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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Development of HIV capsid-targeting antivirals that affect immune response by modulating capsid stability and have improved resistance profiles
6/24/21 → 5/31/26
Project: Research project
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Discovery and development of novel anti-HCMV agents targeting the UL89 terminase protein
Geraghty, R. J., Aihara, H., Wang, Z. & Xie, J.
NIH Nat'l Inst of Allergy & Infect Dis
1/25/19 → 12/31/23
Project: Research project
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4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease
He, T., Edwards, T. C., Xie, J., Aihara, H., Geraghty, R. J. & Wang, Z., Apr 14 2022, In: Journal of medicinal chemistry. 65, 7, p. 5830-5849 20 p.Research output: Contribution to journal › Article › peer-review
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4-benzylideneisoquinoline-1,3(2H,4H)-diones as tyrosyl DNA phosphodiesterase 2 (TDP2) inhibitors
Senaweera, S., He, T., Cui, H., Aihara, H. & Wang, Z., Feb 2021, In: Medicinal Chemistry Research. 30, 2, p. 371-386 16 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Can remdesivir and its parent nucleoside GS-441524 be potential oral drugs? An in vitro and in vivo DMPK assessment
Xie, J. & Wang, Z., Jun 2021, In: Acta Pharmaceutica Sinica B. 11, 6, p. 1607-1616 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Design, synthesis and characterization of HIV-1 ca-targeting small molecules: Conformational restriction of PF74
Sahani, R. L., Diana-Rivero, R., Vernekar, S. K. V., Wang, L., Du, H., Zhang, H., Castaner, A. E., Casey, M. C., Kirby, K. A., Tedbury, P. R., Xie, J., Sarafianos, S. G. & Wang, Z., Mar 2021, In: Viruses. 13, 3, 479.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Discovery of N-benzyl hydroxypyridone carboxamides as a novel and potent antiviral chemotype against human cytomegalovirus (HCMV)
Senaweera, S., Edwards, T. C., Kankanala, J., Wang, Y., Sahani, R. L., Xie, J., Geraghty, R. J. & Wang, Z., Aug 1 2021, In: Acta Pharmaceutica Sinica B. 12, 4, p. 1671-1684 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations