Fritz, V. A., Rohwer, C. & Hecht, S. S., Oct 2016, In : Cancer Prevention Research. 9, 10, p. 788-793 6 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis

Smith, M. T., Guyton, K. Z., Gibbons, C. F., Fritz, J. M., Portier, C. J., Rusyn, I., DeMarini, D. M., Caldwell, J. C., Kavlock, R. J., Lambert, P. F., Hecht, S. S., Bucher, J. R., Stewart, B. W., Baan, R. A., Cogliano, V. J. & Straif, K., Jun 2016, In : Environmental health perspectives. 124, 6, p. 713-721 9 p.

Research output: Contribution to journalReview article

169 Scopus citations

Metabolites of the polycyclic aromatic hydrocarbon phenanthrene in the urine of cigarette smokers from five ethnic groups with differing risks for lung cancer

Patel, Y. M., Park, S. L., Carmella, S. G., Paiano, V., Olvera, N., Stram, D. O., Haiman, C. A., Le Marchand, L. & Hecht, S. S., Jun 1 2016, In : PloS one. 11, 6, e0156203.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Randomised clinical trial of snus versus medicinal nicotine among smokers interested in product switching

Hatsukami, D. K., Severson, H., Anderson, A., Vogel, R. I., Jensen, J., Broadbent, B., Murphy, S. E., Carmella, S. G. & Hecht, S. S., May 2016, In : Tobacco control. 25, 3, p. 267-274 8 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg

Fujioka, N., Fritz, V., Upadhyaya, P., Kassie, F. & Hecht, S. S., Jun 1 2016, In : Molecular Nutrition and Food Research. 60, 6, p. 1228-1238 11 p.

Research output: Contribution to journalReview article

24 Scopus citations

Tobacco-specific N-nitrosamines and polycyclic aromatic hydrocarbons in cigarettes smoked by the participants of the Shanghai Cohort Study

Yershova, K., Yuan, J. M., Wang, R., Valentin, L., Watson, C., Gao, Y. T., Hecht, S. S. & Stepanov, I., Sep 15 2016, In : International Journal of Cancer. 139, 6, p. 1261-1269 9 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
Open Access
3 Scopus citations
2018

Acrolein exposure in hookah smokers and non-smokers exposed to hookah tobacco secondhand smoke: Implications for regulating hookah tobacco products

Kassem, N. O. F., Kassem, N. O., Liles, S., Zarth, A. T., Jackson, S. R., Daffa, R. M., Chatfield, D. A., Carmella, S. G., Hecht, S. S. & Hovell, M. F., Mar 6 2018, In : Nicotine and Tobacco Research. 20, 4, p. 492-501 10 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
Open Access
8 Scopus citations

A New Editorial Team for CRT

Hecht, S. S., Jan 16 2018, In : Chemical research in toxicology. 31, 1, 1 p.

Research output: Contribution to journalEditorial

Open Access

Carcinogenic Effects of Cigarette Smoke on the Respiratory Tract

Peterson, L. A., Urban, A. M. & Hecht, S. S., Jan 1 2018, Respiratory Toxicology. Elsevier Inc., Vol. 15-15. p. 228-253 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Comparison of Nicotine and Toxicant Exposure in Users of Electronic Cigarettes and Combustible Cigarettes

Goniewicz, M. L., Smith, D. M., Edwards, K. C., Blount, B. C., Caldwell, K. L., Feng, J., Wang, L., Christensen, C., Ambrose, B., Borek, N., van Bemmel, D., Konkel, K., Erives, G., Stanton, C. A., Lambert, E., Kimmel, H. L., Hatsukami, D., Hecht, S. S., Niaura, R. S., Travers, M. & 2 others, Lawrence, C. & Hyland, A. J., Dec 7 2018, In : JAMA Network Open. 1, 8, p. e185937

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Effect of immediate vs gradual reduction in nicotine content of cigarettes on biomarkers of smoke exposure a randomized clinical trial

Hatsukami, D. K., Luo, X., Jensen, J. A., Al'Absi, M., Allen, S. S., Carmella, S. G., Chen, M., Cinciripini, P. M., Denlinger-Apte, R., Drobes, D. J., Koopmeiners, J. S., Lane, T., Le, C. T., Leischow, S., Luo, K., Joseph McClernon, F., Murphy, S. E., Paiano, V., Robinson, J. D., Severson, H. & 8 others, Sipe, C., Strasser, A. A., Strayer, L. G., Tang, M. K., Vandrey, R., Hecht, S. S., Benowitz, N. L. & Donny, E. C., Sep 4 2018, In : JAMA - Journal of the American Medical Association. 320, 9, p. 880-891 12 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
Open Access
Open Access
9 Scopus citations
Open Access
1 Scopus citations
Open Access
10 Scopus citations

Relationship of the oxidative damage biomarker 8-epiprostaglandin F to risk of lung cancer development in the Shanghai Cohort Study

Yuan, J. M., Carmella, S. G., Wang, R., Tan, Y. T., Adams-Haduch, J., Gao, Y. T. & Hecht, S. S., Jul 3 2018, In : Carcinogenesis. 39, 7, p. 948-954 7 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

The safety evaluation of food flavouring substances: the role of metabolic studies

Smith, R. L., Cohen, S. M., Fukushima, S., Gooderham, N. J., Hecht, S. S., Guengerich, F. P., Rietjens, I. M. C. M., Bastaki, M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Jan 1 2018, In : Toxicology Research. 7, 4, p. 618-646 29 p.

Research output: Contribution to journalReview article

6 Scopus citations

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Davidsen, J. M., Harman, C. L. & Taylor, S. V., Mar 2018, In : Food and Chemical Toxicology. 113, p. 171-178 8 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2019
Open Access
8 Scopus citations

Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers

St.Helen, G., Benowitz, N. L., Ko, J., Jacob, P., Gregorich, S. E., Pérez-Stable, E. J., Murphy, S. E., Hecht, S. S., Hatsukami, D. K. & Donny, E. C., Jan 1 2019, In : Journal of Exposure Science and Environmental Epidemiology.

Research output: Contribution to journalArticle

1 Scopus citations

Dose-dependent detoxication of the airborne pollutant benzene in a randomized trial of broccoli sprout beverage in Qidong, China

Chen, J. G., Johnson, J., Egner, P., Ng, D., Zhu, J., Wang, J. B., Xue, X. F., Sun, Y., Zhang, Y. H., Lu, L. L., Chen, Y. S., Wu, Y., Zhu, Y. R., Carmella, S., Hecht, S., Jacobson, L., Muñoz, A., Kensler, K., Rule, A., Fahey, J. & 2 others, Kensler, T. & Groopman, J., Sep 1 2019, In : American Journal of Clinical Nutrition. 110, 3, p. 675-684 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effects of 6-Week Use of Very Low Nicotine Content Cigarettes in Smokers With Serious Mental Illness

Tidey, J. W., Colby, S. M., Denlinger-Apte, R. L., Goodwin, C., Cioe, P. A., Cassidy, R. N., Swift, R. M., Lindgren, B. R., Rubin, N., Murphy, S. E., Hecht, S. S., Hatsukami, D. K. & Donny, E. C., Dec 23 2019, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 21, 1, p. S38-S45

Research output: Contribution to journalArticle

Open Access

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage

McElroy, J. P., Carmella, S. G., Heskin, A. K., Tang, M. K., Murphy, S. E., Reisinger, S. A., Jensen, J. A., Hatsukami, D. K., Hecht, S. S. & Shields, P. G., Jan 1 2019, In : PloS one. 14, 6, e0218386.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects

Hatsukami, D. K., Luo, X., Heskin, A. K., Tang, M. K., Carmella, S. G., Jensen, J., Robinson, J. D., Vandrey, R., Drobes, D. J., Strasser, A. A., al'Absi, M., Leischow, S., Cinciripini, P. M., Koopmeiners, J., Ikuemonisan, J., Benowitz, N. L., Donny, E. C. & Hecht, S. S., Oct 1 2019, In : Addiction. 114, 10, p. 1824-1833 10 p.

Research output: Contribution to journalArticle

FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Bastaki, M., Davidsen, J. M., Harman, C. L., McGowen, M. & Taylor, S. V., Feb 2019, In : Food and Chemical Toxicology. 124, p. 192-218 27 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein

Chen, M., Carmella, S. G., Sipe, C., Jensen, J., Luo, X., Le, C. T., Murphy, S. E., Benowitz, N. L., Joseph McClernon, F., Vandrey, R., Allen, S. S., Denlinger-Apte, R., Cinciripini, P. M., Strasser, A. A., Al’Absi, M., Robinson, J. D., Donny, E. C., Hatsukami, D. & Hecht, S. S., Jan 2019, In : PloS one. 14, 1, e0210104.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation

Carmella, S. G., Heskin, A. K., Tang, M. K., Jensen, J., Luo, X., Le, C. T., Murphy, S. E., Benowitz, N. L., Joseph McClernon, F., Vandrey, R., Allen, S. S., Denlinger-Apte, R., Cinciripini, P. M., Strasser, A. A., Al’Absi, M., Robinson, J. D., Donny, E. C., Hatsukami, D. K. & Hecht, S. S., Apr 2019, In : PloS one. 14, 4, e0215853.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N′-Nitrosonornicotine

Li, Y., Ma, B., Cao, Q., Balbo, S., Zhao, L., Upadhyaya, P. & Hecht, S. S., Apr 15 2019, In : Chemical research in toxicology. 32, 4, p. 773-783 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
1 Scopus citations

Oral Health Effects of Combusted and Smokeless Tobacco Products

Tomar, S. L., Hecht, S. S., Jaspers, I., Gregory, R. L. & Stepanov, I., Oct 1 2019, In : Advances in dental research. 30, 1, p. 4-10 7 p.

Research output: Contribution to journalReview article

3 Scopus citations

Prediagnostic levels of urinary 8-epi-prostaglandin F and prostaglandin E2 metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma

Yuan, J. M., Grouls, M., Carmella, S. G., Wang, R., Heskin, A., Jiang, Y., Tan, Y. T., Adams-Haduch, J., Gao, Y. T. & Hecht, S. S., Aug 22 2019, In : Carcinogenesis. 40, 8, p. 989-997 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update

Stram, D. O., Park, S. L., Haiman, C. A., Murphy, S. E., Patel, Y., Hecht, S. S. & Le Marchand, L., Aug 1 2019, In : Journal of the National Cancer Institute. 111, 8, p. 811-819 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Recent studies on DNA adducts resulting from human exposure to tobacco smoke

Ma, B., Stepanov, I. & Hecht, S. S., Jan 1 2019, In : Toxics. 7, 1, 16.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

Urinary concentrations of monohydroxylated polycyclic aromatic hydrocarbons in adults from the U.S. Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)

Wang, Y., Wong, L. Y., Meng, L., Pittman, E. N., Trinidad, D. A., Hubbard, K. L., Etheredge, A., Del Valle-Pinero, A. Y., Zamoiski, R., van Bemmel, D. M., Borek, N., Patel, V., Kimmel, H. L., Conway, K. P., Lawrence, C., Edwards, K. C., Hyland, A., Goniewicz, M. L., Hatsukami, D., Hecht, S. S. & 1 others, Calafat, A. M., Feb 2019, In : Environment International. 123, p. 201-208 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations