2011 ACCF/AHA focused update of the guideline for the management of patients with peripheral artery disease (Updating the 2005 Guideline): A report of the american college of cardiology foundation/American Heart Association task force on practice guidelines

Thom W. Rooke, Alan T. Hirsch, Sanjay Misra, Anton N. Sidawy, Joshua A. Beckman, Laura K. Findeiss, Jafar Golzarian, Heather L. Gornik, Jonathan L. Halperin, Michael R. Jaff, Gregory L. Moneta, Jeffrey W. Olin, James C. Stanley, Christopher J. White, John V. White, R. Eugene Zierler, for Cardiovascular Angiography Society for Cardiovascular Angiography, of Interventional Radiology Society of Interventional Radiology, for Vascular Medicine Society for Vascular Medicine, for Vascular Surgery Society for Vascular Surgery

Research output: Contribution to journalArticlepeer-review

826 Scopus citations
Original languageEnglish (US)
Pages (from-to)2020-2045
Number of pages26
Issue number18
StatePublished - Nov 1 2011

Bibliographical note

Funding Information:
The writing group has reviewed the results of the multicenter BASIL (Bypass Versus Angioplasty in Severe Ischaemia of the Leg) trial funded by the United Kingdom National Institute of Health Research and Health Technology Assessment Programme ( 54 ). During a 5-year period, 452 patients with severe limb ischemia (characterized by rest/night pain and tissue loss, such as skin ulceration and gangrene, and thus including patients defined by this PAD guideline syndrome term critical limb ischemia) were randomly assigned to an initial treatment strategy of either open surgery or balloon angioplasty. Major clinical outcomes evaluated in this trial were amputation-free survival and overall survival. The initial results published in 2005 indicated that in patients with severe limb ischemia due to infrainguinal disease, the short-term clinical outcomes between bypass surgery–first and balloon angioplasty–first were similar ( 54,55 ). These initial results showed that bypass surgery–first was one third more expensive and was associated with higher morbidity than balloon angioplasty–first.

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