A key enabler of lifestyle technologies that are expected to be pervasive in the next decade will be due to the increased performance of integrated circuits. This next generation of circuits will have to overcome a significantly different set of issues from conventional technologies, and this tutorial provides the attendee with an appreciation for and an introduction to techniques used to solve these problems. The analysis and design of future generations of integrated circuits operating at frequencies in excess of 10 GHz faces major challenges that will severely impact commonly used circuit design techniques and CAD tools. A conventional definition of high-performance that places paramount importance on high speed is no longer viable, and the paradigm will change significantly in the future as other factors must be considered. Next-generation design techniques will also be impacted by trends in technology scaling that seriously impact circuit styles and CAD tools, such as lower resistivity interconnect (such as copper), low K dielectrics, faster devices (such as SOI and SiGe technologies), improved cooling techniques, and wider busses. This tutorial addresses design and CAD techniques to be used in nanometer technologies, where feature sizes will be below 100nm. Today's high-end designs are already entering this regime, with designs entering the 90nm technology node at target frequencies of 5 GHz. In such an environment, high-performance design will imply the simultaneous optimization of delay, power dissipation, signal integrity, and circuit reliability. Moreover, design will have to be carried out in an environment where process variations will see larger changes within-die and across-die than in current technologies.