1-Cyano-3-(1H)-1,2-benziodoxols: stable cyanoiodinanes and efficient reagents for direct N-alkyl cyanation of N,N-dialkylarylamines

Viktor Zhdankin, Chris J. Kuehl, Alexei P. Krasutsky, Jason T. Bolz, Brian Mismash, Jessica K. Woodward, Angela J. Simonsen

Research output: Contribution to journalArticle

96 Scopus citations

Abstract

Cyanobenziodoxols 2 and 4 can be prepared from benziodoxols 1 or 3 and cyanotrimethylsilane in the form of stable, crystalline compounds. Cyanobenziodoxol 2 reacts with N,N-dimethylary lamines under mild conditions to afford N-(cyanomethyl)-N-methylarylamines 6 in excellent yields.

Original languageEnglish (US)
Pages (from-to)7975-7978
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number44
DOIs
StatePublished - Oct 30 1995

Fingerprint Dive into the research topics of '1-Cyano-3-(1H)-1,2-benziodoxols: stable cyanoiodinanes and efficient reagents for direct N-alkyl cyanation of N,N-dialkylarylamines'. Together they form a unique fingerprint.

  • Cite this