3-Dimensional brain source imaging by means of laplacian weighted minimum norm estimate in a realistic geometry head model

Lei Ding, Bin He

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

We investigated the source localization performance of the Laplacian weighted minimum norm (LWMN) estimate technique in a realistic geometry (RG) head model in the present study. We simulated current sources at different brain regions with various noise levels. The present results show there is no obvious depth dependency on the three-dimensional (3D) source estimation. The average source localization error over all simulated cases is about 10 mm. The tangential sources exhibit larger localization errors than the radial sources when they are close to the epicortical surface. The localization error will increase when the noise level increases. The LWMN technique was applied to source imaging of motor potentials induced by finger movement in a human subject. Both activities in the motor and premotor cortex, which are related to the execution and coordinating of the finger movement, were reconstructed by the LWMN technique. The present study suggests that LWMN has great ability in 3D sources imaging.

Original languageEnglish (US)
Title of host publicationProceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Pages1430-1433
Number of pages4
StatePublished - Dec 1 2005
Event2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai, China
Duration: Sep 1 2005Sep 4 2005

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume7 VOLS
ISSN (Print)0589-1019

Other

Other2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
CountryChina
CityShanghai
Period9/1/059/4/05

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Keywords

  • Distributed source model
  • EEG
  • LORETA
  • Realistic geometry
  • Source localization LWMN

Cite this

Ding, L., & He, B. (2005). 3-Dimensional brain source imaging by means of laplacian weighted minimum norm estimate in a realistic geometry head model. In Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 (pp. 1430-1433). [1616699] (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 7 VOLS).