Project Details
Layman's description
Long-term use of opioids to treat pain can create a need for the person to take increasing doses of medication to get the same pain relief. We suspect that giving long-acting buprenorphine (an opioid) to animals creates the same problem instead of providing long-acting pain relief.
Key findings
Mice and rats develop acute tolerance to the analgesic effects of sustained-release buprenorphine. Currently evaluating other species.
| Short title | SRB and acute opioid tolerance |
|---|---|
| Acronym | SRB |
| Status | Active |
| Effective start/end date | 7/15/16 → … |
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