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Research Output 1995 2019

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Article
2019
1 Citation (Scopus)

Novel role of mitochondrial GTPases 1 in pathological cardiac hypertrophy

Xu, D., Zhao, Y., Weng, X., Lu, Y., Li, W., Tang, K., Chen, W., Liu, Z., Qi, X., Zheng, J., Fassett, J., Zhang, Y. & Xu, Y., Mar 2019, In : Journal of Molecular and Cellular Cardiology. 128, p. 105-116 12 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Cardiomegaly
Hypertrophy
Cardiac Myocytes
Oxidative Stress
2017

A comparison study between the saturation-recovery-T1 and CASL MRI methods for quantitative CBF imaging

Wang, X., Zhu, X. H., Zhang, Y., Divani, A. A., Murphy, A. J. & Chen, W., Apr 1 2017, In : Magnetic Resonance Imaging. 37, p. 179-186 8 p.

Research output: Contribution to journalArticle

Open Access
Cerebrovascular Circulation
Magnetic resonance imaging
Blood
Imaging techniques
Recovery
7 Citations (Scopus)

Quantitative assessment of brain glucose metabolic rates using in vivo deuterium magnetic resonance spectroscopy

Lu, M., Zhu, X-H., Zhang, Y., Mateescu, G. & Chen, W., Nov 1 2017, In : Journal of Cerebral Blood Flow and Metabolism. 37, 11, p. 3518-3530 13 p.

Research output: Contribution to journalArticle

Open Access
Deuterium
Magnetic Resonance Spectroscopy
Glucose
Brain
Anaerobiosis
2016
3 Citations (Scopus)

Focal middle cerebral artery ischemia in rats via a transfemoral approach using a custom designed microwire

Divani, A. A., Chow, R., Sadeghi-Bazargani, H., Murphy, A. J., Nordberg, J. A., Tokarev, J. V., Hevesi, M., Wang, X., Zhu, X. H., Acompanado, T., Edwards, P. A., Zhang, Y. & Chen, W., Jun 2016, In : Journal of NeuroInterventional Surgery. 8, 6, p. 608-614 7 p.

Research output: Contribution to journalArticle

Middle Cerebral Artery Infarction
Middle Cerebral Artery
Brain Ischemia
External Carotid Artery
Wounds and Injuries
26 Citations (Scopus)

Intra- and inter-molecular interactions of human galectin-3 : assessment by full-assignment-based NMR

Ippel, H., Miller, M. C., Vértesy, S., Zhang, Y., Cañada, F. J., Suylen, D., Umemoto, K., Romanò, C., Hackeng, T. & Tai, G., 2016, In : Glycobiology. p. 1-16 16 p.

Research output: Contribution to journalArticle

Galectin 3
Molecular interactions
Nuclear magnetic resonance
Peptides
Pyridinolcarbamate
2015
5 Citations (Scopus)

Dynamic correlations between hemodynamic, metabolic, and neuronal responses to acute whole-brain ischemia

Taylor, J. M., Zhu, X. H., Zhang, Y. & Chen, W., Nov 2015, In : NMR in biomedicine. 28, 11, p. 1357-1365 9 p.

Research output: Contribution to journalArticle

Hemodynamics
Brain Ischemia
Oxygenation
Brain
Phosphocreatine
3 Citations (Scopus)

Simultaneous imaging of CBF change and BOLD with saturation-recovery-T1 method

Wang, X., Zhu, X. H., Zhang, Y. & Chen, W., Apr 23 2015, In : PloS one. 10, 4, e0122563.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Oxygenation
blood flow
Blood
image analysis
2014
24 Citations (Scopus)

Intracellular redox state revealed by in vivo 31P MRS measurement of NAD+ and NADH contents in brains

Lu, M., Zhu, X. H., Zhang, Y. & Chen, W., Jun 2014, In : Magnetic resonance in medicine. 71, 6, p. 1959-1972 14 p.

Research output: Contribution to journalArticle

NAD
Oxidation-Reduction
Brain
Cats
Brain Diseases
2013
18 Citations (Scopus)

In vitro and in vivo studies of 17O NMR sensitivity at 9.4 and 16.4 T

Lu, M., Zhang, Y., Ugurbil, K., Chen, W. & Zhu, X. H., Jun 1 2013, In : Magnetic resonance in medicine. 69, 6, p. 1523-1527 5 p.

Research output: Contribution to journalArticle

Signal-To-Noise Ratio
Brain
Oxygen Consumption
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
7 Citations (Scopus)
Cerebrovascular Circulation
Perfusion
Oxygen
Magnetic Resonance Spectroscopy
Brain Diseases
51 Citations (Scopus)

The change of functional connectivity specificity in rats under various anesthesia levels and its neural origin

Liu, X., Zhu, X. H., Zhang, Y. & Chen, W., Jul 1 2013, In : Brain Topography. 26, 3, p. 363-377 15 p.

Research output: Contribution to journalArticle

Anesthesia
Isoflurane
Brain
Unconsciousness
Electroencephalography
2012
4 Citations (Scopus)

Large enhancement of perfusion contribution on fMRI signal

Wang, X., Zhu, X. H., Zhang, Y. & Chen, W., May 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 5, p. 907-918 12 p.

Research output: Contribution to journalArticle

Perfusion
Magnetic Resonance Imaging
Hypercapnia
Noise
Brain Mapping
6 Citations (Scopus)

Measurement of Arterial Input Function in Hyperpolarized 13C Studies

Marjańska, M., Teisseyre, T. Z., Halpern-Manners, N. W., Zhang, Y., Iltis, I., Bajaj, V., Ugurbil, K., Pines, A. & Henry, P. G., Jul 1 2012, In : Applied Magnetic Resonance. 43, 1-2, p. 289-297 9 p.

Research output: Contribution to journalArticle

pyruvates
lactates
metabolism
arteries
organs
6 Citations (Scopus)
Adenosinetriphosphate
Rats
Magnetization
Brain
Adenosine Triphosphate
9 Citations (Scopus)
Blood Glucose
Magnetic Resonance Spectroscopy
Glucose
Brain
Isoflurane
2011
102 Citations (Scopus)

Neural origin of spontaneous hemodynamic fluctuations in rats under burst-suppression anesthesia condition

Liu, X., Zhu, X. H., Zhang, Y. & Chen, W., Feb 1 2011, In : Cerebral Cortex. 21, 2, p. 374-384 11 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Anesthesia
Hemodynamics
Oxygen
Electroencephalography
2010
14 Citations (Scopus)

High-resolution fMRI mapping of ocular dominance layers in cat lateral geniculate nucleus

Zhang, N., Zhu, X. H., Zhang, Y., Park, J. K. & Chen, W., May 1 2010, In : NeuroImage. 50, 4, p. 1456-1463 8 p.

Research output: Contribution to journalArticle

ocular Dominance
Geniculate Bodies
Cats
Magnetic Resonance Imaging
Noise
2009
29 Citations (Scopus)

Advanced in vivo heteronuclear MRS approaches for studying brain bioenergetics driven by mitochondria

Zhu, X. H., Du, F., Zhang, N., Zhang, Y., Lei, H., Zhang, X., Qiao, H., Ugurbil, K. & Chen, W., 2009, In : Methods in Molecular Biology. 489, p. 317-357 41 p.

Research output: Contribution to journalArticle

Energy Metabolism
Mitochondria
Magnetic Resonance Spectroscopy
Brain
Biomedical Research

Design of quadrature microstrip transmission line volume coil for small animal MRI/fMRI

Li, Y., Zhu, X. H., Zhang, Y., Jiang, X. H. & Chen, W., Aug 20 2009, In : Chinese Journal of Medical Imaging Technology. 25, 8, p. 1485-1487 3 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Brain
Cats
Geniculate Bodies
Mineral Oil
24 Citations (Scopus)
Pentobarbital
Anesthetics
Protons
Anesthesia
Brain
41 Citations (Scopus)
Neuroimaging
Oxygen
Brain
Magnetic Resonance Imaging
Photic Stimulation
2008
7 Citations (Scopus)

An fMRI study of neural interaction in large-scale cortico-thalamic visual network

Zhang, N., Zhu, X. H., Zhang, Y. & Chen, W., Sep 1 2008, In : NeuroImage. 42, 3, p. 1110-1117 8 p.

Research output: Contribution to journalArticle

Geniculate Bodies
Magnetic Resonance Imaging
Brain
Nijmegen Breakage Syndrome
Visual Cortex
91 Citations (Scopus)

Multipotent adult progenitor cells sustain function of ischemic limbs in mice

Aranguren, X. L., McCue, J. D., Hendrickx, B., Zhu, X. H., Du, F., Chen, E., Pelacho, B., Peñuelas, I., Abizanda, G., Uriz, M., Frommer, S. A., Ross, J. J., Schroeder, B. A., Seaborn, M. S., Adney, J. R., Hagenbrock, J., Harris, N. H., Zhang, Y., Zhang, X., Nelson-Holte, M. H. & 6 others, Jiang, Y., Billiau, A. D., Chen, W., Prósper, F., Verfaillie, C. M. & Luttun, A., Feb 1 2008, In : Journal of Clinical Investigation. 118, 2, p. 505-514 10 p.

Research output: Contribution to journalArticle

Blood Vessels
Stem Cells
Extremities
Regeneration
Muscles
107 Citations (Scopus)

Tightly coupled brain activity and cerebral ATP metabolic rate

Du, F., Zhu, X. H., Zhang, Y., Friedman, M., Zhang, N., Uǧurbil, K. & Chen, W., Apr 29 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 17, p. 6409-6414 6 p.

Research output: Contribution to journalArticle

Adenosine Triphosphate
Adenosine Triphosphatases
Brain
Oxidative Phosphorylation
Energy Metabolism
2007
32 Citations (Scopus)
Three-Dimensional Imaging
Hypothermia
Cerebrovascular Circulation
Brain
Brain Diseases
2003
25 Citations (Scopus)
Prosencephalon
Protons
Ischemia
Creatine
Water
14 Citations (Scopus)
Carotid Arteries
Blood Vessels
Water
Electromagnetic Phenomena
Signal-To-Noise Ratio
2002
98 Citations (Scopus)

Development of 17O NMR approach for fast imaging of cerebral metabolic rate of oxygen in rat brain at high field

Zhu, X-H., Zhang, Y., Tian, R. X., Lei, H., Zhang, N., Zhang, X., Merkle, H., Ugurbil, K. & Chen, W., Oct 1 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 20, p. 13194-13199 6 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Oxygen
Brain
Inhalation
Chloralose
1999
13 Citations (Scopus)

In vitro and in vivo studies of 1H NMR visibility to detect deoxyhemoglobin and deoxymyoglobin signals in myocardium

Chen, W., Cho, Y., Merkle, H., Ye, Y., Zhang, Y., Gong, G., Zhang, J. & Ugurbil, K., Jan 1 1999, In : Magnetic resonance in medicine. 42, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Myocardium
Magnetic Resonance Spectroscopy
Pulse
Canidae
Protons
34 Citations (Scopus)

Myocardial creatine kinase kinetics in hearts with postinfarction left ventricular remodeling

Murakami, Y., Zhang, J. J., Eijgelshoven, M. H. J., Chen, W., Carlyle, W. C., Zhang, Y., Gong, G. & Bache, R. J., Mar 1 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 276, 3 45-3

Research output: Contribution to journalArticle

MB Form Creatine Kinase
Ventricular Remodeling
Dobutamine
Creatine Kinase
Heart Failure
53 Citations (Scopus)

Myocardial oxygenation at high workstates in hearts with left ventricular hypertrophy

Bache, R. J., Zhang, J. J., Murakami, Y., Zhang, Y., Cho, Y. K., Merkle, H., Gong, G., From, A. H. & Ugurbil, K., Jun 1 1999, In : Cardiovascular Research. 42, 3, p. 616-626 11 p.

Research output: Contribution to journalArticle

Left Ventricular Hypertrophy
Phosphocreatine
Catecholamines
Workload
Dobutamine
60 Citations (Scopus)

Myocardial oxygenation during high work states in hearts with postinfarction remodeling

Murakami, Y., Zhang, Y., Cho, Y. K., Mansoor, A. M., Chung, J. K., Chu, C., Francis, G. S., Ugurbil, K., Bache, R. J., From, A. H., Jerosch-Herold, M., Wilke, N. & Zhang, J., Feb 23 1999, In : Circulation. 99, 7, p. 942-948 7 p.

Research output: Contribution to journalArticle

Phosphocreatine
Dobutamine
Adenosine Triphosphate
Heart Failure
Ventricular Remodeling
51 Citations (Scopus)

Oxygen delivery does not limit cardiac performance during high work states

Zhang, J., Murakami, Y., Zhang, Y., Cho, Y. K., Ye, Y., Gong, G., Bache, R. J., Uǧurbil, K. & From, A. H. L., Jul 1 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 277, 1 46-1

Research output: Contribution to journalArticle

Phosphocreatine
Phosphates
Oxygen
Coronary Occlusion
Adenosine Triphosphate
1997
34 Citations (Scopus)

Determination of deoxymyoglobin changes during graded myocardial ischemia: An in vivo 1H NMR spectroscopy study

Chen, W., Zhang, J., Eljgelshoven, M. H. J., Zhang, Y., Zhu, X. H., Wang, C., Cho, Y., Merkle, H. & Uĝurbil, K., Aug 1 1997, In : Magnetic resonance in medicine. 38, 2, p. 193-197 5 p.

Research output: Contribution to journalArticle

Myocardial Ischemia
Magnetic Resonance Spectroscopy
Coronary Occlusion
Protons
Canidae
25 Citations (Scopus)

Myocardial bioenergetics during acute hibernation

Zhang, J., Ishibashi, Y., Zhang, Y., Eijgelshoven, M. H. J., Duncker, D. J., Merkle, H., Bache, R. J., Ugurbil, K. & From, A. H. L., 1997, In : American Journal of Physiology - Heart and Circulatory Physiology. 273, 3, p. H1452-H1463

Research output: Contribution to journalArticle

Hibernation
Phosphocreatine
Energy Metabolism
Adenosine Triphosphate
Blood Pressure
40 Citations (Scopus)

Relationships between myocardial bioenergetic and left ventricular function in hearts with volume-overload hypertrophy

Zhang, J. J., Toher, C., Erhard, M., Zhang, Y., Ugurbil, K., Bache, R. J., Lange, T. & Homans, D. C., Jul 1 1997, In : Circulation. 96, 1, p. 334-343 10 p.

Research output: Contribution to journalArticle

Cardiac Volume
Mitral Valve Insufficiency
Left Ventricular Function
Hypertrophy
Energy Metabolism
1996
111 Citations (Scopus)

Functional and bioenergetic consequences of postinfarction left ventricular remodeling in a new porcine model MRI and 31P-MRS study

Zhang, J., Wilke, N., Wang, Y., Zhang, Y., Wang, C., Eijgelshoven, M. H. J., Cho, Y. K., Murakami, Y., Ugurbil, K., Bache, R. J. & From, A. H., Jan 1 1996, In : Circulation. 94, 5, p. 1089-1100 12 p.

Research output: Contribution to journalArticle

Ventricular Remodeling
Energy Metabolism
Swine
Heart Failure
Phosphocreatine
127 Citations (Scopus)

Modeling regional myocardial flows from residue functions of an intravascular indicator

Kroll, K., Wilke, N., Jerosch-Herold, M., Wang, Y., Zhang, Y., Bache, R. J. & Bassingthwaighte, J. B., Oct 1996, In : American Journal of Physiology - Heart and Circulatory Physiology. 271, 4, p. H1643-H1655

Research output: Contribution to journalArticle

Blood Vessels
Regional Blood Flow
Left Atrial Function
Magnetic Resonance Imaging
Dogs
68 Citations (Scopus)

Myocardial perfusion and function in dogs with moderate coronary stenosis

Kraitchman, D. L., Wilke, N., Hexeberg, E., Jerosch-Herold, M., Wang, Y., Parrish, T. B., Chang, C. N., Zhang, Y., Bache, R. J. & Axel, L., May 1 1996, In : Magnetic resonance in medicine. 35, 5, p. 771-780 10 p.

Research output: Contribution to journalArticle

Dobutamine
Coronary Stenosis
Perfusion
Dogs
Regional Blood Flow
1995
78 Citations (Scopus)

Effect of left ventricular hypertrophy secondary to chronic pressure overload on transmural myocardial 2-deoxyglucose uptake: A 31P NMR spectroscopic study

Zhang, J., Duncker, D. J., Ya, X., Zhang, Y., Pavek, T., Wei, H., Merkle, H., Ugurbil, K., From, A. H. & Bache, R. J., Jan 1 1995, In : Circulation. 92, 5, p. 1274-1283 10 p.

Research output: Contribution to journalArticle

Deoxyglucose
Left Ventricular Hypertrophy
Magnetic Resonance Spectroscopy
Pressure
Phosphocreatine
50 Citations (Scopus)

Fast anatomical imaging of the heart and assessment of myocardial perfusion with arrhythmia insensitive magnetization preparation

Tsekos, N. V., Zhang, Y., Merkle, H., Wilke, N., Jerosch‐Herold, M., Stillman, A. & Ugurbil, K., Oct 1995, In : Magnetic resonance in medicine. 34, 4, p. 530-536 7 p.

Research output: Contribution to journalArticle

Contrast Media
Cardiac Arrhythmias
Perfusion