6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity

P. S. Portoghese; D. L. Larson; J. B. Jiang; A. E. Takemori; T. P. Caruso

doi:10.1021/jm00205a002

6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity

P. S. Portoghese, D. L. Larson, J. B. Jiang, A. E. Takemori, T. P. Caruso

Medicinal Chemistry

Research output: Contribution to journal › Letter › peer-review

57 Scopus citations

Original language	English (US)
Pages (from-to)	598-599
Number of pages	2
Journal	Journal of medicinal chemistry
Volume	21
Issue number	7
DOIs	https://doi.org/10.1021/jm00205a002
State	Published - Jan 1 1978

Publisher link

10.1021/jm00205a002

Find It

Find It at U of M Libraries

Cite this

Portoghese, P. S., Larson, D. L., Jiang, J. B., Takemori, A. E., & Caruso, T. P. (1978). 6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity. Journal of medicinal chemistry, 21(7), 598-599. https://doi.org/10.1021/jm00205a002

6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity. / Portoghese, P. S.; Larson, D. L.; Jiang, J. B. et al.

In: Journal of medicinal chemistry, Vol. 21, No. 7, 01.01.1978, p. 598-599.

Research output: Contribution to journal › Letter › peer-review

Portoghese, PS, Larson, DL, Jiang, JB, Takemori, AE & Caruso, TP 1978, '6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity', Journal of medicinal chemistry, vol. 21, no. 7, pp. 598-599. https://doi.org/10.1021/jm00205a002

@article{d6fe13d92f45469eb26c6db07919e5b9,

title = "6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity",

author = "Portoghese, {P. S.} and Larson, {D. L.} and Jiang, {J. B.} and Takemori, {A. E.} and Caruso, {T. P.}",

year = "1978",

month = jan,

day = "1",

doi = "10.1021/jm00205a002",

language = "English (US)",

volume = "21",

pages = "598--599",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "7",

}

TY - JOUR

T1 - 6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity

AU - Portoghese, P. S.

AU - Larson, D. L.

AU - Jiang, J. B.

AU - Takemori, A. E.

AU - Caruso, T. P.

PY - 1978/1/1

Y1 - 1978/1/1

UR - http://www.scopus.com/inward/record.url?scp=0017903092&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017903092&partnerID=8YFLogxK

U2 - 10.1021/jm00205a002

DO - 10.1021/jm00205a002

M3 - Letter

C2 - 209185

AN - SCOPUS:0017903092

SN - 0022-2623

VL - 21

SP - 598

EP - 599

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 7

ER -

6β-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopro-pylmethyl)-4,5a-epoxy-3,14-dihydroxymorphinan (Chloranaltrexamine), a Potent Opioid Receptor Alkylating Agent with Ultralong Narcotic Antagonist Activity

Publisher link

Find It

Other files and links

Cite this