1-Amido-3-(1H)-1,2-benziodoxoles: Stable amidoiodanes and reagents for direct amidation of organic substrates

Viktor Zhdankin, Marc McSherry, Brian Mismash, Jason T. Bolz, Jessica K. Woodward, Ruslan M. Arbit, Scott Erickson

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Amidobenziodoxoles 2 can be prepared from benziodoxole 1, trimethylsilyltriflate and the appropriate amides in the form of stable, microcrystalline compounds. Amidobenziodoxoles 2 react with adamantane 3 or N,N-dimethylarylamines 5 to afford the corresponding products of amidation, 4 and 6.

Original languageEnglish (US)
Pages (from-to)21-24
Number of pages4
JournalTetrahedron Letters
Issue number1
StatePublished - Jan 6 1997

Bibliographical note

Funding Information:
In conclusion, we have prepared and isolated as individual, stable compounds amidobenziodoxoles 2a- e. Compounds 2 are potentially useful reagents for direct amidation of adamantane and N,N- dialkylarylamines. Acknowledgement. This work was supported by a research grant from the National Science Foundation (NSF/CHE-9505868) and by the Undergraduate Research Opportunities Program at the University of Minnesota.


Dive into the research topics of '1-Amido-3-(1H)-1,2-benziodoxoles: Stable amidoiodanes and reagents for direct amidation of organic substrates'. Together they form a unique fingerprint.

Cite this