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• A PHASE 2, OPEN-LABEL, SINGLE-ARM, COHORT STUDY TO EVALUATE THE SAFETY, EFFICACY, AND PHARMACOKINETICS OF SPARSENTAN TREATMENT IN PEDIATRIC SUBJECTS WITH SELECTED PROTEINURIC GLOMERULAR DISEASES(EPPIK)

  Rheault, M. N.

  TRAVERE THERAPEUTICS, INC

  4/16/21 → 4/30/26

  Project: Research project

• A Phase 2, Open-label, Randomized, Two-stage Clinical Studyof Alvocidib in Patients with Relapsed/Refractory AcuteMyeloid Leukemia Following Treatment with VenetoclaxCombination Therapy

  Warlick, E. D.

  TOLERO PHARMACEUTICALS, INC.

  3/1/20 → 2/28/25

  Project: Research project

• A Phase 2, Open-Label, Multiple-Dose Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 inPediatric Subjects with Congenital Adrenal Hyperplasia

  Sarafoglou, K. M.

  Neurocrine Biosciences, Inc.

  5/28/19 → 5/31/24

  Project: Research project

• A Phase 2, Open-label, Multinational Clinical Study to E

  Whitley, C. B.

  BIOMARIN PHARMACEUTICAL, INC.

  3/15/12 → 6/4/12

  Project: Research project

• A Phase 2, Open-Label, Multicenter Study of Single-Agent

  Bohjanen, K. A.

  Eli Lilly G.m.b.H.

  10/14/08 → 12/31/11

  Project: Research project

• A Phase 2, Open-Label, Multi-Center, Randomized Trial to

  Lake, J. R.

  LIFECYCLE PHARMA

  9/10/08 → 2/10/12

  Project: Research project

• A Phase 2, Open-Label, Basket Study of Atrasentan inPatients with Proteinuric Glomerular Diseases

  Rheault, M. N.

  CHINOOK THERAPEUTICS, INC

  1/29/21 → 1/31/26

  Project: Research project

• A Phase 2, Multiple-Dose, Dose-Escalation Study

  Sarafoglou, K. M.

  SPRUCE BIOSCIENCES, INC.

  5/1/17 → 5/30/22

  Project: Research project

• A Phase 2, Multicenter Study to Assess the Safety and Ef

  Domingo-Musibay, E.

  IOVANCE BIOTHERAPEUTICS

  5/1/17 → 12/31/24

  Project: Research project

• A Phase 2, Multi-Center ... Study to Assess Safety and I

  Hatsukami, D. K., Allen, S. S. & Jensen, J. A.

  NABI

  4/19/06 → 9/30/08

  Project: Research project

• A Phase 2, Multicenter,Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety and Efficacy of Risankizumab inAdult Subjects with Moderate to Severe Hidradenitis Suppurativa

  Goldfarb, N.

  AbbVie

  8/8/19 → 8/30/24

  Project: Research project

• A Phase 2, multicenter, randomized, placebo-controlled, doubleblind study in patients with acquired thrombotic thrombocytopenic purpura (aTTP) to evaluate the pharmacokinetics, safety, and efficacy of rADAMTS-13 (SHP655) administered in addition to stand

  Datta, Y. H. & Mazepa, M.

  Baxalta US Inc.

  7/1/19 → 7/30/24

  Project: Research project

• A Phase 2, Multi-Center, Randomized, Placebo-Controlled

  Billings, J. L.

  Seattle Children's Hospital

  9/1/13 → 6/30/18

  Project: Research project

• A Phase 2, Multi-Center, Randomized, Double-Blind, Place

  Billings, J. L.

  MPEX PHARMACEUTICALS, INC.

  9/1/08 → 8/31/10

  Project: Research project

• A phase 2, multi-center, randomized, double-blind, place

  Humar, A. & Kandaswamy, R.

  DOMPE S.P.A

  4/12/05 → 12/31/08

  Project: Research project

• A Phase 2, Multicenter, Randomized, Double-Blind, Parall

  Crow, S. J. & Peterson, C. B.

  Shire Development Inc.

  5/9/11 → 6/13/12

  Project: Research project

• A Phase 2, Multicenter, Randomized, Double-Blind, Contro

  Hordinsky, M. K.

  INTREPID THERAPEUTICS, INC.

  5/27/14 → 12/31/16

  Project: Research project

• A Phase 2, Multicenter, Open-Label Study to Investigate

  Lake, J. R.

  Gilead Sciences, Inc.

  7/12/13 → 12/31/15

  Project: Research project

• A Phase 2, Multi-Center, Open-Label Study to Evaluate Long-term Safety and Efficacy of CXA-10 in Subjects with Pulmonary Arterial Hypertension on Stable Background Therapy: Extension to Study CXA-10-301 (Complexa CXA-10-2302 - PRIMEx Open Label Extension

  Prins, K. W.

  COMPLEXA INC

  2/1/20 → 2/28/23

  Project: Research project

• A Phase 2, Multicenter, Open-Label, Single Arm, Two-Stag

  Skubitz, K.

  Celgene Corporation

  2/9/08 → 12/31/13

  Project: Research project

• A Phase 2, Multicenter, Open Label, Randomized Trial of

  Dudek, A. Z.

  Amgen Inc.

  1/8/07 → 12/31/10

  Project: Research project

• A Phase 2, Multi-Center, Open-label, Randomized, Paralle

  Warlick, E. D.

  Celgene Corporation

  10/17/12 → 12/31/17

  Project: Research project

• A Phase 2, multicenter, open-label, non-randomized, proof-of-concept study evaluating the efficacy, safety, and tolerability of BIVV020 in adults with chronic inflammatory demyelinating polyneuropathy (CIDP)

  Allen, J. A.

  SANOFI-AVENTIS US

  1/1/22 → 12/31/27

  Project: Research project

• A Phase 2, Multicenter, Multinational, Randomized, Doubl

  Kim, H. J. & Whelan, T.

  Janssen Biotech, Inc.

  12/30/08 → 12/26/12

  Project: Research project

• A Phase 2, Double-Blind, Randomized Safety And Efficacy

  Afrin, L. B.

  PFIZER, INC.

  7/1/15 → 6/30/16

  Project: Research project

• A Phase 2, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of Sotaterceptversus Placebo for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension(Cpc-PH) due to Heart Failure with Preserved Ejection

  Thenappan, T.

  ACCELERON PHARMA INC.

  9/1/21 → 9/30/25

  Project: Research project

• A Phase 2, double-blind, placebo-controlled, randomized,

  Tuite, P. J.

  SYNEOS HEALTH, INC

  6/15/05 → 12/15/06

  Project: Research project

• A Phase 2, Double-Blind, Multi-Center, Randomized Study

  Lake, J. R.

  Gilead Sciences, Inc.

  12/31/05 → 12/12/12

  Project: Research project

• A Phase 2, Dose-Ranging, Randomized, Double-Blind,Placeb

  Thenappan, T.

  Gilead Sciences, Inc.

  7/25/14 → 7/24/19

  Project: Research project

• A Phase 1 Study to Evaluate the Safety, Tolerability

  Moran, A., Bellin, M. D., Nathan, B. M. & Sunni, M.

  PFIZER, INC.

  4/1/14 → 9/30/18

  Project: Research project

• A Phase 1 Study of the VEGF Receptor Tyrosine Kinase

  Greengard, E. G.

  Children's Hospital of Philadelphia

  7/30/14 → 2/28/17

  Project: Research project

• A Phase 1 Study of the Clinical and Immunologic

  Holtan, S. G.

  Fred Hutchinson Cancer Research Center

  7/1/16 → 12/31/19

  Project: Research project

• A Phase 1 Study of AC220 (ASP2689) as Maintenance Therap

  Ustun, C.

  Astellas Pharma US, Inc.

  4/1/12 → 9/30/17

  Project: Research project

• A Phase 1 Study in Patients Supporting Use of IV TPM for

  Cloyd, J. C., Brundage, R., Kriel, R. L. & Leppik, I. E.

  DHHS FOOD & DRUG ADMINISTRATION (FDA)

  9/20/08 → 6/30/10

  Project: Research project

• A Phase 1 Study Evaluating the Safety,Pharmacokinetics, and Anti-Tumor Activity ofABBV-321 in Subjects with Advanced Solid TumorsAssociated with Overexpression of the EpidermalGrowth Factor Receptor (EGFR)

  Patel, M. R.

  AbbVie

  5/26/20 → 6/1/26

  Project: Research project

• A Phase 1 Safety and Dose-Finding Study of a Human Insul

  Whitley, C. B.

  ARMAGEN, INC.

  10/5/15 → 4/30/18

  Project: Research project

• A Phase 1 Open Label Dose Escalation Trial of QPI-1007 D

  Lee, M.

  Quark Pharmaceuticals, Inc.

  2/15/10 → 2/14/13

  Project: Research project

• A Phase 1 Multicenter, Open-Label Study to Evaluate the

  Molitor, J. A.

  MedImmune, LLC

  3/12/09 → 9/28/09

  Project: Research project

• A PHASE 1 DOSE ESCALATION STUDY EVALUATING THE SAFETY AN

  Beckwith, H. C.

  PFIZER, INC.

  9/22/15 → 9/21/19

  Project: Research project

• A Phase 1 Dose Escalation and Cohort Expansion Study of the Safety and Efficacy of Anti-CD19 AllogeneicCRISPR-Cas9???Engineered T Cells (CTX110) in Subjects With Relapsed or Refractory B Cell Malignancies

  Maakaron, J.

  CRISPR THERAPEUTICS, INC

  6/1/20 → 5/31/25

  Project: Research project

• A Phase 1b Study to Evaluate the Safety, Tolerability and Drug-Drug Interactions of ANX005 and Intravenous Immunoglobulin (IVIg) in Subjects with Guillain-Barre Syndrome

  Allen, J. A.

  ANNEXON, INC

  10/1/19 → 9/30/22

  Project: Research project

• A Phase 1b Study of Venetoclax and Capecitabine In Subjects with Hormone Receptor-Positive, HER2- Negative Locally Advanced or Metastatic Breast Cancer Who Experienced Disease Progression During or After CDK4/6 Inhibitor Therapy

  Potter, D. A.

  AbbVie

  1/22/20 → 1/31/25

  Project: Research project

• A Phase 1b Study of Venetoclax and Capecitabine In Subjects with Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Experienced Disease Progression During orAfter CDK4/6 Inhibitor Therapy

  Potter, D. A.

  AbbVie

  1/22/20 → 1/31/25

  Project: Research project

• A PHASE 1B STUDY OF NIKTR-102 IN COMBINATION WITH PEGYLA

  Downs, L. S.

  NEKTAR THERAPEUTICS

  10/1/11 → 9/30/12

  Project: Research project

• A Phase 1b Study of LY573636-sodium in Combination with

  Dudek, A. Z.

  Eli Lilly G.m.b.H.

  4/1/08 → 12/31/13

  Project: Research project

• A Phase 1b Randomized, Double Blinded, Placebo Controlled, Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single Doses of ARCT-810 in Clinically Stable Patients with Ornithine Transcarbamylase Deficiency

  Berry, S. A.

  ARCTURUS THERAPEUTICS, INC

  6/1/20 → 6/30/25

  Project: Research project

• A phase 1b dose-escalation and dose-expansion study of e

  Antonarakis, E., Gupta, S. & Rao, A.

  Seattle Genetics, Inc.

  12/1/17 → 12/31/23

  Project: Research project

• A Phase 1b/2 Trial of Hu5F9-G4 in Combination with Rituximab in Patients with Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

  Maakaron, J. & Pongas, G.

  FORTY SEVEN, INC.

  12/1/18 → 11/30/22

  Project: Research project

• A Phase 1b/2 Trial of AMG 386 in Combination with Pemetr

  Fujioka, N.

  Amgen Inc.

  6/1/13 → 3/31/14

  Project: Research project

• A phase 1B/2 study to evaluate safety and anti-tumor act

  Ryan, C. & Gupta, S.

  PFIZER, INC.

  11/1/17 → 11/30/22

  Project: Research project