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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting TP53 mutant AML stem cells by suppressing NFkB
Sachs, Z. (PI)
AMERICAN SOCIETY OF HEMATOLOGY
7/1/23 → 6/30/25
Project: Research project
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The impact of SL-401 on the molecular mechanisms of self-renewal in TP53 mutant AML
Sachs, Z. (PI)
5/12/20 → 5/11/22
Project: Research project
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Molecular mechanisms of leukemia stem cell persistence i
Sachs, Z. (PI) & Largaespada, D. A. (CoI)
7/1/16 → 6/30/21
Project: Research project
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DEAPR: Differential Expression and Pathway Ranking Tool Demonstrates NRASG12V and NRASG12D Mutations Have Differing Effects in THP-1 Cells
Rathe, S., White, J. P., Sachs, Z. & Largaespada, D. A., Feb 2025, In: Cancers. 17, 3, 467.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia
Millman, S. E., Chaves-Perez, A., Janaki-Raman, S., Ho, Y. J., Morris, J. P., Narendra, V., Chen, C. C., Jackson, B. T., Yashinskie, J. J., Mezzadra, R., Devine, T. I., Barthet, V. J. A., Saoi, M., Baslan, T., Tian, S., Sachs, Z., Finley, L. W. S., Cross, J. R. & Lowe, S. W., Mar 27 2025, In: Blood. 145, 13, p. 1422-1436 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Machine learning analysis of gene expression reveals TP53 Mutant-like AML with wild type TP53 and poor prognosis
Lee, Y., Baughn, L. B., Myers, C. L. & Sachs, Z., Dec 2024, In: Blood cancer journal. 14, 1, 80.Research output: Contribution to journal › Letter › peer-review
Open Access3 Scopus citations -
Patients with TP53-Mutated Acute Myeloid Leukemia Receiving Intensive Induction Therapy Have Superior Outcomes Due to a Higher Rate of Salvage Therapy: A Single Institution, Retrospective Study
Sumransub, N., Steinwand, G. K., Cordner, K., Lee, Y., Cao, Q., Allred, J., Bachanova, V., Juckett, M., Eckfeldt, C., Maakaron, J. E., Tracy, S. I., Ramesh, V., Nelson, A. C., Yohe, S. & Sachs, Z., Aug 2024, In: Cancers. 16, 16, 2784.Research output: Contribution to journal › Article › peer-review
Open Access -
R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription–Replication Conflicts
Liu, Z. S., Sinha, S., Bannister, M., Song, A., Arriaga-Gomez, E., McKeeken, A. J., Bonner, E. A., Hanson, B. K., Sarchi, M., Takashima, K., Zong, D., Corral, V. M., Nguyen, E., Yoo, J., Chiraphapphaiboon, W., Leibson, C., McMahon, M. C., Rai, S., Swisher, E. M. & Sachs, Z. & 10 others, , 2024, In: Cancer Research. 84, 4, p. 577-597 21 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations
Press/Media
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Celebrating cancer 'ResearcHERS' and addressing the challenges
3/5/20
1 item of Media coverage
Press/Media: Expert Comment or Interview