Find Research Projects

Search results

• Mechanisms of mTORC1 signaling to protein degradation pathways

  Kim, D.

  NIH NIGMS NATL INST OF GENERAL

  3/8/19 → 2/29/24

  Project: Research project

  • Mechanistic Target of Rapamycin Complex 1
  • Proteolysis

• Detection and Activation of CD4+ T cells with Low Affinity TCRs

  Jenkins, M.

  NIH Nat'l Inst of Allergy & Infect Dis

  3/1/19 → 2/29/24

  Project: Research project

  • T-Lymphocytes

• CAREER: Scaling-up effects of biodiversity on ecosystem productivity: from local communities to landscapes

  Isbell, F.

  National Science Foundation

  3/1/19 → 2/29/24

  Project: Research project

  • biodiversity
  • productivity
  • ecosystem
  • effect

• Neurobiology of Female Sexual Desire

  Meisel, R. L.

  NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

  3/15/19 → 2/29/24

  Project: Research project

  • neurosciences

• A Phase III Randomized Placebo-Controlled Study to Examine the Efficacy and Safety of DAS181 for theTreatment of Lower Respiratory Tract Parainfluenza Infection in Immunocompromised Subjects

  Young, J. H.

  ANSUN BIOPHARMA, INC.

  2/6/19 → 2/29/24

  Project: Research project

  • DAS181
  • Paramyxoviridae Infections
  • Respiratory Tract Infections
  • Placebos
  • Safety

• Perennial crops to improve soil health and sustain yields for climate extremes

  Gutknecht, J. L., Fernandez, C. W., Hunter, M. C., Jungers, J. M. & Sheaffer, C. C.

  USDA Nat'l Inst. of Food & Agriculture

  3/1/19 → 2/29/24

  Project: Research project

  • soil quality
  • climate
  • crops

• Development and Validation of a Gene Expression Assay to Predict the Risk of Recurrence Disease in Cutaneous Squamous Cell Carcinoma

  Maher, I.

  CASTLE BIOSCIENCES, INC.

  2/6/19 → 2/29/24

  Project: Research project

  • Squamous Cell Carcinoma
  • Gene Expression
  • Recurrence
  • Skin

• Deep sequencing, phenotyping, and imputation in large-scale biobanks: A novel and cost-effective framework to identify rare mutations associated with addiction

  Vrieze, S. I., Albert, F. W. & Lee, A. M.

  NIH NIDA NATL INST ON DRUG AB

  5/1/19 → 2/29/24

  Project: Research project

  • High-Throughput Nucleotide Sequencing
  • Costs and Cost Analysis
  • Mutation

• Can tDCS accelerate and sustain the cognitive benefits of targeted cognitive training in schizophrenia

  Ramsay, I. S.

  NIH Nat'l Institute of Mental Health

  3/5/19 → 2/28/24

  Project: Research project

  • Schizophrenia

• A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to EvaluateEfficacy and Safety of Lenabasum in Dermatomyositis

  Molitor, J. A.

  CORBUS PHARMACEUTICALS, INC.

  2/26/19 → 2/28/24

  Project: Research project

  • Placebos
  • Safety

• A MULTICENTER, LONGITUDINAL, PROSPECTIVE, PHARMACOKINETIC,PHASE 1B STUDY IN WOMEN WITH CHRONIC INFLAMMATORY DISEASES TREATED WITHCIMZIA® (CERTOLIZUMAB PEGOL) DURING PREGNANCY

  Shmidt, E.

  UCB Pharma S.A.

  2/26/20 → 2/28/24

  Project: Research project

  • Certolizumab Pegol
  • Pharmacokinetics
  • Chronic Disease
  • Pregnancy

• Prospective, International, Multi-Center, Randomized Clinical Investigation Of TransMedics Organ Care System (OCS Lung) For Lung Preservation And Transplantation

  Huddleston, S. J.

  TRANSMEDICS, INC.

  3/1/19 → 2/28/24

  Project: Research project

  • Transplantation
  • Lung

• Momentum 3 Pivotal Cohort Extended Follow-up Post-Approval Study

  John, R.

  Abbott Laboratories

  3/1/19 → 2/28/24

  Project: Research project

• OCS Lung EXPAND Post-Approval Study - EXPAND Follow-Up Data Collection

  Huddleston, S. J.

  TRANSMEDICS, INC.

  3/8/19 → 2/28/24

  Project: Research project

  • Lung

• A Phase II Single-Arm Study of Therapeutic Iobenguane (131I) For Relapsed, High-Risk Neuroblastoma Subjects (OPTIMUM Trial)PROTOCOL MIBG 2014-01

  Greengard, E. G.

  JUBILANT DRAXLMAGE INC

  2/1/19 → 2/28/24

  Project: Research project

  • 3-Iodobenzylguanidine
  • Neuroblastoma
  • Therapeutics

• A Comparison of Tube and Gel Technology for anti-D titer testing

  Cohn, C. S.

  ORTHO-CLINICAL DIAGNOSTICS, INC.

  2/17/20 → 2/16/24

  Project: Research project

  • gels
  • tubes

• Genetic Factors of Birth Defects-Genomics Testing

  Tsai, M. Y. & Pankratz, N. D.

  National Institutes of Health

  5/10/17 → 2/9/24

  Project: Research project

  • Genomics

• Basal Ganglia Cortical Coupling and Connectivity Changes in PD and DBS

  Vitek, J. L., Eberly, L. E., Harel, N., Johnson, L. A. & Johnson, M. D.

  NIH NAT INST OF NEURO DISORDERS & STROKE

  3/1/19 → 1/31/24

  Project: Research project

  • Basal Ganglia

• Role of nucleosome dynamics in epigenetic inheritance

  Yu, C.

  NIH NIGMS NATL INST OF GENERAL

  2/1/20 → 1/31/24

  Project: Research project

  • Nucleosomes
  • Epigenomics

• MRI based presymptomatic prediction of ASD

  Elison, J. T.

  Washington University St. Louis

  2/1/20 → 1/31/24

  Project: Research project

• An Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study to Evaluate the Safety and Efficacy of Danaparoid vs Argatroban in Treatment of Subjects with Acute HIT (HITSOVA study)

  Shah, S. & Mazepa, M.

  ERGOMED CLINICAL RESEARCH, INC

  1/10/19 → 1/31/24

  Project: Research project

  • danaparoid
  • argatroban
  • Safety

• Open-Label Study of ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), AlopeciaUniversalis (AU) and Alopecia Totalis (AT)

  Hordinsky, M. K.

  ACLARIS THERAPEUTICS, INC

  1/4/19 → 1/31/24

  Project: Research project

• Mechanical Circulatory Support PRODUCT SURVEILLANCE REGISTRY (PSR) PLATFORM BASE CIP

  John, R.

  Medtronic, Inc.

  2/1/19 → 1/31/24

  Project: Research project

  • Registries

• The effect of inflammation and damage to lymph node structures on durable protective immunity following vaccination

  Schacker, T. W., Beilman, G. J., Chipman, J. G., Helgeson, E. S., Jenkins, M., Khoruts, A. & Reilly, C. S.

  NIH Nat'l Inst of Allergy & Infect Dis

  2/25/19 → 1/31/24

  Project: Research project

  • vaccination
  • immunity
  • damage
  • effect

• Combination therapy with IFN expressing oncolytic adenovirus for pancreatic cancer

  Yamamoto, M.

  NIH NATIONAL CANCER INSTITUTE (NCI)

  2/5/19 → 1/31/24

  Project: Research project

  • Adenoviridae
  • Pancreatic Neoplasms
  • Neoplasms
  • Therapeutics

• A Phase 2 Open-label, Multicenter, Randomized, Multidrug Platform Study of Neoadjuvant DurvalumabAlone or in Combination with Novel Agents in Subjects with Resectable, Early-stage (I [> 2 cm] to IIIA N0-1)Non-small Cell Lung Cancer (NeoCOAST)

  Kratzke, R. A.

  MedImmune, LLC

  1/23/19 → 1/31/24

  Project: Research project

  • durvalumab
  • Non-Small Cell Lung Carcinoma

• SPR001-202: A 3-Month Phase 2 Study to Evaluate the Safety and Efficacy of SPR001 in Subjects with Classic Congenital Adrenal Hyperplasia

  Sarafoglou, K. M.

  SPRUCE BIOSCIENCES, INC.

  1/14/19 → 1/31/24

  Project: Research project

  • Congenital Adrenal Hyperplasia
  • Safety

• RNA methylation and mesenchymal stem cell differentiation

  Kikyo, N. J.

  NIH NIGMS NATL INST OF GENERAL

  3/15/20 → 1/31/24

  Project: Research project

  • Methylation
  • Mesenchymal Stem Cells
  • Cell Differentiation
  • RNA

• Peripheral nerve recording, analysis, and modulation for neural communication and control

  Yang, Z.

  National Science Foundation

  2/15/19 → 1/31/24

  Project: Research project

  • Peripheral Nerves

• Circuit Specific Electrical Brain Stimulation

  Widge, A. S.

  NIH Nat'l Institute of Mental Health

  4/1/19 → 1/31/24

  Project: Research project

  • Deep Brain Stimulation

• Discovery of New Antibacterial Targets: Probes and Inhibitors of Histidine Kinase Proteins

  Carlson, E. E., Goodpaster, J. D. & Hunter, R. C.

  NIH NIGMS NATL INST OF GENERAL

  4/1/20 → 1/31/24

  Project: Research project

  • Histidine Kinase

• Technology to Realize the Full Potential of UHF MRI

  Ugurbil, K., Adriany, G., Akcakaya, M., Auerbach, E. J., Bolan, P. J., Chen, W., Eryaman, Y., Garwood, M., Ghose, G. M., Hayden, B. Y., Mangia, S., Marjanska, M., Metzger, G., Michaeli, S., Moeller, S., Van de Moortele, P. & Wu, X.

  NIH NATL INST OF BIOMEDICAL IM

  2/1/19 → 1/31/24

  Project: Research project

• Cancer Center Support Grant

  Yee, D., AbuSalah, A. M., Basu, S., Beckman, K. B., Bielinsky, A. K., Cooley, S. A., De For, T. E., Falconer, S. N., Felices, M., Griffin, T. J., Hallstrom, T. C., Hatsukami, D. K., Hendrickson, E. A., Hirsch, B. A., Joseph, A. M., Kirstein, M. N., Konety, B. R., Koopmeiners, J., Kuntz, K. M., Lange, C. A., Largaespada, D. A., Le, C. T., LeBeau, A., Lindgren, B. R., Luo, X., Mc Carthy, J. B., McKenna, D. H., Miller, J. S., Moriarity, B. S., Nelson, H. H., O'Sullivan, G., Ondrey, F. G., Pennell, C. A., Petersen, A. J., Peterson, L. A., Peterson, B. A., Sarver, A. L., Shimizu, Y., Siegfried, J. M., Temiz, N. A., Turesky, R., Vogel, R., Wagner, J. E., Wang, J., Weigel, B. J., Weisdorf, D. J., Woo, J. & Yamamoto, M.

  NIH NATIONAL CANCER INSTITUTE (NCI)

  2/1/19 → 1/31/24

  Project: Research project

• Connectome Coordination Facility II

  Yacoub, E.

  Washington University St. Louis

  4/15/20 → 1/31/24

  Project: Research project

• A Phase 3 Study of Lenti-D Drug Product After Myeloablative Conditioning Using Busulfan and Fludarabine in Subjects ≤ 17 Years of Age With Cerebral Adrenoleukodystrophy (CALD)

  Orchard, P. J., Gupta, A. O., Kenney-Jung, D. L. & Lund, T. C.

  Bluebird Bio, Inc.

  2/1/19 → 1/31/24

  Project: Research project

  • Adrenoleukodystrophy
  • Busulfan
  • fludarabine
  • Pharmaceutical Preparations

• RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SAFETY, TOLERABILITY, AND EFFICACY OF RV521 IN THE TREATMENT OF ADULT SUBJECTS WHO HAVE UNDERGONE HEMATOPOIETIC CELL TRANSPLANTATION (HCT) WITH A DOCUMENTED UPPER RESPIRATORY TRACTINFECTION (URT)

  Young, J. H.

  REVIRAL LTD

  6/24/20 → 1/31/24

  Project: Research project

  • Cell Transplantation
  • Respiratory Tract Infections
  • Placebos
  • Safety
  • Therapeutics

• SynerFuse Spinal Fusion and Neuromodulation Proof of ConceptStudy

  Park, M. C.

  SYNERFUSE, INC.

  2/1/20 → 1/31/24

  Project: Research project

  • Fusion

• Regulation of the Immune Response to Plasmodium by IL-10 Producing Natural Killer Cells

  Hamilton Hart, S. E. & Hart, G. T.

  NIH Nat'l Inst of Allergy & Infect Dis

  2/8/19 → 1/31/24

  Project: Research project

  • natural killer cells
  • interleukin-10
  • Plasmodium
  • immune response

• Targeting Cellular Senescence to Extend Healthspan

  Robbins, P. D. & Niedernhofer, L. J.

  Mayo Clinic

  6/1/19 → 1/31/24

  Project: Research project

• Interaction of estrogen, age, and activity on musculoskeletal strength in females

  Lowe, D. A.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  5/1/19 → 1/31/24

  Project: Research project

  • interaction

• Immune cells as a driver of cell non-autonomous aging

  Niedernhofer, L. J., Arriaga, E., Robbins, P. D. & Stromnes, I. M.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  4/1/19 → 1/31/24

  Project: Research project

  • Aging of materials

• Chromatin regions, genes and pathways that confer susceptibility to chemical-induced DNA damage

  Tretyakova, N. Y.

  TEXAS A&M UNIVERSITY

  2/1/19 → 1/31/24

  Project: Research project

  • DNA damage
  • chromatin
  • genes

• Gut Microbiota and Effect on Immune Suppressants in Transplantation

  Staley, C. M.

  HENNEPIN HEALTHCARE RESEARCH INSTITUTE

  8/1/19 → 1/31/24

  Project: Research project

  • intestinal microorganisms

• CD16/IL-15/CD33 (161533) Tri specific Killer Engagers (TriKEs) for the Treatment of High Risk Myelodysplastic Syndromes, Refractory/Relapsed Acute Myeloid Leukemia and Advanced Systemic Mastocytosis

  Warlick, E. D.

  GT BIOPHARMA, INC

  6/1/17 → 1/31/24

  Project: Research project

  • Systemic Mastocytosis
  • Interleukin-15
  • Myelodysplastic Syndromes
  • Acute Myeloid Leukemia

• AMP-Kinase as a target for neuroprotection in AD

  Lee, M. K., Lesne, S. E. & Liao, D.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  2/15/19 → 1/31/24

  Project: Research project

• A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease Therapy

  Sudel, B.

  TARGET PHARMASOLUTIONS, INC

  1/23/19 → 1/31/24

  Project: Research project

  • Inflammatory Bowel Diseases
  • Longitudinal Studies
  • Observational Studies
  • Therapeutics

• Increasing Multiculturalism in Veterinary Medicine: Peer Mentoring and Portfolio Building

  Rutherford, M. S., Lorenz, K. W. & Molgaard, L. K.

  USDA Nat'l Inst. of Food & Agriculture

  1/15/19 → 1/14/24

  Project: Research project

  • mentoring
  • peers
  • veterinary medicine

• A One-Year, Multicenter, Non-Interventional, Follow-Up,

  Bellin, M. D.

  VIACYTE, INC.

  2/1/18 → 12/31/23

  Project: Research project

  • Safety

• The John Paul Stevens Public Interest Fellowship Program 2021-2023

  Furst, A. M.

  The John Paul Stevens Fellowship Fdn.

  1/1/21 → 12/31/23

  Project: Research project

  • public interest

• Dynamics of granular raft on a moving interface: structure and property

  Lee, S.

  National Science Foundation

  1/1/21 → 12/31/23

  Project: Research project

  • rafts