Yuk Y Sham

1995 …2023
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Projects 2013 2023

Research Output 1995 2019

Modeling and Simulation of hGAT1: A Mechanistic Investigation of the GABA Transport Process

Zafar, S., Nguyen, M. E., Muthyala, R., Jabeen, I. & Sham, Y. Y., Jan 1 2019, In : Computational and Structural Biotechnology Journal. 17, p. 61-69 9 p.

Research output: Contribution to journalArticle

gamma-Aminobutyric Acid
Ions
Conformations
Binding sites
Sodium

Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21

Sahu, B. S., Rodriguez, P., Nguyen, M. E., Han, R., Cero, C., Razzoli, M., Piaggi, P., Laskowski, L. J., Pavlicev, M., Muglia, L., Mahata, S. K., O'Grady, S. M., McCorvy, J. D., Baier, L. J., Sham, Y. Y. & Bartolomucci, A., Sep 3 2019, In : Cell reports. 28, 10, p. 2567-2580.e6

Research output: Contribution to journalArticle

Open Access
Complement C3a
Drug therapy
Peptide Receptors
Neuropeptides
Molecular dynamics
2 Citations (Scopus)

An Indole-Chalcone Inhibits Multidrug-Resistant Cancer Cell Growth by Targeting Microtubules

Cong, H., Zhao, X., Castle, B. T., Pomeroy, E. J., Zhou, B., Lee, J., Wang, Y., Bian, T., Miao, Z., Zhang, W., Sham, Y. Y., Odde, D. J., Eckfeldt, C. E., Xing, C. & Zhuang, C., Sep 4 2018, In : Molecular Pharmaceutics. 15, 9, p. 3892-3900 9 p.

Research output: Contribution to journalArticle

Chalcone
Microtubules
Tubulin
Growth
Neoplasms
5 Citations (Scopus)

Aptamer adaptive binding assessed by stilbene photoisomerization towards regenerating aptasensors

Zhou, Y., Wu, Y., Pokholenko, O., Grimsrud, M., Sham, Y. Y., Papper, V., Marks, R. & Steele, T., Mar 1 2018, In : Sensors and Actuators, B: Chemical. 257, p. 245-255 11 p.

Research output: Contribution to journalArticle

Photoisomerization
Stilbenes
stilbene
Fluorescence
fluorescence
3 Citations (Scopus)

Can 5-methylcytosine analogues with extended alkyl side chains guide DNA methylation?

Kotandeniya, D., Seiler, C. L., Fernandez, J., Pujari, S. S., Curwick, L., Murphy, K., Wickramaratne, S., Yan, S., Murphy, D., Sham, Y. Y. & Tretyakova, N. Y., Jan 1 2018, In : Chemical Communications. 54, 9, p. 1061-1064 4 p.

Research output: Contribution to journalArticle

Open Access
5-Methylcytosine
DNA
Methylation
Methyltransferases
Cytosine