1,2-Disubstituted Alkenes as Migratory Insertion Participants in Zn(II)-Promoted Metalloamination/Cyclization of N,N-Dimethylhydrazinoalkenes

Bryce Sunsdahl, Ky Mickelsen, Sean Zabawa, Bryon K. Anderson, Tom Livinghouse

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Diethylzinc-mediated metalloamination/cyclization of unsaturated N,N-dimethylhydrazines has been extended to the use of 1,2-disubstituted alkenes as N-Zn migratory insertion acceptors. Representative 2-arylethenes and vinylcyclopropanes readily serve as reaction participants in metalloamination/cyclization-allylation cascades.

Original languageEnglish (US)
Pages (from-to)10160-10164
Number of pages5
JournalJournal of Organic Chemistry
Volume81
Issue number21
DOIs
StatePublished - Nov 4 2016

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