2024 Guideline for the Primary Prevention of Stroke: A Guideline from the American Heart Association/American Stroke Association

Cheryl Bushnell; Walter N. Kernan; Anjail Z. Sharrief; Seemant Chaturvedi; John W. Cole; William K. Cornwell; Christine Cosby-Gaither; Sarah Doyle; Larry B. Goldstein; Olive Lennon; Deborah A. Levine; Mary Love; Eliza Miller; Mai Nguyen-Huynh; Jennifer Rasmussen-Winkler; Kathryn M. Rexrode; Nicole Rosendale; Satyam Sarma; Daichi Shimbo; Alexis N. Simpkins; Erica S. Spatz; Lisa R. Sun; Vin Tangpricha; Dawn Turnage; Gabriela Velazquez; Paul K. Whelton; Tatjana Rundek; Karen Furie; Niloufar Hadidi; Hugo Aparicio; Trissa Babrowski; Stacy Beck; Jordana Cohen; Keith Diaz; Nada El Husseini; Bethany Gibbs; Rebecca Gottesman; Michael Irwig; Dinesh Jillella; Ronda Johnson; Erica Jones; Lori Jordon; Suzanne Judd; Salomeh Keyhani; Lisa Leffert; Donald Lloyd-Jones; Jo Ann Manson; Jorge Moreno; Setareh Salehi Omran; Mayowa Owolabi; Matthew Robbins; Marc Schermerhorn; Souvik Sen; Michael Shapiro; Lesli Skolarus; Damon Swift; Anthony Viera; Chloe Villavaso; Bradford Worrall; Jose Romano; Nerissa Ko; Joseph P. Broderick; Sepideh Amin-Hanjani; Mona Bahouth; Michelle Camicia; Mandip Dhamoon; Justin Frazer; Jose Gutierrez; Koto Ishida; Ronald Lazar; William Mack; Soojin Park; Lauren Sansing; Laura Stein; Kori Zachrison; Keith Churchwell; Nancy Brown; Mariell Jessup; Nicole Aiello Sapio; Radhika Rajgopal Singh; Prashant Nedungadi; Sabrina Times; Melanie Stephens-Lyman; Anne Leonard

doi:10.1161/str.0000000000000475

2024 Guideline for the Primary Prevention of Stroke: A Guideline from the American Heart Association/American Stroke Association

Cheryl Bushnell
, Walter N. Kernan
, Anjail Z. Sharrief
, Seemant Chaturvedi
, John W. Cole
, William K. Cornwell
, Christine Cosby-Gaither
, Sarah Doyle
, Larry B. Goldstein
, Olive Lennon
, Deborah A. Levine
, Mary Love
, Eliza Miller
, Mai Nguyen-Huynh
, Jennifer Rasmussen-Winkler
, Kathryn M. Rexrode
, Nicole Rosendale
, Satyam Sarma
, Daichi Shimbo
, Alexis N. Simpkins

Erica S. Spatz, Lisa R. Sun, Vin Tangpricha, Dawn Turnage, Gabriela Velazquez, Paul K. Whelton, Tatjana Rundek, Karen Furie, Niloufar Hadidi, Hugo Aparicio, Trissa Babrowski, Stacy Beck, Jordana Cohen, Keith Diaz, Nada El Husseini, Bethany Gibbs, Rebecca Gottesman, Michael Irwig, Dinesh Jillella, Ronda Johnson, Erica Jones, Lori Jordon, Suzanne Judd, Salomeh Keyhani, Lisa Leffert, Donald Lloyd-Jones, Jo Ann Manson, Jorge Moreno, Setareh Salehi Omran, Mayowa Owolabi, Matthew Robbins, Marc Schermerhorn, Souvik Sen, Michael Shapiro, Lesli Skolarus, Damon Swift, Anthony Viera, Chloe Villavaso, Bradford Worrall, Jose Romano, Nerissa Ko, Joseph P. Broderick, Sepideh Amin-Hanjani, Mona Bahouth, Michelle Camicia, Mandip Dhamoon, Justin Frazer, Jose Gutierrez, Koto Ishida, Ronald Lazar, William Mack, Soojin Park, Lauren Sansing, Laura Stein, Kori Zachrison, Keith Churchwell, Nancy Brown, Mariell Jessup, Nicole Aiello Sapio, Radhika Rajgopal Singh, Prashant Nedungadi, Sabrina Times, Melanie Stephens-Lyman, Anne Leonard

Academics (Nursing)

