Projects per year
Personal profile
Research interests
Will Mantyh MD is a behavioral neurologist specializing in the diagnosis and care for neurodegenerative disease, such as Alzheimer's disease, Lewy body disease, Frontotemporal dementia, or Chronic Traumatic Encephalopathy. His research expertise is the development of blood and imaging biomarkers for neurodegenerative disease. In particular, he currently seeks to expand the applicability of revolutionary new blood tests for Alzheimer's disease to underrepresented patients and 'real world' settings that are more complicated than clinical trial populations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, University of Minnesota
Award Date: May 10 2014
Fellowship in Behavioral Neurology, University of California San Francisco
2018 → 2020
Neurology Residency, Mayo Clinic
2015 → 2018
Internal Medicine Internship
2014 → 2015
Research Interest Keywords
- Biomarkers
- Neurodegeneration
- alzheimer's disease
- Health disparities
- Neuroimaging
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Collaborations and top research areas from the last five years
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Detecting synergistic effects of pharmacological and non-pharmacological interventions for AD/ADRD
Zhang, R. (PI), Li, L. (CoI), Mantyh, W. (CoI) & Wolfson, J. (CoI)
NIH NAT'L INSTITUTE ON AGING (NIA)
9/1/22 → 5/31/25
Project: Research project
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Dementia prevalence, APOE, and blood-based biomarkers of AD in Native American communities
Mantyh, W. (PI), Cayci, Z. (CoI), Jacklin, K. (CoI), Johnson, T. M. (CoI), Lakshminarayan, K. (CoI), Petersen, A. J. (CoI) & Smith, B. (CoI)
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/22 → 4/30/27
Project: Research project
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Addressing Alzheimer's Disease and Related Dementias Disparities: The American Indigenous Cognitive Assessment (AMICA) Project
Jacklin, K. (PI), Mantyh, W. (CoI) & Warry, W. (CoI)
NIH NAT'L INSTITUTE ON AGING (NIA)
6/1/22 → 5/31/27
Project: Research project
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Linking Connectomics to Biochemical Trajectories of Aging - How the Human Brain Ages Differentially in Key Regions of the Default Mode Network
Mangia, S. (PI), Cayci, Z. (CoI), Hemmy, L. S. (CoI), Mantyh, W. (CoI), Marjanska, M. (CoI), McCarten, J. R. (CoI) & Michaeli, S. (CoI)
UNIVERSITY OF MISSOURI, NATIONAL INSTITUTES OF HEALTH (NIH)
1/19/22 → 7/7/23
Project: Research project
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Bringing Breakthroughs in Alzheimers disease blood-tests and therapies to American Indian communities of Minnesota
Mantyh, W. (PI), Henderson, J. N. (CoI) & Nelson, K. (CoI)
WINSTON & MAXINE WALLIN NEURO DISC FUND
1/1/21 → 12/31/21
Project: Research project
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sTREM2 in discordant CSF Aβ42 and p-tau181
for the Alzheimer's Disease Neuroimaging Initiative, Jan 1 2025, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 17, 1, e70072.Research output: Contribution to journal › Article › peer-review
Open Access -
APOE «4 Allele Frequency Among Cognitively Healthy Members of an Ojibwe Tribal Nation
Block, A. D., Castro, M. R., Hansen, A., Strong, C., Hanes, E., Schomaker, M. L., Matheson, M. J., Hill, A., Peterson, A., Henderson, J. N. & Mantyh, W. G., Feb 13 2024, In: Neurology: Genetics. 10, 2, e200130.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Care needs assessment of older adults with dementia in a semi-rural district in Vietnam: A community-based cross-sectional study
Nguyen, A. N., Nguyen, B. T., Nguyen, B. T., Nguyen, B. T. T., Nguyen, N. T. A., Dang, N. T. K., Nguyen, A. T. P., Nguyen, A. T., Pham, T., Mantyh, W. G., Tran, D., Le, O. T. P. & Park, V. M. T., Mar 2024, In: Psychogeriatrics. 24, 2, p. 249-258 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Cognitive Decline and Other Late-Stage Neurologic Complications in Cockayne Syndrome
Rajamani, G., Stafki, S. A., Daugherty, A. L., Mantyh, W. G., Littel, H. R., Bruels, C. C., Pacak, C. A., Robbins, P. D., Niedernhofer, L. J., Abiona, A., Giunti, P., Mohammed, S., Laugel, V. & Kang, P. B., May 16 2024, In: Neurology: Clinical Practice. 14, 4, e200309.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Repurposing non-pharmacological interventions for Alzheimer's disease through link prediction on biomedical literature
Xiao, Y., Hou, Y., Zhou, H., Diallo, G., Fiszman, M., Wolfson, J., Zhou, L., Kilicoglu, H., Chen, Y., Su, C., Xu, H., Mantyh, W. G. & Zhang, R., Dec 2024, In: Scientific reports. 14, 1, 8693.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations