Projects per year
Personal profile
Research interests
Will Mantyh MD is a behavioral neurologist specializing in the diagnosis and care for neurodegenerative disease, such as Alzheimer's disease, Lewy body disease, Frontotemporal dementia, or Chronic Traumatic Encephalopathy. His research expertise is the development of blood and imaging biomarkers for neurodegenerative disease. In particular, he currently seeks to expand the applicability of revolutionary new blood tests for Alzheimer's disease to underrepresented patients and 'real world' settings that are more complicated than clinical trial populations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, University of Minnesota
Award Date: May 10 2014
Fellowship in Behavioral Neurology, University of California San Francisco
2018 → 2020
Neurology Residency, Mayo Clinic
2015 → 2018
Internal Medicine Internship
2014 → 2015
Research Interest Keywords
- Biomarkers
- Neurodegeneration
- alzheimer's disease
- Health disparities
- Neuroimaging
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Dementia prevalence, APOE, and blood-based biomarkers of AD in Native American communities
Mantyh, W., Cayci, Z., Jacklin, K., Johnson, T. M., Lakshminarayan, K., Petersen, A. J. & Smith, B.
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/22 → 4/30/27
Project: Research project
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Detecting synergistic effects of pharmacological and non-pharmacological interventions for AD/ADRD
Zhang, R., Li, L., Mantyh, W. & Wolfson, J.
NIH NAT'L INSTITUTE ON AGING (NIA)
9/1/22 → 5/31/23
Project: Research project
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Bringing Breakthroughs in Alzheimers disease blood-tests and therapies to American Indian communities of Minnesota
Mantyh, W., Henderson, J. N. & Nelson, K.
Winston & Maxine Wallin Neuro Disc Fund
1/1/21 → 12/31/21
Project: Research project
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Deep phenotyping of Alzheimer’s disease leveraging electronic medical records identifies sex-specific clinical associations
Tang, A. S., Oskotsky, T., Havaldar, S., Mantyh, W. G., Bicak, M., Solsberg, C. W., Woldemariam, S., Zeng, B., Hu, Z., Oskotsky, B., Dubal, D., Allen, I. E., Glicksberg, B. S. & Sirota, M., Dec 2022, In: Nature communications. 13, 1, 675.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Plasma P-tau181 and P-tau217 in Patients with Traumatic Encephalopathy Syndrome with and Without Evidence of Alzheimer Disease Pathology
Asken, B. M., Tanner, J. A., Vandevrede, L., Mantyh, W. G., Casaletto, K. B., Staffaroni, A. M., La Joie, R., Iaccarino, L., Soleimani-Meigooni, D., Rojas, J. C., Gardner, R. C., Miller, B. L., Grinberg, L. T., Boxer, A. L., Kramer, J. H. & Rabinovici, G. D., Aug 9 2022, In: Neurology. 99, 6, p. E594-E604Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults
Asken, B. M., Mantyh, W. G., La Joie, R., Strom, A., Casaletto, K. B., Staffaroni, A. M., Apple, A. C., Lindbergh, C. A., Iaccarino, L., You, M., Grant, H., Fonseca, C., Windon, C., Younes, K., Tanner, J., Rabinovici, G. D., Kramer, J. H. & Gardner, R. C., Oct 2021, In: Brain Imaging and Behavior. 15, 5, p. 2417-2425 9 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Heterogeneous distribution of tau pathology in the behavioural variant of Alzheimer's disease
Singleton, E., Hansson, O., Pijnenburg, Y. A. L., La Joie, R., Mantyh, W. G., Tideman, P., Stomrud, E., Leuzy, A., Johansson, M., Strandberg, O., Smith, R., Berendrecht, E., Miller, B. L., Iaccarino, L., Edwards, L., Strom, A., Wolters, E. E., Coomans, E., Visser, D., Golla, S. S. V., & 9 others , Aug 1 2021, In: Journal of Neurology, Neurosurgery and Psychiatry. 92, 8, p. 872-880 9 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes
Townley, R. A., Graff-Radford, J., Mantyh, W. G., Botha, H., Polsinelli, A. J., Przybelski, S. A., Machulda, M. M., Makhlouf, A. T., Senjem, M. L., Murray, M. E., Reichard, R. R., Savica, R., Boeve, B. F., Drubach, D. A., Josephs, K. A., Knopman, D. S., Lowe, V. J., Jack, C. R., Petersen, R. C. & Jones, D. T., 2020, In: Brain Communications. 2, 1, fcaa068.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations