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  • Dorothy K Hatsukami
2011

Carcinogenic tobacco-specific N-nitrosamines in US cigarettes: Three decades of remarkable neglect by the tobacco industry

Stepanov, I., Knezevich, A., Zhang, L., Watson, C. H., Hatsukami, D. K. & Hecht, S. S., May 20 2011, In : Tobacco control. 21, 1, p. 44-48 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Chronic disease management for tobacco dependence: A randomized, controlled trial

Joseph, A. M., Fu, S. S., Lindgren, B., Rothman, A. J., Kodl, M., Lando, H., Doyle, B. & Hatsukami, D., Nov 28 2011, In : Archives of Internal Medicine. 171, 21, p. 1894-1900 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

Cigarette smoking reduction and changes in nicotine dependence.

Mooney, M. E., Johnson, E. O., Breslau, N., Bierut, L. J. & Hatsukami, D. K., Jun 2011, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 13, 6, p. 426-430 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Conference on abuse liability and appeal of tobacco products: Conclusions and recommendations

Henningfield, J. E., Hatsukami, D. K., Zeller, M. & Peters, E., Jul 1 2011, In : Drug and alcohol dependence. 116, 1-3, p. 1-7 7 p.

Research output: Contribution to journalComment/debate

30 Scopus citations
28 Scopus citations
13 Scopus citations

Immediate consequences of cigarette smoking: Rapid formation of polycyclic aromatic hydrocarbon diol epoxides

Zhong, Y., Carmella, S. G., Upadhyaya, P., Hochalter, J. B., Rauch, D., Oliver, A., Jensen, J., Hatsukami, D., Wang, J., Zimmerman, C. & Hecht, S. S., Feb 18 2011, In : Chemical research in toxicology. 24, 2, p. 246-252 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Immunogenicity and smoking-cessation outcomes for a novel nicotine immunotherapeutic

Hatsukami, D. K., Jorenby, D. E., Gonzales, D., Rigotti, N. A., Glover, E. D., Oncken, C. A., Tashkin, D. P., Reus, V. I., Akhavain, R. C., Fahim, R. E. F., Kessler, P. D., Niknian, M., Kalnik, M. W. & Rennard, S. I., Mar 1 2011, In : Clinical pharmacology and therapeutics. 89, 3, p. 392-399 8 p.

Research output: Contribution to journalArticle

118 Scopus citations

Inclusion of African Americans in genetic studies: What is the barrier?

Hartz, S. M., Johnson, E. O., Saccone, N. L., Hatsukami, D., Breslau, N. & Bierut, L. J., Aug 1 2011, In : American journal of epidemiology. 174, 3, p. 336-344 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
12 Scopus citations

Metabolism of [D10]phenanthrene to tetraols in smokers for potential lung cancer susceptibility assessment: Comparison of oral and inhalation routes of administration

Zhong, Y., Wang, J., Carmella, S. G., Hochalter, J. B., Rauch, D., Oliver, A., Jensen, J., Hatsukami, D. K., Upadhyaya, P., Zimmerman, C. & Hecht, S. S., Jul 1 2011, In : Journal of Pharmacology and Experimental Therapeutics. 338, 1, p. 353-361 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Oral tobacco products: Preference and effects among smokers

Hatsukami, D. K., Jensen, J., Anderson, A., Broadbent, B., Allen, S., Zhang, Y. & Severson, H., Nov 1 2011, In : Drug and alcohol dependence. 118, 2-3, p. 230-236 7 p.

Research output: Contribution to journalArticle

24 Scopus citations
19 Scopus citations
2012

Comparing an immediate cessation versus reduction approach to smokeless tobacco cessation

Schiller, K. R., Luo, X., Anderson, A. J., Jensen, J. A., Allen, S. S. & Hatsukami, D. K., Aug 1 2012, In : Nicotine and Tobacco Research. 14, 8, p. 902-909 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people

J. Binnington, M., Zhu, A. Z. X., Renner, C. C., Lanier, A. P., Hatsukami, D. K., Benowitz, N. L. & Tyndale, R. F., Jun 1 2012, In : Pharmacogenetics and genomics. 22, 6, p. 429-440 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Dissection of the phenotypic and genotypic associations with nicotinic dependence

Chen, L. S., Baker, T. B., Grucza, R., Wang, J. C., Johnson, E. O., Breslau, N., Hatsukami, D., Smith, S. S., Saccone, N., Saccone, S., Rice, J. P., Goate, A. M. & Bierut, L. J., Apr 5 2012, In : Nicotine and Tobacco Research. 14, 4, p. 425-433 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Exposure to nicotine and carcinogens among Southwestern Alaskan native cigarette smokers and smokeless tobacco users

Benowitz, N. L., Renner, C. C., Lanier, A. P., Tyndale, R. F., Hatsukami, D. K., Lindgren, B., Stepanov, I., Watson, C. H., Sosnoff, C. S. & Jacob, P., Jun 1 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 6, p. 934-942 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T. H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guobjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K. & 132 others, Liu, Z., Lyytikäinen, L. P., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Hayward, C., Heikkilä, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H. J., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Viikari, J., Kähönen, M., Kendler, K. S., Lehtimäki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H. E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., Aug 1 2012, In : Archives of General Psychiatry. 69, 8, p. 854-861 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
12 Scopus citations

Kinetics of DNA adduct formation in the oral cavity after drinking alcohol

Balbo, S., Meng, L., Bliss, R. L., Jensen, J. A., Hatsukami, D. K. & Hecht, S. S., Apr 1 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 4, p. 601-608 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Monitoring tobacco-specific N-nitrosamines and nicotine in novel Marlboro and Camel smokeless tobacco products: Findings from round 1 of the new product watch

Stepanov, I., Biener, L., Knezevich, A., Nyman, A. L., Bliss, R., Jensen, J., Hecht, S. S. & Hatsukami, D. K., Mar 6 2012, In : Nicotine and Tobacco Research. 14, 3, p. 274-281 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Nicotine dependence and comorbid psychiatric disorders: Examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes

Chen, L. S., Xian, H., Grucza, R. A., Saccone, N. L., Wang, J. C., Johnson, E. O., Breslau, N., Hatsukami, D. & Bierut, L. J., Jun 1 2012, In : Drug and alcohol dependence. 123, SUPPL.1, p. S42-S51

Research output: Contribution to journalArticle

10 Scopus citations

Nicotine vaccines for smoking cessation

Hartmann-Boyce, J., Cahill, K., Hatsukami, D. & Cornuz, J., Aug 15 2012, In : Cochrane Database of Systematic Reviews. 2017, 12, CD007072.

Research output: Contribution to journalReview article

19 Scopus citations

Nicotine vaccines for smoking cessation.

Hartmann-Boyce, J., Cahill, K., Hatsukami, D. & Cornuz, J., 2012, In : Cochrane database of systematic reviews (Online). 8, p. CD007072

Research output: Contribution to journalReview article

29 Scopus citations

Phenanthrene metabolism in smokers: Use of a two-step diagnostic plot approach to identify subjects with extensive metabolic activation

Wang, J., Zhong, Y., Carmella, S. G., Hochalter, J. B., Rauch, D., Oliver, A., Jensen, J., Hatsukami, D. K., Upadhyaya, P., Hecht, S. S. & Zimmerman, C. L., Sep 1 2012, In : Journal of Pharmacology and Experimental Therapeutics. 342, 3, p. 750-760 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence

Haller, G., Druley, T., Vallania, F. L., Mitra, R. D., Li, P., Akk, G., Steinbach, J. H., Breslau, N., Johnson, E., Hatsukami, D., Stitzel, J., Bierut, L. J. & Goate, A. M., Feb 1 2012, In : Human molecular genetics. 21, 3, p. 647-655 9 p., ddr498.

Research output: Contribution to journalArticle

43 Scopus citations

Time course of DNA adduct formation in peripheral blood granulocytes and lymphocytes after drinking alcohol

Balbo, S., Meng, L., Bliss, R. L., Jensen, J. A., Hatsukami, D. K. & Hecht, S. S., Jul 1 2012, In : Mutagenesis. 27, 4, p. 485-490 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Tobacco and nicotine product testing

Hatsukami, D. K., Biener, L., Leischow, S. J. & Zeller, M. R., Jan 3 2012, In : Nicotine and Tobacco Research. 14, 1, p. 7-17 11 p., ntr027.

Research output: Contribution to journalReview article

25 Scopus citations
17 Scopus citations

Very Low Nicotine Content Cigarettes and Potential Consequences on Cardiovascular Disease

Joel, D. L., Denlinger, R. L., Dermody, S. S., Hatsukami, D. K., Benowitz, N. L. & Donny, E. C., Dec 1 2012, In : Current Cardiovascular Risk Reports. 6, 6, p. 534-541 8 p.

Research output: Contribution to journalReview article

2 Scopus citations
2013

Alaska native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation

Zhu, A. Z. X., Binnington, M. J., Renner, C. C., Lanier, A. P., Hatsukami, D. K., Stepanov, I., Watson, C. H., Sosnoff, C. S., Benowitz, N. L. & Tyndale, R. F., Jan 1 2013, In : Carcinogenesis. 34, 1, p. 93-101 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
26 Scopus citations

CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in alaska native tobacco users

Zhu, A. Z. X., Renner, C. C., Hatsukami, D. K., Benowitz, N. L. & Tyndale, R. F., Oct 1 2013, In : Addiction. 108, 10, p. 1818-1828 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

Stephens, S. H., Hartz, S. M., Hoft, N. R., Saccone, N. L., Corley, R. C., Hewitt, J. K., Hopfer, C. J., Breslau, N., Coon, H., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Han, Y., Hansel, N. N., Jiang, C., Korhonen, T., Lind, P. A., Liu, J. & 106 others, Lyytikäinen, L. P., Michel, M., Shaffer, J. R., Short, S. E., Sun, J., Teumer, A., Thompson, J. R., Vogelzangs, N., Vink, J. M., Wenzlaff, A., Wheeler, W., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T. H., Benjamin, D. J., Bergen, A. W., Broms, U., Cesarini, D., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D., Foroud, T., Furberg, H., Giegling, I., Gillespie, N. A., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Heikkilä, K., Hickie, I. B., Hottenga, J. J., Jousilahti, P., Kaakinen, M., Kähönen, M., Koellinger, P. D., Kittner, S., Konte, B., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., Mcneil, D. W., Medland, S. E., Montgomery, G. W., Murray, T., Nauck, M., North, K. E., Paré, P. D., Pergadia, M., Ruczinski, I., Salomaa, V., Viikari, J., Willemsen, G., Barnes, K. C., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Edenberg, H. J., Francks, C., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Johannesson, M., Kendler, K. S., Lehtimäki, T., Magnusson, P. K. E., Marazita, M. L., Marchini, J., Mitchell, B. D., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Schwartz, A. G., Shete, S., Spitz, M., Swan, G. E., Völzke, H., Veijola, J., Wei, Q., Amos, C., Cannon, D. S., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Weiss, R. B., Kraft, P., Bierut, L. J. & Ehringer, M. A., Dec 2013, In : Genetic epidemiology. 37, 8, p. 846-859 14 p.

