1990 …2017

Research output per year

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Article
2016

A computational model of flow and species transport in the mesangium

Hunt, S. E., Dorfman, K. D., Segal, Y. & Barocas, V. H., Feb 1 2016, In : American Journal of Physiology - Renal Physiology. 310, 3, p. F222-F229

Research output: Contribution to journalArticle

Cell-matrix interaction during straindependent remodelling of simulated collagen networks

Gyoneva, L., Hovell, C. B., Pewowaruk, R. J., Dorfman, K. D., Segal, Y. & Barocas, V. H., Feb 6 2016, In : Interface Focus. 6, 1, 20150098.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2015

Effect of Supercoiling on the Mechanical and Permeability Properties of Model Collagen IV Networks

Gyoneva, L., Segal, Y., Dorfman, K. D. & Barocas, V. H., Jul 22 2015, In : Annals of Biomedical Engineering. 43, 7, p. 1695-1705 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Effect of vitamin E and memantine on functional decline in Alzheimer disease: The TEAM-AD VA cooperative randomized trial

Dysken, M. W., Sano, M., Asthana, S., Vertrees, J. E., Pallaki, M., Llorente, M., Love, S., Schellenberg, G. D., McCarten, J. R., Malphurs, J., Prieto, S., Chen, P., Loreck, D. J., Trapp, G., Bakshi, R. S., Mintzer, J. E., Heidebrink, J. L., Vidal-Cardona, A., Arroyo, L. M., Cruz, A. R. & 13 others, Zachariah, S., Kowall, N. W., Chopra, M. P., Craft, S., Thielke, S., Turvey, C. L., Woodman, C., Monnell, K. A., Gordon, K., Tomaska, J., Segal, Y., Peduzzi, P. N. & Guarino, P. D., Jan 23 2014, In : JAMA - Journal of the American Medical Association. 311, 1, p. 33-44 12 p.

Research output: Contribution to journalArticle

262 Scopus citations
2013

Mechanical response of wild-type and Alport murine lens capsules during osmotic swelling

Gyoneva, L., Segal, Y., Dorfman, K. D. & Barocas, V. H., Aug 1 2013, In : Experimental Eye Research. 113, p. 87-91 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Quaternary epitopes of α345(IV) collagen initiate alport post-transplant anti-GBM nephritis

Olaru, F., Luo, W., Wang, X. P., Ge, L., Hertz, J. M., Kashtan, C. E., Sado, Y., Segal, Y., Hudson, B. G. & Borza, D. B., May 31 2013, In : Journal of the American Society of Nephrology. 24, 6, p. 889-895 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012
5 Scopus citations

Brief report: Analysis of endogenous Oct4 activation during induced pluripotent stem cell reprogramming using an inducible Oct4 lineage label

Greder, L. V., Gupta, S., Li, S., Abedin, M. J., Sajini, A., Segal, Y., Slack, J. M. W. & Dutton, J. R., Nov 1 2012, In : STEM CELLS. 30, 11, p. 2596-2601 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
2010

Aortic abnormalities in males with Alport syndrome

Kashtan, C. E., Segal, Y., Flinter, F., Makanjuola, D., Gan, J. S. & Watnick, T., Nov 1 2010, In : Nephrology Dialysis Transplantation. 25, 11, p. 3554-3560 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Elasticity of the porcine lens capsule as measured by osmotic swelling

Powell, T. A., Amini, R., Oltean, A., Barnett, V. A., Dorfman, K. D., Segal, Y. & Barocas, V. H., Sep 1 2010, In : Journal of Biomechanical Engineering. 132, 9, 91008-1.

Research output: Contribution to journalArticle

9 Scopus citations

X-inactivation modifies disease severity in female carriers of murine X-linked Alport syndrome

Rheault, M. N., Kren, S. M., Hartich, L. A., Wall, M., Thomas, W., Mesa, H. A., Avner, P., Lees, G. E., Kashtan, C. E. & Segal, Y., Mar 1 2010, In : Nephrology Dialysis Transplantation. 25, 3, p. 764-769 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
2007

Distinct Target-Derived Signals Organize Formation, Maturation, and Maintenance of Motor Nerve Terminals

Fox, M. A., Sanes, J. R., Borza, D. B., Eswarakumar, V. P., Fässler, R., Hudson, B. G., John, S. W. M., Ninomiya, Y., Pedchenko, V., Pfaff, S. L., Rheault, M. N., Sado, Y., Segal, Y., Werle, M. J. & Umemori, H., Apr 6 2007, In : Cell. 129, 1, p. 179-193 15 p.

Research output: Contribution to journalArticle

166 Scopus citations
2004

Effect of aldosterone on renal transforming growth factor-β

Juknevicius, I., Segal, Y., Kren, S., Lee, R. & Hostetter, T. H., Jun 1 2004, In : American Journal of Physiology - Renal Physiology. 286, 6 55-6, p. F1059-F1062

Research output: Contribution to journalArticle

92 Scopus citations

Localization of discoidin domain receptors in rat kidney

Lee, R., Eidman, K. E., Kren, S. M., Hostetter, T. H. & Segal, Y., Jul 1 2004, In : Nephron - Experimental Nephrology. 97, 2, p. e62-e70

Research output: Contribution to journalArticle

25 Scopus citations

Mouse model of X-linked Alport syndrome

Rheault, M. N., Kren, S. M., Thielen, B. K., Mesa, H. A., Crosson, J. T., Thomas, W., Sado, Y., Kashtan, C. & Segal, Y., Jun 1 2004, In : Journal of the American Society of Nephrology. 15, 6, p. 1466-1474 9 p.

Research output: Contribution to journalArticle

82 Scopus citations
2003
14 Scopus citations

Tissue- and developmental stage-specific activation of α5 and α6(IV) collagen expression in the upper gastrointestinal tract of transgenic mice

Herzog, C., Zhuang, L., Gorgan, L., Segal, Y. & Zhou, J., Nov 14 2003, In : Biochemical and Biophysical Research Communications. 311, 2, p. 553-560 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2002

Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2

Delmas, P., Nomura, H., Li, X., Lakkis, M., Luo, Y., Segal, Y., Fernández-Fernández, J. M., Harris, P., Frischauf, A. M., Brown, D. A. & Zhou, J., Mar 29 2002, In : Journal of Biological Chemistry. 277, 13, p. 11276-11283 8 p.

Research output: Contribution to journalArticle

141 Scopus citations
2001

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca2+ homeostasis in polycystic kidney disease

Vassilev, P. M., Kanazirska, M., Ye, C. P., Brown, E. M., Guo, L., Chen, X. Z., Segal, Y., Peng, J. B., Basora, N., Babakhanlou, H., Cruger, G., Hediger, M. A. & Zhou, J., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 282, 1, p. 341-350 10 p.

Research output: Contribution to journalArticle

185 Scopus citations

Regulation of the paired type IV collagen genes COL4A5 and COL4A6. Role of the proximal promoter region

Segal, Y., Zhuang, L., Rondeau, E., Sraer, J. D. & Zhou, J., Apr 13 2001, In : Journal of Biological Chemistry. 276, 15, p. 11791-11797 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Transport function of the naturally occurring pathogenic polycystin-2 mutant, R742X

Chen, X. Z., Segal, Y., Basora, N., Guo, L., Peng, J. B., Babakhanlou, H., Vassilev, P. M., Brown, E. M., Hediger, M. A. & Zhou, J., Jan 1 2001, In : Biochemical and Biophysical Research Communications. 282, 5, p. 1251-1256 6 p.

Research output: Contribution to journalArticle

62 Scopus citations
1999

LINE-1 elements at the sites of molecular rearrangements in Alport syndrome-diffuse leiomyomatosis

Segal, Y., Peissel, B., Renieri, A., De Marchi, M., Ballabio, A., Pei, Y. & Zhou, J., Jan 1 1999, In : American Journal of Human Genetics. 64, 1, p. 62-69 8 p.

