4-Deacetyltaxol and 10-Acetyl-4-deacetyltaxotere: Synthesis and Biological Evaluation

Apurba Datta, Lalith R. Jayasinghe, Gunda I. Georg

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

4-Deacetyltaxol and 10-acetyl-4-deacetyltaxotere were synthesized for the first time from 7-(triethylsilyl)-4-deacetylbaccatin III. These analogs were found to be inactive in the microtubule assembly assay.

Original languageEnglish (US)
Pages (from-to)4258-4260
Number of pages3
JournalJournal of Medicinal Chemistry
Volume37
Issue number24
DOIs
StatePublished - Nov 1 1994

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