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Personal profile

Research interests

  • Vaccine adjuvant
  • DNA adduct
  • Adductomics
  • kinase inhibitor

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 2 Similar Profiles
N'-nitrosonornicotine Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Chemical activation Chemical Compounds
Viral Vaccines Medicine & Life Sciences
Inhibitory Concentration 50 Medicine & Life Sciences
Amphiphiles Chemical Compounds
Molecules Chemical Compounds
Vaccines Engineering & Materials Science

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Research Output 2012 2019

2 Citations (Scopus)

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N′-Nitrosonornicotine

Li, Y., Ma, B., Cao, Q., Balbo, S., Zhao, L., Upadhyaya, P. & Hecht, S. S., Apr 15 2019, In : Chemical research in toxicology. 32, 4, p. 773-783 11 p.

Research output: Contribution to journalArticle

N'-nitrosonornicotine
DNA Adducts
Rats
Phosphates
DNA
2 Citations (Scopus)

Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates

Van Herck, S., Deswarte, K., Nuhn, L., Zhong, Z., Portela Catani, J. P., Li, Y., Sanders, N. N., Lienenklaus, S., De Koker, S., Lambrecht, B. N., David, S. A. & De Geest, B. G., Jan 1 2018, (Accepted/In press) In : Journal of the American Chemical Society.

Research output: Contribution to journalArticle

Amphiphiles
Micelles
Block copolymers
Lymph Nodes
Chemical activation
11 Citations (Scopus)

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Nuhn, L., De Koker, S., Van Lint, S., Zhong, Z., Catani, J. P., Combes, F., Deswarte, K., Li, Y., Lambrecht, B. N., Lienenklaus, S., Sanders, N. N., David, S. A., Tavernier, J. & De Geest, B. G., Nov 8 2018, In : Advanced Materials. 30, 45, 1803397.

Research output: Contribution to journalArticle

Tumors
Chemical activation
Nanoparticles
T-cells
Medical nanotechnology
15 Citations (Scopus)

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Nuhn, L., Van Hoecke, L., Deswarte, K., Schepens, B., Li, Y., Lambrecht, B. N., De Koker, S., David, S. A., Saelens, X. & De Geest, B. G., Sep 1 2018, In : Biomaterials. 178, p. 643-651 9 p.

Research output: Contribution to journalArticle

Viral Vaccines
Vaccines
Cancer Vaccines
Subunit Vaccines
Molecules
31 Citations (Scopus)

Small molecule discoidin domain receptor kinase inhibitors and potential medical applications

Li, Y., Lu, X., Ren, X. & Ding, K., Apr 23 2015, In : Journal of Medicinal Chemistry. 58, 8, p. 3287-3301 15 p.

Research output: Contribution to journalArticle

Phosphotransferases
Ligands
Second Primary Neoplasms
Receptor Protein-Tyrosine Kinases
Drug Discovery