Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Functional Dissection of Metabolic-Sensing Proline Hydroxylation Pathways
Chen, Y. (PI)
NIH NIGMS NATL INST OF GENERAL
2/1/23 → 1/31/29
Project: Research project
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Mechanisms of immunoproteasome-mediated metabolic disorders
Kim, D.-H. (PI) & Chen, Y. (CoI)
NIH NATL INST OF DIABETES/DIG/KIDNEY DIS
5/1/20 → 4/30/25
Project: Research project
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CAREER: Functional Dissection of Ubiquitination Signalin
Chen, Y. (PI)
THE NATIONAL SCIENCE FOUNDATION
3/15/18 → 2/29/24
Project: Research project
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Functional Dissection of Metabolic-Sensing Proline Hydro
Chen, Y. (PI) & Kim, D.-H. (CoI)
NIH NIGMS NATL INST OF GENERAL
9/1/17 → 1/31/23
Project: Research project
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Lysine l-lactylation is the dominant lactylation isomer induced by glycolysis
Zhang, D., Gao, J., Zhu, Z., Mao, Q., Xu, Z., Singh, P. K., Rimayi, C. C., Moreno-Yruela, C., Xu, S., Li, G., Sin, Y. C., Chen, Y., Olsen, C. A., Snyder, N. W., Dai, L., Li, L. & Zhao, Y., Jan 2025, In: Nature Chemical Biology. 21, 1, p. 91-99 9 p., 200187.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
A constitutional isomer selective chemical proteomic strategy for system-wide profiling of protein lysine 5-hydroxylation
Sin, Y. C., Park, M., Griffin, T. J., Yong, J. & Chen, Y., Oct 8 2024, In: Chemical Science. 15, 44, p. 18395-18404 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome
Sun, J., Kim, J. Y., Jun, S., Park, M., de Jong, E., Chang, J. W., Cheng, S., Fan, D., Chen, Y., Griffin, T. J., Lee, J. H., You, H. J., Zhang, W. & Yong, J., Oct 2024, In: Experimental and Molecular Medicine. 56, 10, p. 2145-2161 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Gas Tunnel Engineering of Prolyl Hydroxylase Reprograms Hypoxia Signaling in Cells
Windsor, P., Ouyang, H., Joseph, J. A., Rama Damodaran, A., Chen, Y. & Bhagi-Damodaran, A., Nov 25 2024, In: Angewandte Chemie - International Edition. 63, 48, e202409234.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Improved detection of DNA replication fork-associated proteins
Rivard, R. S., Chang, Y. C., Ragland, R. L., Thu, Y. M., Kassab, M., Mandal, R. S., Van Riper, S. K., Kulej, K., Higgins, L. A., Markowski, T. M., Shang, D., Hedberg, J., Erber, L., Garcia, B., Chen, Y., Bielinsky, A. K. & Brown, E. J., May 28 2024, In: Cell reports. 43, 5, 114178.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations