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• A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease Therapy

  Sudel, B.

  TARGET PHARMASOLUTIONS, INC

  1/23/19 → 1/31/24

  Project: Research project

  • Inflammatory Bowel Diseases
  • Longitudinal Studies
  • Observational Studies
  • Therapeutics

• Role of nucleosome dynamics in epigenetic inheritance

  Yu, C.

  NIH NIGMS NATL INST OF GENERAL

  2/1/20 → 1/31/24

  Project: Research project

  • Nucleosomes
  • Epigenomics

• Technology to Realize the Full Potential of UHF MRI

  Ugurbil, K., Adriany, G., Akcakaya, M., Auerbach, E. J., Bolan, P. J., Chen, W., Eryaman, Y., Garwood, M., Ghose, G., Hayden, B. Y., Mangia, S., Marjanska, M., Metzger, G., Michaeli, S., Moeller, S., Van de Moortele, P. & Wu, X.

  NIH NATL INST OF BIOMEDICAL IM

  2/1/19 → 1/31/24

  Project: Research project

• Immune cells as a driver of cell non-autonomous aging

  Niedernhofer, L. J., Arriaga, E., Robbins, P. D. & Stromnes, I. M.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  4/1/19 → 1/31/24

  Project: Research project

  • Aging of materials

• The effect of inflammation and damage to lymph node structures on durable protective immunity following vaccination

  Schacker, T. W., Beilman, G. J., Chipman, J. G., Helgeson, E. S., Jenkins, M., Khoruts, A. & Reilly, C. S.

  NIH Nat'l Inst of Allergy & Infect Dis

  2/25/19 → 1/31/24

  Project: Research project

  • vaccination
  • immunity
  • damage
  • effect

• Targeting Cellular Senescence to Extend Healthspan

  Robbins, P. D. & Niedernhofer, L. J.

  Mayo Clinic

  6/1/19 → 1/31/24

  Project: Research project

• Genetic Factors of Birth Defects-Genomics Testing

  Tsai, M. Y. & Pankratz, N. D.

  National Institutes of Health

  5/10/17 → 2/9/24

  Project: Research project

  • Genomics

• A Comparison of Tube and Gel Technology for anti-D titer testing

  Cohn, C. S.

  ORTHO-CLINICAL DIAGNOSTICS, INC.

  2/17/20 → 2/16/24

  Project: Research project

  • gels
  • tubes

• A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to EvaluateEfficacy and Safety of Lenabasum in Dermatomyositis

  Molitor, J. A.

  CORBUS PHARMACEUTICALS, INC.

  2/26/19 → 2/28/24

  Project: Research project

  • Placebos
  • Safety

• Prospective, International, Multi-Center, Randomized Clinical Investigation Of TransMedics Organ Care System (OCS Lung) For Lung Preservation And Transplantation

  Huddleston, S. J.

  TRANSMEDICS, INC.

  3/1/19 → 2/28/24

  Project: Research project

  • Transplantation
  • Lung

• A Phase II Single-Arm Study of Therapeutic Iobenguane (131I) For Relapsed, High-Risk Neuroblastoma Subjects (OPTIMUM Trial)PROTOCOL MIBG 2014-01

  Greengard, E. G.

  JUBILANT DRAXLMAGE INC

  2/1/19 → 2/28/24

  Project: Research project

  • 3-Iodobenzylguanidine
  • Neuroblastoma
  • Therapeutics

• A MULTICENTER, LONGITUDINAL, PROSPECTIVE, PHARMACOKINETIC,PHASE 1B STUDY IN WOMEN WITH CHRONIC INFLAMMATORY DISEASES TREATED WITHCIMZIA® (CERTOLIZUMAB PEGOL) DURING PREGNANCY

  Shmidt, E.

  UCB Pharma S.A.

  2/26/20 → 2/28/24

  Project: Research project

  • Certolizumab Pegol
  • Pharmacokinetics
  • Chronic Disease
  • Pregnancy

• Momentum 3 Pivotal Cohort Extended Follow-up Post-Approval Study

  John, R.

  Abbott Laboratories

  3/1/19 → 2/28/24

  Project: Research project

• OCS Lung EXPAND Post-Approval Study - EXPAND Follow-Up Data Collection

  Huddleston, S. J.

  TRANSMEDICS, INC.

  3/8/19 → 2/28/24

  Project: Research project

  • Lung

• Can tDCS accelerate and sustain the cognitive benefits of targeted cognitive training in schizophrenia

  Ramsay, I. S.

  NIH Nat'l Institute of Mental Health

  3/5/19 → 2/28/24

  Project: Research project

  • Schizophrenia

• Educational and Early Life Predictors of Mild Cognitive Impairment: New Evidence about Mediators and Moderators from High School & Beyond

  Warren (he/him/his), R. & Maclehose, R. F.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  5/15/19 → 2/29/24

  Project: Research project

  • Cognitive Dysfunction

• Perennial crops to improve soil health and sustain yields for climate extremes

  Gutknecht, J. L., Fernandez, C. W., Hunter, M. C., Jungers, J. M. & Sheaffer, C. C.

  USDA Nat'l Inst. of Food & Agriculture

  3/1/19 → 2/29/24

  Project: Research project

  • soil quality
  • climate
  • crops

• Deep sequencing, phenotyping, and imputation in large-scale biobanks: A novel and cost-effective framework to identify rare mutations associated with addiction

  Vrieze, S. I., Albert, F. W. & Lee, A. M.

  NIH NIDA NATL INST ON DRUG AB

  5/1/19 → 2/29/24

  Project: Research project

  • High-Throughput Nucleotide Sequencing
  • Costs and Cost Analysis
  • Mutation

• A Phase III Randomized Placebo-Controlled Study to Examine the Efficacy and Safety of DAS181 for theTreatment of Lower Respiratory Tract Parainfluenza Infection in Immunocompromised Subjects

  Young, J. H.

  ANSUN BIOPHARMA, INC.

  2/6/19 → 2/29/24

  Project: Research project

  • DAS181
  • Paramyxoviridae Infections
  • Respiratory Tract Infections
  • Placebos
  • Safety

• Detection and Activation of CD4+ T cells with Low Affinity TCRs

  Jenkins, M.

  NIH Nat'l Inst of Allergy & Infect Dis

  3/1/19 → 2/29/24

  Project: Research project

  • T-Lymphocytes

• CAREER: Scaling-up effects of biodiversity on ecosystem productivity: from local communities to landscapes

  Isbell, F.

  National Science Foundation

  3/1/19 → 2/29/24

  Project: Research project

  • biodiversity
  • productivity
  • ecosystem
  • effect

• FT516-102:APhase I, Open-Label, Multicenter Study of FT516 in Combination with Monoclonal Antibodies in Subjectswith Advanced Solid Tumors

  Patel, M. R.

  Fate Therapeutics, Inc.

  2/20/20 → 2/29/24

  Project: Research project

  • Multicenter Studies
  • Monoclonal Antibodies
  • Neoplasms

• Development and Validation of a Gene Expression Assay to Predict the Risk of Recurrence Disease in Cutaneous Squamous Cell Carcinoma

  Maher, I.

  CASTLE BIOSCIENCES, INC.

  2/6/19 → 2/29/24

  Project: Research project

  • Squamous Cell Carcinoma
  • Gene Expression
  • Recurrence
  • Skin

• Neurobiology of Female Sexual Desire

  Meisel, R. L.

  NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

  3/15/19 → 2/29/24

  Project: Research project

  • neurosciences

• Mechanisms of mTORC1 signaling to protein degradation pathways

  Kim, D.

  NIH NIGMS NATL INST OF GENERAL

  3/8/19 → 2/29/24

  Project: Research project

  • Mechanistic Target of Rapamycin Complex 1
  • Proteolysis

• Phase II Study of Pembrolizumab in the Immunoreactive Ovarian Cancer Subtype

  Winterhoff, B. J.

  UNIVERSITY OF CALIFORNIA, LOS ANGEL

  3/6/19 → 3/30/24

  Project: Research project

  • pembrolizumab

• Bayer 20414: A multicenter, non-randomized, open-label, multiple dose escalation study to evaluate thesafety and tolerability of subcutaneous BAY 1093884 in males with hemophilia

  Mazepa, M.

  BAYER HEALTHCARE PHARMACEUTICALS

  3/11/19 → 3/30/24

  Project: Research project

  • Hemophilia A
  • Safety

• A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation

  Rashidi, A.

  National Marrow Donor Program

  3/6/19 → 3/30/24

  Project: Research project

  • Peripheral Blood Stem Cell Transplantation
  • Mycophenolic Acid
  • Tacrolimus
  • Methotrexate
  • Cyclophosphamide

• A Multicenter, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of the Combination Therapy of SCY-078 with Voriconazole in Patients with Invasive Pulmonary Aspergillosis (SCYNERGIA)

  Young, J. H.

  SCYNEXIS, INC.

  3/29/19 → 3/30/24

  Project: Research project

  • MK-3118
  • Invasive Pulmonary Aspergillosis
  • Double-Blind Method
  • Safety
  • Therapeutics

• A phase II, open-label study of ONC201 in adults with recurrent high-grade glioma

  Chen, C. C.

  ONCOCEUTICS, INC.

  3/12/19 → 3/30/24

  Project: Research project

  • TIC10 compound
  • Glioma

• Antiplatelet Removal and HemocompatIbility EventS with the HeartMate 3 Pump

  Cogswell, R. J.

  Abbott Laboratories

  3/1/20 → 3/31/24

  Project: Research project

  • pump
  • removal

• Novel statistical methods and tools to integrate multiple endophenotypes and functional annotation data to study the roles of rare variants in complex human diseases using sequencing data

  Wu, B.

  Yale University

  6/1/20 → 3/31/24

  Project: Research project

  • Statistical methods

• A Non-Interventional, Retrospective Study of the Natural History and Routine Clinical Management of Congenital Disorders of Glycosylation (CDG)

  Sarafoglou, K. M.

  CERECOR INC

  3/28/19 → 3/31/24

  Project: Research project

  • Congenital Disorders of Glycosylation
  • Natural History
  • Retrospective Studies

• Healey ALS Platform Trial Task Order #3: Regimen-Specific Appendix B, Verdiperstat

  Walk, D.

  MASSACHUSETTS GENERAL HOSPITAL

  4/6/20 → 3/31/24

  Project: Research project

• Assembly, Targeting, and Regulation of Dynein Motors

  Porter, M. E.

  NIH NIGMS NATL INST OF GENERAL

  4/10/20 → 3/31/24

  Project: Research project

  • Targeting

• A Phase I/II Trial in Patients with Metastatic GastrointestinalEpithelial Cancer Administering Tumor-Infiltrating Lymphocytes in which the GeneEncoding CISH was Inactivated Using the CRISPR/Cas9 System (CPRC # 2019LS002)

  Lou, E.

  INTIMA CAPITAL, LLC

  3/20/19 → 3/31/24

  Project: Research project

  • Clustered Regularly Interspaced Short Palindromic Repeats
  • Gastrointestinal Neoplasms
  • Genes
  • Neoplasms

• Identifying symptomatic and neuroprotective strategies for cerebellar ataxia

  Orr, H. T.

  University of Michigan

  4/15/19 → 3/31/24

  Project: Research project

  • Cerebellar Ataxia

• Healey ALS Platform Trial Task Order #4: Regimen-Specific Appendix C, CNM-Au8

  Walk, D.

  MASSACHUSETTS GENERAL HOSPITAL

  4/6/20 → 3/31/24

  Project: Research project

• Improving primary care providers' ability to communicate about patients' experiences of racism to improve cardiovascular health: a feasibility study

  Cunningham, B. A.

  NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

  4/15/19 → 3/31/24

  Project: Research project

  • Racism
  • Feasibility Studies
  • Primary Health Care
  • Aptitude
  • Health

• Understanding the structural dynamics of TNF receptors

  Sachs, J. N.

  NIH NIGMS NATL INST OF GENERAL

  6/1/19 → 3/31/24

  Project: Research project

  • dynamic structural analysis

• Comparative Medicine and Pathology Training

  McCue, M. E., Brown, D. R., Carlson, C. S. & Carlson, C. S.

  NIH Office of the Director

  4/1/19 → 3/31/24

  Project: Research project

  • Pathology
  • Medicine

• Miniaturized head-mounted device for pan-cortical electro-optical activity monitoring

  Bangalore Kodandaramaiah, S.

  NIH NAT INST OF NEURO DISORDERS & STROKE

  4/15/19 → 3/31/24

  Project: Research project

  • optical activity

• Vermont All Payer Evaluation Accountable Care Organization (ACO) Model

  Worrall, C. A. & Planalp, C.

  National Opinion Research Center

  9/21/18 → 3/31/24

  Project: Research project

  • organization
  • evaluation

• Preventing Seizures and Associated Memory Loss in Alzheimer's Disease by Blocking Tau Interactions with SH3-containing Proteins

  Vossel, K. A.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  8/1/19 → 3/31/24

  Project: Research project

  • Memory Disorders
  • Alzheimer Disease
  • Seizures
  • Proteins

• Deregulation of Long Noncoding RNA in the Pathogenesis of Autosomal Dominant Polycystic Kidney Disease

  Aboudehen, K.

  NIH Natl Inst of Diabetes/Dig/Kidney Dis

  5/15/19 → 3/31/24

  Project: Research project

  • Autosomal Dominant Polycystic Kidney
  • Long Noncoding RNA

• A Phase 3 Trial of ADXS11-001 (NSC #752718) Administered

  Erickson, B. K.

  ADVAXIS, INC.

  9/1/16 → 3/31/24

  Project: Research project

  • Uterine Cervical Neoplasms

• Fully Automated Motion-corrected MR Spectroscopy in Human Brain and Spinal Cord

  Deelchand, D. K., Henry, P., Nestrasil, I. & Terpstra, M.

  NIH NATL INST OF BIOMEDICAL IM

  7/1/20 → 3/31/24

  Project: Research project

  • Spinal Cord
  • Brain

• The effects of parkinsonism and deep brain stimulation on basal ganglia-thalamocortical circuitry during sleep-wake behavior

  Johnson, L. A., Howell, M. J., MacKinnon, C. & Vitek, J. L.

  NIH NAT INST OF NEURO DISORDERS & STROKE

  4/1/19 → 3/31/24

  Project: Research project

  • Deep Brain Stimulation
  • Parkinsonian Disorders
  • Basal Ganglia
  • Sleep

• Soluble aSyn is a modulator of AD pathophysiology

  Lesne, S. E., Araque, A. & Lee, M. K.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  8/15/19 → 3/31/24

  Project: Research project

• Residential Buildings Subject Matter Expert Support

  Huelman, P. H., Cheple, M., Donahue, P. K., Handeen, D., Jacobson, R. E. & Mosiman, G. E.

  National Renewable Energy Laboratory

  4/27/20 → 4/26/24

  Project: Research project

  • residential building