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  • Stephen S Hecht
2018
Open Access
10 Scopus citations

Relationship of the oxidative damage biomarker 8-epiprostaglandin F to risk of lung cancer development in the Shanghai Cohort Study

Yuan, J. M., Carmella, S. G., Wang, R., Tan, Y. T., Adams-Haduch, J., Gao, Y. T. & Hecht, S. S., Jul 3 2018, In : Carcinogenesis. 39, 7, p. 948-954 7 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

The safety evaluation of food flavouring substances: the role of metabolic studies

Smith, R. L., Cohen, S. M., Fukushima, S., Gooderham, N. J., Hecht, S. S., Guengerich, F. P., Rietjens, I. M. C. M., Bastaki, M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Jan 1 2018, In : Toxicology Research. 7, 4, p. 618-646 29 p.

Research output: Contribution to journalReview article

6 Scopus citations

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Davidsen, J. M., Harman, C. L. & Taylor, S. V., Mar 2018, In : Food and Chemical Toxicology. 113, p. 171-178 8 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2019
Open Access
8 Scopus citations

Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers

St.Helen, G., Benowitz, N. L., Ko, J., Jacob, P., Gregorich, S. E., Pérez-Stable, E. J., Murphy, S. E., Hecht, S. S., Hatsukami, D. K. & Donny, E. C., Jan 1 2019, In : Journal of Exposure Science and Environmental Epidemiology.

Research output: Contribution to journalArticle

1 Scopus citations

Dose-dependent detoxication of the airborne pollutant benzene in a randomized trial of broccoli sprout beverage in Qidong, China

Chen, J. G., Johnson, J., Egner, P., Ng, D., Zhu, J., Wang, J. B., Xue, X. F., Sun, Y., Zhang, Y. H., Lu, L. L., Chen, Y. S., Wu, Y., Zhu, Y. R., Carmella, S., Hecht, S., Jacobson, L., Muñoz, A., Kensler, K., Rule, A., Fahey, J. & 2 others, Kensler, T. & Groopman, J., Sep 1 2019, In : American Journal of Clinical Nutrition. 110, 3, p. 675-684 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effects of 6-Week Use of Very Low Nicotine Content Cigarettes in Smokers With Serious Mental Illness

Tidey, J. W., Colby, S. M., Denlinger-Apte, R. L., Goodwin, C., Cioe, P. A., Cassidy, R. N., Swift, R. M., Lindgren, B. R., Rubin, N., Murphy, S. E., Hecht, S. S., Hatsukami, D. K. & Donny, E. C., Dec 23 2019, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 21, 1, p. S38-S45

Research output: Contribution to journalArticle

Open Access

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage

McElroy, J. P., Carmella, S. G., Heskin, A. K., Tang, M. K., Murphy, S. E., Reisinger, S. A., Jensen, J. A., Hatsukami, D. K., Hecht, S. S. & Shields, P. G., 2019, In : PloS one. 14, 6, e0218386.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects

Hatsukami, D. K., Luo, X., Heskin, A. K., Tang, M. K., Carmella, S. G., Jensen, J., Robinson, J. D., Vandrey, R., Drobes, D. J., Strasser, A. A., al'Absi, M., Leischow, S., Cinciripini, P. M., Koopmeiners, J., Ikuemonisan, J., Benowitz, N. L., Donny, E. C. & Hecht, S. S., Oct 1 2019, In : Addiction. 114, 10, p. 1824-1833 10 p.

Research output: Contribution to journalArticle

FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Bastaki, M., Davidsen, J. M., Harman, C. L., McGowen, M. & Taylor, S. V., Feb 2019, In : Food and Chemical Toxicology. 124, p. 192-218 27 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein

Chen, M., Carmella, S. G., Sipe, C., Jensen, J., Luo, X., Le, C. T., Murphy, S. E., Benowitz, N. L., Joseph McClernon, F., Vandrey, R., Allen, S. S., Denlinger-Apte, R., Cinciripini, P. M., Strasser, A. A., Al’Absi, M., Robinson, J. D., Donny, E. C., Hatsukami, D. & Hecht, S. S., Jan 2019, In : PloS one. 14, 1, e0210104.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation

Carmella, S. G., Heskin, A. K., Tang, M. K., Jensen, J., Luo, X., Le, C. T., Murphy, S. E., Benowitz, N. L., Joseph McClernon, F., Vandrey, R., Allen, S. S., Denlinger-Apte, R., Cinciripini, P. M., Strasser, A. A., Al’Absi, M., Robinson, J. D., Donny, E. C., Hatsukami, D. K. & Hecht, S. S., Apr 2019, In : PloS one. 14, 4, e0215853.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N′-Nitrosonornicotine

Li, Y., Ma, B., Cao, Q., Balbo, S., Zhao, L., Upadhyaya, P. & Hecht, S. S., Apr 15 2019, In : Chemical research in toxicology. 32, 4, p. 773-783 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
1 Scopus citations

Oral Health Effects of Combusted and Smokeless Tobacco Products

Tomar, S. L., Hecht, S. S., Jaspers, I., Gregory, R. L. & Stepanov, I., Oct 1 2019, In : Advances in dental research. 30, 1, p. 4-10 7 p.

Research output: Contribution to journalReview article

3 Scopus citations

Prediagnostic levels of urinary 8-epi-prostaglandin F and prostaglandin E2 metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma

Yuan, J. M., Grouls, M., Carmella, S. G., Wang, R., Heskin, A., Jiang, Y., Tan, Y. T., Adams-Haduch, J., Gao, Y. T. & Hecht, S. S., Aug 22 2019, In : Carcinogenesis. 40, 8, p. 989-997 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update

Stram, D. O., Park, S. L., Haiman, C. A., Murphy, S. E., Patel, Y., Hecht, S. S. & Le Marchand, L., Aug 1 2019, In : Journal of the National Cancer Institute. 111, 8, p. 811-819 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Recent studies on DNA adducts resulting from human exposure to tobacco smoke

Ma, B., Stepanov, I. & Hecht, S. S., Jan 1 2019, In : Toxics. 7, 1, 16.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations

Urinary concentrations of monohydroxylated polycyclic aromatic hydrocarbons in adults from the U.S. Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)

Wang, Y., Wong, L. Y., Meng, L., Pittman, E. N., Trinidad, D. A., Hubbard, K. L., Etheredge, A., Del Valle-Pinero, A. Y., Zamoiski, R., van Bemmel, D. M., Borek, N., Patel, V., Kimmel, H. L., Conway, K. P., Lawrence, C., Edwards, K. C., Hyland, A., Goniewicz, M. L., Hatsukami, D., Hecht, S. S. & 1 others, Calafat, A. M., Feb 2019, In : Environment International. 123, p. 201-208 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2020

A Randomized Clinical Trial of Snus Examining the Effect of Complete Versus Partial Cigarette Substitution on Smoking-Related Behaviors, and Biomarkers of Exposure

Meier, E., Lindgren, B. R., Anderson, A., Reisinger, S. A., Norton, K. J., Jensen, J., Strayer, L., Dick, L., Tang, M. K., Chen, M., Carmella, S. G., Hecht, S. S., Murphy, S. E., Yang, J., Stepanov, I., O'Connor, R. J., Shields, P. G. & Hatsukami, D. K., Apr 17 2020, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 22, 4, p. 473-481 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Biochemical Verification of Tobacco Use and Abstinence: 2019 Update

Benowitz, N. L., Bernert, J. T., Foulds, J., Hecht, S. S., Jacob, P., Jarvis, M. J., Joseph, A., Oncken, C. & Piper, M. E., Jun 12 2020, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 22, 7, p. 1086-1097 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Biomarkers of exposure among adult smokeless tobacco users in the population assessment of Tobacco and health study (WAVE 1, 2013-2014)

Cheng, Y. C., Reyes-Guzman, C. M., Christensen, C. H., Rostron, B. L., Edwards, K. C., Wang, L., Feng, J., Jarrett, J. M., Ward, C. D., Xia, B., Kimmel, H. L., Conway, K., Leggett, C., Taylor, K., Lawrence, C., Niaura, R., Travers, M. J., Hyland, A., Hecht, S. S., Hatsukami, D. K. & 4 others, Goniewicz, M. L., Borek, N., Blount, B. C. & van Bemmel, D. M., Jan 1 2020, In : Cancer Epidemiology Biomarkers and Prevention. 29, 3, p. 659-667 9 p.

Research output: Contribution to journalReview article

Effects of 2-phenethyl isothiocyanate on metabolism of 1,3-butadiene in smokers

Boldry, E. J., Yuan, J. M., Carmella, S. G., Wang, R., Tessier, K., Hatsukami, D. K., Hecht, S. S. & Tretyakova, N. Y., Jan 1 2020, In : Cancer Prevention Research. 13, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

FEMA GRAS assessment of natural flavor complexes: Mint, buchu, dill and caraway derived flavoring ingredients

Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Bastaki, M., Davidsen, J. M., Harman, C. L., McGowen, M. M. & Taylor, S. V., Jan 2020, In : Food and Chemical Toxicology. 135, 110870.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

FEMA GRAS assessment of natural flavor complexes: Cinnamomum and Myroxylon-derived flavoring ingredients

Rietjens, I. M. C. M., Cohen, S. M., Eisenbrand, G., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rosol, T. J., Davidsen, J. M., Harman, C. L., Murray, I. J. & Taylor, S. V., Jan 2020, In : Food and Chemical Toxicology. 135, 110949.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program

on behalf of program collaborators for ECHO, May 1 2020, In : Journal of Exposure Science and Environmental Epidemiology. 30, 3, p. 397-419 23 p.

Research output: Contribution to journalReview article

1 Scopus citations

Relationships between the nicotine metabolite ratio and a panel of exposure and effect biomarkers: Findings from two studies of U.S. commercial cigarette smokers

Carroll, D. M., Murphy, S. E., Benowitz, N. L., Strasser, A. A., Kotlyar, M., Hecht, S. S., Carmella, S. G., McClernon, F. J., Pacek, L. R., Dermody, S. S., Vandrey, R. G., Donny, E. C. & Hatsukami, D. K., 2020, In : Cancer Epidemiology Biomarkers and Prevention. 29, 4, p. 871-879 9 p.

Research output: Contribution to journalArticle

Open Access

The Impact of One-week Dietary Supplementation with Kava on Biomarkers of Tobacco Use and Nitrosamine-based Carcinogenesis Risk among Active Smokers

Wang, Y., Narayanapillai, S. C., Tessier, K. M., Strayer, L. G., Upadhyaya, P., Hu, Q., Kingston, R., Salloum, R. G., Lu, J., Hecht, S. S., Hatsukami, D. K., Fujioka, N. & Xing, C., May 1 2020, In : Cancer prevention research (Philadelphia, Pa.). 13, 5, p. 483-492 10 p.

Research output: Contribution to journalArticle

The safety evaluation of food flavoring substances: the role of genotoxicity studies

Gooderham, N. J., Cohen, S. M., Eisenbrand, G., Fukushima, S., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Rosol, T. J., Bastaki, M., Linman, M. J. & Taylor, S. V., Jan 2 2020, In : Critical Reviews in Toxicology. 50, 1, p. 1-27 27 p.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations