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Author

  • Perry B Hackett
2011

Characterization of the human artemis promoter by heterologous gene expression in vitro and in vivo

Multhaup, M. M., Gurram, S., Podetz-Pedersen, K. M., Karlen, A. D., Swanson, D. L., Somia, N. V., Hackett, P. B., Cowan, M. J. & Mc Ivor, R. S., Oct 1 2011, In : DNA and Cell Biology. 30, 10, p. 751-761 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Efficacy and safety of sleeping beauty transposon-mediated gene transfer in preclinical animal studies

Hackett, P. B., Aronovich, E. L., Hunter, D., Urness, M., Bell, J. B., Kass, S. J., Cooper, L. J. N. & McIvor, S., Oct 2011, In : Current gene therapy. 11, 5, p. 341-349 9 p.

Research output: Contribution to journalArticle

43 Scopus citations

Human hepatic stellate cell line (LX-2) exhibits characteristics of bone marrow-derived mesenchymal stem cells

Castilho-Fernandes, A., de Almeida, D. C., Fontes, A. M., Melo, F. U. F., Picanço-Castro, V., Freitas, M. C., Orellana, M. D., Palma, P. V. B., Hackett, P. B., Friedman, S. L. & Covas, D. T., Dec 1 2011, In : Experimental and Molecular Pathology. 91, 3, p. 664-672 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Sleeping Beauty-mediated correction of Fanconi anemia type C

Hyland, K. A., Olson, E. R., Clark, K. J., Aronovich, E. L., Hackett, P. B., Blazar, B. R., Tolar, J. & Scott Mcivor, R., Sep 1 2011, In : Journal of Gene Medicine. 13, 9, p. 462-469 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system

Carlson, D. F., Garbe, J. R., Tan, W., Martin, M. J., Dobrinsky, J. R., Hackett, P. B., Clark, K. J. & Fahrenkrug, S. C., Oct 1 2011, In : Transgenic Research. 20, 5, p. 1125-1137 13 p.

Research output: Contribution to journalArticle

34 Scopus citations

The Sleeping Beauty transposon system: A non-viral vector for gene therapy

Aronovich, E. L., McIvor, R. S. & Hackett, P. B., Apr 2011, In : Human molecular genetics. 20, p. R14-R20 ddr140.

Research output: Contribution to journalArticle

91 Scopus citations

Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges

Izsvák, Z., Hackett, P. B., Cooper, L. J. N. & Ivics, Z., Jun 1 2011, In : BioEssays. 33, 6, p. 478-479 2 p.

Research output: Contribution to journalComment/debate

2012

Effective Expression-Independent Gene Trapping and Mutagenesis Mediated by Sleeping Beauty Transposon

Song, G., Li, Q., Long, Y., Hackett, P. B. & Cui, Z., Sep 20 2012, In : Journal of Genetics and Genomics. 39, 9, p. 503-520 18 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effective Gene Trapping Mediated by Sleeping Beauty Transposon

Song, G., Li, Q., Long, Y., Gu, Q., Hackett, P. B. & Cui, Z., Aug 31 2012, In : PloS one. 7, 8, e44123.

Research output: Contribution to journalArticle

8 Scopus citations

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies

Kebriaei, P., Huls, H., Jena, B., Munsell, M., Jackson, R., Lee, D. A., Hackett, P. B., Rondon, G., Shpall, E., Champlin, R. E. & Cooper, L. J. N., May 1 2012, In : Human gene therapy. 23, 5, p. 444-450 7 p.

Research output: Contribution to journalArticle

82 Scopus citations

Precision Editing of Large Animal Genomes

Tan, W. S., Carlson, D. F., Walton, M. W., Fahrenkrug, S. C. & Hackett, P. B., 2012, Advances in Genetics. Academic Press Inc., p. 37-97 61 p. (Advances in Genetics; vol. 80).

Research output: Chapter in Book/Report/Conference proceedingChapter

75 Scopus citations

Targeting DNA with fingers and TALENs

Carlson, D. F., Fahrenkrug, S. C. & Hackett, P. B., Jan 1 2012, In : Molecular Therapy - Nucleic Acids. 1, 1, p. e3 e3.

Research output: Contribution to journalReview article

69 Scopus citations
2013

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

Tan, W., Carlson, D. F., Lancto, C. A., Garbe, J. R., Webster, D. A., Hackett, P. B. & Fahrenkrug, S. C., Oct 8 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 41, p. 16526-16531 6 p.

Research output: Contribution to journalArticle

193 Scopus citations

Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy

Hackett, P. B., Largaespada, D. A., Switzer, K. C. & Cooper, L. J. N., Apr 2013, In : Translational Research. 161, 4, p. 265-283 19 p.

Research output: Contribution to journalReview article

63 Scopus citations
15 Scopus citations

Sleeping beauty system to redirect T-cell specificity for human applications

Maiti, S. N., Huls, H., Singh, H., Dawson, M., Figliola, M., Olivares, S., Rao, P., Zhao, Y. J., Multani, A., Yang, G., Zhang, L., Crossland, D., Ang, S., Torikai, H., Rabinovich, B., Lee, D. A., Kebriaei, P., Hackett, P., Champlin, R. E. & Cooper, L. J. N., Feb 2013, In : Journal of Immunotherapy. 36, 2, p. 112-123 12 p.

Research output: Contribution to journalArticle

56 Scopus citations
2015

Gene therapy for neurologic manifestations of mucopolysaccharidoses

Wolf, D. A., Banerjee, S., Hackett, P. B., Whitley, C. B., McIvor, R. S. & Low, W. C., Feb 1 2015, In : Expert Opinion on Drug Delivery. 12, 2, p. 283-296 14 p.

Research output: Contribution to journalReview article

21 Scopus citations

Lysosomal storage disease: Gene therapy on both sides of the blood-brain barrier

Aronovich, E. L. & Hackett, P. B., Feb 1 2015, In : Molecular Genetics and Metabolism. 114, 2, p. 83-93 11 p.

Research output: Contribution to journalReview article

31 Scopus citations

Microwave assisted CLARITY for whole organ surveillance

Hall, B. C., Sanders, M. A., Barthel, G. M. & Hackett, P. B., Feb 1 2015, In : Molecular Genetics and Metabolism. 114, 2, p. S50

Research output: Contribution to journalArticle

Regulatory hurdles for agricult ure GMOs

Hackett, P. & Carroll, D., Mar 20 2015, In : Science. 347, 6228, 1 p.

Research output: Contribution to journalLetter

1 Scopus citations

Risks of Insertional Mutagenesis by DNA Transposons in Cancer Gene Therapy

Hackett, P. B., Starr, T. K. & Cooper, L. J. N., Jan 1 2015, Translating Gene Therapy to the Clinic: Techniques and Approaches. Elsevier Inc., p. 65-83 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
2016

Engineered swine models of cancer

Watson, A. L., Carlson, D. F., Largaespada, D. A., Hackett, P. B. & Fahrenkrug, S. C., May 9 2016, In : Frontiers in Genetics. 7, MAY, 78.

Research output: Contribution to journalReview article

Open Access
19 Scopus citations

N-Acetylgalactosamine Block-co-Polycations Form Stable Polyplexes with Plasmids and Promote Liver-Targeted Delivery

Dhande, Y. K., Wagh, B. S., Hall, B. C., Sprouse, D., Hackett, P. B. & Reineke, T. M., Mar 14 2016, In : Biomacromolecules. 17, 3, p. 830-840 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Phase i trials using sleeping beauty to generate CD19-specific CAR T cells

Kebriaei, P., Singh, H., Huls, M. H., Figliola, M. J., Bassett, R., Olivares, S., Jena, B., Dawson, M. J., Kumaresan, P. R., Su, S., Maiti, S., Dai, J., Moriarity, B., Forget, M. A., Senyukov, V., Orozco, A., Liu, T., McCarty, J., Jackson, R. N., Moyes, J. S. & 19 others, Rondon, G., Qazilbash, M., Ciurea, S., Alousi, A., Nieto, Y., Rezvani, K., Marin, D., Popat, U., Hosing, C., Shpall, E. J., Kantarjian, H., Keating, M., Wierda, W., Do, K. A., Largaespada, D. A., Lee, D. A., Hackett, P. B., Champlin, R. E. & Cooper, L. J. N., Sep 1 2016, In : Journal of Clinical Investigation. 126, 9, p. 3363-3376 14 p.

Research output: Contribution to journalArticle

Open Access
196 Scopus citations

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

Tolstyka, Z. P., Phillips, H., Cortez, M., Wu, Y., Ingle, N., Bell, J. B., Hackett, P. B. & Reineke, T. M., Jan 11 2016, In : ACS Biomaterials Science and Engineering. 2, 1, p. 43-55 13 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations
2017

Acceptance and Access to Gene Editing: Science and Our Obligations to Mankind

Fong, Y. & Hackett, P. B., Jan 4 2017, In : Molecular Therapy. 25, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Aquaculture genomics, genetics and breeding in the United States: Current status, challenges, and priorities for future research

Abdelrahman, H., ElHady, M., Alcivar-Warren, A., Allen, S., Al-Tobasei, R., Bao, L., Beck, B., Blackburn, H., Bosworth, B., Buchanan, J., Chappell, J., Daniels, W., Dong, S., Dunham, R., Durland, E., Elaswad, A., Gomez-Chiarri, M., Gosh, K., Guo, X., Hackett, P. & 31 others, Hanson, T., Hedgecock, D., Howard, T., Holland, L., Jackson, M., Jin, Y., Kahlil, K., Kocher, T., Leeds, T., Li, N., Lindsey, L., Liu, S., Liu, Z., Martin, K., Novriadi, R., Odin, R., Palti, Y., Peatman, E., Proestou, D., Qin, G., Reading, B., Rexroad, C., Roberts, S., Salem, M., Severin, A., Shi, H., Shoemaker, C., Stiles, S., Tan, S., Tang, K. F. J. & The Aquaculture Genomics, Genetics and Breeding Workshop, Hisham Abdelrahmaßn, Feb 20 2017, In : BMC Genomics. 18, 1, 191.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

Erratum to: Aquaculture genomics, genetics and breeding in the United States: Current status, challenges, and priorities for future research. [BMC Genomics. 18, (2017), (191)] DOI: 10.1186/s12864-017-3557-1

Abdelrahman, H., ElHady, M., Alcivar-Warren, A., Allen, S., Al-Tobasei, R., Bao, L., Beck, B., Blackburn, H., Bosworth, B., Buchanan, J., Chappell, J., Daniels, W., Dong, S., Dunham, R., Durland, E., Elaswad, A., Gomez-Chiarri, M., Gosh, K., Guo, X., Hackett, P. & 31 others, Hanson, T., Hedgecock, D., Howard, T., Holland, L., Jackson, M., Jin, Y., Khalil, K., Kocher, T., Leeds, T., Li, N., Lindsey, L., Liu, S., Liu, Z., Martin, K., Novriadi, R., Odin, R., Palti, Y., Peatman, E., Proestou, D., Qin, G., Reading, B., Rexroad, C., Roberts, S., Salem, M., Severin, A., Shi, H., Shoemaker, C., Stiles, S., Tan, S., Tang, K. F. J. & The Aquaculture Genomics, Genetics and Breeding Workshop, Mar 16 2017, In : BMC Genomics. 18, 1, 235.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Prolonged Expression of Secreted Enzymes in Dogs after Liver-Directed Delivery of Sleeping Beauty Transposons: Implications for Non-Viral Gene Therapy of Systemic Disease

Aronovich, E. L., Hyland, K. A., Hall, B. C., Bell, J. B., Olson, E. R., Rusten, M. U., Hunter, D. W., Matthew Ellinwood, N., Scott McIvor, R. & Hackett, P. B., Jul 2017, In : Human gene therapy. 28, 7, p. 551-564 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Transgene Expression in Dogs after Liver-Directed Hydrodynamic Delivery of Sleeping Beauty Transposons Using Balloon Catheters

Hyland, K. A., Aronovich, E. L., Olson, E. R., Bell, J. B., Rusten, M. U., Gunther, R., Hunter, D. W., Hackett, P. B. & Scott Mcivor, R., Jul 2017, In : Human gene therapy. 28, 7, p. 541-550 10 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2019

Glycopolycation-DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution

Phillips, H. R., Tolstyka, Z. P., Hall, B. C., Hexum, J. K., Hackett, P. B. & Reineke, T. M., Apr 8 2019, In : Biomacromolecules. 20, 4, p. 1530-1544 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Interspecies Organogenesis for Human Transplantation

Crane, A. T., Aravalli, R. N., Asakura, A., Grande, A. W., Krishna, V. D., Carlson, D. F., Cheeran, M. C. J., Danczyk, G., Dutton, J. R., Hackett, P. B., Hu, W. S., Li, L., Lu, W. C., Miller, Z. D., O’Brien, T. D., Panoskaltsis-Mortari, A., Parr, A. M., Pearce, C., Ruiz-Estevez, M., Shiao, M. & 6 others, Sipe, C. J., Toman, N. G., Voth, J., Xie, H., Steer, C. J. & Low, W. C., Sep 1 2019, In : Cell transplantation. 28, 9-10, p. 1091-1105 15 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations
2020

Meeting report on the 2019 international symposium of molecular design breeding in animals (Yangling, China) with the consensus on genome-editing agricultural animals and their regulation

Wang, X., Chen, Y., Sonstegard, T. S., Hackett, P. B., Fan, Z. & Li, K., Apr 1 2020, In : Transgenic Research. 29, 2, p. 263-265 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Regulatory issues for genetically modified animals

Hackett, P. B., Jan 1 2020, In : Frontiers of Agricultural Science and Engineering. 7, 2, p. 188-203 16 p., 9307.

Research output: Contribution to journalArticle

Open Access