Mutation of Breast Cancer Cell Genomic DNA by APOBEC3B

  • Burns, Michael B (PI)

Project: Research project

Project Details

Description

The APOBEC family of proteins has a variety of roles in immunity by promoting antibody diversity and restricting retroviruses and retroelement transposition. As cytosine deaminases, they generate C/G to T/A transition mutations. I hypothesize that the AP
StatusFinished
Effective start/end date9/1/119/30/14

Funding

  • U.S. DEPARTMENT OF DEFENSE

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