19992021

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia

Sachs, K., Sarver, A. L., Noble-Orcutt, K. E., LaRue, R. S., Antony, M. L., Chang, D., Lee, Y., Navis, C. M., Hillesheim, A. L., Nykaza, I. R., Ha, N. A., Hansen, C. J., Karadag, F. K., Bergerson, R. J., Verneris, M. R., Meredith, M. M., Schomaker, M. L., Linden, M. A., Myers, C. L., Largaespada, D. A. & 1 others, Sachs, Z., Feb 1 2020, In : Cancer Research. 80, 3, p. 458-470 13 p.

Research output: Contribution to journalArticle

2019

Multiomic Profiling of Tyrosine Kinase Inhibitor-Resistant K562 Cells Suggests Metabolic Reprogramming to Promote Cell Survival

Noel, B. M., Ouellette, S. B., Marholz, L., Dickey, D., Navis, C., Yang, T. Y., Nguyen, V., Parker, S. J., Bernlohr, D., Sachs, Z. & Parker, L. L., Apr 5 2019, In : Journal of Proteome Research. 18, 4, p. 1842-1856 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

NRASG12V-Mediated Self-Renewal Signaling in Self-Renewing AML Stem Cells.

ANTONY, MARIE. LUE., Noble, K. E., Sachs, K., Hillesheim, A. L., Chang, D., Mohei, H., Pamukcuoglu, M., Largaespada, D. A. & Sachs, Z., Nov 29 2018, In : Blood.

Research output: Contribution to journalArticle

2017

Buccal epithelial cells display somatic, bone marrow-derived CALR mutation

Gilles, S. R., Baughn, L. B., Schomaker, M. L., Courville, E. L., Nelson, A. C. & Sachs, Z., Nov 28 2017, In : Blood Advances. 1, 25, p. 2302-2306 5 p.

Research output: Contribution to journalArticle

Open Access

Human melanoma-derived extracellular vesicles regulate dendritic cell maturation

Maus, R. L. G., Jakub, J. W., Nevala, W. K., Christensen, T. A., Noble-Orcutt, K., Sachs, Z., Hieken, T. J. & Markovic, S. N., Mar 29 2017, In : Frontiers in immunology. 8, MAR, 358.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Novel single-cell technologies in acute myeloid leukemia research

Gupta, S. D. & Sachs, Z., Nov 2017, In : Translational Research. 189, p. 123-135 13 p.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations
2016

Double- and triple-hit lymphomas can present with features suggestive of immaturity, including TdT expression, and create diagnostic challenges

Moench, L., Sachs, Z., Aasen, G., Dolan, M., Dayton, V. & Courville, E. L., Nov 1 2016, In : Leukemia and Lymphoma. 57, 11, p. 2626-2635 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress

Yun, Y. S., Kim, K. H., Tschida, B., Sachs, Z., Noble-Orcutt, K. E., Moriarity, B. S., Ai, T., Ding, R., Williams, J., Chen, L., Largaespada, D. & Kim, D. H., Feb 18 2016, In : Molecular Cell. 61, 4, p. 625-639 15 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Novel disease burden assessment predicts allogeneic transplantation outcomes in myelodysplastic syndrome

Trottier, B. J., Sachs, Z., De For, T. E., Shune, L., Dolan, M. M., Weisdorf, D. J., Ustun, C. & Warlick, E. D., Feb 1 2016, In : Bone marrow transplantation. 51, 2, p. 199-204 6 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency

Sachs, Z., Been, R. A., Decoursin, K. J., Nguyen, H. T., Mohd Hassan, N. A., Noble-Orcutt, K. E., Eckfeldt, C. E., Pomeroy, E. J., Diaz-Flores, E., Geurts, J. L., Diers, M. D., Hasz, D. E., Morgan, K. J., Macmillan, M. L., Shannon, K. M., Largaespada, D. A. & Wiesner, S. M., Sep 30 2016, In : Haematologica. 101, 10, p. 1190-1199 10 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

The role of the proteasome in AML

Csizmar, C. M., Kim, D. H. & Sachs, Z., Dec 2 2016, In : Blood cancer journal. 6, 12, p. e503

Research output: Contribution to journalReview article

Open Access
18 Scopus citations
2015
15 Scopus citations

Standardized synoptic reports for plasma cell neoplasms: Integration of laboratory and clinical data

Courville, E. L., Sachs, Z. & Linden, M. A., Jan 1 2015, Plasma Cell Neoplasms: A Morphologic, Cytogenetic and Immunophenotypic Approach. Springer International Publishing, p. 143-149 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues

Kempema, A. M., Widen, J. C., Hexum, J. K., Andrews, T. E., Wang, D., Rathe, S. K., Meece, F. A., Noble, K. E., Sachs, Z., Largaespada, D. A. & Harki, D. A., Jul 23 2015, In : Bioorganic and Medicinal Chemistry. 23, 15, p. 4737-4745 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia

Sachs, Z., LaRue, R. S., Nguyen, H. T., Sachs, K., Noble, K. E., Hassan, N. A. M., Diaz-Flores, E., Rathe, S. K., Sarver, A. L., Bendall, S. C., Ha, N. A., Diers, M. D., Nolan, G. P., Shannon, K. M. & Largaespada, D. A., Nov 20 2014, In : Blood. 124, 22, p. 3274-3283 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Use of sorafenib for post-transplant relapse in FLT3/ITD-positive acute myelogenous leukemia: Maturation induction and cytotoxic effect

Liegel, J., Courville, E., Sachs, Z. & Ustun, C., Nov 1 2014, In : Haematologica. 99, 11, p. e222-e224

Research output: Contribution to journalLetter

14 Scopus citations

Utilization of translational bioinformatics to identify novel biomarkers of bortezomib resistance in multiple myeloma

Fall, D. J., Stessman, H., Patel, S. S., Sachs, Z., Van Ness, B. G., Baughn, L. B. & Linden, M. A., Jan 1 2014, In : Journal of Cancer. 5, 9, p. 720-727 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Lethal small bowel necrosis due to aspergillosis during acute promyelocytic leukemia induction

Lunde, L. E., Chuang, C., Linden, M. A., Williams, S. A., Sachs, Z., Cayci, Z., Young, J. A. H. & Ustun, C., Apr 1 2013, In : American Journal of Hematology. 88, 4, p. 329-332 4 p.

Research output: Contribution to journalComment/debate

2 Scopus citations
2004

p16Ink4a Interferes with Abelson Virus Transformation by Enhancing Apoptosis

Sachs, Z., Sharpless, N. E., DePinho, R. A. & Rosenberg, N., Apr 1 2004, In : Journal of virology. 78, 7, p. 3304-3311 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2000

Loss of heterozygosity at the Ink4a/Arf locus facilitates Abelson virus transformation of pre-B cells

Mostecki, J., Halgren, A., Radfar, A., Sachs, Z., Ravitz, J., Thome, K. C. & Rosenberg, N., Jan 1 2000, In : Journal of virology. 74, 20, p. 9479-9487 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
1999

Cortically driven Fos induction in the striatum is amplified by local dopamine D2-class receptor blockade

Berretta, S., Sachs, Z. & Graybiel, A. M., Dec 1 1999, In : European Journal of Neuroscience. 11, 12, p. 4309-4319 11 p.

Research output: Contribution to journalArticle

28 Scopus citations