Research output: Contribution to journalArticle

93 Scopus citations

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions

Chen, X. Z., Vassilev, P. M., Basora, N., Peng, J. B., Nomura, H., Segal, Y., Brown, E. M., Reeders, S. T., Hediger, M. A. & Zhou, J., Sep 23 1999, In : Nature. 401, 6751, p. 383-386 4 p.

Research output: Contribution to journalArticle

186 Scopus citations
1998

Expression of mRNA for type IV collagen α1, α5 and α6 chains by cultured dermal fibroblasts from patients with X-linked Alport syndrome

Sasaki, S., Zhou, B., Fan, W. W., Kim, Y., Barker, D. F., Denison, J. C., Atkin, C. L., Gregory, M. C., Zhou, J., Segal, Y., Sado, Y., Ninomiya, Y., Michael, A. F. & Kashtan, C. E., Aug 1998, In : Matrix Biology. 17, 4, p. 279-291 13 p.

Research output: Contribution to journalArticle

14 Scopus citations
1997

Distribution and developmentally regulated expression of murine polycystin

Segal, Y., Pavlova, A., Barros, E. J. G., Löhning, C., Weining, L. U., Nigam, S. K., Frischauf, A. M., Reeders, S. T. & Zhou, J., 1997, In : American Journal of Physiology. 272, 4 PART 2

Research output: Contribution to journalArticle

67 Scopus citations
1996

Identification and localization of polycystin, the PKD1 gene product

Geng, L., Segal, Y., Peissel, B., Deng, N., Pei, Y., Carone, F., Rennke, H. G., Glücksmann-Kuis, A. M., Schneider, M. C., Ericsson, M., Reeders, S. T. & Zhou, J., Dec 15 1996, In : Journal of Clinical Investigation. 98, 12, p. 2674-2682 9 p.

Research output: Contribution to journalArticle

163 Scopus citations
1993

cAMP-activated apical membrane chloride channels in Necturus gallbladder epithelium

Copello, J., Heming, T. A., Segal, Y. & Reuss, L., Aug 1 1993, In : Journal of General Physiology. 102, 2, p. 177-199 23 p.

Research output: Contribution to journalArticle

30 Scopus citations
1991

Ba2+ release from soda glass modifies single maxi K+ channel activity in patch clamp experiments

Copello, J., Simon, B., Segal, Y., Wehner, F., Ramanujam, V. M., Alcock, N. & Reuss, L., Jan 1 1991, In : Biophysical journal. 60, 4, p. 931-941 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Cytosolic pH regulates maxi K+ channels in Necturus gall‐bladder epithelial cells.

Copello, J., Segal, Y. & Reuss, L., Mar 1 1991, In : The Journal of Physiology. 434, 1, p. 577-590 14 p.

Research output: Contribution to journalArticle

30 Scopus citations

Regulation of ion transport across gallbladder epithelium

Reuss, L., Segal, Y. & Altenberg, G., Jan 1 1991, In : Annual Review of Physiology. 53, 1, p. 361-373 13 p.

Research output: Contribution to journalArticle

20 Scopus citations
1990

A nonenzymatic preparation of epithelial basolateral membrane for patch clamp

Wehner, F., Garretson, L., Dawson, K., Segal, Y. & Reuss, L., Jul 20 1990, In : American Journal of Physiology - Cell Physiology. 258, 6 27-6, p. C1159-C1164

Research output: Contribution to journalArticle

5 Scopus citations
19 Scopus citations

Electrophysiological methods for studying ion and water transport in Necturus gall bladder epithelium

Altenberg, G., Copello, J., Cotton, C., Dawson, K., Segal, Y., Wehner, F. & Reuss, L., Jan 1 1990, In : Methods in enzymology. 192, C, p. 650-683 34 p.

Research output: Contribution to journalArticle

14 Scopus citations

Maxi K+ channels and their relationship to the apical membrane conductance in necturus gallbladder epithelium

Segal, Y. & Reuss, L., May 1 1990, In : Journal of General Physiology. 95, 5, p. 791-818 28 p.

Research output: Contribution to journalArticle

29 Scopus citations