19922013

Research output per year

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Research Output

2013
14 Scopus citations
2010

The type i insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival

Sachdev, D., Zhang, X., Matise, I., Gaillard-Kelly, M. & Yee, D., Jan 1 2010, In : Oncogene. 29, 2, p. 251-262 12 p.

Research output: Contribution to journalArticle

71 Scopus citations
2006

Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells

Byron, S. A., Horwitz, K. B., Richer, J. K., Lange, C. A., Zhang, X. & Yee, D., Nov 6 2006, In : British Journal of Cancer. 95, 9, p. 1220-1228 9 p.

Research output: Contribution to journalArticle

91 Scopus citations
2005

Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration

Zhang, X., Lin, M., Van Golen, K. L., Yoshioka, K., Itoh, K. & Yee, D., Sep 1 2005, In : Breast Cancer Research and Treatment. 93, 2, p. 159-168 10 p.

Research output: Contribution to journalArticle

55 Scopus citations
2004

A Dominant Negative Type I Insulin-like Growth Factor Receptor Inhibits Metastasis of Human Cancer Cells

Sachdev, D., Hartell, J. S., Lee, A. V., Zhang, X. & Yee, D., Feb 6 2004, In : Journal of Biological Chemistry. 279, 6, p. 5017-5024 8 p.

Research output: Contribution to journalArticle

133 Scopus citations

Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression

Zhang, X., Kamaraju, S., Hakuno, F., Kabuta, T., Takahashi, S. I., Sachdev, D. & Yee, D., Jan 1 2004, In : Breast Cancer Research and Treatment. 83, 2, p. 161-170 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Selective activation of insulin receptor substrate-1 and -2 in pleural mesothelioma cells: Association with distinct malignant phenotypes

Hoang, C. D., Zhang, X., Scott, P. D., Guillaume, T. J., Maddaus, M. A., Yee, D. & Kratzke, R. A., Oct 15 2004, In : Cancer Research. 64, 20, p. 7479-7485 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
2003

The type I IGF receptor as a target for breast cancer therapy

Zhang, X. & Yee, D., Jan 1 2003, In : Breast Disease. 17, p. 115-124 10 p.

Research output: Contribution to journalReview article

1 Scopus citations

The α2 and α3 integrins are required for morphologic differentiation of an intestinal epithelial cell line

Zhang, X., Cromwell, J. W., Kunjummen, B. D., Yee, D. & Garcia-Aguilar, J., Apr 1 2003, In : Surgery. 133, 4, p. 429-437 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2002

Insulin-like growth factor binding protein-1 (IGFBP-1) inhibits breast cancer cell motility

Zhang, X. & Yee, D., Aug 1 2002, In : Cancer Research. 62, 15, p. 4369-4375 7 p.

Research output: Contribution to journalArticle

67 Scopus citations
2001

Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines

Jackson, J. G., Zhang, X., Yoneda, T. & Yee, D., Nov 1 2001, In : Oncogene. 20, 50, p. 7318-7325 8 p.

Research output: Contribution to journalArticle

104 Scopus citations
2000

Tyrosine kinase signalling in breast cancer. Insulin-like growth factors and their receptors in breast cancer

Zhang, X. & Yee, D., Dec 1 2000, In : Breast Cancer Research. 2, 3, p. 170-175 6 p.

Research output: Contribution to journalReview article

75 Scopus citations
1996

Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists

Claude, P. A., Wotta, D. R., Zhang, X., Prather, P. L., McGinn, T. M., Erickson, L. J., Loh, H. H. & Law, P-Y., Jun 27 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 12, p. 5715-5719 5 p.

Research output: Contribution to journalArticle

62 Scopus citations
1995

Distribution of Neuropeptide Receptors: New Views of Peptidergic Neurotransmission Made Possible by Antibodies to Opioid Receptors

ELDE, ROBERT., ARVIDSSON, ULF., RIEDL, MAUREEN., VULCHANOVA, LUCY., LEE, JANGHERN. H., DADO, ROBERT., NAKANO, ALBERT., CHAKRABARTI, SUMITA., ZHANG, XU., LOH, HORACE. H., LAW, PING. Y., HÖKFELT, TOMAS. & WESSENDORF, MARTIN., May 1995, In : Annals of the New York Academy of Sciences. 757, 1, p. 390-404 15 p.

Research output: Contribution to journalArticle

61 Scopus citations
1993

Transfection of NG108-15 cells with antisense opioid-binding cell adhesion molecule cDNA alters opioid receptor-G-protein interaction

Govitrapong, P., Zhang, X., Loh, H. H. & Lee, N. M., Jan 1 1993, In : Journal of Biological Chemistry. 268, 24, p. 18280-18285 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
1992

Antisense proenkephalin cDNA transfection decreases opioid binding in NG 108-15 cells

Arany, I., Zhang, X., Loh, H. H. & Lee, N. M., Dec 1992, In : Molecular Brain Research. 16, 3-4, p. 295-302 8 p.

Research output: Contribution to journalArticle

6 Scopus citations