Research output: Contribution to journalArticle

28 Scopus citations

Dose-response effects of spectrum research cigarettes

Hatsukami, D. K., Heishman, S. J., Vogel, R. I., Denlinger, R. L., Roper-Batker, A. N., Mackowick, K. M., Jensen, J., Murphy, S. E., Thomas, B. F. & Donny, E., Jun 2013, In : Nicotine and Tobacco Research. 15, 6, p. 1113-1121 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Effect of a nicotine vaccine on nicotine binding to β 2*-nicotinic acetylcholine receptors in vivo in human tobacco smokers

Esterlis, I., Hannestad, J. O., Perkins, E., Bois, F., D'Souza, D. C., Tyndale, R. F., Seibyl, J. P., Hatsukami, D. M., Cosgrove, K. P. & O'Malley, S. S., Apr 1 2013, In : American Journal of Psychiatry. 170, 4, p. 399-407 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effect of paroxetine on physiological response to stress and smoking

Kotlyar, M., Al'Absi, M., Thuras, P., Vuchetich, J. P., Adson, D. E., Nowack, A. L. & Hatsukami, D. K., Apr 2013, In : Psychosomatic medicine. 75, 3, p. 236-243 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
8 Scopus citations

Ending tobacco-caused mortality and morbidity: The case for performance standards for tobacco products

Hatsukami, D. K., Jan 1 2013, In : Tobacco control. 22, SUPPL. 1, p. i36-i37

Research output: Contribution to journalComment/debate

8 Scopus citations

Flavored and nonflavored smokeless tobacco products: Rate, pattern of use, and effects

Oliver, A. J., Jensen, J. A., Vogel, R. I., Anderson, A. J. & Hatsukami, D. K., Jan 1 2013, In : Nicotine and Tobacco Research. 15, 1, p. 88-92 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Longitudinal study of [D10]phenanthrene metabolism by the diol epoxide pathway in smokers

Hecht, S. S., Hochalter, J. B., Carmella, S. G., Zhang, Y., Rauch, D. M., Fujioka, N., Jensen, J. & Hatsukami, D. K., Mar 1 2013, In : Biomarkers. 18, 2, p. 144-150 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
8 Scopus citations
10 Scopus citations

Nicotine reduction: Strategic research plan

Hatsukami, D. K., Benowitz, N. L., Donny, E., Henningfield, J. & Zeller, M., Jun 1 2013, In : Nicotine and Tobacco Research. 15, 6, p. 1003-1013 11 p.

Research output: Contribution to journalReview article

46 Scopus citations

Nornicotine nitrosation in saliva and its relation to endogenous synthesis of n'-nitrosonornicotine in humans

Knezevich, A., Muzic, J., Hatsukami, D. K., Hecht, S. S. & Stepanov, I., Feb 1 2013, In : Nicotine and Tobacco Research. 15, 2, p. 591-595 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Reduced nicotine content cigarettes and nicotine patch

Hatsukami, D. K., Hertsgaard, L. A., Vogel, R. I., Jensen, J. A., Murphy, S. E., Hecht, S. S., Carmella, S. G., Al'Absi, M., Joseph, A. M. & Allen, S. S., Jun 1 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 6, p. 1015-1024 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Subjective responses to oral tobacco products: Scale validation

Hatsukami, D. K., Zhang, Y., O'Connor, R. J. & Severson, H. H., Jul 1 2013, In : Nicotine and Tobacco Research. 15, 7, p. 1259-1264 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in cyp2a6: The influence of genetics, race, and sex

Zhu, A. Z. X., Renner, C. C., Hatsukami, D. K., Swan, G. E., Lerman, C., Benowitz, N. L. & Tyndale, R. F., Apr 1 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 4, p. 708-718 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Tobacco use among Southwestern Alaska native people

Renner, C. C., Lanier, A. P., Lindgren, B., Jensen, J., Patten, C. A., Parascandola, M., Benowitz, N. L., Tyndale, R. F. & Hatsukami, D. K., Feb 1 2013, In : Nicotine and Tobacco Research. 15, 2, p. 401-406 6 p.

Research output: Contribution to journalArticle

14 Scopus citations