6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity

P. S. Portoghese; D. L. Larson; J. B. Jiang; A. E. Takemori; T. P. Caruso

doi:10.1021/jm00205a002

6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity

P. S. Portoghese
, D. L. Larson
, J. B. Jiang
, A. E. Takemori
, T. P. Caruso

Medicinal Chemistry

Research output: Contribution to journal › Letter › peer-review

59 Scopus citations

Original language	English (US)
Pages (from-to)	598-599
Number of pages	2
Journal	Journal of medicinal chemistry
Volume	21
Issue number	7
DOIs	https://doi.org/10.1021/jm00205a002
State	Published - 1978

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10.1021/jm00205a002

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Portoghese, P. S., Larson, D. L., Jiang, J. B., Takemori, A. E., & Caruso, T. P. (1978). 6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity. Journal of medicinal chemistry, 21(7), 598-599. https://doi.org/10.1021/jm00205a002

6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity. / Portoghese, P. S.; Larson, D. L.; Jiang, J. B. et al.
In: Journal of medicinal chemistry, Vol. 21, No. 7, 1978, p. 598-599.

Research output: Contribution to journal › Letter › peer-review

Portoghese, PS, Larson, DL, Jiang, JB, Takemori, AE & Caruso, TP 1978, '6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity', Journal of medicinal chemistry, vol. 21, no. 7, pp. 598-599. https://doi.org/10.1021/jm00205a002

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title = "6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity",

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AU - Caruso, T. P.

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6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity

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