Research output: Contribution to journal › Review article › peer-review

283 Scopus citations

Abstract

AIM: The "2024 Guideline for the Primary Prevention of Stroke"replaces the 2014 "Guidelines for the Primary Prevention of Stroke."This updated guideline is intended to be a resource for clinicians to use to guide various prevention strategies for individuals with no history of stroke. METHODS: A comprehensive search for literature published since the 2014 guideline; derived from research involving human participants published in English; and indexed in MEDLINE, PubMed, Cochrane Library, and other selected and relevant databases was conducted between May and November 2023. Other documents on related subject matter previously published by the American Heart Association were also reviewed. STRUCTURE: Ischemic and hemorrhagic strokes lead to significant disability but, most important, are preventable. The 2024 primary prevention of stroke guideline provides recommendations based on current evidence for strategies to prevent stroke throughout the life span. These recommendations align with the American Heart Association's Life's Essential 8 for optimizing cardiovascular and brain health, in addition to preventing incident stroke. We also have added sex-specific recommendations for screening and prevention of stroke, which are new compared with the 2014 guideline. Many recommendations for similar risk factor prevention were updated, new topics were reviewed, and recommendations were created when supported by sufficient-quality published data.

Original language	English (US)
Pages (from-to)	e344-e424
Journal	Stroke
Volume	55
Issue number	12
DOIs	https://doi.org/10.1161/str.0000000000000475
State	Published - Dec 1 2024

Bibliographical note

Publisher Copyright:
© 2024 American Heart Association, Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

AHA Scientific Statements
guideline
hemorrhagic stroke
ischemic stroke
stroke

Publisher link

10.1161/str.0000000000000475

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Bushnell, C., Kernan, W. N., Sharrief, A. Z., Chaturvedi, S., Cole, J. W., Cornwell, W. K., Cosby-Gaither, C., Doyle, S., Goldstein, L. B., Lennon, O., Levine, D. A., Love, M., Miller, E., Nguyen-Huynh, M., Rasmussen-Winkler, J., Rexrode, K. M., Rosendale, N., Sarma, S., Shimbo, D., ... Leonard, A. (2024). 2024 Guideline for the Primary Prevention of Stroke: A Guideline from the American Heart Association/American Stroke Association. Stroke, 55(12), e344-e424. https://doi.org/10.1161/str.0000000000000475

Bushnell, C, Kernan, WN, Sharrief, AZ, Chaturvedi, S, Cole, JW, Cornwell, WK, Cosby-Gaither, C, Doyle, S, Goldstein, LB, Lennon, O, Levine, DA, Love, M, Miller, E, Nguyen-Huynh, M, Rasmussen-Winkler, J, Rexrode, KM, Rosendale, N, Sarma, S, Shimbo, D, Simpkins, AN, Spatz, ES, Sun, LR, Tangpricha, V, Turnage, D, Velazquez, G, Whelton, PK, Rundek, T, Furie, K, Hadidi, N, Aparicio, H, Babrowski, T, Beck, S, Cohen, J, Diaz, K, El Husseini, N, Gibbs, B, Gottesman, R, Irwig, M, Jillella, D, Johnson, R, Jones, E, Jordon, L, Judd, S, Keyhani, S, Leffert, L, Lloyd-Jones, D, Manson, JA, Moreno, J, Omran, SS, Owolabi, M, Robbins, M, Schermerhorn, M, Sen, S, Shapiro, M, Skolarus, L, Swift, D, Viera, A, Villavaso, C, Worrall, B, Romano, J, Ko, N, Broderick, JP, Amin-Hanjani, S, Bahouth, M, Camicia, M, Dhamoon, M, Frazer, J, Gutierrez, J, Ishida, K, Lazar, R, Mack, W, Park, S, Sansing, L, Stein, L, Zachrison, K, Churchwell, K, Brown, N, Jessup, M, Sapio, NA, Singh, RR, Nedungadi, P, Times, S, Stephens-Lyman, M & Leonard, A 2024, '2024 Guideline for the Primary Prevention of Stroke: A Guideline from the American Heart Association/American Stroke Association', Stroke, vol. 55, no. 12, pp. e344-e424. https://doi.org/10.1161/str.0000000000000475

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abstract = "AIM: The {"}2024 Guideline for the Primary Prevention of Stroke{"}replaces the 2014 {"}Guidelines for the Primary Prevention of Stroke.{"}This updated guideline is intended to be a resource for clinicians to use to guide various prevention strategies for individuals with no history of stroke. METHODS: A comprehensive search for literature published since the 2014 guideline; derived from research involving human participants published in English; and indexed in MEDLINE, PubMed, Cochrane Library, and other selected and relevant databases was conducted between May and November 2023. Other documents on related subject matter previously published by the American Heart Association were also reviewed. STRUCTURE: Ischemic and hemorrhagic strokes lead to significant disability but, most important, are preventable. The 2024 primary prevention of stroke guideline provides recommendations based on current evidence for strategies to prevent stroke throughout the life span. These recommendations align with the American Heart Association's Life's Essential 8 for optimizing cardiovascular and brain health, in addition to preventing incident stroke. We also have added sex-specific recommendations for screening and prevention of stroke, which are new compared with the 2014 guideline. Many recommendations for similar risk factor prevention were updated, new topics were reviewed, and recommendations were created when supported by sufficient-quality published data.",

keywords = "AHA Scientific Statements, guideline, hemorrhagic stroke, ischemic stroke, stroke",

author = "Cheryl Bushnell and Kernan, \{Walter N.\} and Sharrief, \{Anjail Z.\} and Seemant Chaturvedi and Cole, \{John W.\} and Cornwell, \{William K.\} and Christine Cosby-Gaither and Sarah Doyle and Goldstein, \{Larry B.\} and Olive Lennon and Levine, \{Deborah A.\} and Mary Love and Eliza Miller and Mai Nguyen-Huynh and Jennifer Rasmussen-Winkler and Rexrode, \{Kathryn M.\} and Nicole Rosendale and Satyam Sarma and Daichi Shimbo and Simpkins, \{Alexis N.\} and Spatz, \{Erica S.\} and Sun, \{Lisa R.\} and Vin Tangpricha and Dawn Turnage and Gabriela Velazquez and Whelton, \{Paul K.\} and Tatjana Rundek and Karen Furie and Niloufar Hadidi and Hugo Aparicio and Trissa Babrowski and Stacy Beck and Jordana Cohen and Keith Diaz and \{El Husseini\}, Nada and Bethany Gibbs and Rebecca Gottesman and Michael Irwig and Dinesh Jillella and Ronda Johnson and Erica Jones and Lori Jordon and Suzanne Judd and Salomeh Keyhani and Lisa Leffert and Donald Lloyd-Jones and Manson, \{Jo Ann\} and Jorge Moreno and Omran, \{Setareh Salehi\} and Mayowa Owolabi and Matthew Robbins and Marc Schermerhorn and Souvik Sen and Michael Shapiro and Lesli Skolarus and Damon Swift and Anthony Viera and Chloe Villavaso and Bradford Worrall and Jose Romano and Nerissa Ko and Broderick, \{Joseph P.\} and Sepideh Amin-Hanjani and Mona Bahouth and Michelle Camicia and Mandip Dhamoon and Justin Frazer and Jose Gutierrez and Koto Ishida and Ronald Lazar and William Mack and Soojin Park and Lauren Sansing and Laura Stein and Kori Zachrison and Keith Churchwell and Nancy Brown and Mariell Jessup and Sapio, \{Nicole Aiello\} and Singh, \{Radhika Rajgopal\} and Prashant Nedungadi and Sabrina Times and Melanie Stephens-Lyman and Anne Leonard",

note = "Publisher Copyright: {\textcopyright} 2024 American Heart Association, Inc.",

year = "2024",

month = dec,

day = "1",

doi = "10.1161/str.0000000000000475",

language = "English (US)",

volume = "55",

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T1 - 2024 Guideline for the Primary Prevention of Stroke

T2 - A Guideline from the American Heart Association/American Stroke Association

AU - Bushnell, Cheryl

AU - Kernan, Walter N.

AU - Sharrief, Anjail Z.

AU - Chaturvedi, Seemant

AU - Cole, John W.

AU - Cornwell, William K.

AU - Cosby-Gaither, Christine

AU - Doyle, Sarah

AU - Goldstein, Larry B.

AU - Lennon, Olive

AU - Levine, Deborah A.

AU - Love, Mary

AU - Miller, Eliza

AU - Nguyen-Huynh, Mai

AU - Rasmussen-Winkler, Jennifer

AU - Rexrode, Kathryn M.

AU - Rosendale, Nicole

AU - Sarma, Satyam

AU - Shimbo, Daichi

AU - Simpkins, Alexis N.

AU - Spatz, Erica S.

AU - Sun, Lisa R.

AU - Tangpricha, Vin

AU - Turnage, Dawn

AU - Velazquez, Gabriela

AU - Whelton, Paul K.

AU - Rundek, Tatjana

AU - Furie, Karen

AU - Hadidi, Niloufar

AU - Aparicio, Hugo

AU - Babrowski, Trissa

AU - Beck, Stacy

AU - Cohen, Jordana

AU - Diaz, Keith

AU - El Husseini, Nada

AU - Gibbs, Bethany

AU - Gottesman, Rebecca

AU - Irwig, Michael

AU - Jillella, Dinesh

AU - Johnson, Ronda

AU - Jones, Erica

AU - Jordon, Lori

AU - Judd, Suzanne

AU - Keyhani, Salomeh

AU - Leffert, Lisa

AU - Lloyd-Jones, Donald

AU - Manson, Jo Ann

AU - Moreno, Jorge

AU - Omran, Setareh Salehi

AU - Owolabi, Mayowa

AU - Robbins, Matthew

AU - Schermerhorn, Marc

AU - Sen, Souvik

AU - Shapiro, Michael

AU - Skolarus, Lesli

AU - Swift, Damon

AU - Viera, Anthony

AU - Villavaso, Chloe

AU - Worrall, Bradford

AU - Romano, Jose

AU - Ko, Nerissa

AU - Broderick, Joseph P.

AU - Amin-Hanjani, Sepideh

AU - Bahouth, Mona

AU - Camicia, Michelle

AU - Dhamoon, Mandip

AU - Frazer, Justin

AU - Gutierrez, Jose

AU - Ishida, Koto

AU - Lazar, Ronald

AU - Mack, William

AU - Park, Soojin

AU - Sansing, Lauren

AU - Stein, Laura

AU - Zachrison, Kori

AU - Churchwell, Keith

AU - Brown, Nancy

AU - Jessup, Mariell

AU - Sapio, Nicole Aiello

AU - Singh, Radhika Rajgopal

AU - Nedungadi, Prashant

AU - Times, Sabrina

AU - Stephens-Lyman, Melanie

AU - Leonard, Anne

PY - 2024/12/1

Y1 - 2024/12/1

N2 - AIM: The "2024 Guideline for the Primary Prevention of Stroke"replaces the 2014 "Guidelines for the Primary Prevention of Stroke."This updated guideline is intended to be a resource for clinicians to use to guide various prevention strategies for individuals with no history of stroke. METHODS: A comprehensive search for literature published since the 2014 guideline; derived from research involving human participants published in English; and indexed in MEDLINE, PubMed, Cochrane Library, and other selected and relevant databases was conducted between May and November 2023. Other documents on related subject matter previously published by the American Heart Association were also reviewed. STRUCTURE: Ischemic and hemorrhagic strokes lead to significant disability but, most important, are preventable. The 2024 primary prevention of stroke guideline provides recommendations based on current evidence for strategies to prevent stroke throughout the life span. These recommendations align with the American Heart Association's Life's Essential 8 for optimizing cardiovascular and brain health, in addition to preventing incident stroke. We also have added sex-specific recommendations for screening and prevention of stroke, which are new compared with the 2014 guideline. Many recommendations for similar risk factor prevention were updated, new topics were reviewed, and recommendations were created when supported by sufficient-quality published data.

AB - AIM: The "2024 Guideline for the Primary Prevention of Stroke"replaces the 2014 "Guidelines for the Primary Prevention of Stroke."This updated guideline is intended to be a resource for clinicians to use to guide various prevention strategies for individuals with no history of stroke. METHODS: A comprehensive search for literature published since the 2014 guideline; derived from research involving human participants published in English; and indexed in MEDLINE, PubMed, Cochrane Library, and other selected and relevant databases was conducted between May and November 2023. Other documents on related subject matter previously published by the American Heart Association were also reviewed. STRUCTURE: Ischemic and hemorrhagic strokes lead to significant disability but, most important, are preventable. The 2024 primary prevention of stroke guideline provides recommendations based on current evidence for strategies to prevent stroke throughout the life span. These recommendations align with the American Heart Association's Life's Essential 8 for optimizing cardiovascular and brain health, in addition to preventing incident stroke. We also have added sex-specific recommendations for screening and prevention of stroke, which are new compared with the 2014 guideline. Many recommendations for similar risk factor prevention were updated, new topics were reviewed, and recommendations were created when supported by sufficient-quality published data.

KW - AHA Scientific Statements

KW - guideline

KW - hemorrhagic stroke

KW - ischemic stroke

KW - stroke

UR - https://www.scopus.com/pages/publications/85210096518

UR - https://www.scopus.com/pages/publications/85210096518#tab=citedBy

U2 - 10.1161/str.0000000000000475

DO - 10.1161/str.0000000000000475

M3 - Review article

C2 - 39429201

AN - SCOPUS:85210096518

SN - 0039-2499

VL - 55

SP - e344-e424

JO - Stroke

JF - Stroke

IS - 12

ER -

2024 Guideline for the Primary Prevention of Stroke: A Guideline from the American Heart Association/American Stroke Association

Abstract

Bibliographical note

UN SDGs

Keywords

Publisher link

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